{"id":"https://openalex.org/W2321159918","doi":"https://doi.org/10.1055/s-0031-1300422","title":"Effect of Treatment with 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors on Serum Coenzyme Q10 in Diabetic Patients","display_name":"Effect of Treatment with 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors on Serum Coenzyme Q10 in Diabetic Patients","publication_year":2011,"publication_date":"2011-12-28","ids":{"openalex":"https://openalex.org/W2321159918","doi":"https://doi.org/10.1055/s-0031-1300422","mag":"2321159918","pmid":"https://pubmed.ncbi.nlm.nih.gov/10337451"},"language":"en","primary_location":{"id":"doi:10.1055/s-0031-1300422","doi":"https://doi.org/10.1055/s-0031-1300422","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0031-1300422","pdf_url":null,"source":{"id":"https://openalex.org/S132758211","display_name":"Arzneimittelforschung","issn_l":"0004-4172","issn":["0004-4172","1616-7066"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arzneimittelforschung","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044663909","display_name":"Yutaka Miyake","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaka Miyake","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052408363","display_name":"Akira Shouzu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Shouzu","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077581552","display_name":"Mitsushige Nishikawa","orcid":"https://orcid.org/0009-0007-6307-3425","observed_orcids":["https://orcid.org/0009-0007-6307-3425"]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsushige Nishikawa","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111729501","display_name":"Toshinaga Yonemoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshinaga Yonemoto","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110763938","display_name":"Hidekazu Shimizu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidekazu Shimizu","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111543603","display_name":"Seitaro Omoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Seitaro Omoto","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063890054","display_name":"Takassh Hayakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takassh Hayakawa","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064080554","display_name":"Mitsuo Inada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126884977","display_name":"Kansai Medical University","ror":"https://ror.org/001xjdh50","country_code":"JP","type":"education","lineage":["https://openalex.org/I126884977"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuo Inada","raw_affiliation_strings":["Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Department of Internal Medicine (Director: Mitsuo Inada), Kansai Medical University","institution_ids":["https://openalex.org/I126884977"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I126884977"],"apc_list":null,"apc_paid":null,"fwci":1.1769,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.77071554,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"49","issue":"04","first_page":"324","last_page":"329"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coenzyme-q10","display_name":"coenzyme Q10","score":0.9789999723434448},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.9380000233650208},{"id":"https://openalex.org/keywords/simvastatin","display_name":"simvastatin","score":0.9480000138282776},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8880000114440918},{"id":"https://openalex.org/keywords/cholesterol-lowering-therapy","display_name":"cholesterol-lowering therapy","score":0.75},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.8479999899864197},{"id":"https://openalex.org/keywords/familial-hypercholesterolemia","display_name":"familial hypercholesterolemia","score":0.8669999837875366},{"id":"https://openalex.org/keywords/ldl-apheresis","display_name":"LDL apheresis","score":0.9179999828338623},{"id":"https://openalex.org/keywords/coenzyme-q10-supplementation","display_name":"coenzyme Q10 supplementation","score":0.8650000095367432},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.6690000295639038},{"id":"https://openalex.org/keywords/cardiothoracic-ratio","display_name":"cardiothoracic ratio","score":0.8059999942779541},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.3400000035762787}],"concepts":[{"id":"https://openalex.org/C2776329913","wikidata":"https://www.wikidata.org/wiki/Q670131","display_name":"Simvastatin","level":2,"score":0.8339589238166809},{"id":"https://openalex.org/C2779384338","wikidata":"https://www.wikidata.org/wiki/Q321285","display_name":"Coenzyme Q10","level":2,"score":0.8057840466499329},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.800331175327301},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7218454480171204},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.6112213134765625},{"id":"https://openalex.org/C2779123261","wikidata":"https://www.wikidata.org/wiki/Q407635","display_name":"Coenzyme