{"id":"https://openalex.org/W2325650814","doi":"https://doi.org/10.1158/1940-6207.capr-14-0311","title":"Immunoprevention of Human Papillomavirus\u2013Associated Malignancies","display_name":"Immunoprevention of Human Papillomavirus\u2013Associated Malignancies","publication_year":2014,"publication_date":"2014-12-09","ids":{"openalex":"https://openalex.org/W2325650814","doi":"https://doi.org/10.1158/1940-6207.capr-14-0311","mag":"2325650814","pmid":"https://pubmed.ncbi.nlm.nih.gov/25488410","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4315720"},"language":"en","primary_location":{"id":"doi:10.1158/1940-6207.capr-14-0311","doi":"https://doi.org/10.1158/1940-6207.capr-14-0311","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1940-6207.capr-14-0311","pdf_url":null,"source":{"id":"https://openalex.org/S68240649","display_name":"Cancer Prevention Research","issn_l":"1940-6207","issn":["1940-6207","1940-6215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Prevention Research","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4315720","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075860092","display_name":"Joshua W. Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua W. Wang","raw_affiliation_strings":["1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chein-fu Hung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chein-fu Hung","raw_affiliation_strings":["1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076400654","display_name":"Warner King Huh","orcid":"https://orcid.org/0000-0003-2881-9846","observed_orcids":["https://orcid.org/0000-0003-2881-9846"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Warner K. Huh","raw_affiliation_strings":["2Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043851739","display_name":"Cornelia Liu Trimble","orcid":"https://orcid.org/0000-0003-0397-5295","observed_orcids":["https://orcid.org/0000-0003-0397-5295"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cornelia L. Trimble","raw_affiliation_strings":["1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland","3Department of Oncology, The Johns Hopkins University, Baltimore, Maryland","4Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"3Department of Oncology, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"4Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089035026","display_name":"Richard B. S. Roden","orcid":"https://orcid.org/0000-0002-2506-0195","observed_orcids":["https://orcid.org/0000-0002-2506-0195"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Richard B.S. Roden","raw_affiliation_strings":["1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland","3Department of Oncology, The Johns Hopkins University, Baltimore, Maryland","4Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pathology, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"3Department of Oncology, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"4Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5089035026"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":null,"apc_paid":null,"fwci":0.8295,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.60674982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"8","issue":"2","first_page":"95","last_page":"104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-papillomavirus","display_name":"human papillomavirus","score":0.9810000061988831},{"id":"https://openalex.org/keywords/hpv-associated-cancers","display_name":"HPV-associated cancers","score":0.7459999918937683},{"id":"https://openalex.org/keywords/hpv-vaccination","display_name":"HPV vaccination","score":0.6359999775886536},{"id":"https://openalex.org/keywords/virus-like-particles","display_name":"virus-like particles","score":0.7910000085830688},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"cervical cancer","score":0.7179999947547913},{"id":"https://openalex.org/keywords/cervical-intraepithelial-neoplasia","display_name":"cervical intraepithelial neoplasia","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cervical-cancer-screening","display_name":"cervical cancer screening","score":0.722000002861023},{"id":"https://openalex.org/keywords/pap-test","display_name":"Pap smear","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hpv-testing","display_name":"HPV testing","score":0.6740000247955322},{"id":"https://openalex.org/keywords/immunoprevention","display_name":"immunoprevention","score":0.7599999904632568},{"id":"https://openalex.org/keywords/vaccine-cost-reduction","display_name":"vaccine cost reduction","score":0.593999981880188},{"id":"https://openalex.org/keywords/developing-countries","display_name":"developing countries","score":0.5699999928474426},{"id":"https://openalex.org/keywords/high-risk-hpv-genotypes","display_name":"high-risk HPV genotypes","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.751838207244873},{"id":"https://openalex.org/C2780009117","wikidata":"https://www.wikidata.org/wiki/Q900189","display_name":"HPV