{"id":"https://openalex.org/W2331907014","doi":"https://doi.org/10.1539/joh1959.28.283","title":"Effects of chromium compounds on the respiratory system. Part 4 Long term inhalation of chromic acid mist in electroplating to ICR female mice.","display_name":"Effects of chromium compounds on the respiratory system. Part 4 Long term inhalation of chromic acid mist in electroplating to ICR female mice.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W2331907014","doi":"https://doi.org/10.1539/joh1959.28.283","mag":"2331907014","pmid":"https://pubmed.ncbi.nlm.nih.gov/3784105"},"language":"ja","primary_location":{"id":"doi:10.1539/joh1959.28.283","doi":"https://doi.org/10.1539/joh1959.28.283","is_oa":true,"landing_page_url":"https://doi.org/10.1539/joh1959.28.283","pdf_url":"https://www.jstage.jst.go.jp/article/joh1959/28/4/28_4_283/_pdf","source":{"id":"https://openalex.org/S4210190918","display_name":"Sangyo Igaku","issn_l":"0047-1879","issn":["0047-1879","1881-1302"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313174","host_organization_name":"Japan Society for Occupational Health","host_organization_lineage":["https://openalex.org/P4310313174"],"host_organization_lineage_names":["Japan Society for Occupational Health"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sangyo Igaku","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/joh1959/28/4/28_4_283/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Shuichi ADACHI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8588240","display_name":"Saitama Medical University","ror":"https://ror.org/04zb31v77","country_code":"JP","type":"education","lineage":["https://openalex.org/I8588240"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shuichi ADACHI","raw_affiliation_strings":["Health ,","P ublic Health, Saitama Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health ,","institution_ids":[]},{"raw_affiliation_string":"P ublic Health, Saitama Medical School","institution_ids":["https://openalex.org/I8588240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109154255","display_name":"Hiroyuki Yoshimura","orcid":"https://orcid.org/0009-0009-1991-5001","observed_orcids":["https://orcid.org/0009-0009-1991-5001"]},"institutions":[{"id":"https://openalex.org/I8588240","display_name":"Saitama Medical University","ror":"https://ror.org/04zb31v77","country_code":"JP","type":"education","lineage":["https://openalex.org/I8588240"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki YOSHIMURA","raw_affiliation_strings":["Health ,","P ublic Health, Saitama Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health ,","institution_ids":[]},{"raw_affiliation_string":"P ublic Health, Saitama Medical School","institution_ids":["https://openalex.org/I8588240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108564761","display_name":"Hiroo Katayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8588240","display_name":"Saitama Medical University","ror":"https://ror.org/04zb31v77","country_code":"JP","type":"education","lineage":["https://openalex.org/I8588240"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroo KATAYAMA","raw_affiliation_strings":["Health ,","P ublic Health, Saitama Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health ,","institution_ids":[]},{"raw_affiliation_string":"P ublic Health, Saitama Medical School","institution_ids":["https://openalex.org/I8588240"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110345711","display_name":"Kazuo Takemoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8588240","display_name":"Saitama Medical University","ror":"https://ror.org/04zb31v77","country_code":"JP","type":"education","lineage":["https://openalex.org/I8588240"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo TAKEMOTO","raw_affiliation_strings":["Health ,","P ublic Health, Saitama Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health ,","institution_ids":[]},{"raw_affiliation_string":"P ublic Health, Saitama Medical School","institution_ids":["https://openalex.org/I8588240"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I8588240"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.25260263,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"28","issue":"4","first_page":"283","last_page":"287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11972","display_name":"Chromium effects and bioremediation","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11972","display_name":"Chromium