{"id":"https://openalex.org/W2321810332","doi":"https://doi.org/10.2307/2939197","title":"Early Termination of Pregnancy with Mifepristone (RU 486) and the Orally Active Prostaglandin Misoprostol.","display_name":"Early Termination of Pregnancy with Mifepristone (RU 486) and the Orally Active Prostaglandin Misoprostol.","publication_year":1993,"publication_date":"1993-07-01","ids":{"openalex":"https://openalex.org/W2321810332","doi":"https://doi.org/10.2307/2939197","mag":"2321810332"},"language":"en","primary_location":{"id":"doi:10.2307/2939197","doi":"https://doi.org/10.2307/2939197","is_oa":false,"landing_page_url":"https://doi.org/10.2307/2939197","pdf_url":null,"source":{"id":"https://openalex.org/S26966653","display_name":"Studies in Family Planning","issn_l":"0039-3665","issn":["0039-3665","1728-4465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Family Planning","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013591314","display_name":"R\u00e9mi Peyron","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Remi Peyron","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112393506","display_name":"Elisabeth Aubeny","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elisabeth Aubeny","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050780230","display_name":"Veronique Targosz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Veronique Targosz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085781691","display_name":"Louise Silvestre","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Louise Silvestre","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103634412","display_name":"Maguy Renault","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maguy Renault","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111605453","display_name":"Fran\u00e7ois Elkik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francois Elkik","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Philippe Leclerc","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Philippe Leclerc","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109994346","display_name":"Andr\u00e9 Ulmann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andre Ulmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5105781312","display_name":"\u00c9tienne-\u00c9mile Baulieu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Etienne-Emile Baulieu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":null,"fwci":1.034,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.79279668,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"24","issue":"4","first_page":"266","last_page":"266"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13942","display_name":"International Human Rights and Reproductive Law","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3320","display_name":"Political Science and International Relations"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mifepristone","display_name":"mifepristone","score":0.8510000109672546},{"id":"https://openalex.org/keywords/misoprostol","display_name":"misoprostol","score":0.9589999914169312},{"id":"https://openalex.org/keywords/ru486","display_name":"RU486","score":0.8309999704360962},{"id":"https://openalex.org/keywords/medication-abortion","display_name":"abortion pills","score":0.6259999871253967},{"id":"https://openalex.org/keywords/early-pregnancy-termination","display_name":"early pregnancy termination","score":0.875},{"id":"https://openalex.org/keywords/oral-misoprostol","display_name":"oral misoprostol","score":0.828000009059906},{"id":"https://openalex.org/keywords/prostaglandin-e1-analog","display_name":"prostaglandin E1 analogue","score":0.8529999852180481},{"id":"https://openalex.org/keywords/abortion-efficacy","display_name":"abortion efficacy","score":0.625},{"id":"https://openalex.org/keywords/complete-abortion","display_name":"complete abortion","score":0.3059999942779541}],"concepts":[{"id":"https://openalex.org/C2778826759","wikidata":"https://www.wikidata.org/wiki/Q411240","display_name":"Mifepristone","level":3,"score":0.9581749439239502},{"id":"https://openalex.org/C2779199973","wikidata":"https://www.wikidata.org/wiki/Q416025","display_name":"Misoprostol","level":4,"score":0.9335431456565857},{"id":"https://openalex.org/C2779526769","wikidata":"https://www.wikidata.org/wiki/Q4859319","display_name":"Prostaglandin analogue","level":3,"score":0.6734148263931274},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6513046026229858},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.611547589302063},{"id":"https://openalex.org/C2778642596","wikidata":"https://www.wikidata.org/wiki/Q8452","display_name":"Abortion","level":3,"score":0.5183368921279907},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4942364990711212},{"id":"https://openalex.org/C3017990168","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Orally active","level":3,"score":0.4405995011329651},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.42441245913505554},{"id":"https://openalex.org/C2780664492","wikidata":"https://www.wikidata.org/wiki/Q209717","display_name":"Prostaglandin","level":2,"score":0.4021506607532501},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.24642106890678406},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16690906882286072},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06056436896324158},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2307/2939197","doi":"https://doi.org/10.2307/2939197","is_oa":false,"landing_page_url":"https://doi.org/10.2307/2939197","pdf_url":null,"source":{"id":"https://openalex.org/S26966653","display_name":"Studies in Family Planning","issn_l":"0039-3665","issn":["0039-3665","1728-4465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Family Planning","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2339185636","https://openalex.org/W2319731014","https://openalex.org/W111552580","https://openalex.org/W2087606036","https://openalex.org/W2020197724","https://openalex.org/W891588525","https://openalex.org/W2888819994","https://openalex.org/W2396869632","https://openalex.org/W2470925640","https://openalex.org/W2162260833"],"abstract_inverted_index":{"Background":[0],"and":[1,9,35,149],"Methods":[2],"The":[3],"combination":[4],"of":[5,28,47,50,57,87,127,136,144,147,152],"mifepristone":[6,51],"(RU":[7],"486)":[8],"a":[10,54],"prostaglandin":[11,26,62],"analogue":[12],"given":[13],"either":[14],"intramuscularly":[15],"or":[16],"intravaginally":[17],"is":[18,31],"effective":[19],"in":[20],"terminating":[21],"early":[22],"pregnancy,":[23],"but":[24,114],"the":[25,29,45,66,70,95,104,111,116,125,142,153],"component":[27],"regimen":[30],"cumbersome":[32],"to":[33,43],"administer":[34],"has":[36],"side":[37],"effects.":[38],"We":[39],"conducted":[40],"two":[41],"studies":[42],"determine":[44],"efficacy":[46],"600":[48],"mg":[49],"followed":[52],"by":[53],"small":[55],"dose":[56,135],"misoprostol,":[58,128],"an":[59,132],"orally":[60],"active":[61],"E1":[63],"analogue,":[64],"for":[65,79],"same":[67,112],"purpose.":[68],"In":[69,103,139],"first":[71],"study,":[72,106],"505":[73],"women":[74,108],"who":[75],"had":[76,77],"amenorrhea":[78],"less":[80],"than":[81],"50":[82],"days":[83],"received":[84,110],"400":[85],"\u03bcg":[86],"misoprostol":[88],"48":[89],"hours":[90,123],"after":[91,124],"receiving":[92],"mifepristone,":[93],"if":[94,115],"pregnancy":[96,117,148],"was":[97,118,155],"not":[98,119],"terminated":[99,120],"within":[100,121],"that":[101],"period.":[102],"second":[105],"390":[107],"initially":[109],"treatment,":[113],"four":[122],"administration":[126],"they":[129],"were":[130],"offered":[131],"additional":[133],"200-\u03bcg":[134],"misoprostol.":[137],"Results":[138],"study":[140],"1,":[141],"rate":[143],"success":[145],"(termination":[146],"complete":[150],"expulsion":[151],"conceptus)":[154],"96.9":[156],"percent":[157],"...":[158]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}