{"id":"https://openalex.org/W2330596338","doi":"https://doi.org/10.1016/j.talanta.2016.04.014","title":"Fast and efficient proteolysis by reusable pepsin-encapsulated magnetic sol-gel material for mass spectrometry-based proteomics applications","display_name":"Fast and efficient proteolysis by reusable pepsin-encapsulated magnetic sol-gel material for mass spectrometry-based proteomics applications","publication_year":2016,"publication_date":"2016-04-10","ids":{"openalex":"https://openalex.org/W2330596338","doi":"https://doi.org/10.1016/j.talanta.2016.04.014","mag":"2330596338","pmid":"https://pubmed.ncbi.nlm.nih.gov/27216659"},"language":"en","primary_location":{"id":"doi:10.1016/j.talanta.2016.04.014","doi":"https://doi.org/10.1016/j.talanta.2016.04.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.talanta.2016.04.014","pdf_url":null,"source":{"id":"https://openalex.org/S124795565","display_name":"Talanta","issn_l":"0039-9140","issn":["0039-9140","1873-3573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Talanta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080862165","display_name":"Hac\u0131 Mehmet Kay\u0131l\u0131","orcid":"https://orcid.org/0000-0002-6740-0645","observed_orcids":["https://orcid.org/0000-0002-6740-0645"]},"institutions":[{"id":"https://openalex.org/I224962290","display_name":"\u00c7ank\u0131r\u0131 Karatekin University","ror":"https://ror.org/011y7xt38","country_code":"TR","type":"education","lineage":["https://openalex.org/I224962290"]},{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"H. Mehmet Kayili","raw_affiliation_strings":["Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey; \u00c7ank\u0131r\u0131 Karatekin University, Department of Chemistry, 18100 \u00c7ank\u0131r\u0131, Turkey","Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey","\u00c7ank\u0131r\u0131 Karatekin University, Department of Chemistry, 18100 \u00c7ank\u0131r\u0131, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey; \u00c7ank\u0131r\u0131 Karatekin University, Department of Chemistry, 18100 \u00c7ank\u0131r\u0131, Turkey","institution_ids":["https://openalex.org/I224962290","https://openalex.org/I66514158"]},{"raw_affiliation_string":"Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]},{"raw_affiliation_string":"\u00c7ank\u0131r\u0131 Karatekin University, Department of Chemistry, 18100 \u00c7ank\u0131r\u0131, Turkey","institution_ids":["https://openalex.org/I224962290"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037751733","display_name":"Bekir Salih","orcid":"https://orcid.org/0000-0002-8542-6531","observed_orcids":["https://orcid.org/0000-0002-8542-6531"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Bekir Salih","raw_affiliation_strings":["Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey. Electronic address: bekirsal@gmail.com","Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey. Electronic address: bekirsal@gmail.com","institution_ids":["https://openalex.org/I66514158"]},{"raw_affiliation_string":"Hacettepe University, Department of Chemistry, 06800 Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037751733"],"corresponding_institution_ids":["https://openalex.org/I66514158"],"apc_list":{"value":4610,"currency":"USD","value_usd":4610},"apc_paid":null,"fwci":0.378,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.47474587,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"155","issue":null,"first_page":"78","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.8988999724388123,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.8988999724388123,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.07769999653100967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pepsin","display_name":"pepsin","score":0.8600000143051147},{"id":"https://openalex.org/keywords/enzyme-encapsulation","display_name":"enzyme encapsulation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/protein-digestion","display_name":"protein digestion","score":0.6869999766349792},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.9240000247955322},{"id":"https://openalex.org/keywords/enzyme-reuse","display_name":"enzyme reusability","score":0.7730000019073486},{"id":"https://openalex.org/keywords/bovine-serum-albumin","display_name":"bovine serum albumin","score":0.6790000200271606},{"id":"https://openalex.org/keywords/casein","display_name":"casein","score":0.6420000195503235},{"id":"https://openalex.org/keywords/proteomics-sample-preparation","display_name":"proteomics sample preparation","score":0.609000027179718},{"id":"https://openalex.org/keywords/maldi-tof-mass-spectrometry","display_name":"MALDI-TOF