{"id":"https://openalex.org/W2324966697","doi":"https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","title":"Response To Fluticasone And Montelukast Therapies Are Inversely Associated With A Common Variant Of The Corticotropin Releasing Hormone Receptor 1 (CRHR1) Gene","display_name":"Response To Fluticasone And Montelukast Therapies Are Inversely Associated With A Common Variant Of The Corticotropin Releasing Hormone Receptor 1 (CRHR1) Gene","publication_year":2011,"publication_date":"2011-05-01","ids":{"openalex":"https://openalex.org/W2324966697","doi":"https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","mag":"2324966697"},"language":"en","primary_location":{"id":"doi:10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","doi":"https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"C21. NEW TARGETS FOR ASTHMA THERAPY","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058754235","display_name":"Ed B. Mougey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ed B. Mougey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084598278","display_name":"Changzhong Chen","orcid":"https://orcid.org/0000-0001-9125-3457","observed_orcids":["https://orcid.org/0000-0001-9125-3457"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Changzhong Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079487486","display_name":"Kelan G. Tantisira","orcid":"https://orcid.org/0000-0003-2950-3384","observed_orcids":["https://orcid.org/0000-0003-2950-3384"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kelan Tantisira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040408813","display_name":"Kathryn Blake","orcid":"https://orcid.org/0000-0001-9959-8572","observed_orcids":["https://orcid.org/0000-0001-9959-8572"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathryn V. Blake","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047213494","display_name":"Stephen P. Peters","orcid":"https://orcid.org/0000-0003-4176-7999","observed_orcids":["https://orcid.org/0000-0003-4176-7999"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen P. Peters","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035047751","display_name":"Robert A. Wise","orcid":"https://orcid.org/0000-0002-8353-2349","observed_orcids":["https://orcid.org/0000-0002-8353-2349"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert A. Wise","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073763243","display_name":"Scott T. Weiss","orcid":"https://orcid.org/0000-0001-7196-303X","observed_orcids":["https://orcid.org/0000-0001-7196-303X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott T. Weiss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108423726","display_name":"John J. Lima","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John J. Lima","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"A4080","last_page":"A4080"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluticasone","display_name":"fluticasone","score":0.8920000195503235},{"id":"https://openalex.org/keywords/montelukast","display_name":"montelukast","score":1.0},{"id":"https://openalex.org/keywords/corticotropin-releasing-factor-receptor-1","display_name":"corticotropin-releasing hormone receptor 1","score":0.9139999747276306},{"id":"https://openalex.org/keywords/crhr1","display_name":"CRHR1","score":0.8199999928474426},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.8529999852180481},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.5550000071525574},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.6439999938011169},{"id":"https://openalex.org/keywords/corticosteroid-therapy","display_name":"corticosteroid therapy","score":0.6480000019073486},{"id":"https://openalex.org/keywords/leukotriene-receptor-antagonists","display_name":"leukotriene receptor antagonists","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C2776322731","wikidata":"https://www.wikidata.org/wiki/Q417767","display_name":"Montelukast","level":3,"score":0.7476139068603516},{"id":"https://openalex.org/C2781212218","wikidata":"https://www.wikidata.org/wiki/Q1002165","display_name":"Fluticasone","level":3,"score":0.5377678275108337},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.47323405742645264},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4362596273422241},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37399035692214966},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.343024879693985},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3150027394294739},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2638121545314789},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.09875130653381348}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","doi":"https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","is_oa":false,"landing_page_url":"https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4080","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"C21. NEW TARGETS FOR ASTHMA THERAPY","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2108449402","https://openalex.org/W2001587426","https://openalex.org/W2335252567","https://openalex.org/W2109071146","https://openalex.org/W2314990941","https://openalex.org/W4377232824","https://openalex.org/W2087730662","https://openalex.org/W2075611565","https://openalex.org/W2112468123","https://openalex.org/W1993656967"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}