{"id":"https://openalex.org/W2324914348","doi":"https://doi.org/10.3368/aoj.63.1.2","title":"Hemangiomas Treated with Propranolol: Do the Rewards Outweigh the Risks?","display_name":"Hemangiomas Treated with Propranolol: Do the Rewards Outweigh the Risks?","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2324914348","doi":"https://doi.org/10.3368/aoj.63.1.2","mag":"2324914348","pmid":"https://pubmed.ncbi.nlm.nih.gov/24260800"},"language":"en","primary_location":{"id":"doi:10.3368/aoj.63.1.2","doi":"https://doi.org/10.3368/aoj.63.1.2","is_oa":false,"landing_page_url":"https://doi.org/10.3368/aoj.63.1.2","pdf_url":null,"source":{"id":"https://openalex.org/S195882388","display_name":"American Orthoptic Journal","issn_l":"0065-955X","issn":["0065-955X","1553-4448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310315918","host_organization_name":"University of Wisconsin Press","host_organization_lineage":["https://openalex.org/P4310315918","https://openalex.org/P4310315897"],"host_organization_lineage_names":["University of Wisconsin Press","University of Wisconsin\u2013Madison"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Orthoptic Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016200123","display_name":"Kathryn M. Haider","orcid":"https://orcid.org/0000-0001-6498-2830","observed_orcids":["https://orcid.org/0000-0001-6498-2830"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kathryn M. Haider","raw_affiliation_strings":["Glick Eye Institute, Indianapolis, Indiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glick Eye Institute, Indianapolis, Indiana","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043670142","display_name":"Daniel E. Neely","orcid":"https://orcid.org/0000-0002-7984-9765","observed_orcids":["https://orcid.org/0000-0002-7984-9765"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel E. Neely","raw_affiliation_strings":["Glick Eye Institute, Indianapolis, Indiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glick Eye Institute, Indianapolis, Indiana","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000413403","display_name":"David A. Plager","orcid":"https://orcid.org/0000-0002-4746-4385","observed_orcids":["https://orcid.org/0000-0002-4746-4385"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David A. Plager","raw_affiliation_strings":["Glick Eye Institute, Indianapolis, Indiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glick Eye Institute, Indianapolis, Indiana","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5016200123"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.657,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.75479528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"63","issue":"1","first_page":"2","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10980","display_name":"Vascular Malformations and Hemangiomas","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10980","display_name":"Vascular Malformations and Hemangiomas","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/propranolol","display_name":"propranolol","score":0.9589999914169312},{"id":"https://openalex.org/keywords/infantile-hemangioma","display_name":"infantile hemangioma","score":0.8989999890327454},{"id":"https://openalex.org/keywords/pediatric-treatment","display_name":"pediatric treatment","score":0.3659999966621399},{"id":"https://openalex.org/keywords/systemic-corticosteroids","display_name":"systemic corticosteroids","score":0.8379999995231628},{"id":"https://openalex.org/keywords/hypoglycemia","display_name":"hypoglycemia","score":0.9369999766349792},{"id":"https://openalex.org/keywords/hypotension","display_name":"hypotension","score":0.9860000014305115},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.6919999718666077},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C2778151854","wikidata":"https://www.wikidata.org/wiki/Q423364","display_name":"Propranolol","level":2,"score":0.9490503072738647},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.921870231628418},{"id":"https://openalex.org/C2780668416","wikidata":"https://www.wikidata.org/wiki/Q202758","display_name":"Hypoglycemia","level":3,"score":0.656888484954834},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6044253706932068},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5347629189491272},{"id":"https://openalex.org/C3019900241","wikidata":"https://www.wikidata.org/wiki/Q52771370","display_name":"Infantile hemangioma","level":3,"score":0.510246753692627},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.40938934683799744},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3855002522468567},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33088576793670654},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.32694011926651},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15755602717399597},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.13938307762145996},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.08946320414543152},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006391","descriptor_name":"Hemangioma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009918","descriptor_name":"Orbital Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011433","descriptor_name":"Propranolol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3368/aoj.63.1.2","doi":"https://doi.org/10.3368/aoj.63.1.2","is_oa":false,"landing_page_url":"https://doi.org/10.3368/aoj.63.1.2","pdf_url":null,"source":{"id":"https://openalex.org/S195882388","display_name":"American Orthoptic Journal","issn_l":"0065-955X","issn":["0065-955X","1553-4448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310315918","host_organization_name":"University of Wisconsin Press","host_organization_lineage":["https://openalex.org/P4310315918","https://openalex.org/P4310315897"],"host_organization_lineage_names":["University of Wisconsin Press","University of Wisconsin\u2013Madison"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Orthoptic Journal","raw_type":"journal-article"},{"id":"pmid:24260800","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24260800","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American orthoptic journal","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1963910752","https://openalex.org/W1971918464","https://openalex.org/W1976197225","https://openalex.org/W1993123790","https://openalex.org/W2006037173","https://openalex.org/W2016073967","https://openalex.org/W2021578996","https://openalex.org/W2040333608","https://openalex.org/W2069785178","https://openalex.org/W2141812423","https://openalex.org/W2148017240","https://openalex.org/W2279578924"],"related_works":["https://openalex.org/W2145753364","https://openalex.org/W2896593065","https://openalex.org/W2095779896","https://openalex.org/W2318708747","https://openalex.org/W1494595620","https://openalex.org/W1976552410","https://openalex.org/W2488476586","https://openalex.org/W1971918464","https://openalex.org/W2787265186","https://openalex.org/W2320249589"],"abstract_inverted_index":{"Recent":[0],"reports":[1],"of":[2,7,49],"propranolol":[3,25],"for":[4,19],"the":[5,15],"treatment":[6,17],"hemangiomas":[8],"have":[9],"led":[10],"many":[11],"physicians":[12],"to":[13],"question":[14],"best":[16],"strategy":[18],"children":[20],"with":[21,45],"vision-threatening":[22],"hemangiomas.":[23],"Although":[24],"has":[26],"potential":[27],"side":[28,51],"effects,":[29],"including":[30],"hypoglycemia":[31],"and":[32],"hypotension,":[33],"early":[34],"studies":[35],"suggest":[36],"it":[37],"is":[38],"more":[39],"efficacious":[40],"than":[41],"systemic":[42],"cortico":[43],"steroids":[44],"a":[46],"lower":[47],"incidence":[48],"adverse":[50],"effects.":[52]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}