{"id":"https://openalex.org/W2328719486","doi":"https://doi.org/10.1016/j.bbmt.2014.11.516","title":"A Randomized Phase II Study of Imatinib and Rituximab for Cutaneous Sclerosis after Allogeneic Hematopoietic Stem Cell Transplantation","display_name":"A Randomized Phase II Study of Imatinib and Rituximab for Cutaneous Sclerosis after Allogeneic Hematopoietic Stem Cell Transplantation","publication_year":2015,"publication_date":"2015-01-22","ids":{"openalex":"https://openalex.org/W2328719486","doi":"https://doi.org/10.1016/j.bbmt.2014.11.516","mag":"2328719486"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2014.11.516","doi":"https://doi.org/10.1016/j.bbmt.2014.11.516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2014.11.516","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbmt.2014.11.516","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040662951","display_name":"Sally Arai","orcid":"https://orcid.org/0000-0003-1993-4172","observed_orcids":["https://orcid.org/0000-0003-1993-4172"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sally Arai","raw_affiliation_strings":["Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112259825","display_name":"Joseph Pidala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Pidala","raw_affiliation_strings":["Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041735776","display_name":"Iskra Pusic","orcid":"https://orcid.org/0000-0003-1725-5184","observed_orcids":["https://orcid.org/0000-0003-1725-5184"]},"institutions":[{"id":"https://openalex.org/I4210135078","display_name":"Washington University Medical Center","ror":"https://ror.org/036c27j91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135078"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iskra Pusic","raw_affiliation_strings":["Medical Oncology, Washington University Medical Center, St. Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Washington University Medical Center, St. Louis, MO","institution_ids":["https://openalex.org/I4210135078"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101688735","display_name":"Xiaoyu Chai","orcid":"https://orcid.org/0000-0002-4894-5543","observed_orcids":["https://orcid.org/0000-0002-4894-5543"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoyu Chai","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072835425","display_name":"Samantha Mary Jaglowski","orcid":"https://orcid.org/0000-0002-4335-2554","observed_orcids":["https://orcid.org/0000-0002-4335-2554"]},"institutions":[{"id":"https://openalex.org/I2802841970","display_name":"The Ohio State University Wexner Medical Center","ror":"https://ror.org/00c01js51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802841970"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samantha Jaglowski","raw_affiliation_strings":["The Ohio State University Medical Center, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Ohio State University Medical Center, Columbus, OH","institution_ids":["https://openalex.org/I2802841970"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057941081","display_name":"Jeanne M. Palmer","orcid":"https://orcid.org/0000-0002-2185-1504","observed_orcids":["https://orcid.org/0000-0002-2185-1504"]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]},{"id":"https://openalex.org/I4210127938","display_name":"Mayo Clinic Hospital","ror":"https://ror.org/03660jn93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4210127938"]},{"id":"https://openalex.org/I4390039332","display_name":"Mayo Clinic Comprehensive Cancer Center (Arizona)","ror":"https://ror.org/003xpy695","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4390039332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeanne Palmer","raw_affiliation_strings":["Hematology Oncology/Blood and Marrow Transplant, Mayo Clinic Arizona, Phoenix, AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology Oncology/Blood and Marrow Transplant, Mayo Clinic Arizona, Phoenix, AZ","institution_ids":["https://openalex.org/I4210125099","https://openalex.org/I4210127938","https://openalex.org/I4390039332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008947160","display_name":"George L. Chen","orcid":"https://orcid.org/0000-0002-7036-2109","observed_orcids":["https://orcid.org/0000-0002-7036-2109"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George L. Chen","raw_affiliation_strings":["Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058557833","display_name":"Nandita Khera","orcid":"https://orcid.org/0000-0002-0577-3155","observed_orcids":["https://orcid.org/0000-0002-0577-3155"]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]},{"id":"https://openalex.org/I4210127938","display_name":"Mayo Clinic Hospital","ror":"https://ror.org/03660jn93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4210127938"]},{"id":"https://openalex.org/I4390039332","display_name":"Mayo Clinic Comprehensive Cancer Center (Arizona)","ror":"https://ror.org/003xpy695","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4390039332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nandita Khera","raw_affiliation_strings":["Hematology Oncology/Blood and Marrow Transplant, Mayo Clinic Arizona, Phoenix, AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology Oncology/Blood and Marrow Transplant, Mayo Clinic Arizona, Phoenix, AZ","institution_ids":["https://openalex.org/I4210125099","https://openalex.org/I4210127938","https://openalex.org/I4390039332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101506577","display_name":"Sebastian Alexander