{"id":"https://openalex.org/W2321923017","doi":"https://doi.org/10.1097/01.ccm.0000439945.68581.7a","title":"707","display_name":"707","publication_year":2013,"publication_date":"2013-11-26","ids":{"openalex":"https://openalex.org/W2321923017","doi":"https://doi.org/10.1097/01.ccm.0000439945.68581.7a","mag":"2321923017"},"language":"en","primary_location":{"id":"doi:10.1097/01.ccm.0000439945.68581.7a","doi":"https://doi.org/10.1097/01.ccm.0000439945.68581.7a","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0000439945.68581.7a","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082744234","display_name":"Yong Sing Da Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yong Sing Da Silva","raw_affiliation_strings":["Children's Hospital of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I4210130600"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047738826","display_name":"Melinda Fiedor Hamilton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melinda Hamilton","raw_affiliation_strings":["Children's Hospital of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I4210130600"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063956844","display_name":"Ericka L. Fink","orcid":"https://orcid.org/0000-0002-3683-4571","observed_orcids":["https://orcid.org/0000-0002-3683-4571"]},"institutions":[{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ericka Fink","raw_affiliation_strings":["Children's Hospital of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I4210130600"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058521832","display_name":"Robert S. B. Clark","orcid":"https://orcid.org/0000-0002-0806-8005","observed_orcids":["https://orcid.org/0000-0002-0806-8005"]},"institutions":[{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Clark","raw_affiliation_strings":["Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I4210130600"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210130600"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.19169866,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":null,"first_page":"A174","last_page":"A174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.46630001068115234,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.46630001068115234,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10645","display_name":"Cardiac Arrest and Resuscitation","score":0.25609999895095825,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13248","display_name":"Healthcare Technology and Patient Monitoring","score":0.1388999968767166,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-cardiac-arrest","display_name":"pediatric cardiac arrest","score":0.8920000195503235},{"id":"https://openalex.org/keywords/acute-decompensation","display_name":"acute decompensation","score":0.9269999861717224},{"id":"https://openalex.org/keywords/early-warning-systems","display_name":"early warning systems","score":0.6309999823570251},{"id":"https://openalex.org/keywords/electronic-health-records","display_name":"electronic health records","score":0.7519999742507935},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.39500001072883606},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7609999775886536},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.5400000214576721},{"id":"https://openalex.org/keywords/respiratory-rate","display_name":"respiratory rate","score":0.9890000224113464},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.7879999876022339},{"id":"https://openalex.org/keywords/hospitalized-children","display_name":"hospitalized children","score":0.4869999885559082},{"id":"https://openalex.org/keywords/lead-time","display_name":"lead time","score":0.503000020980835},{"id":"https://openalex.org/keywords/intensive-care-unit-admission","display_name":"intensive care unit admission","score":0.5040000081062317},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.3790000081062317},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9215201735496521},{"id":"https://openalex.org/C2778721985","wikidata":"https://www.wikidata.org/wiki/Q1183680","display_name":"Decompensation","level":2,"score":0.721981942653656},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.5633629560470581},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.563328206539154},{"id":"https://openalex.org/C3018060332","wikidata":"https://www.wikidata.org/wiki/Q10871684","display_name":"Electronic medical record","level":2,"score":0.5116851329803467},{"id":"https://openalex.org/C2781385661","wikidata":"https://www.wikidata.org/wiki/Q4677918","display_name":"Acute