{"id":"https://openalex.org/W2328635558","doi":"https://doi.org/10.1128/jvi.02898-15","title":"Development of Broadly Neutralizing Antibodies and Their Mapping by Monomeric gp120 in Human Immunodeficiency Virus Type 1-Infected Humans and Simian-Human Immunodeficiency Virus SHIV SF162P3N -Infected Macaques","display_name":"Development of Broadly Neutralizing Antibodies and Their Mapping by Monomeric gp120 in Human Immunodeficiency Virus Type 1-Infected Humans and Simian-Human Immunodeficiency Virus SHIV SF162P3N -Infected Macaques","publication_year":2016,"publication_date":"2016-02-04","ids":{"openalex":"https://openalex.org/W2328635558","doi":"https://doi.org/10.1128/jvi.02898-15","mag":"2328635558","pmid":"https://pubmed.ncbi.nlm.nih.gov/26842476","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4810546"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.02898-15","doi":"https://doi.org/10.1128/jvi.02898-15","is_oa":false,"landing_page_url":"https://jvi.asm.org/content/jvi/90/8/4017.full.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4810546","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112740386","display_name":"Manxue Jia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157122930","display_name":"Aaron Diamond AIDS Research Center","ror":"https://ror.org/04jdq2t93","country_code":"US","type":"facility","lineage":["https://openalex.org/I157122930"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manxue Jia","raw_affiliation_strings":["Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA","institution_ids":["https://openalex.org/I157122930","https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102290186","display_name":"Hong L\u00fc","orcid":"https://orcid.org/0000-0001-5593-6533","observed_orcids":["https://orcid.org/0000-0001-5593-6533"]},"institutions":[{"id":"https://openalex.org/I157122930","display_name":"Aaron Diamond AIDS Research Center","ror":"https://ror.org/04jdq2t93","country_code":"US","type":"facility","lineage":["https://openalex.org/I157122930"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hong Lu","raw_affiliation_strings":["Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA","institution_ids":["https://openalex.org/I157122930","https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065883600","display_name":"Martin H. Markowitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157122930","display_name":"Aaron Diamond AIDS Research Center","ror":"https://ror.org/04jdq2t93","country_code":"US","type":"facility","lineage":["https://openalex.org/I157122930"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Markowitz","raw_affiliation_strings":["Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA","institution_ids":["https://openalex.org/I157122930","https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056076181","display_name":"Cecilia Cheng\u2010Mayer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157122930","display_name":"Aaron Diamond AIDS Research Center","ror":"https://ror.org/04jdq2t93","country_code":"US","type":"facility","lineage":["https://openalex.org/I157122930"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cecilia Cheng-Mayer","raw_affiliation_strings":["Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA","institution_ids":["https://openalex.org/I157122930","https://openalex.org/I83399316"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089026508","display_name":"Xueling Wu","orcid":"https://orcid.org/0000-0002-9752-3734","observed_orcids":["https://orcid.org/0000-0002-9752-3734"]},"institutions":[{"id":"https://openalex.org/I157122930","display_name":"Aaron Diamond AIDS Research Center","ror":"https://ror.org/04jdq2t93","country_code":"US","type":"facility","lineage":["https://openalex.org/I157122930"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xueling Wu","raw_affiliation_strings":["Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, New York, New York, USA","institution_ids":["https://openalex.org/I157122930","https://openalex.org/I83399316"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.5354,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.89403581,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"90","issue":"8","first_page":"4017","last_page":"4031"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/broadly-neutralizing-antibodies","display_name":"broadly neutralizing antibodies","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.9559999704360962},{"id":"https://openalex.org/keywords/rhesus-macaques","display_name":"rhesus monkeys","score":0.9670000076293945},{"id":"https://openalex.org/keywords/cd4-binding-site","display_name":"CD4 binding site","score":0.8090000152587891},{"id":"https://openalex.org/keywords/v3-loop","display_name":"V3 loop","score":0.9879999756813049},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hiv-1-vaccine","display_name":"HIV-1 vaccine","score":0.6769999861717224},{"id":"https://openalex.org/keywords/antibody-development","display_name":"antibody