{"id":"https://openalex.org/W2321733235","doi":"https://doi.org/10.1021/jf202110f","title":"Detection of Allergenic Ingredients Using Real-Time PCR: A Case Study on Hazelnut (Corylus avellena) and Soy (Glycine max)","display_name":"Detection of Allergenic Ingredients Using Real-Time PCR: A Case Study on Hazelnut (Corylus avellena) and Soy (Glycine max)","publication_year":2011,"publication_date":"2011-09-04","ids":{"openalex":"https://openalex.org/W2321733235","doi":"https://doi.org/10.1021/jf202110f","mag":"2321733235","pmid":"https://pubmed.ncbi.nlm.nih.gov/21888436"},"language":"en","primary_location":{"id":"doi:10.1021/jf202110f","doi":"https://doi.org/10.1021/jf202110f","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jf202110f","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083274412","display_name":"C\u00e9line Platteau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145253","display_name":"Instituut voor Landbouw en Visserijonderzoek","ror":"https://ror.org/05cjt1n05","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210145253"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"C\u00e9line Platteau","raw_affiliation_strings":["Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Merelbeke, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Merelbeke, Belgium","institution_ids":["https://openalex.org/I4210145253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033815710","display_name":"Marc De Loose","orcid":"https://orcid.org/0000-0002-2386-3410","observed_orcids":["https://orcid.org/0000-0002-2386-3410"]},"institutions":[{"id":"https://openalex.org/I4210145253","display_name":"Instituut voor Landbouw en Visserijonderzoek","ror":"https://ror.org/05cjt1n05","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210145253"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marc De Loose","raw_affiliation_strings":["Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Merelbeke, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Merelbeke, Belgium","institution_ids":["https://openalex.org/I4210145253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002455553","display_name":"Bruno De Meulenaer","orcid":"https://orcid.org/0000-0003-0121-5567","observed_orcids":["https://orcid.org/0000-0003-0121-5567"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bruno De Meulenaer","raw_affiliation_strings":["Department of Food Safety and Food Quality, Research Group Food Chemistry and Human Nutrition, Ghent University, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Safety and Food Quality, Research Group Food Chemistry and Human Nutrition, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053169087","display_name":"Isabel Taverniers","orcid":"https://orcid.org/0000-0003-0515-3412","observed_orcids":["https://orcid.org/0000-0003-0515-3412"]},"institutions":[{"id":"https://openalex.org/I4210145253","display_name":"Instituut voor Landbouw en Visserijonderzoek","ror":"https://ror.org/05cjt1n05","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210145253"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Isabel Taverniers","raw_affiliation_strings":["Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Merelbeke, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Merelbeke, Belgium","institution_ids":["https://openalex.org/I4210145253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5083274412"],"corresponding_institution_ids":["https://openalex.org/I4210145253"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.4979,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.81971307,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"59","issue":"20","first_page":"10803","last_page":"10814"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12388","display_name":"Identification and Quantification in Food","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12388","display_name":"Identification and Quantification in Food","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.04170000180602074,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergen-detection","display_name":"allergen testing","score":0.8740000128746033},{"id":"https://openalex.org/keywords/hazelnut","display_name":"hazelnut","score":0.906000018119812},{"id":"https://openalex.org/keywords/corylus-avellana","display_name":"Corylus avellana","score":0.9539999961853027},{"id":"https://openalex.org/keywords/soybean","display_name":"soybean","score":1.0},{"id":"https://openalex.org/keywords/real-time-pcr","display_name":"real-time PCR","score":0.8410000205039978},{"id":"https://openalex.org/keywords/food-allergen-labeling","display_name":"food allergen labeling","score":0.7540000081062317},{"id":"https://openalex.org/keywords/cross-reactivity","display_name":"cross-reactivity","score":0.9350000023841858},{"id":"https://openalex.org/keywords/allergen-quantification","display_name":"allergen quantification","score":0.7730000019073486},{"id":"https://openalex.org/keywords/reference-materials","display_name":"reference materials","score":0.7639999985694885},{"id":"https://openalex.org/keywords/food-contamination","display_name":"food contamination","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C2780589914","wikidata":"https://www.wikidata.org/wiki/Q10675206","display_name":"Ingredient","level":2,"score":0.7025256752967834},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.6830272674560547},{"id":"https://openalex.org/C3020576271","wikidata":"https://www.wikidata.org/wiki/Q769815","display_name":"Food