care","level":3,"score":0.4260568916797638},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.4213916063308716},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3979208171367645},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3711397647857666},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.22379377484321594},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1993127167224884},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.ccm.0000439945.68581.7a","doi":"https://doi.org/10.1097/01.ccm.0000439945.68581.7a","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0000439945.68581.7a","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.75,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2313772224","https://openalex.org/W2150577673","https://openalex.org/W4310084008","https://openalex.org/W7140223977","https://openalex.org/W2802264455","https://openalex.org/W2333797204","https://openalex.org/W2805344945","https://openalex.org/W4392772470","https://openalex.org/W4404183725","https://openalex.org/W3013027548"],"abstract_inverted_index":{"Introduction:":[0],"Inpatient":[1],"critical":[2,44],"events":[3],"including":[4],"cardiopulmonary":[5],"arrest":[6],"(CPA)":[7],"in":[8,270],"pediatric":[9,62,152,225,418],"patients":[10,63,153,226,256],"adversely":[11],"impacts":[12],"outcome.":[13],"Traditionally,":[14],"methods":[15],"for":[16,242],"anticipating":[17],"deterioration":[18,76,262],"rely":[19],"upon":[20],"observation":[21],"by":[22],"bedside":[23],"care":[24,112],"providers":[25],"and":[26,59,73,96,115,181,189,240,263,286,292,315,325,327,335,351,359,382,400,403],"sometimes":[27],"ward":[28],"based":[29],"telemetry,":[30],"both":[31,312],"generally":[32],"disconnected":[33],"from":[34,100,149,197,217,255,267,357,362],"medical":[35,106],"rapid":[36],"response":[37],"teams":[38],"that":[39],"would":[40,80],"respond":[41],"to":[42,49,54,68,135,178,210,307,370,391,421],"a":[43,87,117,129,157,193,198,218,234,322,331],"event":[45,278],"if":[46],"it":[47],"were":[48,176,207,245,273,305],"occur.":[50],"An":[51],"automated":[52],"system":[53,420],"complement":[55],"traditional":[56],"human-based":[57],"means":[58],"continuously":[60],"survey":[61],"hospital-wide":[64],"(particularly":[65],"where":[66],"patient":[67],"caregiver":[69],"ratios":[70],"are":[71],"high":[72],"recognition":[74],"of":[75,89,103,119,132,138,192,214,221,333,337,347,413],"may":[77],"be":[78,82,308,422],"delayed)":[79],"likely":[81],"beneficial.":[83],"Previously,":[84],"we":[85],"identified":[86],"set":[88,118,131],"risk":[90],"factors":[91],"associated":[92,310,375],"with":[93,257,311,376,410],"impending":[94,313,377],"CPA":[95,158,235,259,314,378],"acute":[97,165,203,237,261,380],"decompensation":[98,166,381],"gleaned":[99],"an":[101,164,415],"analysis":[102],"the":[104,243,271,411],"electronic":[105],"record":[107],"(EMR)":[108],"at":[109,171],"our":[110,172,367],"tertiary":[111,173],"Children's":[113,174],"Hospital":[114,175],"developed":[116,177],"sensitive":[120],"predictive":[121,384],"models":[122,143,206,244,344,395],"(CCM":[123],"2013;":[124],"A6980).":[125],"We've":[126],"now":[127],"added":[128],"control":[130,219],"EMR":[133,146,252,272,369],"data":[134,147,216,254,373],"determine":[136,179],"specificity":[137,336],"these":[139,394],"models.":[140,388],"Methods:":[141],"Predictive":[142],"using":[144,321,345,396],"existing":[145,368],"fields":[148],"220":[150],"hospitalized":[151,224],"who":[154,230],"experienced":[155],"either":[156],"(from":[159,167,227],"06/2006":[160,168],"-":[161,169],"11/2011)":[162],"or":[163,236,260,379],"07/2009)":[170],"sensitivity":[180,332],"lead":[182],"time.":[183],"Data":[184],"elements":[185,374],"included":[186],"physiologic":[187],"variables":[188,402],"RN-populated":[190],"documentation":[191],"'significant":[194],"clinical":[195,276],"event'":[196],"24":[199,211,264,303],"hour":[200],"period":[201],"preceding":[202],"events.":[204],"These":[205],"then":[208,246],"applied":[209],"h":[212,251,265,304],"epochs":[213,266],"EMR-based":[215,385],"group":[220],"378":[222],"age-matched":[223,268],"04/2007":[228],"-06/2009)":[229],"did":[231],"not":[232],"have":[233],"decompensation.":[238],"Sensitivities":[239],"specificities":[241,360],"calculated.":[247],"Results:":[248],"Twenty":[249],"four":[250],"pre-event":[253],"documented":[258],"controls":[269],"analyzed.":[274],"RN-documented":[275],"significant":[277],"(CSE),":[279],"heart":[280],"rate":[281,284],"(HR),":[282],"respiratory":[283],"(RR),":[285],"systolic":[287],"blood":[288,294],"pressure":[289,295],"(SBP)":[290],"above,":[291],"diastolic":[293],"(DBP)":[296],"below":[297],"age":[298],"adjusted":[299],"normal":[300],"ranges":[301],"within":[302],"found":[306],"frequently":[309],"emergent":[316],"ICU":[317],"intervention.":[318],"A":[319],"model":[320],"combination":[323],"CSE,":[324],"SBP":[326],"DBP":[328,352],"abnormalities":[329,353],"had":[330,354],"0.77":[334],"0.48.":[338],"Excluding":[339],"CSE":[340],"(which":[341],"remains":[342],"subjective),":[343],"combinations":[346],"HR,":[348],"RR,":[349],"SBP,":[350],"sensitivities":[355],"ranging":[356,361],"0.10-0.92":[358],"0.07-0.86.":[363],"Conclusions:":[364],"We":[365,389],"used":[366],"identify":[371],"real-time":[372],"construct":[383],"early":[386],"warning":[387],"plan":[390],"further":[392],"refine":[393],"non-binary":[397],"(yes/no":[398],"abnormality)":[399],"weighted":[401],"test":[404],"them":[405],"on":[406],"expanded":[407],"validation":[408],"sets,":[409],"objective":[412],"implementing":[414],"EMR-based,":[416],"bedside-complementary,":[417],"early-warning":[419],"tested":[423],"prospectively.":[424]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}