Mayer","orcid":"https://orcid.org/0000-0003-1648-1382","observed_orcids":["https://orcid.org/0000-0003-1648-1382"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sebastian Mayer","raw_affiliation_strings":["Department of Medicine, Weill Cornell Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Weill Cornell Medical Center, New York, NY","institution_ids":["https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070008988","display_name":"Madan Jagasia","orcid":"https://orcid.org/0000-0001-5757-5604","observed_orcids":["https://orcid.org/0000-0001-5757-5604"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Madan H. Jagasia","raw_affiliation_strings":["Division of Hematology/Oncology, Stem Cell Transplantation, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Stem Cell Transplantation, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016014484","display_name":"William Allen Wood","orcid":"https://orcid.org/0000-0001-7439-2543","observed_orcids":["https://orcid.org/0000-0001-7439-2543"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William A. Wood","raw_affiliation_strings":["Division of Hematology/Oncology, University of North Carolina - Chapel Hill, Chapel Hill, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, University of North Carolina - Chapel Hill, Chapel Hill, NC","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059063645","display_name":"Paul J. Martin","orcid":"https://orcid.org/0000-0001-9051-1215","observed_orcids":["https://orcid.org/0000-0001-9051-1215"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul J. Martin","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026533672","display_name":"Yoshihiro Inamoto","orcid":"https://orcid.org/0000-0003-4881-0427","observed_orcids":["https://orcid.org/0000-0003-4881-0427"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoshihiro Inamoto","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081926380","display_name":"David Bernard Miklos","orcid":"https://orcid.org/0000-0003-0717-4305","observed_orcids":["https://orcid.org/0000-0003-0717-4305"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B. Miklos","raw_affiliation_strings":["Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Blood and Marrow Transplantation, Stanford University Medical Center, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031390636","display_name":"Stephanie Joi Lee","orcid":"https://orcid.org/0000-0003-2600-6390","observed_orcids":["https://orcid.org/0000-0003-2600-6390"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie J. Lee","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016644532","display_name":"Mary E.D. Flowers","orcid":"https://orcid.org/0000-0003-1631-0911","observed_orcids":["https://orcid.org/0000-0003-1631-0911"]},"institutions":[{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary E.D. Flowers","raw_affiliation_strings":["Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA","institution_ids":["https://openalex.org/I4210089486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.2604,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.64973964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"21","issue":"2","first_page":"S324","last_page":"S324"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.899399995803833,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.899399995803833,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.039500001817941666,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cutaneous-sclerosis","display_name":"cutaneous sclerosis","score":0.9660000205039978},{"id":"https://openalex.org/keywords/chronic-graft-versus-host-disease","display_name":"chronic graft-versus-host disease","score":0.9909999966621399},{"id":"https://openalex.org/keywords/allogeneic-hematopoietic-stem-cell-transplantation","display_name":"allogeneic hematopoietic stem cell transplantation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/localized-scleroderma","display_name":"morphea","score":0.8429999947547913},{"id":"https://openalex.org/keywords/joint-contractures","display_name":"joint contractures","score":0.9070000052452087},{"id":"https://openalex.org/keywords/crossover-trial","display_name":"crossover trial","score":0.460999995470047},{"id":"https://openalex.org/keywords/b-cell-depletion","display_name":"B-cell depletion","score":0.3409999907016754},{"id":"https://openalex.org/keywords/tyrosine-kinase-inhibitors","display_name":"tyrosine kinase inhibitors","score":0.7039999961853027},{"id":"https://openalex.org/keywords/treatment-response-comparison","display_name":"treatment response comparison","score":0.4429999887943268},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.5509999990463257},{"id":"https://openalex.org/keywords/range-of-motion","display_name":"range of motion","score":0.5669999718666077},{"id":"https://openalex.org/keywords/scleroderma-like-skin-changes","display_name":"scleroderma-like skin