{"id":"https://openalex.org/W2325728323","doi":"https://doi.org/10.4052/tigg.16.305","title":"Chemical Tools for the Study of Polysialic Acid","display_name":"Chemical Tools for the Study of Polysialic Acid","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2325728323","doi":"https://doi.org/10.4052/tigg.16.305","mag":"2325728323"},"language":"en","primary_location":{"id":"doi:10.4052/tigg.16.305","doi":"https://doi.org/10.4052/tigg.16.305","is_oa":true,"landing_page_url":"https://doi.org/10.4052/tigg.16.305","pdf_url":"https://www.jstage.jst.go.jp/article/tigg1989/16/91/16_91_305/_pdf","source":{"id":"https://openalex.org/S177382209","display_name":"Trends in Glycoscience and Glycotechnology","issn_l":"0915-7352","issn":["0915-7352","1883-2113"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4362726045","host_organization_name":"Forum: Carbohydrate Coming of Age (FCCA)","host_organization_lineage":["https://openalex.org/P4362726045"],"host_organization_lineage_names":["Forum: Carbohydrate Coming of Age (FCCA)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Glycoscience and Glycotechnology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/tigg1989/16/91/16_91_305/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005924526","display_name":"Jomy Samuel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jomy Samuel","raw_affiliation_strings":["The Department of Chemistry the Howard Hughes Medical Institute, University of California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Chemistry the Howard Hughes Medical Institute, University of California","institution_ids":["https://openalex.org/I1344073410"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088409133","display_name":"Carolyn Ruth Bertozzi","orcid":"https://orcid.org/0000-0003-4482-2754","observed_orcids":["https://orcid.org/0000-0003-4482-2754"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carolyn R. Bertozzi","raw_affiliation_strings":["Center for Advanced Materials, Materials Science Division, Lawrence Berkeley National Laboratory","The Department of Cell Biology the Howard Hughes Medical Institute, University of California","The Department of Chemistry the Howard Hughes Medical Institute, University of California","The Department of Molecular, the Howard Hughes Medical Institute, University of California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Advanced Materials, Materials Science Division, Lawrence Berkeley National Laboratory","institution_ids":["https://openalex.org/I148283060"]},{"raw_affiliation_string":"The Department of Cell Biology the Howard Hughes Medical Institute, University of California","institution_ids":["https://openalex.org/I1344073410"]},{"raw_affiliation_string":"The Department of Chemistry the Howard Hughes Medical Institute, University of California","institution_ids":["https://openalex.org/I1344073410"]},{"raw_affiliation_string":"The Department of Molecular, the Howard Hughes Medical Institute, University of California","institution_ids":["https://openalex.org/I1344073410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1183,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.47412923,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"16","issue":"91","first_page":"305","last_page":"318"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.573199987411499,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.573199987411499,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.42329999804496765,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11440","display_name":"Click Chemistry and Applications","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polysialic-acid","display_name":"polysialic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sialic-acid-analogs","display_name":"sialic acid analogues","score":0.8149999976158142},{"id":"https://openalex.org/keywords/neisseria-meningitidis-serogroup-b","display_name":"Neisseria meningitidis serogroup B","score":0.8190000057220459},{"id":"https://openalex.org/keywords/meningitis","display_name":"meningitis","score":0.6110000014305115},{"id":"https://openalex.org/keywords/neural-development","display_name":"neural development","score":0.6629999876022339},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C2778993516","wikidata":"https://www.wikidata.org/wiki/Q7226934","display_name":"Polysialic acid","level":5,"score":0.9935018420219421},{"id":"https://openalex.org/C2778458888","wikidata":"https://www.wikidata.org/wiki/Q154625","display_name":"Neisseria meningitidis","level":3,"score":0.6654587388038635},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6039429903030396},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5336196422576904},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3471142649650574},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3138398230075836},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.233900249004364},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.22258293628692627},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.08680844306945801},{"id":"https://openalex.org/C122871604","wikidata":"https://www.wikidata.org/wiki/Q2248886","display_name":"Neural