{"id":"https://openalex.org/W2328945004","doi":"https://doi.org/10.1097/imi.0000000000000082","title":"Learning Curve to Lymph Node Resection in Minimally Invasive Esophagectomy for Cancer","display_name":"Learning Curve to Lymph Node Resection in Minimally Invasive Esophagectomy for Cancer","publication_year":2014,"publication_date":"2014-07-01","ids":{"openalex":"https://openalex.org/W2328945004","doi":"https://doi.org/10.1097/imi.0000000000000082","mag":"2328945004","pmid":"https://pubmed.ncbi.nlm.nih.gov/25084251"},"language":"en","primary_location":{"id":"doi:10.1097/imi.0000000000000082","doi":"https://doi.org/10.1097/imi.0000000000000082","is_oa":false,"landing_page_url":"https://doi.org/10.1097/imi.0000000000000082","pdf_url":null,"source":{"id":"https://openalex.org/S131127159","display_name":"Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery","issn_l":"1556-9845","issn":["1556-9845","1559-0879"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056029262","display_name":"Ankit Dhamija","orcid":"https://orcid.org/0000-0002-1679-6336","observed_orcids":["https://orcid.org/0000-0002-1679-6336"]},"institutions":[{"id":"https://openalex.org/I2802646204","display_name":"Morristown Medical Center","ror":"https://ror.org/03m6tev69","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802646204","https://openalex.org/I67339987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ankit Dhamija","raw_affiliation_strings":["Department of Surgery, Morristown Memorial Hospital, Morristown, NJ USA","Section of Thoracic Surgery, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Morristown Memorial Hospital, Morristown, NJ USA","institution_ids":["https://openalex.org/I2802646204"]},{"raw_affiliation_string":"Section of Thoracic Surgery, New Haven, CT USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055877209","display_name":"Joshua E. Rosen","orcid":"https://orcid.org/0000-0002-6416-6582","observed_orcids":["https://orcid.org/0000-0002-6416-6582"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joshua E. Rosen","raw_affiliation_strings":["Section of Thoracic Surgery, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Thoracic Surgery, New Haven, CT USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071419630","display_name":"Anish Dhamija","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802646204","display_name":"Morristown Medical Center","ror":"https://ror.org/03m6tev69","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802646204","https://openalex.org/I67339987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anish Dhamija","raw_affiliation_strings":["Department of Surgery, Morristown Memorial Hospital, Morristown, NJ USA","Section of Thoracic Surgery, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Morristown Memorial Hospital, Morristown, NJ USA","institution_ids":["https://openalex.org/I2802646204"]},{"raw_affiliation_string":"Section of Thoracic Surgery, New Haven, CT USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062252012","display_name":"Bonnie E. Gould Rothberg","orcid":"https://orcid.org/0000-0002-8919-4467","observed_orcids":["https://orcid.org/0000-0002-8919-4467"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bonnie E. Gould Rothberg","raw_affiliation_strings":["Department of Epidemiology, Yale School of Public Health, New Haven, CT USA","Division of Medical Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Yale School of Public Health, New Haven, CT USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Division of Medical Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020232240","display_name":"Anthony W. Kim","orcid":"https://orcid.org/0000-0002-2790-4945","observed_orcids":["https://orcid.org/0000-0002-2790-4945"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anthony W. Kim","raw_affiliation_strings":["Section of Thoracic Surgery, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Thoracic Surgery, New Haven, CT USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019635887","display_name":"Frank C. Detterbeck","orcid":"https://orcid.org/0000-0002-2858-8016","observed_orcids":["https://orcid.org/0000-0002-2858-8016"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frank C. Detterbeck","raw_affiliation_strings":["Section of Thoracic Surgery, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Thoracic Surgery, New Haven, CT USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006849637","display_name":"Daniel