{"id":"https://openalex.org/W2321081934","doi":"https://doi.org/10.1016/j.stem.2016.03.017","title":"Stem Cells Expand Insights into Human Brain Evolution","display_name":"Stem Cells Expand Insights into Human Brain Evolution","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W2321081934","doi":"https://doi.org/10.1016/j.stem.2016.03.017","mag":"2321081934","pmid":"https://pubmed.ncbi.nlm.nih.gov/27058930"},"language":"en","primary_location":{"id":"doi:10.1016/j.stem.2016.03.017","doi":"https://doi.org/10.1016/j.stem.2016.03.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stem.2016.03.017","pdf_url":"http://www.cell.com/article/S1934590916300066/pdf","source":{"id":"https://openalex.org/S128124174","display_name":"Cell stem cell","issn_l":"1875-9777","issn":["1875-9777","1934-5909"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stem Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1934590916300066/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023634801","display_name":"Michael A. Dyer","orcid":"https://orcid.org/0000-0003-4027-4850","observed_orcids":["https://orcid.org/0000-0003-4027-4850"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael\u00a0A. Dyer","raw_affiliation_strings":["Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: michael.dyer@stjude.org","Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA","Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: michael.dyer@stjude.org","institution_ids":["https://openalex.org/I1313298211","https://openalex.org/I1344073410"]},{"raw_affiliation_string":"Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA","institution_ids":["https://openalex.org/I1313298211"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA","institution_ids":["https://openalex.org/I1344073410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023634801"],"corresponding_institution_ids":["https://openalex.org/I1313298211","https://openalex.org/I1344073410"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":1.1255,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.7237435,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"18","issue":"4","first_page":"425","last_page":"426"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-brain-evolution","display_name":"human brain evolution","score":0.8389999866485596},{"id":"https://openalex.org/keywords/species-differences","display_name":"species differences","score":0.6230000257492065},{"id":"https://openalex.org/keywords/brain-organoids","display_name":"brain organoids","score":0.7160000205039978},{"id":"https://openalex.org/keywords/induced-pluripotent-stem-cells","display_name":"induced pluripotent stem cells","score":0.847000002861023}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9184175729751587},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6981747150421143},{"id":"https://openalex.org/C31695470","wikidata":"https://www.wikidata.org/wiki/Q11293125","display_name":"Organoid","level":2,"score":0.6345397233963013},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6332957744598389},{"id":"https://openalex.org/C15729860","wikidata":"https://www.wikidata.org/wiki/Q2329919","display_name":"Progenitor","level":4,"score":0.6228359937667847},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.5925544500350952},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.5509402751922607},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5275732278823853},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.47363749146461487},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.4351285398006439},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3640778064727783},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.22616836428642273}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.stem.2016.03.017","doi":"https://doi.org/10.1016/j.stem.2016.03.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stem.2016.03.017","pdf_url":"http://www.cell.com/article/S1934590916300066/pdf","source":{"id":"https://openalex.org/S128124174","display_name":"Cell stem cell","issn_l":"1875-9777","issn":["1875-9777","1934-5909"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stem Cell","raw_type":"journal-article"},{"id":"pmid:27058930","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27058930","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell stem cell","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.stem.2016.03.017","doi":"https://doi.org/10.1016/j.stem.2016.03.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stem.2016.03.017","pdf_url":"http://www.cell.com/article/S1934590916300066/pdf","source":{"id":"https://openalex.org/S128124174","display_name":"Cell stem cell","issn_l":"1875-9777","issn":["1875-9777","1934-5909"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stem Cell","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2564262008","display_name":"Wellcome Trust MRC Cambridge Stem Cell Institute","funder_award_id":"MC_PC_12009","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G3844694168","display_name":"Proliferation and Differentiation of Retinal Stem Cells","funder_award_id":"R01EY018599","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6506526940","display_name":"Epigenetic Reprogramming of Retinal Neurons","funder_award_id":"R01EY023619","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2321081934.pdf"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1522174931","https://openalex.org/W1963718340","https://openalex.org/W1972968697","https://openalex.org/W2033231119","https://openalex.org/W2052063322","https://openalex.org/W2054362072","https://openalex.org/W2066556283","https://openalex.org/W2156200367","https://openalex.org/W2169786878","https://openalex.org/W2330595735"],"related_works":["https://openalex.org/W7169886733","https://openalex.org/W3156079811","https://openalex.org/W1970756199","https://openalex.org/W2507869780","https://openalex.org/W2330595735","https://openalex.org/W2584287700","https://openalex.org/W3001656075","https://openalex.org/W2549988107","https://openalex.org/W2309897145","https://openalex.org/W2944618467"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}