{"id":"https://openalex.org/W2323930585","doi":"https://doi.org/10.1007/dcr.0b013e3181fd4c7c","title":"Lymph Node Micrometastases and Isolated Tumor Cells Influence Survival in Stage I and II Colon Cancer","display_name":"Lymph Node Micrometastases and Isolated Tumor Cells Influence Survival in Stage I and II Colon Cancer","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W2323930585","doi":"https://doi.org/10.1007/dcr.0b013e3181fd4c7c","mag":"2323930585","pmid":"https://pubmed.ncbi.nlm.nih.gov/21228669"},"language":"en","primary_location":{"id":"doi:10.1007/dcr.0b013e3181fd4c7c","doi":"https://doi.org/10.1007/dcr.0b013e3181fd4c7c","is_oa":false,"landing_page_url":"https://doi.org/10.1007/dcr.0b013e3181fd4c7c","pdf_url":null,"source":{"id":"https://openalex.org/S170496595","display_name":"Diseases of the Colon & Rectum","issn_l":"0012-3706","issn":["0012-3706","1530-0358"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of the Colon & Rectum","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109997099","display_name":"Arne Engebreth F\u00e6rden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I2800192669","display_name":"Akershus University Hospital","ror":"https://ror.org/0331wat71","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800192669"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Arne E. Faerden","raw_affiliation_strings":["Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway. arneferden@tele2.no","Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway. arneferden@tele2.no","institution_ids":["https://openalex.org/I184942183","https://openalex.org/I2800192669"]},{"raw_affiliation_string":"Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183","https://openalex.org/I2800192669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109364178","display_name":"Ole Helmer Sjo","orcid":"https://orcid.org/0009-0000-6918-5101","observed_orcids":["https://orcid.org/0009-0000-6918-5101"]},"institutions":[{"id":"https://openalex.org/I1281400175","display_name":"Oslo University Hospital","ror":"https://ror.org/00j9c2840","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1281400175"]},{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Ole H. Sjo","raw_affiliation_strings":["Department of Digestive Surgery, Oslo University Hospital, Aker, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive Surgery, Oslo University Hospital, Aker, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I1281400175","https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056164574","display_name":"Ida Bukholm","orcid":"https://orcid.org/0000-0002-1712-9105","observed_orcids":["https://orcid.org/0000-0002-1712-9105"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I2800192669","display_name":"Akershus University Hospital","ror":"https://ror.org/0331wat71","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800192669"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Ida R. K. Bukholm","raw_affiliation_strings":["Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway","Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183","https://openalex.org/I2800192669"]},{"raw_affiliation_string":"Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109142913","display_name":"Solveig Norheim Andersen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I2800192669","display_name":"Akershus University Hospital","ror":"https://ror.org/0331wat71","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800192669"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Solveig Norheim Andersen","raw_affiliation_strings":["Department of Pathology, Akershus University Hospital, University of Oslo, Oslo, Norway","Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Akershus University Hospital, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183","https://openalex.org/I2800192669"]},{"raw_affiliation_string":"Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045407975","display_name":"Aud Svindland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1281400175","display_name":"Oslo University Hospital","ror":"https://ror.org/00j9c2840","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1281400175"]},{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Aud Svindland","raw_affiliation_strings":["Department of Pathology, Oslo University Hospital, Aker, University of Oslo, Oslo, Norway","Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Oslo University Hospital, Aker, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I1281400175","https://openalex.org/I184942183"]},{"raw_affiliation_string":"Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009602856","display_name":"Arild Nesbakken","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1281400175","display_name":"Oslo University Hospital","ror":"https://ror.org/00j9c2840","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1281400175"]},{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Arild Nesbakken","raw_affiliation_strings":["Department of Digestive Surgery, Oslo University Hospital, Aker, University of Oslo, Oslo, Norway","Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive Surgery, Oslo University Hospital, Aker, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I1281400175","https://openalex.org/I184942183"]},{"raw_affiliation_string":"Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069297948","display_name":"Arne Olav Bakka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I2800192669","display_name":"Akershus University Hospital","ror":"https://ror.org/0331wat71","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I2800192669"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Arne Bakka","raw_affiliation_strings":["Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway","Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183","https://openalex.org/I2800192669"]},{"raw_affiliation_string":"Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5109997099"],"corresponding_institution_ids":["https://openalex.org/I184942183","https://openalex.org/I2800192669"],"apc_list":null,"apc_paid":null,"fwci":5.838,"has_fulltext":false,"cited_by_count":87,"citation_normalized_percentile":{"value":0.97201013,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"54","issue":"2","first_page":"200","last_page":"206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.7509999871253967,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.7509999871253967,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.13210000097751617,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.040800001472234726,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.972000002861023},{"id":"https://openalex.org/keywords/lymph-node-micrometastases","display_name":"lymph node