{"id":"https://openalex.org/W2325904644","doi":"https://doi.org/10.1016/j.smim.2016.03.018","title":"Human neutrophils: Their role in cancer and relation to myeloid-derived suppressor cells","display_name":"Human neutrophils: Their role in cancer and relation to myeloid-derived suppressor cells","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W2325904644","doi":"https://doi.org/10.1016/j.smim.2016.03.018","mag":"2325904644","pmid":"https://pubmed.ncbi.nlm.nih.gov/27067179"},"language":"en","primary_location":{"id":"doi:10.1016/j.smim.2016.03.018","doi":"https://doi.org/10.1016/j.smim.2016.03.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.smim.2016.03.018","pdf_url":null,"source":{"id":"https://openalex.org/S161731549","display_name":"Seminars in Immunology","issn_l":"1044-5323","issn":["1044-5323","1096-3618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Immunology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2325904644"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073438747","display_name":"Katrin Moses","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210119759"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katrin Moses","raw_affiliation_strings":["Research Division of the Department of Otorhinolaryngology, University Hospital Essen, West German Cancer Center, German Cancer Consortium, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Division of the Department of Otorhinolaryngology, University Hospital Essen, West German Cancer Center, German Cancer Consortium, Germany","institution_ids":["https://openalex.org/I4210119759"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003700004","display_name":"Sven Brandau","orcid":"https://orcid.org/0000-0002-2702-4163","observed_orcids":["https://orcid.org/0000-0002-2702-4163","https://orcid.org/0000-0001-8853-5111"]},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210119759"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Sven Brandau","raw_affiliation_strings":["Research Division of the Department of Otorhinolaryngology, University Hospital Essen, West German Cancer Center, German Cancer Consortium, Germany. Electronic address: Sven.Brandau@uk-essen.de","Research Division of the Department of Otorhinolaryngology, University Hospital Essen, West German Cancer Center, German Cancer Consortium, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Division of the Department of Otorhinolaryngology, University Hospital Essen, West German Cancer Center, German Cancer Consortium, Germany. Electronic address: Sven.Brandau@uk-essen.de","institution_ids":["https://openalex.org/I4210119759"]},{"raw_affiliation_string":"Research Division of the Department of Otorhinolaryngology, University Hospital Essen, West German Cancer Center, German Cancer Consortium, Germany","institution_ids":["https://openalex.org/I4210119759"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003700004"],"corresponding_institution_ids":["https://openalex.org/I4210119759"],"apc_list":{"value":4370,"currency":"USD","value_usd":4370},"apc_paid":null,"fwci":2.9212,"has_fulltext":false,"cited_by_count":319,"citation_normalized_percentile":{"value":0.94382487,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"28","issue":"2","first_page":"187","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.9509999752044678},{"id":"https://openalex.org/keywords/tumor-associated-neutrophils","display_name":"tumor-associated neutrophils","score":0.921999990940094},{"id":"https://openalex.org/keywords/myeloid-derived-suppressor-cells","display_name":"myeloid-derived suppressor cells","score":0.968999981880188},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.796999990940094},{"id":"https://openalex.org/keywords/neutrophil-to-lymphocyte-ratio","display_name":"neutrophil-to-lymphocyte ratio","score":0.9879999756813049},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8460000157356262},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.859000027179718},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.8650000095367432},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.746999979019165},{"id":"https://openalex.org/keywords/neutrophil-targeted-therapy","display_name":"neutrophil-targeted therapy","score":0.7839999794960022},{"id":"https://openalex.org/keywords/pmn-mdscs","display_name":"polymorphonuclear myeloid-derived suppressor cells","score":0.8339999914169312}],"concepts":[{"id":"https://openalex.org/C55721878","wikidata":"https://www.wikidata.org/wiki/Q15220362","display_name":"Myeloid-derived Suppressor Cell","level":4,"score":0.7226971387863159},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.5930862426757812},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5468092560768127},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5242189168930054},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.5142195224761963},{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.50081467628479},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.4952830374240875},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.47904908657073975},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4638078212738037},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.43950724601745605},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.43912410736083984},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4243125319480896},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.41848501563072205},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3829864263534546},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.37032634019851685},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.25113728642463684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12999606132507324},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072737","descriptor_name":"Myeloid-Derived Suppressor Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000072737","descriptor_name":"Myeloid-Derived Suppressor Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004198","descriptor_name":"Disease Susceptibility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018375","descriptor_name":"Neutrophil Activation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020556","descriptor_name":"Neutrophil Infiltration","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D056747","descriptor_name":"Immunomodulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.smim.2016.03.018","doi":"https://doi.org/10.1016/j.smim.2016.03.