vaccines","level":5,"score":0.666404128074646},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.6599192023277283},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6212723255157471},{"id":"https://openalex.org/C65051434","wikidata":"https://www.wikidata.org/wiki/Q3123079","display_name":"Papanicolaou stain","level":4,"score":0.5658170580863953},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5033549666404724},{"id":"https://openalex.org/C2780234812","wikidata":"https://www.wikidata.org/wiki/Q1787013","display_name":"Cancer prevention","level":3,"score":0.4980754852294922},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49261265993118286},{"id":"https://openalex.org/C2777343196","wikidata":"https://www.wikidata.org/wiki/Q196788","display_name":"Cervical intraepithelial neoplasia","level":4,"score":0.47211897373199463},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4513987898826599},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41818705201148987},{"id":"https://openalex.org/C2778580637","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"HPV infection","level":4,"score":0.389883816242218},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3898792862892151}],"mesh":[{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D053918","descriptor_name":"Papillomavirus Vaccines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1158/1940-6207.capr-14-0311","doi":"https://doi.org/10.1158/1940-6207.capr-14-0311","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1940-6207.capr-14-0311","pdf_url":null,"source":{"id":"https://openalex.org/S68240649","display_name":"Cancer Prevention Research","issn_l":"1940-6207","issn":["1940-6207","1940-6215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Prevention Research","raw_type":"journal-article"},{"id":"pmid:25488410","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25488410","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer prevention research (Philadelphia, Pa.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4315720","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4315720","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer Prev Res (Phila)","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4315720","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4315720","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer Prev Res (Phila)","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1850197143","display_name":"A Phase I Study to Evaluate the Safety and Immunogenicity of HPV 16 L2 11-200","funder_award_id":"R01CA133749","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2370794842","display_name":"Mechanisms of Papillomavirus Neutralization","funder_award_id":"R01CA118790","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000866064","display_name":"SPORE in Cervical Cancer","funder_award_id":"P50CA098252","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":126,"referenced_works":["https://openalex.org/W580625913","https://openalex.org/W1523933945","https://openalex.org/W1722478811","https://openalex.org/W1831319429","https://openalex.org/W1846731397","https://openalex.org/W1876505025","https://openalex.org/W1932265838","https://openalex.org/W1953738657","https://openalex.org/W1967960141","https://openalex.org/W1976051908","https://openalex.org/W1980750660","https://openalex.org/W1983853879","https://openalex.org/W1984619729","https://openalex.org/W1986310806","https://openalex.org/W1987350137","https://openalex.org/W1990555336","https://openalex.org/W1993945172","https://openalex.org/W1994419043","https://openalex.org/W1999882243","https://openalex.org/W2000825155","https://openalex.org/W2007245430","https://openalex.org/W2007816485","https://openalex.org/W2011562475","https://openalex.org/W2013513561","https://openalex.org/W2014164721","https://openalex.org/W2017096286","https://openalex.org/W2017558201","https://openalex.org/W2033546933","https://openalex.org/W2035303184","https://openalex.org/W2037942645","https://openalex.org/W2038315892","https://openalex.org/W2038748174","https://openalex.org/W2039745983","https://openalex.org/W2039899610","https://openalex.org/W2039912137","https://openalex.org/W2040927104","https://openalex.org/W2043223046","https://openalex.org/W2045403138","https://openalex.org/W2046182783","https://openalex.org/W2046520115","https://openalex.org/W2049272060","https://openalex.org/W2052874737","https://openalex.org/W2055447440","https://openalex.org/W2057706962","https://openalex.org/W2058244483","https://openalex.org/W2064273388","https://openalex.org/W2066671159","https://openalex.org/W2067415595","https://openalex.org/W2069143946","https://openalex.org/W2069355167","https://openalex.org/W2069794080","https://openalex.org/W2070264917","https://openalex.org/W2071606440","https://openalex.org/W2071686791","https://openalex.org/W2072629032","https://openalex.org/W2073231427","https://openalex.org/W2074393293","https://openalex.org/W2078484577","https://openalex.org/W2078947642","https://openalex.org/W2082410121