cell adhesion molecule","level":4,"score":0.08450332283973694},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08154669404029846},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.0},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4052/tigg.16.305","doi":"https://doi.org/10.4052/tigg.16.305","is_oa":true,"landing_page_url":"https://doi.org/10.4052/tigg.16.305","pdf_url":"https://www.jstage.jst.go.jp/article/tigg1989/16/91/16_91_305/_pdf","source":{"id":"https://openalex.org/S177382209","display_name":"Trends in Glycoscience and Glycotechnology","issn_l":"0915-7352","issn":["0915-7352","1883-2113"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4362726045","host_organization_name":"Forum: Carbohydrate Coming of Age (FCCA)","host_organization_lineage":["https://openalex.org/P4362726045"],"host_organization_lineage_names":["Forum: Carbohydrate Coming of Age (FCCA)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Glycoscience and Glycotechnology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4052/tigg.16.305","doi":"https://doi.org/10.4052/tigg.16.305","is_oa":true,"landing_page_url":"https://doi.org/10.4052/tigg.16.305","pdf_url":"https://www.jstage.jst.go.jp/article/tigg1989/16/91/16_91_305/_pdf","source":{"id":"https://openalex.org/S177382209","display_name":"Trends in Glycoscience and Glycotechnology","issn_l":"0915-7352","issn":["0915-7352","1883-2113"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4362726045","host_organization_name":"Forum: Carbohydrate Coming of Age (FCCA)","host_organization_lineage":["https://openalex.org/P4362726045"],"host_organization_lineage_names":["Forum: Carbohydrate Coming of Age (FCCA)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Glycoscience and Glycotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2325728323.pdf","grobid_xml":"https://content.openalex.org/works/W2325728323.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W130077425","https://openalex.org/W609107377","https://openalex.org/W1491995663","https://openalex.org/W1898190883","https://openalex.org/W1986147894","https://openalex.org/W2043051084","https://openalex.org/W2070100963","https://openalex.org/W2073836203","https://openalex.org/W2116001176","https://openalex.org/W2125716220","https://openalex.org/W2126456750","https://openalex.org/W2155812349","https://openalex.org/W6601277159","https://openalex.org/W6601475091","https://openalex.org/W6602861011","https://openalex.org/W6604240834","https://openalex.org/W6618310308","https://openalex.org/W6725633066","https://openalex.org/W6832416156"],"related_works":["https://openalex.org/W4365792184","https://openalex.org/W2946514583","https://openalex.org/W2892732901","https://openalex.org/W2023929116","https://openalex.org/W2503383838","https://openalex.org/W4313593885","https://openalex.org/W3082926360","https://openalex.org/W2147212856","https://openalex.org/W2083183265","https://openalex.org/W136392505"],"abstract_inverted_index":{"\u30dd\u30ea\u30b7\u30a2\u30eb\u9178":[0],"(PSA)":[1],"\u306f\u3001\u591a\u6a5f\u80fd\u30d0\u30a4\u30aa\u30dd\u30ea\u30de\u30fc\u3067\u3042\u308b\u3002PSA\u306f\u9ad8\u7b49\u306a\u7121\u810a\u690e\u52d5\u7269\u3084\u810a\u690e\u52d5\u7269\u306a\u3069\u306e\u771f\u6838\u751f\u7269\u3001\u304a\u3088\u3073\u3001\u795e\u7d4c\u4fb5\u8972\u6027\u7d30\u83cc\u3067\u3042\u308b":[2],"Neisseria":[3],"meningitidis":[4],"B\u306e\u3088\u3046\u306a\u539f\u6838\u751f\u7269\u306a\u3069\u3001\u5e83\u3044\u7bc4\u56f2\u306b\u308f\u305f\u3063\u3066\u691c\u51fa\u3055\u308c\u308b\u3002\u54fa\u4e73\u985e\u306b\u304a\u3044\u3066\u3001PSA\u306e\u767a\u73fe\u306f\u767a\u751f\u904e\u7a0b\u306b\u3088\u308a\u5236\u5fa1\u3055\u308c\u3001\u795e\u7d4c\u767a\u751f\u3001\u304a\u3088\u3073\u3001\u7d30\u80de\u306e\u764c\u5316\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3002\u7d30\u83cc\u306b\u304a\u3044\u3066\u306f\u3001PSA\u306f\u6bd2\u6027\u306e\u539f\u56e0\u3068\u306a\u308b\u3002\u5206\u5149\u5b66\u7684\u624b\u6cd5\u3068\u514d\u75ab\u5b66\u7684\u5206\u6790\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001PSA\u306e\u69cb\u9020\u3068\u3001\u305d\u306e\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u306e\u95a2\u9023\u6027\u306b\u5bfe\u3059\u308b\u7406\u89e3\u304c\u975e\u5e38\u306b\u6df1\u307e\u3063\u305f\u3002\u5929\u7136\u306b\u306f\u5b58\u5728\u3057\u306a\u3044\u30b7\u30a2\u30eb\u9178\u985e\u4f3c\u4f53\u3092\u542b\u3081\u305f\u5316\u5b66\u7684\u624b\u6cd5\u306e\u5229\u7528\u306f\u3001\u57f9\u990a\u7d30\u80de\u3001\u3082\u3057\u304f\u306f\u3001in":[5],"vivo":[6],"\u306b\u304a\u3044\u3066\u3001PSA\u767a\u73fe\u306e\u8abf\u7bc0\u3092\u5bb9\u6613\u306b\u3057\u305f\u3002\u975e\u5929\u7136\u578b\u30b7\u30a2\u30eb\u9178\u306e\u5229\u7528\u304c\u3001\u9ac4\u819c\u708e\u83cc\u3001\u3055\u3089\u306b\u3001\u764c\u306b\u5bfe\u3059\u308b\u30ef\u30af\u30c1\u30f3\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u3063\u305f\u3002":[7]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}