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.smim.2016.03.018","pdf_url":null,"source":{"id":"https://openalex.org/S161731549","display_name":"Seminars in Immunology","issn_l":"1044-5323","issn":["1044-5323","1096-3618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Immunology","raw_type":"journal-article"},{"id":"pmid:27067179","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27067179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3890785568","display_name":null,"funder_award_id":"BM1404","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":126,"referenced_works":["https://openalex.org/W71124682","https://openalex.org/W293548796","https://openalex.org/W795307168","https://openalex.org/W1107917109","https://openalex.org/W1476833121","https://openalex.org/W1508738699","https://openalex.org/W1546909751","https://openalex.org/W1564398196","https://openalex.org/W1577847722","https://openalex.org/W1595547013","https://openalex.org/W1820144252","https://openalex.org/W1834481809","https://openalex.org/W1847993443","https://openalex.org/W1872017712","https://openalex.org/W1903025975","https://openalex.org/W1925817305","https://openalex.org/W1926597952","https://openalex.org/W1964819072","https://openalex.org/W1974713508","https://openalex.org/W1976965953","https://openalex.org/W1978346387","https://openalex.org/W1978866729","https://openalex.org/W1980029123","https://openalex.org/W1982159979","https://openalex.org/W1985130705","https://openalex.org/W1989111278","https://openalex.org/W1989889358","https://openalex.org/W1991365889","https://openalex.org/W1991947126","https://openalex.org/W1993281827","https://openalex.org/W2000756990","https://openalex.org/W2001378959","https://openalex.org/W2002157461","https://openalex.org/W2003268223","https://openalex.org/W2006474456","https://openalex.org/W2008658155","https://openalex.org/W2009880267","https://openalex.org/W2010391415","https://openalex.org/W2013774061","https://openalex.org/W2014466662","https://openalex.org/W2019010677","https://openalex.org/W2019172298","https://openalex.org/W2020912886","https://openalex.org/W2022512688","https://openalex.org/W2028710588","https://openalex.org/W2030711913","https://openalex.org/W2031868265","https://openalex.org/W2035110681","https://openalex.org/W2035267126","https://openalex.org/W2036965973","https://openalex.org/W2038918212","https://openalex.org/W2042846292","https://openalex.org/W2046749412","https://openalex.org/W2050975242","https://openalex.org/W2054246680","https://openalex.org/W2056063027","https://openalex.org/W2062425552","https://openalex.org/W2062627337","https://openalex.org/W2067931754","https://openalex.org/W2068934982","https://openalex.org/W2068994108","https://openalex.org/W2070818071","https://openalex.org/W2070968699","https://openalex.org/W2072706091","https://openalex.org/W2074898491","https://openalex.org/W2079301298","https://openalex.org/W2080631077","https://openalex.org/W2082413924","https://openalex.org/W2082493329","https://openalex.org/W2086602355","https://openalex.org/W2088067478","https://openalex.org/W2088329704","https://openalex.org/W2089880886","https://openalex.org/W2090488685","https://openalex.org/W2095914632","https://openalex.org/W2109930846","https://openalex.org/W2113737833","https://openalex.org/W2115658806","https://openalex.org/W2117225762","https://openalex.org/W2117728670","https://openalex.org/W2131845821","https://openalex.org/W2132132140","https://openalex.org/W2137413455","https://openalex.org/W2138419579","https://openalex.org/W2139731402","https://openalex.org/W2139806485","https://openalex.org/W2141186092","https://openalex.org/W2141403707","https://openalex.org/W2152514732","https://openalex.org/W2155440695","https://openalex.org/W2156971530","https://openalex.org/W2157096396","https://openalex.org/W2157865597","https://openalex.org/W2158809810","https://openalex.org/W2161567108","https://openalex.org/W2163581770","https://openalex.org/W2167293792","https://openalex.org/W2168205651","https://openalex.org/W2171524684","https://openalex.org/W2175766278","https://openalex.org/W2186246196","https://openalex.org/W2204314766","https://openalex.org/W2208644914","https://openalex.org/W2211944491","https://openalex.org/W2214799754","https://openalex.org/W2215578332","https://openalex.org/W2216468827","https://openalex.org/W2220762972","https://openalex.org/W2230023079","https://openalex.org/W2237361742","https://openalex.org/W2239871737","https://openalex.org/W2246837493","https://openalex.org/W2256822698","https://openalex.org/W2270004474","https://openalex.org/W2276764162","https://openalex.org/W2282098123","https://openalex.org/W2292022254","https://openalex.org/W2299857908","https://openalex.org/W2317575649","https://openalex.org/W2318762303","https://openalex.org/W2328637902","https://openalex.org/W2346381417","https://openalex.org/W2411042699","https://openalex.org/W2413014308","https://openalex.org/W2471500324","https://openalex.org/W6628740653"],"related_works":["https://openalex.org/W357490084","https://openalex.org/W3084588093","https://openalex.org/W3025031510","https://openalex.org/W3017788359","https://openalex.org/W2155360682","https://openalex.org/W4313575723","https://openalex.org/W2981524284","https://openalex.org/W4313374728","https://openalex.org/W2806058593","https://openalex.org/W4410980498"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":32},{"year":2022,"cited_by_count":38},{"year":2021,"cited_by_count":46},{"year":2020,"cited_by_count":49},{"year":2019,"cited_by_count":25},{"year":2018,"cited_by_count":33},{"year":2017,"cited_by_count":29},{"year":2016,"cited_by_count":8}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}