development","score":0.3199999928474426},{"id":"https://openalex.org/keywords/cross-species-comparison","display_name":"cross-species comparison","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9004002809524536},{"id":"https://openalex.org/C2777995582","wikidata":"https://www.wikidata.org/wiki/Q1890246","display_name":"Simian immunodeficiency virus","level":3,"score":0.8886955380439758},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.8657435178756714},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.6147168278694153},{"id":"https://openalex.org/C2776488936","wikidata":"https://www.wikidata.org/wiki/Q5452918","display_name":"Simian","level":3,"score":0.6080245971679688},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5642058849334717},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5404613018035889},{"id":"https://openalex.org/C2779261636","wikidata":"https://www.wikidata.org/wiki/Q7003054","display_name":"Neutralizing antibody","level":3,"score":0.48805487155914307},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.4459529221057892},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.3207157850265503},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31231409311294556}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008253","descriptor_name":"Macaca mulatta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015302","descriptor_name":"Simian Immunodeficiency Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015335","descriptor_name":"Molecular Probes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015483","descriptor_name":"HIV Antibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015483","descriptor_name":"HIV Antibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015699","descriptor_name":"HIV Envelope Protein gp120","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016097","descriptor_name":"Simian Acquired Immunodeficiency Syndrome","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016097","descriptor_name":"Simian Acquired Immunodeficiency Syndrome","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018604","descriptor_name":"Epitope Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1128/jvi.02898-15","doi":"https://doi.org/10.1128/jvi.02898-15","is_oa":false,"landing_page_url":"https://jvi.asm.org/content/jvi/90/8/4017.full.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3991888","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4810546","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4810546","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4810546","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:26842476","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26842476","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3991888","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4810546","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8100000023841858,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1795550229","display_name":"Characterization and Generalization of a Novel Immunogenic Target on HIV-1 gp120","funder_award_id":"R21AI108399","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7477110137","display_name":"Deep Sequencing to Identify B-Cell Precursors of HIV-1 Neutralizing Antibodies","funder_award_id":"R01AI114380","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1505528250","https://openalex.org/W1533750546","https://openalex.org/W1937669064","https://openalex.org/W1963704583","https://openalex.org/W1974273518","https://openalex.org/W1977488202","https://openalex.org/W1978398372","https://openalex.org/W1991805858","https://openalex.org/W1997677784","https://openalex.org/W1998383398","https://openalex.org/W2001751895","https://openalex.org/W2002574877","https://openalex.org/W2003380951","https://openalex.org/W2006483986","https://openalex.org/W2009151161","https://openalex.org/W2010959676","https://openalex.org/W2011136801","https://openalex.org/W2019405644","https://openalex.org/W2025005245","https://openalex.org/W2029023023","https://openalex.org/W2029135056","https://openalex.org/W2029525307","https://openalex.org/W2040235378","https://openalex.org/W2042411186","https://openalex.org/W2049921779","https://openalex.org/W2059583074","https://openalex.org/W2075032293","https://openalex.org/W2083002978","https://openalex.org/W2084341498","https://openalex.org/W2093961711","https://openalex.org/W2095632120","https://openalex.org/W2097386513","https://openalex.org/W2103712192","https://openalex.org/W2103940273","https://openalex.org/W2105903892","https://openalex.org/W2107850607","https://openalex.org/W2108096886","https://openalex.org/W2110499527","https://openalex.org/W2110714233","https://openalex.org/W2112194489","https://openalex.org/W2112760617","https://openalex.org/W2113236498","https://openalex.org/W2116849917","https://openalex.org/W2116983636","https://openalex.org/W2118274231","https://openalex.org/W2121096721","https://openalex.org/