effects and bioremediation","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.05460000038146973,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromium-exposure","display_name":"chromium exposure","score":0.6299999952316284},{"id":"https://openalex.org/keywords/respiratory-toxicity","display_name":"respiratory toxicity","score":0.48100000619888306},{"id":"https://openalex.org/keywords/electroplating-workers","display_name":"electroplating workers","score":0.7269999980926514},{"id":"https://openalex.org/keywords/nasal-septal-perforation","display_name":"nasal septal perforation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/cilia-loss","display_name":"cilia loss","score":0.7590000033378601},{"id":"https://openalex.org/keywords/squamous-metaplasia","display_name":"squamous metaplasia","score":0.9129999876022339},{"id":"https://openalex.org/keywords/lung-adenoma","display_name":"lung adenoma","score":0.6510000228881836},{"id":"https://openalex.org/keywords/lung-adenocarcinoma","display_name":"lung adenocarcinoma","score":0.9380000233650208}],"concepts":[{"id":"https://openalex.org/C2779644171","wikidata":"https://www.wikidata.org/wiki/Q13400765","display_name":"Respiratory tract","level":3,"score":0.65797358751297},{"id":"https://openalex.org/C2780340842","wikidata":"https://www.wikidata.org/wiki/Q422642","display_name":"Chromic acid","level":2,"score":0.6309359073638916},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.5655696392059326},{"id":"https://openalex.org/C2778981785","wikidata":"https://www.wikidata.org/wiki/Q7581956","display_name":"Squamous metaplasia","level":3,"score":0.5613731145858765},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.5514484643936157},{"id":"https://openalex.org/C2780314925","wikidata":"https://www.wikidata.org/wiki/Q181602","display_name":"Bronchus","level":4,"score":0.5185314416885376},{"id":"https://openalex.org/C6831451","wikidata":"https://www.wikidata.org/wiki/Q192196","display_name":"Mist","level":2,"score":0.48350170254707336},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4564594626426697},{"id":"https://openalex.org/C87568996","wikidata":"https://www.wikidata.org/wiki/Q1428754","display_name":"Respiratory epithelium","level":3,"score":0.4486173391342163},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4446330666542053},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4406803548336029},{"id":"https://openalex.org/C2779357193","wikidata":"https://www.wikidata.org/wiki/Q660713","display_name":"Metaplasia","level":2,"score":0.4238261878490448},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.396539568901062},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31743723154067993},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.21216091513633728},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.20147639513015747},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1815885305404663},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C153294291","wikidata":"https://www.wikidata.org/wiki/Q25261","display_name":"Meteorology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000336","descriptor_name":"Aerosols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001980","descriptor_name":"Bronchi","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002840","descriptor_name":"Chromates","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D004595","descriptor_name":"Electroplating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008813","descriptor_name":"Mice, Inbred ICR","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009300","descriptor_name":"Nasal Septum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011656","descriptor_name":"Pulmonary Emphysema","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D014132","descriptor_name":"Trachea","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1539/joh1959.28.283","doi":"https://doi.org/10.1539/joh1959.28.283","is_oa":true,"landing_page_url":"https://doi.org/10.1539/joh1959.28.283","pdf_url":"https://www.jstage.jst.go.jp/article/joh1959/28/4/28_4_283/_pdf","source":{"id":"https://openalex.org/S4210190918","display_name":"Sangyo Igaku","issn_l":"0047-1879","issn":["0047-1879","1881-1302"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313174","host_organization_name":"Japan Society for Occupational Health","host_organization_lineage":["https://openalex.org/P4310313174"],"host_organization_lineage_names":["Japan