allergens","level":4,"score":0.6727162599563599},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.6059495806694031},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4623362720012665},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.403878390789032},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27944716811180115},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.2520221769809723},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09783607721328735}],"mesh":[{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005512","descriptor_name":"Food Hypersensitivity","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D005515","descriptor_name":"Food Labeling","qualifier_ui":"Q000331","qualifier_name":"legislation & jurisprudence","is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013025","descriptor_name":"Glycine max","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013025","descriptor_name":"Glycine max","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D031211","descriptor_name":"Corylus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D031211","descriptor_name":"Corylus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D060888","descriptor_name":"Real-Time Polymerase Chain Reaction","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1021/jf202110f","doi":"https://doi.org/10.1021/jf202110f","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jf202110f","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},{"id":"pmid:21888436","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21888436","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of agricultural and food chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:archive.ugent.be:2136283","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1854/LU-2136283","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 0021-8561","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.6735000014305115,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321454","display_name":"Belgian Federal Science Policy Office","ror":"https://ror.org/01fapfv42"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W903383476","https://openalex.org/W1499500424","https://openalex.org/W1602801748","https://openalex.org/W1738950055","https://openalex.org/W1974535045","https://openalex.org/W1977047563","https://openalex.org/W1981091632","https://openalex.org/W2008374744","https://openalex.org/W2010148475","https://openalex.org/W2012280425","https://openalex.org/W2015098735","https://openalex.org/W2019730961","https://openalex.org/W2028547014","https://openalex.org/W2037850951","https://openalex.org/W2039681715","https://openalex.org/W2041594259","https://openalex.org/W2055192651","https://openalex.org/W2064984085","https://openalex.org/W2066381812","https://openalex.org/W2069040083","https://openalex.org/W2071923813","https://openalex.org/W2085091515","https://openalex.org/W2090280060","https://openalex.org/W2093371950","https://openalex.org/W2113074959","https://openalex.org/W2130299820","https://openalex.org/W2137450588","https://openalex.org/W2163216014","https://openalex.org/W2167792556","https://openalex.org/W2170976761","https://openalex.org/W2328899150","https://openalex.org/W2406831440","https://openalex.org/W2410571880","https://openalex.org/W2435526457"],"related_works":["https://openalex.org/W2323299419","https://openalex.org/W1974535045","https://openalex.org/W4386077650","https://openalex.org/W2211049334","https://openalex.org/W2375239096","https://openalex.org/W2037900648","https://openalex.org/W2116892360","https://openalex.org/W2015098735","https://openalex.org/W1977047563","https://openalex.org/W3047925487"],"abstract_inverted_index":{"Compliance":[0],"with":[1,14,48,84],"the":[2,25,36,53,61,72,80,94,131,145,156],"European":[3],"allergen":[4,117,151],"labeling":[5],"legislation":[6],"(Directive":[7],"2007/68/EC)":[8],"is":[9,153],"only":[10],"possible":[11],"when":[12],"coupled":[13],"appropriate":[15,159],"methods":[16],"to":[17,29,67,101,112,124,127,138],"detect":[18],"allergens":[19],"in":[20,136],"food.":[21],"The":[22,97],"aim":[23],"of":[24,38,77,79,121,133,147,158],"current":[26],"study":[27,74,142],"was":[28],"develop":[30],"new":[31,54],"real-time":[32,148],"PCR":[33,149],"assays":[34,45,55,98],"for":[35,93,116,150,162],"detection":[37,118],"hazelnut":[39,86],"and":[40,42],"soy":[41],"evaluate":[43],"these":[44],"via":[46],"comparison":[47],"commercially":[49],"available":[50],"kits.":[51],"Although":[52],"were":[56,99],"not":[57],"as":[58,60,103,105],"sensitive":[59],"commercial":[62],"qualitative":[63],"assays,":[64],"they":[65],"proved":[66],"be":[68,125,139],"more":[69],"specific.":[70],"Moreover,":[71],"cross-reactivity":[73],"indicated":[75],"contamination":[76],"some":[78],"food":[81],"products":[82],"used":[83,111],"either":[85],"or":[87],"soy,":[88],"which":[89],"presents":[90],"a":[91,128],"risk":[92],"allergic":[95],"consumer.":[96],"able":[100],"quantify":[102],"few":[104],"5-15":[106],"genome":[107],"copies.":[108],"This":[109,141],"unit,":[110],"express":[113],"analytical":[114],"results":[115],"by":[119,155],"means":[120],"PCR,":[122],"needs":[123],"converted":[126],"unit":[129],"expressing":[130],"amount":[132],"allergenic":[134],"ingredient":[135],"order":[137],"informative.":[140],"emphasizes":[143],"that":[144],"use":[146],"quantification":[152],"complicated":[154],"lack":[157],"reference":[160],"materials":[161],"allergens.":[163]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}