{"id":"https://openalex.org/W2326649554","doi":"https://doi.org/10.1016/j.jalz.2013.04.454","title":"F5\u201301\u201304: Subjective cognitive concerns as an early indicator of Alzheimer's disease pathology","display_name":"F5\u201301\u201304: Subjective cognitive concerns as an early indicator of Alzheimer's disease pathology","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W2326649554","doi":"https://doi.org/10.1016/j.jalz.2013.04.454","mag":"2326649554"},"language":"en","primary_location":{"id":"doi:10.1016/j.jalz.2013.04.454","doi":"https://doi.org/10.1016/j.jalz.2013.04.454","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jalz.2013.04.454","pdf_url":null,"source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084568106","display_name":"Rebecca England Amariglio","orcid":"https://orcid.org/0009-0009-5878-8930","observed_orcids":["https://orcid.org/0009-0009-5878-8930"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rebecca Amariglio","raw_affiliation_strings":["Massachusetts General Hospital, Boston, Massachusetts, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Boston, Massachusetts, United States","institution_ids":["https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5084568106"],"corresponding_institution_ids":["https://openalex.org/I4210087915"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":0.2358,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65552208,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"9","issue":"4S_Part_21","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subjective-cognitive-concerns","display_name":"subjective cognitive concerns","score":0.9750000238418579},{"id":"https://openalex.org/keywords/preclinical-alzheimer-s-disease","display_name":"preclinical Alzheimer's disease","score":0.9120000004768372}],"concepts":[{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6769294738769531},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.45103439688682556},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4360497295856476},{"id":"https://openalex.org/C3017833866","wikidata":"https://www.wikidata.org/wiki/Q2397106","display_name":"Tau pathology","level":4,"score":0.4296118915081024},{"id":"https://openalex.org/C67739388","wikidata":"https://www.wikidata.org/wiki/Q579471","display_name":"Cognitive reserve","level":4,"score":0.4250723719596863},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4217739403247833},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.38300424814224243},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.3830028772354126},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.351323664188385},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.21511057019233704}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jalz.2013.04.454","doi":"https://doi.org/10.1016/j.jalz.2013.04.454","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jalz.2013.04.454","pdf_url":null,"source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1995779519","https://openalex.org/W2111382765","https://openalex.org/W4245784704","https://openalex.org/W2889724547","https://openalex.org/W2142904655","https://openalex.org/W7006130583","https://openalex.org/W2532820602","https://openalex.org/W2911758536","https://openalex.org/W1998355082","https://openalex.org/W2531328373"],"abstract_inverted_index":{"Although":[0],"self-reported":[1],"cognitive":[2,27,186,252],"concerns":[3],"(SCC)":[4],"have":[5,88,139,168],"previously":[6],"been":[7,130],"dismissed":[8],"as":[9,133,135],"a":[10,141,173,249,259],"sign":[11],"of":[12,32,69,179,218,223,237,251,268,300],"the":[13,30,115,224,235,297],"\u201cworried":[14],"well\u201d,":[15],"there":[16],"is":[17],"emerging":[18],"evidence":[19,68,82,210],"to":[20,57,161,167,232,240,258,277],"suggest":[21],"that":[22,47,105,183,247,254,291],"SCC":[23,49,78,106,128,145,212,227,246],"may":[24,50,64,107,213,271],"herald":[25],"initial":[26],"decrements":[28],"at":[29,296],"stage":[31,299],"preclinical":[33,298],"Alzheimer's":[34],"disease":[35],"(AD).":[36],"Recent":[37],"preliminary":[38],"data":[39],"from":[40],"our":[41],"own":[42],"group":[43,261],"and":[44,63,96,101,127,146,190,228],"others":[45],"suggests":[46,211],"specific":[48],"in":[51,83,99,150,274],"fact":[52],"indicate":[53],"early":[54,70,110,216,278],"awareness":[55],"prior":[56],"objective":[58],"impairment":[59],"on":[60,72,181,234],"standardized":[61],"tests":[62],"be":[65,214,272,293],"associated":[66,194,204],"with":[67,79,109,195,205,266],"pathology":[71],"AD":[73,80,219,279],"biomarkers.":[74],"Multimodality":[75],"studies":[76],"relating":[77],"biomarker":[81],"clinically":[84],"normal":[85],"(CN)":[86],"individuals":[87,155],"revealed":[89],"associations":[90],"between":[91,117,144,175,226],"decreased":[92],"gray":[93],"matter":[94],"volume":[95],"cerebral":[97],"hypometabolism":[98],"parietotemporal":[100],"parahippocampal":[102],"regions,":[103],"suggesting":[104],"coincide":[108],"pathological":[111],"changes.":[112,243],"More":[113],"recently,":[114],"relationship":[116,143,174,225],"A":[118],"b":[119],"burden,":[120],"using":[121],"11":[122],"C":[123],"PiB-PET":[124],"amyloid":[125,196,229],"imaging,":[126],"has":[129],"investigated.":[131],"We,":[132],"well":[134],"another":[136],"research":[137],"group,":[138],"reported":[140,157],"significant":[142],"cortical":[147],"PiB":[148,170,207],"binding":[149],"CN":[151],"individuals.":[152],"In":[153],"particular,":[154],"who":[156],"worse":[158],"memory":[159],"relative":[160,257],"their":[162],"peers":[163],"were":[164],"more":[165],"likely":[166],"increased":[169,206],"retention.":[171],"Additionally,":[172],"an":[176,215],"individual's":[177],"self-report":[178],"decline":[180],"tasks":[182],"required":[184],"higher-level":[185],"processing":[187],"(i.e.,":[188],"prioritizing":[189],"organizing":[191],"tasks)":[192],"was":[193,202],"burden.":[197],"By":[198],"contrast,":[199],"informant":[200],"report":[201],"not":[203],"binding.":[208],"Accumulating":[209],"indicator":[217],"pathology.":[220,280],"The":[221],"strength":[222],"burden":[230],"appears":[231],"depend":[233],"types":[236],"questions":[238],"used":[239],"assess":[241],"subjective":[242],"Going":[244],"forward,":[245],"probe":[248],"range":[250],"functions":[253],"are":[255],"framed":[256],"reference":[260],"(self":[262],"and/or":[263],"age-matched":[264],"peers)":[265],"consideration":[267],"temporal":[269],"course":[270],"important":[273],"understanding":[275],"relationships":[276],"Findings":[281],"will":[282,292],"provide":[283],"critical":[284],"information":[285],"for":[286],"future":[287],"secondary":[288],"prevention":[289],"trials":[290],"seeking":[294],"subjects":[295],"AD.":[301]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}