{"id":"https://openalex.org/W2329600968","doi":"https://doi.org/10.1093/ajcp/77.5.587","title":"Clinical Laboratory Evaluation of the Thermonuclease Test","display_name":"Clinical Laboratory Evaluation of the Thermonuclease Test","publication_year":1982,"publication_date":"1982-05-01","ids":{"openalex":"https://openalex.org/W2329600968","doi":"https://doi.org/10.1093/ajcp/77.5.587","mag":"2329600968","pmid":"https://pubmed.ncbi.nlm.nih.gov/6805307"},"language":"en","primary_location":{"id":"doi:10.1093/ajcp/77.5.587","doi":"https://doi.org/10.1093/ajcp/77.5.587","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/77.5.587","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019448625","display_name":"Carol J. Shanholtzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carol J. Shanholtzer","raw_affiliation_strings":["Microbiology Section, Department of Laboratory Medicine Veterans Administration Medical Center, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology Section, Department of Laboratory Medicine Veterans Administration Medical Center, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I4210140408"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026183066","display_name":"Lance R. Peterson","orcid":"https://orcid.org/0000-0001-5279-4752","observed_orcids":["https://orcid.org/0000-0001-5279-4752"]},"institutions":[{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lance R. Peterson","raw_affiliation_strings":["Microbiology Section, Department of Laboratory Medicine Veterans Administration Medical Center, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology Section, Department of Laboratory Medicine Veterans Administration Medical Center, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I4210140408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210140408"],"apc_list":{"value":4660,"currency":"USD","value_usd":4660},"apc_paid":null,"fwci":1.6668,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.82580645,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"77","issue":"5","first_page":"587","last_page":"591"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.5845000147819519,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.5845000147819519,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.4146000146865845,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9520000219345093},{"id":"https://openalex.org/keywords/bacterial-identification","display_name":"bacterial identification","score":0.9700000286102295},{"id":"https://openalex.org/keywords/gram-positive-cocci","display_name":"Gram-positive cocci","score":0.7749999761581421},{"id":"https://openalex.org/keywords/coagulase","display_name":"coagulase","score":0.7509999871253967},{"id":"https://openalex.org/keywords/dnase","display_name":"DNase","score":0.9309999942779541},{"id":"https://openalex.org/keywords/clumping-factor","display_name":"clumping factor","score":0.9819999933242798},{"id":"https://openalex.org/keywords/catalase-activity","display_name":"catalase activity","score":0.7239999771118164},{"id":"https://openalex.org/keywords/rapid-identification","display_name":"rapid identification","score":0.34200000762939453}],"concepts":[{"id":"https://openalex.org/C8408860","wikidata":"https://www.wikidata.org/wiki/Q1755077","display_name":"Coagulase","level":5,"score":0.7666805982589722},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.7452461123466492},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6154454350471497},{"id":"https://openalex.org/C2778659741","wikidata":"https://www.wikidata.org/wiki/Q420690","display_name":"Deoxyribonuclease","level":3,"score":0.5895271301269531},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4575537443161011},{"id":"https://openalex.org/C2779288629","wikidata":"https://www.wikidata.org/wiki/Q199695","display_name":"Staphylococcus","level":4,"score":0.44170570373535156},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.17282024025917053},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.12012457847595215},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08579963445663452},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0611882209777832}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001431","descriptor_name":"Bacteriological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003030","descriptor_name":"Coagulase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D003851","descriptor_name":"Deoxyribonucleases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005285","descriptor_name":"Fermentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008353","descriptor_name":"Mannitol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008835","descriptor_name":"Micrococcaceae","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008836","descriptor_name":"Micrococcal Nuclease","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/ajcp/77.5.587","doi":"https://doi.org/10.1093/ajcp/77.5.587","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/77.5.587","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},{"id":"pmid:6805307","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6805307","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of clinical pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1562303387","https://openalex.org/W1582624429","https://openalex.org/W1592177728","https://openalex.org/W1693155018","https://openalex.org/W1879831239","https://openalex.org/W1989749077","https://openalex.org/W2101481866"],"related_works":["https://openalex.org/W1952051867","https://openalex.org/W1537337956","https://openalex.org/W1523112527","https://openalex.org/W2418005775","https://openalex.org/W2101481866","https://openalex.org/W2739546995","https://openalex.org/W2065867847","https://openalex.org/W1562303387","https://openalex.org/W1515100570","https://openalex.org/W1600835749"],"abstract_inverted_index":{"Simultaneous":[0],"testing":[1],"for":[2,34,96,142,150,158],"clumping":[3],"factor,":[4],"coagulase,":[5],"deoxyribonuclease,":[6],"and":[7,100,120],"thermonuclease":[8,28,86,101,111,145],"was":[9,113],"performed":[10],"on":[11],"189":[12],"clinical":[13,155],"isolates":[14,57],"of":[15,26,37,50,55,69,78,93,161],"gram-positive":[16],"cocci":[17],"with":[18],"strong":[19],"catalase":[20],"activity":[21],"to":[22,42,115],"determine":[23],"the":[24,27,35,51,56,67,76,159],"suitability":[25],"test":[29,112,123,146],"as":[30,152],"a":[31,106,153],"routine":[32],"procedure":[33,157],"identification":[36,160],"Staphylococcus":[38,162],"aureus.":[39,163],"Positive":[40],"reactions":[41,68,77,95,127],"all":[43],"four":[44],"tests":[45,102],"were":[46,64,73,88,103,140],"exhibited":[47],"by":[48],"72":[49],"strains":[52],"while":[53],"88":[54],"gave":[58,124],"uniformly":[59],"negative":[60],"results.":[61],"Although":[62],"discrepancies":[63],"found":[65,74,114],"between":[66,75,82],"29":[70,79],"organisms,":[71,80],"differences":[72,81],"tube":[83,98],"coagulase":[84,99],"ant":[85],"results":[87],"rare.":[89],"Greater":[90],"than":[91],"90%":[92],"positive":[94],"both":[97],"detected":[104],"within":[105,128],"four-hour":[107],"incubation":[108],"period.":[109],"The":[110,144],"be":[116],"simple,":[117],"reliable,":[118],"inexpensive":[119],"rapid.":[121],"This":[122],"easily":[125],"interpretable":[126],"an":[129],"eight-hour":[130],"workday,":[131],"even":[132],"when":[133],"only":[134],"one":[135],"or":[136],"two":[137],"isolated":[138],"colonies":[139],"used":[141],"testing.":[143],"is":[147],"well":[148],"suited":[149],"use":[151],"primary":[154],"laboratory":[156]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}