changes","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9733445644378662},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.696735680103302},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5282206535339355},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.5158533453941345},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4981966018676758},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4356766641139984},{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.4217525124549866},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.382566899061203},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3270125389099121},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.1313440203666687}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bbmt.2014.11.516","doi":"https://doi.org/10.1016/j.bbmt.2014.11.516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2014.11.516","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2014.11.516","doi":"https://doi.org/10.1016/j.bbmt.2014.11.516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2014.11.516","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4298283946","https://openalex.org/W4399725547","https://openalex.org/W4391615926","https://openalex.org/W1982383053","https://openalex.org/W2561700073","https://openalex.org/W3132861975","https://openalex.org/W2793625995","https://openalex.org/W2583956621","https://openalex.org/W2773152097","https://openalex.org/W3214285101"],"abstract_inverted_index":{"Cutaneous":[0],"sclerosis":[1],"(CS)":[2],"occurs":[3],"in":[4,93,164,300,355,360,436],"20%":[5],"of":[6,22,32,60,91,105,118,129,196,209,295,328],"patients":[7],"(pts)":[8],"with":[9,261,367,391],"chronic":[10,262],"graft-versus-host":[11],"disease":[12],"(cGVHD)":[13],"and":[14,20,42,231,238,253,307,318,342],"can":[15],"severely":[16],"compromise":[17],"patient":[18],"mobility":[19],"quality":[21],"life.":[23],"Prospective,":[24],"multi-center,":[25],"randomized,":[26],"two-arm":[27],"phase":[28],"II":[29],"crossover":[30],"trial":[31],"imatinib":[33,237,306,317,340,369],"(200":[34],"mg":[35],"daily":[36],"by":[37,40,56],"mouth,":[38],"provided":[39,55],"Novartis)":[41],"rituximab":[43,320,347,371],"(375":[44],"mg/m2":[45],"intravenously":[46],"weekly":[47],"x":[48],"4":[49,316,343],"doses,":[50],"repeatable":[51],"after":[52,364],"3":[53,119,319],"months,":[54,144],"Genentech)":[57],"for":[58,184,285,335,372,384,387],"treatment":[59,366,375],"CS":[61,71,178,185],"at":[62,109,122,142,174,198,264,362,410,416],"11":[63],"institutions":[64],"within":[65,84],"the":[66,85,97,110,123,126,136,154,165,205,286,339,346,382,428],"Chronic":[67],"GVHD":[68,263],"Consortium":[69],"(NCT01309997).":[70],"was":[72,135,172,192,245,276,298,358,377],"defined":[73,145,193],"as":[74,146,194],"sclerotic":[75],"skin,":[76],"morphea,":[77],"myofascial":[78],"involvement":[79],"or":[80,102,107,113,115,120,149,159,182,187,211,370,408,432],"joint":[81],"contractures":[82],"diagnosed":[83],"past":[86],"18":[87],"months":[88,176,200,294,395],"(a":[89],"score":[90,104,117],"\u22652":[92],"any":[94],"area":[95],"on":[96,125,153,338,345,351],"Vienna":[98],"Skin":[99],"Score":[100],"(VSS),":[101],"a":[103,116,147,160,437],"5":[106],"less":[108,121,291,392],"shoulders,":[111],"elbows,":[112],"wrists,":[114],"ankles":[124],"photographic":[127],"range":[128],"motion":[130],"(P-ROM)).":[131],"The":[132,242,267],"primary":[133,287],"endpoint":[134],"significant":[137,422],"clinical":[138,398,423],"response":[139,329,424],"(SCR)":[140],"rate":[141],"6":[143,175,199,293,336,394,411,417],"2":[148],"more":[150],"point":[151,162],"improvement":[152,163,354],"VSS":[155],"without":[156,168,201,405],"worsening":[157,169],"elsewhere":[158],"1-2":[161],"P-ROM":[166],"scale":[167],"elsewhere.":[170],"Crossover":[171],"allowed":[173],"if":[177],"did":[179],"not":[180],"improve,":[181],"earlier":[183],"progression":[186],"drug":[188],"intolerance.":[189],"Treatment":[190,332],"success":[191,333,376],"achievement":[195],"SCR":[197,218,297,314,349,404],"crossing":[202],"over":[203,323],"to":[204,236,240,273,305,311,325,427],"second":[206],"medication,":[207],"recurrence":[208],"malignancy":[210],"death.":[212],"With":[213],"37":[214,239],"pts":[215,225,282,303,321],"per":[216],"arm,":[217],"+/-":[219],"15%":[220],"could":[221],"be":[222],"estimated.":[223],"72":[224],"were":[226,251],"enrolled":[227],"between":[228],"March":[229],"2011":[230],"June":[232],"2014,":[233],"35":[234],"randomized":[235,304,310],"rituximab.":[241,312],"median":[243,268],"age":[244],"56":[246],"years":[247],"(range":[248,279],"19-77),":[249],"44%":[250],"female,":[252],"all":[254],"had":[255],"organs":[256],"other":[257,429],"than":[258,292,393],"skin":[259],"involved":[260],"study":[265,274],"enrollment.":[266],"time":[269],"from":[270],"cGVHD":[271],"onset":[272],"enrollment":[275],"1.0":[277],"year":[278],"0-3.8).":[280],"64":[281],"are":[283],"evaluable":[284],"endpoint;":[288],"8":[289],"have":[290],"follow-up.":[296],"observed":[299],"10/31":[301],"(32%)":[302],"7/33":[308],"(21%)":[309,401],"Among":[313],"pts,":[315],"crossed":[322],"due":[324],"clinician-perceived":[326],"lack":[327],"despite":[330],"SCR.":[331],"occurred":[334],"(19%)":[337],"arm":[341],"(12%)":[344],"arm.":[348],"based":[350],"stringent":[352],"objective":[353],"physical":[356],"findings":[357],"seen":[359],"<35%":[361],"6-months":[363],"initial":[365],"either":[368],"CS,":[373],"but":[374],"<20%.":[378],"These":[379],"results":[380],"support":[381],"need":[383],"new":[385,438],"therapies":[386],"CS.Table.Initial":[388],"RandomizationImatinibRituximabN":[389],"randomized3537Patients":[390],"follow-up44Evaluable":[396],"patients3133Significant":[397],"response10":[399],"(32%)7":[400],"\u2022Treatment":[402],"success:":[403],"crossover,":[406],"relapse":[407],"death":[409],"months6":[412],"(19%)4":[413],"(12%)Treatment":[414],"failure":[415],"months26":[418],"(84%)29":[419],"(88%)":[420],"\u2022No":[421],"(SCR)*2024":[425],"\u2022Crossover":[426],"arm*2220":[430],"\u2022Relapse":[431],"death*37":[433],"Open":[434],"table":[435],"tab":[439]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}