W2122210861","https://openalex.org/W2122909018","https://openalex.org/W2124605791","https://openalex.org/W2128579789","https://openalex.org/W2133750999","https://openalex.org/W2135151522","https://openalex.org/W2137603774","https://openalex.org/W2144015945","https://openalex.org/W2146478787","https://openalex.org/W2146704167","https://openalex.org/W2148245437","https://openalex.org/W2150999673","https://openalex.org/W2152440860","https://openalex.org/W2156381249","https://openalex.org/W2156731171","https://openalex.org/W2162604485","https://openalex.org/W2164250779","https://openalex.org/W2164701456","https://openalex.org/W2166730438","https://openalex.org/W2168912344","https://openalex.org/W4235232179"],"related_works":["https://openalex.org/W2773531150","https://openalex.org/W2803953011","https://openalex.org/W2103147884","https://openalex.org/W3003365441","https://openalex.org/W2029023023","https://openalex.org/W1505528250","https://openalex.org/W2144015945","https://openalex.org/W3094063449","https://openalex.org/W1995033949","https://openalex.org/W2103038524"],"abstract_inverted_index":{"UNLABELLED:":[0],"To":[1],"improve":[2],"our":[3],"understanding":[4,247],"of":[5,33,46,74,86,105,121,127,144,160,206,230,237,250,301,326,329,371,385,392],"the":[6,31,99,147,154,193,196,199,203,212,228,248,302,316,321,330,337,342,346,367,383],"similarities":[7],"and":[8,21,96,124,172,202,214,264,272,278,353,369,381],"differences":[9],"between":[10,211,351],"neutralizing":[11,62,94,133,182,252],"antibodies":[12,63,164,253,334],"elicited":[13],"by":[14],"simian-human":[15],"immunodeficiency":[16,23],"virus":[17,24],"(SHIV)-infected":[18],"rhesus":[19,175,256],"macaques":[20,36,51,129,275,288,375],"human":[22,77,169,213,352],"type":[25],"1":[26,54,87],"(HIV-1)-infected":[27],"humans,":[28,284],"we":[29,267],"examined":[30,268],"plasma":[32,78,140],"13":[34,273],"viremic":[35],"infected":[37],"with":[38,43,60,98,114,142,307],"SHIVSF162P3Nand":[39],"85":[40,269],"HIV-1-infected":[41,270,283,379],"humans":[42,123,271,380],"known":[44],"times":[45],"infection.":[47],"We":[48],"identified":[49,117],"5":[50],"(38%)":[52],"from":[53,167,246],"to":[55,88,102,192,219,260,282,315,357,378],"2":[56,67,72,119,125,186],"years":[57,90,110],"postinfection":[58],"(p.i.)":[59],"broadly":[61,251],"(bnAbs)":[64,254],"against":[65,184],"tier":[66,185],"HIV-1.":[68],"In":[69,324],"comparison,":[70],"only":[71,118],"out":[73,104,120,126],"42":[75],"(5%)":[76],"samples":[79],"collected":[80],"in":[81,138,255,286,299,341,373,376],"a":[82,158,168,173],"similar":[83,281],"time":[84],"frame":[85],"3":[89,109],"p.i.":[91,111],"exhibited":[92],"comparable":[93],"breadths":[95],"potencies,":[97],"number":[100],"increasing":[101],"7":[103],"21":[106],"(30%)":[107],"after":[108],"Plasma":[112,305],"mapping":[113,306],"monomeric":[115,308],"gp120":[116,155,309,322],"9":[122],"4":[128],"that":[130,311],"contained":[131],"gp120-reactive":[132,332],"antibodies,":[134],"indicating":[135],"distinct":[136],"specificities":[137],"these":[139],"samples,":[141],"most":[143,312],"them":[145],"recognizing":[146],"envelope":[148,231,317,386],"trimer":[149,232,318,387],"(including":[150],"gp41)":[151],"rather":[152,319],"than":[153,320],"monomer.":[156,323],"Indeed,":[157],"total":[159],"20":[161],"gp120-directed":[162],"monoclonal":[163,333],"(MAbs)":[165,335],"isolated":[166,189,331],"subject":[170],"(AD358)":[171],"Chinese":[174],"macaque":[176,215,354],"(GB40)":[177],"displayed":[178,336],"no":[179],"or":[180],"limited":[181],"activity":[183],"strains.":[187],"These":[188,224],"MAbs,":[190],"mapped":[191],"CD4-binding":[194],"site,":[195],"V3":[197],"loop,":[198],"inner":[200],"domain,":[201],"C5":[204],"region":[205],"gp120,":[207],"revealed":[208,349],"genetic":[209],"similarity":[210,350],"immunoglobulin":[216],"genes":[217,355],"used":[218,259,356],"encode":[220,358],"some":[221,300,359],"V3-directed":[222,360],"MAbs.":[223,361],"results":[225],"also":[226,290],"support":[227,325],"use":[229,384],"probes":[233,388],"for":[234,276,389],"efficient":[235,390],"isolation":[236],"HIV-1":[238,241],"bnAbs.":[239,393],"IMPORTANCE:":[240],"vaccine":[242,262],"research":[243],"can":[244],"benefit":[245],"development":[249,294,370],"macaques,":[257],"commonly":[258],"assess":[261],"immunogenicity":[263],"efficacy.":[265],"Here,":[266],"SHIVSF162P3N-infected":[274],"bnAbs":[277,285,313,372],"found":[279],"that,":[280],"SHIV-infected":[287,374],"are":[289],"rare,":[291],"but":[292],"their":[293],"might":[295],"have":[296],"been":[297],"faster":[298],"studied":[303],"macaques.":[304],"indicated":[310],"bind":[314],"this,":[327],"none":[328],"neutralization":[338],"breadth":[339],"observed":[340],"corresponding":[343],"plasma.":[344],"However,":[345],"MAb":[347],"sequences":[348],"Our":[362],"study":[363],"sheds":[364],"light":[365],"on":[366],"timing":[368],"comparison":[377],"highlights":[382],"recovery":[391]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}