{"id":"https://openalex.org/W2329370340","doi":"https://doi.org/10.2957/kanzo.28.1277","title":"Evaluation of asialoglycoprotein receptor-binding, synthetic radiolabeled glycoprotein in estimating hepatic functional reserve.","display_name":"Evaluation of asialoglycoprotein receptor-binding, synthetic radiolabeled glycoprotein in estimating hepatic functional reserve.","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W2329370340","doi":"https://doi.org/10.2957/kanzo.28.1277","mag":"2329370340"},"language":"en","primary_location":{"id":"doi:10.2957/kanzo.28.1277","doi":"https://doi.org/10.2957/kanzo.28.1277","is_oa":true,"landing_page_url":"https://doi.org/10.2957/kanzo.28.1277","pdf_url":"https://www.jstage.jst.go.jp/article/kanzo1960/28/10/28_10_1277/_pdf","source":{"id":"https://openalex.org/S194384443","display_name":"Kanzo","issn_l":"0451-4203","issn":["0451-4203","1881-3593"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4322764925","host_organization_name":"The Japan Society of Hepatology","host_organization_lineage":["https://openalex.org/P4322764925"],"host_organization_lineage_names":["The Japan Society of Hepatology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kanzo","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/kanzo1960/28/10/28_10_1277/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032900701","display_name":"Masatoshi Kudo","orcid":"https://orcid.org/0000-0002-4102-3474","observed_orcids":["https://orcid.org/0000-0002-4102-3474"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masatoshi KUDO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105369455","display_name":"Akio Todo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akio TODO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041912992","display_name":"K Ikekubo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katsuji IKEKUBO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Toshihiko FUKUI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toshihiko FUKUI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073333764","display_name":"Hiroshi Kashida","orcid":"https://orcid.org/0000-0002-9774-9485","observed_orcids":["https://orcid.org/0000-0002-9774-9485"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi KASHIDA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111706347","display_name":"Yasuyoshi Ibuki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuyoshi IBUKI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029715568","display_name":"Katsuhiko FUJIMI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katsuhiko FUJIMI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112642807","display_name":"Shusuke Tomita","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shusuke TOMITA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109289273","display_name":"Hideshi Komori","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hideshi KOMORI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108748319","display_name":"Akio Orino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akio ORINO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043166346","display_name":"David R. Vera","orcid":"https://orcid.org/0000-0001-8253-1099","observed_orcids":["https://orcid.org/0000-0001-8253-1099"]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David R. Vera","raw_affiliation_strings":["Department of Nuclear Medicine, University of California Davis Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, University of California Davis Medical Center","institution_ids":["https://openalex.org/I4210160527"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109899834","display_name":"Robert C. Stadalnik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert C. Stadalnik","raw_affiliation_strings":["Department of Nuclear Medicine, University of California Davis Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, University of California Davis Medical Center","institution_ids":["https://openalex.org/I4210160527"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.29124393,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"10","first_page":"1277","last_page":"1286"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.028300000354647636,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asialoglycoprotein-receptor","display_name":"asialoglycoprotein receptor","score":1.0},{"id":"https://openalex.org/keywords/hepatic-functional-reserve","display_name":"hepatic functional reserve","score":0.859000027179718},{"id":"https://openalex.org/keywords/liver-function-imaging","display_name":"liver function imaging","score":0.5929999947547913},{"id":"https://openalex.org/keywords/receptor-mediated-endocytosis","display_name":"receptor-mediated endocytosis","score":0.8059999942779541},{"id":"https://openalex.org/keywords/time-activity-curves","display_name":"time-activity curves","score":0.6380000114440918},{"id":"https://openalex.org/keywords/liver-function-tests","display_name":"liver function