","https://openalex.org/W2084982248","https://openalex.org/W2086463570","https://openalex.org/W2089569798","https://openalex.org/W2089720244","https://openalex.org/W2090426026","https://openalex.org/W2093480157","https://openalex.org/W2095127577","https://openalex.org/W2095903414","https://openalex.org/W2096023567","https://openalex.org/W2096866753","https://openalex.org/W2097648465","https://openalex.org/W2101196984","https://openalex.org/W2103744532","https://openalex.org/W2107415042","https://openalex.org/W2111855638","https://openalex.org/W2112748255","https://openalex.org/W2112810155","https://openalex.org/W2113000896","https://openalex.org/W2113311378","https://openalex.org/W2114813165","https://openalex.org/W2116645953","https://openalex.org/W2119947460","https://openalex.org/W2121819501","https://openalex.org/W2124294874","https://openalex.org/W2125726678","https://openalex.org/W2126246455","https://openalex.org/W2127043059","https://openalex.org/W2128393824","https://openalex.org/W2128540669","https://openalex.org/W2129057663","https://openalex.org/W2129827681","https://openalex.org/W2130109710","https://openalex.org/W2130167819","https://openalex.org/W2131103881","https://openalex.org/W2131915942","https://openalex.org/W2135671488","https://openalex.org/W2136236728","https://openalex.org/W2136572822","https://openalex.org/W2141274038","https://openalex.org/W2142391786","https://openalex.org/W2146906100","https://openalex.org/W2148344434","https://openalex.org/W2148643959","https://openalex.org/W2151098145","https://openalex.org/W2151748492","https://openalex.org/W2152581536","https://openalex.org/W2154262967","https://openalex.org/W2154865008","https://openalex.org/W2156294821","https://openalex.org/W2159831861","https://openalex.org/W2160808472","https://openalex.org/W2162034430","https://openalex.org/W2164710273","https://openalex.org/W2166806711","https://openalex.org/W2167996887","https://openalex.org/W2168398697","https://openalex.org/W2170701570","https://openalex.org/W2319596822","https://openalex.org/W2322310797","https://openalex.org/W2460539353","https://openalex.org/W2560367415","https://openalex.org/W2755529213","https://openalex.org/W4206755376","https://openalex.org/W4238038517","https://openalex.org/W4245676516","https://openalex.org/W6631242087"],"related_works":["https://openalex.org/W2104449385","https://openalex.org/W1588992927","https://openalex.org/W1608728020","https://openalex.org/W7100351927","https://openalex.org/W2012053985","https://openalex.org/W1985469855","https://openalex.org/W7098092566","https://openalex.org/W4310364327","https://openalex.org/W2416890594","https://openalex.org/W2042492748"],"abstract_inverted_index":{"Persistent":[0],"infection":[1,77],"by":[2,149],"one":[3],"of":[4,18,20,40,52,64,111,123,129,145,152,178],"15":[5],"high-risk":[6],"human":[7,22],"papillomavirus":[8],"(hrHPV)":[9],"types":[10,42],"is":[11],"a":[12,26],"necessary":[13],"but":[14],"not":[15],"sufficient":[16],"cause":[17],"5%":[19],"all":[21,105],"cancers.":[23],"This":[24],"provides":[25],"remarkable":[27],"opportunity":[28],"for":[29,115,172],"cancer":[30,162,180],"prevention":[31,174],"via":[32],"immunization.":[33],"Since":[34],"Harald":[35],"zur":[36],"Hausen's":[37],"pioneering":[38],"identification":[39],"hrHPV":[41,106,146],"16":[43],"and":[44,50,78,92,126,141,164,175,181],"18,":[45],"found":[46],"in":[47,85],"approximately":[48],"50%":[49],"20%":[51],"cervical":[53,124,138,154,161,179],"cancers,":[54,98],"respectively,":[55],"two":[56],"prophylactic":[57],"HPV":[58,112,131],"vaccines":[59,72,113],"containing":[60],"virus-like":[61],"particles":[62],"(VLP)":[63],"each":[65],"genotype":[66],"have":[67,119,158],"been":[68],"widely":[69],"licensed.":[70],"These":[71],"are":[73],"beginning":[74],"to":[75,94,103],"affect":[76],"HPV-associated":[79,97],"neoplasia":[80,156],"rates":[81,122],"after":[82],"immunization":[83],"campaigns":[84],"adolescents.":[86],"Here,":[87],"we":[88,165],"review":[89],"recent":[90],"progress":[91],"opportunities":[93],"better":[95],"prevent":[96],"including":[99],"broadening":[100],"immune":[101],"protection":[102],"cover":[104],"types,":[107],"reducing":[108],"the":[109,120,173],"cost":[110],"especially":[114],"developing":[116],"countries":[117],"that":[118],"highest":[121],"cancer,":[125],"immune-based":[127,170],"treatment":[128,151],"established":[130],"infections.":[132],"Screening":[133],"based":[134],"upon":[135],"George":[136],"Papanicolaou's":[137],"cytology":[139],"testing,":[140],"more":[142],"recently":[143],"detection":[144],"DNA/RNA,":[147],"followed":[148],"ablative":[150],"high-grade":[153],"intraepithelial":[155],"(CIN2/3)":[157],"substantially":[159],"reduced":[160],"rates,":[163],"examine":[166],"their":[167],"interplay":[168],"with":[169],"modalities":[171],"eventual":[176],"elimination":[177],"other":[182],"HPV-related":[183],"malignancies.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":7}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}