micrometastasis","score":0.9150000214576721},{"id":"https://openalex.org/keywords/isolated-tumor-cells","display_name":"isolated tumor cells","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lymph-node-status","display_name":"lymph node status","score":0.6380000114440918},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.7099999785423279},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.7379999756813049},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9760000109672546},{"id":"https://openalex.org/keywords/lymph-node-assessment","display_name":"lymph node examination","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9208403825759888},{"id":"https://openalex.org/C2778123414","wikidata":"https://www.wikidata.org/wiki/Q2779635","display_name":"Micrometastasis","level":4,"score":0.7364726066589355},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7093875408172607},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.6672542095184326},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.5653362274169922},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5566697716712952},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.5521449446678162},{"id":"https://openalex.org/C125473707","wikidata":"https://www.wikidata.org/wiki/Q9914","display_name":"H&E stain","level":3,"score":0.49846315383911133},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.49345293641090393},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.4838480055332184},{"id":"https://openalex.org/C2780283643","wikidata":"https://www.wikidata.org/wiki/Q2110267","display_name":"Primary tumor","level":4,"score":0.44284167885780334},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44233325123786926},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43728509545326233},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4314768314361572},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.36958104372024536},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008197","descriptor_name":"Lymph Node Excision","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/dcr.0b013e3181fd4c7c","doi":"https://doi.org/10.1007/dcr.0b013e3181fd4c7c","is_oa":false,"landing_page_url":"https://doi.org/10.1007/dcr.0b013e3181fd4c7c","pdf_url":null,"source":{"id":"https://openalex.org/S170496595","display_name":"Diseases of the Colon & Rectum","issn_l":"0012-3706","issn":["0012-3706","1530-0358"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of the Colon & Rectum","raw_type":"journal-article"},{"id":"pmid:21228669","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21228669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diseases of the colon and rectum","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W309257065","https://openalex.org/W1588649151","https://openalex.org/W1966626565","https://openalex.org/W1966997298","https://openalex.org/W1973938581","https://openalex.org/W1974386624","https://openalex.org/W1983337227","https://openalex.org/W1985976569","https://openalex.org/W1989453039","https://openalex.org/W1990545152","https://openalex.org/W1990748886","https://openalex.org/W2000652705","https://openalex.org/W2004935886","https://openalex.org/W2007332569","https://openalex.org/W2012181990","https://openalex.org/W2012314048","https://openalex.org/W2020830322","https://openalex.org/W2027826344","https://openalex.org/W2031840701","https://openalex.org/W2037330590","https://openalex.org/W2038993108","https://openalex.org/W2042926770","https://openalex.org/W2050772084","https://openalex.org/W2055801476","https://openalex.org/W2060083625","https://openalex.org/W2077468404","https://openalex.org/W2079372855","https://openalex.org/W2080152381","https://openalex.org/W2088993031","https://openalex.org/W2099032495","https://openalex.org/W2135357582","https://openalex.org/W2135973788","https://openalex.org/W2147961714","https://openalex.org/W2159352894","https://openalex.org/W2162838408","https://openalex.org/W2339671919","https://openalex.org/W6680241318"],"related_works":["https://openalex.org/W1989453039","https://openalex.org/W2045203764","https://openalex.org/W2050772084","https://openalex.org/W2044608166","https://openalex.org/W2380019446","https://openalex.org/W2275382940","https://openalex.org/W2020297912","https://openalex.org/W2135357582","https://openalex.org/W2161591026","https://openalex.org/W2339671919"],"abstract_inverted_index":{"PURPOSE:":[0],"Lymph-node":[1],"status":[2],"is":[3],"considered":[4],"the":[5,16,23,57],"most":[6],"important":[7],"prognostic":[8,213],"factor":[9,214],"in":[10,36,56,67,77,95,101,132],"colorectal":[11],"cancer.":[12,38,231],"The":[13,200],"aim":[14],"of":[15,25,42,109,122,125,135,202,227],"present":[17],"prospective":[18],"study":[19],"was":[20,171,208],"to":[21,210],"evaluate":[22],"influence":[24],"micrometastases":[26,112,140,150,166,203],"and":[27,33,52,69,113,164,173,204,217],"isolated":[28,117,142,152,168,184,205],"tumor":[29,118,143,153,169,185,206],"cells":[30,154,170,186,207],"on":[31,49],"recurrence":[32,131,216],"disease-free":[34,159,218],"survival":[35,160,192],"colon":[37,46,230],"METHODS:":[39],"A":[40,120],"total":[41],"193":[43],"patients":[44,100,138,162,182,195],"with":[45,85,139,146,163,183],"cancer,":[47],"operated":[48],"between":[50],"2000":[51],"2005,":[53],"were":[54,62,75,82,93],"enrolled":[55],"study.":[58],"All":[59],"lymph":[60],"nodes":[61,81],"examined":[63,83],"by":[64],"routine":[65],"microscopy":[66],"hematoxylin":[68],"eosin-stained":[70],"sections.":[71],"If":[72],"no":[73],"metastases":[74,92],"identified":[76],"any":[78],"node,":[79],"all":[80],"immunohistochemically":[84],"monoclonal":[86],"antibody":[87],"CAM":[88],"5.2.":[89],"RESULTS:":[90],"Ordinary":[91],"found":[94,209],"67":[96],"patients,":[97],"leaving":[98],"126":[99],"stage":[102,136,228],"I/II.":[103],"Immunohistochemistry":[104],"showed":[105],"that":[106],"5%":[107],"(6/126)":[108],"these":[110],"had":[111,116,189],"26%":[114],"(33/126)":[115],"cells.":[119],"median":[121],"5":[123],"years":[124],"follow-up":[126],"revealed":[127],"local":[128],"or":[129,141,151,167],"distant":[130],"23%":[133],"(9/39)":[134],"I/II":[137,229],"cells,":[144],"compared":[145],"7%":[147],"(6/87)":[148],"without":[149,165],"(P":[155,176,196],"=":[156,177,197],".010).":[157],"Five-year":[158],"for":[161,215,224],"75%":[172],"93%,":[174],"respectively":[175],".012).":[178,198],"When":[179],"analyzed":[180],"separately,":[181],"(excluding":[187],"micrometastases)":[188],"also":[190],"lower":[191],"than":[193],"node-negative":[194],"CONCLUSION:":[199],"presence":[201],"be":[211],"a":[212],"survival.":[219],"This":[220],"may":[221],"have":[222],"implications":[223],"future":[225],"treatment":[226]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}