mass spectrometry","score":0.8159999847412109},{"id":"https://openalex.org/keywords/lc-ms-ms","display_name":"LC-MS/MS","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8736029863357544},{"id":"https://openalex.org/C16311235","wikidata":"https://www.wikidata.org/wiki/Q190265","display_name":"Pepsin","level":3,"score":0.755663275718689},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7115649580955505},{"id":"https://openalex.org/C86807702","wikidata":"https://www.wikidata.org/wiki/Q2620381","display_name":"Bovine serum albumin","level":2,"score":0.5368329286575317},{"id":"https://openalex.org/C2777897731","wikidata":"https://www.wikidata.org/wiki/Q424430","display_name":"Whey protein","level":2,"score":0.48037442564964294},{"id":"https://openalex.org/C2778063876","wikidata":"https://www.wikidata.org/wiki/Q192642","display_name":"Myoglobin","level":2,"score":0.47283703088760376},{"id":"https://openalex.org/C38398224","wikidata":"https://www.wikidata.org/wiki/Q48350","display_name":"Sol-gel","level":2,"score":0.45248275995254517},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17796453833580017},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15997782349586487},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.08429637551307678},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.06536266207695007}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002214","descriptor_name":"Capsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005782","descriptor_name":"Gels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010434","descriptor_name":"Pepsin A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058185","descriptor_name":"Magnetite Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059748","descriptor_name":"Proteolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.talanta.2016.04.014","doi":"https://doi.org/10.1016/j.talanta.2016.04.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.talanta.2016.04.014","pdf_url":null,"source":{"id":"https://openalex.org/S124795565","display_name":"Talanta","issn_l":"0039-9140","issn":["0039-9140","1873-3573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Talanta","raw_type":"journal-article"},{"id":"pmid:27216659","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27216659","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Talanta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322628","display_name":"T\u00fcrkiye Bilimler Akademisi","ror":"https://ror.org/00aqt9352"},{"id":"https://openalex.org/F4320323272","display_name":"Hacettepe \u00dcniversitesi","ror":"https://ror.org/04kwvgz42"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W561642443","https://openalex.org/W588161924","https://openalex.org/W1584191319","https://openalex.org/W1908598711","https://openalex.org/W1965283492","https://openalex.org/W1972709401","https://openalex.org/W1977676107","https://openalex.org/W1979000314","https://openalex.org/W1981015999","https://openalex.org/W1987690788","https://openalex.org/W1988788778","https://openalex.org/W1994457713","https://openalex.org/W1996848539","https://openalex.org/W2000288939","https://openalex.org/W2001290593","https://openalex.org/W2001415426","https://openalex.org/W2008162528","https://openalex.org/W2008687461","https://openalex.org/W2009906189","https://openalex.org/W2015205746","https://openalex.org/W2017168540","https://openalex.org/W2017590309","https://openalex.org/W2023096047","https://openalex.org/W2035630437","https://openalex.org/W2038666867","https://openalex.org/W2039591679","https://openalex.org/W2040915778","https://openalex.org/W2044468923","https://openalex.org/W2057846273","https://openalex.org/W2069467167","https://openalex.org/W2072266138","https://openalex.org/W2079446152","https://openalex.org/W2094825003","https://openalex.org/W2109950581","https://openalex.org/W2124283227","https://openalex.org/W2147024375","https://openalex.org/W2149177401","https://openalex.org/W2152687832","https://openalex.org/W2156249239","https://openalex.org/W2170036411","https://openalex.org/W2469524263","https://openalex.org/W4244773197","https://openalex.org/W7073787038"],"related_works":["https://openalex.org/W1988788778","https://openalex.org/W2021674382","https://openalex.org/W2323472998","https://openalex.org/W2755824001","https://openalex.org/W2728981321","https://openalex.org/W2132915027","https://openalex.org/W2025180882","https://openalex.org/W2064283682","https://openalex.org/W2965891560","https://openalex.org/W2113549698"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}