tests","score":0.4650000035762787},{"id":"https://openalex.org/keywords/cholinesterase","display_name":"cholinesterase","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C11569505","wikidata":"https://www.wikidata.org/wiki/Q727265","display_name":"Asialoglycoprotein receptor","level":4,"score":0.8567832708358765},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5477142930030823},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.4203532636165619},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.41446739435195923},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29641473293304443},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.1877746880054474},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.10140076279640198}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2957/kanzo.28.1277","doi":"https://doi.org/10.2957/kanzo.28.1277","is_oa":true,"landing_page_url":"https://doi.org/10.2957/kanzo.28.1277","pdf_url":"https://www.jstage.jst.go.jp/article/kanzo1960/28/10/28_10_1277/_pdf","source":{"id":"https://openalex.org/S194384443","display_name":"Kanzo","issn_l":"0451-4203","issn":["0451-4203","1881-3593"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4322764925","host_organization_name":"The Japan Society of Hepatology","host_organization_lineage":["https://openalex.org/P4322764925"],"host_organization_lineage_names":["The Japan Society of Hepatology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kanzo","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2957/kanzo.28.1277","doi":"https://doi.org/10.2957/kanzo.28.1277","is_oa":true,"landing_page_url":"https://doi.org/10.2957/kanzo.28.1277","pdf_url":"https://www.jstage.jst.go.jp/article/kanzo1960/28/10/28_10_1277/_pdf","source":{"id":"https://openalex.org/S194384443","display_name":"Kanzo","issn_l":"0451-4203","issn":["0451-4203","1881-3593"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4322764925","host_organization_name":"The Japan Society of Hepatology","host_organization_lineage":["https://openalex.org/P4322764925"],"host_organization_lineage_names":["The Japan Society of Hepatology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kanzo","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2329370340.pdf","grobid_xml":"https://content.openalex.org/works/W2329370340.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W1833836425"],"related_works":["https://openalex.org/W2398749397","https://openalex.org/W2358561102","https://openalex.org/W226882710","https://openalex.org/W2082539295","https://openalex.org/W3116600663","https://openalex.org/W2978242848","https://openalex.org/W2460969924","https://openalex.org/W2437755074","https://openalex.org/W1833836425","https://openalex.org/W2335812333"],"abstract_inverted_index":{"Ashwell\u3089\u306b\u3088\u308a\u898b\u51fa\u3055\u308c\u305fasialoglycoprotein":[0],"receptor":[1],"(ASGPR)\u306f\u54fa\u4e73\u52d5\u7269\u306e\u809d\u7d30\u80de\u819c\u8868\u9762\u306b\u306e\u307f\u5c40\u5728\u3057receptor":[2],"mediated":[3],"endocytosis\u3092\u4ecb\u3057\u3066\u7cd6\u30bf\u30f3\u30d1\u30af\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057,\u305d\u306e\u6fc3\u5ea6\u306f\u7a2e\u3005\u306e\u809d\u306e\u75c5\u7684\u72b6\u614b\u306b\u5fdc\u3058\u3066\u5897\u6e1b\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b.\u3053\u306eASGPR\u3092\u3057\u3066\u4ee3\u8b1d\u3055\u308c\u308b\u3053\u3068\u306e\u8a3c\u660e\u3055\u308c\u3066\u3044\u308b\u5408\u6210\u7cd6\u30bf\u30f3\u30d1\u30afGalactosyl":[4],"Neoglycoalbumin":[5],"(NGA)\u309299mTc\u3067\u6a19\u8b58\u3057\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3092\u691c\u8a0e\u3057\u305f.\u81e8\u5e8a\u4f8b23\u4f8b\u3092\u5bfe\u8c61\u306b1.04\u00d710-8mol/kg,":[6],"5mCi\u306e99mTc-NGA\u3092\u6295\u4e0e\u3057\u6295\u4e0e\u5f8c30\u5206\u306b\u304a\u3051\u308b(\u809d\u306e\u653e\u5c04\u6d3b\u6027)\u3068(\u809d+\u5fc3\u306e\u653e\u5c04\u6d3b\u6027)\u306e\u6bd4\u3092NGAReceptor":[7],"Index\u3068\u3057,\u5f93\u6765\u306e\u809d\u6a5f\u80fd\u691c\u67fb\u6cd5\u3068\u6bd4\u8f03\u691c\u8a0e\u3057\u305f.\u305d\u306e\u7d50\u679c,\u5168\u4f8b\u306b\u809d\u306e\u826f\u597d\u306a\u30a4\u30e1\u30fc\u30b8\u304c\u5f97\u3089\u308c\u308b\u3068\u3068\u3082\u306b,NGA":[8],"Receptor":[9],"Index\u306fICG":[10],"15\u5206\u505c\u6ede\u7387\u3068\u306f\u6709\u610f\u306e\u9006\u76f8\u95a2(r=-0.822,":[11],"p<0.001)\u3092\u793a\u3057cholinesterase":[12],"(r=0.812,":[13],"p<0.001),":[14],"hepaplaStin":[15],"test":[16],"(r=0.823,p<0.01)\u3068\u3082\u826f\u3044\u76f8\u95a2\u3092\u793a\u3057\u305f.99mTc-NGA\u306f\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u88fd\u5264\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u306e\u307f\u306a\u3089\u305a,\u305d\u306etime-activity":[17],"curve\u306e\u89e3\u6790\u306b\u3088\u308aASGPR\u6fc3\u5ea6\u3092\u53cd\u6620\u3057\u305f\u809d\u6a5f\u80fd\u4e88\u5099\u529b\u306e\u6307\u6a19\u304c\u5f97\u3089\u308c,\u6709\u7528\u3068\u8003\u3048\u3089\u308c\u305f.":[18]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}