Society for Occupational Health"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sangyo Igaku","raw_type":"journal-article"},{"id":"pmid:3784105","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3784105","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sangyo igaku. Japanese journal of industrial health","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1539/joh1959.28.283","doi":"https://doi.org/10.1539/joh1959.28.283","is_oa":true,"landing_page_url":"https://doi.org/10.1539/joh1959.28.283","pdf_url":"https://www.jstage.jst.go.jp/article/joh1959/28/4/28_4_283/_pdf","source":{"id":"https://openalex.org/S4210190918","display_name":"Sangyo Igaku","issn_l":"0047-1879","issn":["0047-1879","1881-1302"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313174","host_organization_name":"Japan Society for Occupational Health","host_organization_lineage":["https://openalex.org/P4310313174"],"host_organization_lineage_names":["Japan Society for Occupational Health"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sangyo Igaku","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2331907014.pdf","grobid_xml":"https://content.openalex.org/works/W2331907014.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W51078423","https://openalex.org/W1512839029","https://openalex.org/W1576023655","https://openalex.org/W1977208375","https://openalex.org/W2002219897","https://openalex.org/W2033837652","https://openalex.org/W2060003213","https://openalex.org/W2070754338","https://openalex.org/W2085051716","https://openalex.org/W2320757724","https://openalex.org/W2413265837"],"related_works":["https://openalex.org/W2034257530","https://openalex.org/W70075448","https://openalex.org/W1988146672","https://openalex.org/W4236454364","https://openalex.org/W2298109436","https://openalex.org/W2054354159","https://openalex.org/W7019650975","https://openalex.org/W7099907426","https://openalex.org/W2461298592","https://openalex.org/W2109157058"],"abstract_inverted_index":{"In":[0,62,153,218],"order":[1],"to":[2,30,142,168,177,190,231,238,242],"determine":[3],"the":[4,7,43,53,63,72,92,95,97,101,110,113,136,154,166,175,185,208,220,236,243],"effect":[5],"on":[6,22],"respiratory":[8,65,246],"system":[9],"of":[10,13,94,100,106,112,118,121,135,157,201,216,245],"long-term":[11],"inhalation":[12],"chromic":[14,31,232],"acid":[15,32,233],"in":[16,71,75,132,146,162,165,172,174,182,184,197,228,248],"electroplating,":[17],"histopathological":[18],"examination":[19],"was":[20,160,210],"performed":[21],"mice":[23,54,77,147,229],"(ICR,":[24],"female,":[25],"n":[26],"=":[27],"50)":[28],"exposed":[29,137,148,230],"mist":[33,234],"for":[34,57,149],"12":[35,50],"months":[36,59,206,213],"(30":[37],"min/d,":[38],"2":[39],"d/wk),":[40],"by":[41],"using":[42],"authors'":[44],"miniaturized":[45],"chromium":[46,249],"electroplating":[47,250],"system.":[48],"After":[49],"months'":[51,85],"exposure,":[52],"were":[55,69,79,89,105,130,195,226],"kept":[56],"6":[58,76],"without":[60],"exposure.":[61,86,217],"upper":[64],"tract,":[66],"round":[67],"perforations":[68,88],"found":[70,196],"nasal":[73,102],"septum":[74],"that":[78,222],"sacrificed":[80,211],"or":[81,124],"died":[82,203],"after":[83,188,214],"10":[84],"The":[87],"located":[90],"near":[91],"point":[93],"septum,":[96,103],"thinnest":[98],"part":[99],"and":[104,115,127,181,207,224],"pin-hole":[107],"sige.":[108],"On":[109],"epithelium":[111],"trachea":[114],"bronchus,":[116],"loss":[117],"cilia,":[119],"proliferation":[120],"goblet":[122],"cells":[123],"basal":[125],"cells,":[126],"squamous":[128],"metaplasia":[129],"observed":[131,161,227],"almost":[133],"all":[134],"mice.":[138],"These":[139],"changes":[140],"appeared":[141],"be":[143],"more":[144],"advanced":[145],"a":[150],"longer":[151],"period.":[152],"lung,":[155],"development":[156],"benign":[158],"adenoma":[159],"one":[163,183,200],"mouse":[164],"6-":[167],"9-months'":[169],"exposure":[170,179],"group,":[171],"three":[173],"10-":[176],"14-months'":[178],"group":[180,186],"examined":[187],"15":[189],"18":[191,212],"months.":[192],"Furthermore,":[193],"adenocarcinomas":[194,225],"two":[198],"mice,":[199],"which":[202],"at":[204],"17":[205],"other":[209],"initiation":[215],"conclusion,":[219],"finding":[221],"adenomas":[223],"suggests":[235],"need":[237],"give":[239],"careful":[240],"attention":[241],"possibility":[244],"cancers":[247],"workers.":[251]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}