J. Boffa","orcid":"https://orcid.org/0000-0001-5471-8833","observed_orcids":["https://orcid.org/0000-0001-5471-8833"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Daniel J. Boffa","raw_affiliation_strings":["Section of Thoracic Surgery, New Haven, CT USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Thoracic Surgery, New Haven, CT USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5006849637"],"corresponding_institution_ids":[],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":1.5649,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.83796915,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"9","issue":"4","first_page":"286","last_page":"291"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/minimally-invasive-esophagectomy","display_name":"minimally invasive esophagectomy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/esophageal-cancer","display_name":"esophageal cancer","score":0.9909999966621399},{"id":"https://openalex.org/keywords/learning-curve","display_name":"learning curve","score":0.9380000233650208},{"id":"https://openalex.org/keywords/lymph-node-yield","display_name":"lymph node yield","score":0.9240000247955322},{"id":"https://openalex.org/keywords/lymph-node-dissection","display_name":"lymph node dissection","score":0.9710000157356262},{"id":"https://openalex.org/keywords/surgical-margins","display_name":"surgical margins","score":0.9490000009536743},{"id":"https://openalex.org/keywords/r0-resection","display_name":"R0 resection","score":0.875},{"id":"https://openalex.org/keywords/surgeon-experience","display_name":"surgeon experience","score":0.8939999938011169},{"id":"https://openalex.org/keywords/high-grade-dysplasia","display_name":"high-grade dysplasia","score":0.8569999933242798},{"id":"https://openalex.org/keywords/oncologic-outcomes","display_name":"oncological outcomes","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8495981693267822},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.6833423376083374},{"id":"https://openalex.org/C2777297899","wikidata":"https://www.wikidata.org/wiki/Q298191","display_name":"Esophagectomy","level":4,"score":0.6588677763938904},{"id":"https://openalex.org/C2780824555","wikidata":"https://www.wikidata.org/wiki/Q1809305","display_name":"Lymphadenectomy","level":3,"score":0.6180429458618164},{"id":"https://openalex.org/C2775894508","wikidata":"https://www.wikidata.org/wiki/Q1128996","display_name":"Dysplasia","level":2,"score":0.47658678889274597},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4763917326927185},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.46225258708000183},{"id":"https://openalex.org/C2779742542","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal cancer","level":3,"score":0.45973408222198486},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.38899877667427063},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.3287632167339325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27875256538391113},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1373673677444458}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008197","descriptor_name":"Lymph Node Excision","qualifier_ui":"Q000193","qualifier_name":"education","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016629","descriptor_name":"Esophagectomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019060","descriptor_name":"Minimally Invasive Surgical Procedures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059032","descriptor_name":"Learning Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/imi.0000000000000082","doi":"https://doi.org/10.1097/imi.0000000000000082","is_oa":false,"landing_page_url":"https://doi.org/10.1097/imi.0000000000000082","pdf_url":null,"source":{"id":"https://openalex.org/S131127159","display_name":"Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery","issn_l":"1556-9845","issn":["1556-9845","1559-0879"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","raw_type":"journal-article"},{"id":"doi:10.1177/155698451400900405","doi":"https://doi.org/10.1177/155698451400900405","is_oa":false,"landing_page_url":"https://doi.org/10.1177/155698451400900405","pdf_url":null,"source":{"id":"https://openalex.org/S131127159","display_name":"Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery","issn_l":"1556-9845","issn":["1556-9845","1559-0879"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","raw_type":"journal-article"},{"id":"pmid:25084251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25084251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Innovations (Philadelphia, Pa.