A","level":4,"score":0.6022509932518005},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6021490693092346},{"id":"https://openalex.org/C104950815","wikidata":"https://www.wikidata.org/wiki/Q415607","display_name":"HMG-CoA reductase","level":4,"score":0.588508129119873},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.5844618082046509},{"id":"https://openalex.org/C2777320049","wikidata":"https://www.wikidata.org/wiki/Q2989497","display_name":"Hydroxymethylglutaryl-CoA reductase","level":5,"score":0.5061325430870056},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4981091022491455},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.31672561168670654},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15948760509490967},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14557558298110962}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000924","descriptor_name":"Anticholesteremic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000924","descriptor_name":"Anticholesteremic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003067","descriptor_name":"Coenzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017035","descriptor_name":"Pravastatin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019821","descriptor_name":"Simvastatin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1055/s-0031-1300422","doi":"https://doi.org/10.1055/s-0031-1300422","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0031-1300422","pdf_url":null,"source":{"id":"https://openalex.org/S132758211","display_name":"Arzneimittelforschung","issn_l":"0004-4172","issn":["0004-4172","1616-7066"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arzneimittelforschung","raw_type":"journal-article"},{"id":"pmid:10337451","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10337451","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arzneimittel-Forschung","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2892976384","https://openalex.org/W3011566892","https://openalex.org/W2411691717","https://openalex.org/W2481035428","https://openalex.org/W2279928618","https://openalex.org/W2522591835","https://openalex.org/W280190835","https://openalex.org/W1964874366","https://openalex.org/W2983303096","https://openalex.org/W2035787556"],"abstract_inverted_index":{"Serum":[0],"coenzyme":[1,77],"Q10":[2],"(CoQ10:":[3],"2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34":[4],",38":[5],"-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone,":[6],"CAS":[7],"303-98-0)":[8],"and":[9,34,194],"cholesterol":[10,68,166],"levels":[11,188],"were":[12,40,56,110],"measured":[13],"to":[14,158,180],"assess":[15],"the":[16],"effect":[17],"of":[18,75],"cholesterol-lowering":[19],"therapy":[20],"in":[21,62,118,141,189],"patients":[22,33,36,64,120,143,191],"with":[23,37,65,71,95,121,134,198],"non-insulin-dependent":[24],"diabetes":[25],"mellitus":[26],"(NIDDM).":[27],"Twenty":[28],"healthy":[29],"volunteers,":[30],"97":[31],"NIDDM":[32,190],"2":[35],"familial":[38],"hypercholesterolemia":[39],"studied.":[41],"None":[42],"had":[43],"overt":[44],"heart":[45,50],"failure":[46],"or":[47,72,124],"any":[48],"other":[49],"disease.":[51],"Mean":[52],"serum":[53,67,130,136,152,186],"CoQ10":[54,108,131,139,153,187,204],"concentrations":[55,109,132],"significantly":[57,147,169],"(p":[58,148,170],"<":[59,116,149,171],"0.01)":[60],"lower":[61],"diabetic":[63,94,101,119,142,200],"normal":[66],"concentrations,":[69],"either":[70],"without":[73,102,164],"administration":[74],"3-hydroxy-3-methylglutaryl":[76],"A":[78],"reductase":[79],"inhibitors":[80],"(HMG-CoA":[81],"RIs)":[82],"including":[83],"simvastatin":[84],"(normal:":[85],"0.91":[86],"+/-":[87,90,99,106,113,156,160,178,182],"0.26":[88],"(mean":[89],"SD)":[91],"mumol":[92,162],"1(-1);":[93],"HMG-CoA":[96,103,145],"RI:":[97,104],"0.63":[98],"0.19;":[100],"0.66":[105],"0.21).":[107],"higher":[111],"(1.37":[112],"0.48,":[114],"p":[115],"0.001)":[117,150],"hypercholesterolemia.":[122],"Simvastatin":[123],"low":[125],"density":[126],"lipoprotein":[127],"apheresis":[128],"decreased":[129,173,193],"along":[133],"decreasing":[135],"cholesterol.":[137],"Oral":[138],"supplementation":[140],"receiving":[144],"RI":[146],"increased":[151],"from":[154,176],"0.81":[155],"0.24":[157],"1.47":[159],"0.44":[161],"1(-1),":[163],"affecting":[165],"levels.":[167],"It":[168],"0.03)":[172],"cardiothoracic":[174],"ratios":[175],"51.4":[177],"5.1":[179],"49.2":[181],"4.7%.":[183],"In":[184],"conclusion,":[185],"are":[192],"may":[195],"be":[196],"associated":[197],"subclinical":[199],"cardiomyopathy":[201],"reversible":[202],"by":[203],"supplementation.":[205]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}