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1666355385","display_name":null,"funder_award_id":"N44CO-2012-0049","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1895915430","display_name":"Prognostic markers in metastatic melanoma","funder_award_id":"5k08ca151645-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6325750694","display_name":null,"funder_award_id":"K08-CA-151645","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320309526","display_name":"Society of Thoracic Surgeons","ror":"https://ror.org/044b6j563"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1965058495","https://openalex.org/W1968096320","https://openalex.org/W1983722137","https://openalex.org/W1993652021","https://openalex.org/W1994642617","https://openalex.org/W1998964953","https://openalex.org/W2024494436","https://openalex.org/W2033113612","https://openalex.org/W2037257526","https://openalex.org/W2054514004","https://openalex.org/W2059918338","https://openalex.org/W2060772190","https://openalex.org/W2079468140","https://openalex.org/W2091636328","https://openalex.org/W2118565029","https://openalex.org/W2126354355","https://openalex.org/W2146805326","https://openalex.org/W2153582318","https://openalex.org/W2165137230","https://openalex.org/W2177194212"],"related_works":["https://openalex.org/W7145134650","https://openalex.org/W3198228547","https://openalex.org/W4322726251","https://openalex.org/W2518817639","https://openalex.org/W3214335153","https://openalex.org/W3164054266","https://openalex.org/W3013192104","https://openalex.org/W3120585603","https://openalex.org/W2127185387","https://openalex.org/W4213173314"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Minimally":[1],"invasive":[2,18],"esophagectomy":[3],"(MIE)":[4],"is":[5,23,230],"a":[6,41,59,148,225],"safe":[7],"alternative":[8],"to":[9,32,44,49,186,204,223],"open":[10],"approaches,":[11],"yet":[12],"the":[13,16,28,46,119,128,158,181,187,241],"impact":[14],"of":[15,27,52,58,121,136,150,195,216],"minimally":[17],"approach":[19],"on":[20],"oncologic":[21,50],"efficacy":[22],"unclear.":[24],"The":[25,66,134,221],"objectives":[26],"current":[29],"study":[30],"were":[31,106,114,213],"compare":[33],"lymph":[34,137,217],"node":[35,218],"yields":[36],"and":[37,86,101,112,153,161,193,235],"surgical":[38],"margins":[39,126],"during":[40,127,140,228],"single-surgeon":[42],"series":[43],"examine":[45],"learning":[47],"curve":[48],"aspects":[51],"MIE.":[53],"METHODS:":[54],"A":[55],"retrospective":[56],"review":[57],"prospectively":[60],"maintained":[61],"institutional":[62],"database":[63],"was":[64,73],"performed.":[65],"sequential":[67],"MIE":[68,96,129,141,229],"experience":[69,130,174,234],"for":[70,97,180],"esophageal":[71],"cancer":[72,98],"subcategorized":[74],"into":[75],"terciles":[76],"(first":[77],"25":[78,243],"MIEs":[79],"as":[80,84,90],"early,":[81,159],"next":[82],"24":[83,89],"middle,":[85,160],"most":[87],"recent":[88],"later).":[91],"RESULTS:":[92],"Seventy-three":[93],"patients":[94],"underwent":[95],"between":[99],"2008":[100],"2013.":[102],"Complete":[103],"resections":[104,123],"(R0)":[105],"performed":[107],"in":[108,118,157,177,200],"71":[109],"cases":[110],"(93%),":[111],"there":[113],"no":[115],"significant":[116,214],"differences":[117],"number":[120,135],"complete":[122,226],"with":[124,144,147],"negative":[125],"(P":[131,165],"=":[132,166,191,211],"0.54).":[133],"nodes":[138,155],"harvested":[139],"increased":[142],"significantly":[143],"progressive":[145],"experience,":[146],"mean":[149],"22,":[151],"29,":[152],"28":[154],"recovered":[156],"late":[162],"subgroups,":[163],"respectively":[164],"0.038).":[167],"On":[168],"multivariate":[169],"analysis,":[170],"only":[171],"increasing":[172],"surgeon":[173,233],"(1.4-fold":[175],"increase":[176],"nodal":[178,201],"yield":[179,202],"latter":[182],"two":[183],"thirds":[184],"relative":[185,203],"first":[188,242],"third,":[189],"P":[190,210],"0.0011)":[192],"histology":[194],"high-grade":[196],"dysplasia":[197],"(0.54-fold":[198],"decrease":[199],"adenocarcinoma":[205],"or":[206],"squamous":[207],"cell":[208],"carcinoma,":[209],"0.025)":[212],"predictors":[215],"yield.":[219],"CONCLUSIONS:":[220],"ability":[222],"execute":[224],"lymphadenectomy":[227],"affected":[231],"by":[232],"improves":[236],"over":[237],"time,":[238],"plateauing":[239],"after":[240],"cases.":[244]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}