{"id":"https://openalex.org/W2321037082","doi":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","title":"P10 Risks of low molecular weight Heparin in suspected pulmonary embolism","display_name":"P10 Risks of low molecular weight Heparin in suspected pulmonary embolism","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W2321037082","doi":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","mag":"2321037082"},"language":"en","primary_location":{"id":"doi:10.1136/thoraxjnl-2011-201054c.10","doi":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","is_oa":true,"landing_page_url":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","pdf_url":"https://thorax.bmj.com/content/thoraxjnl/66/Suppl_4/A70.3.full.pdf","source":{"id":"https://openalex.org/S106546978","display_name":"Thorax","issn_l":"0040-6376","issn":["0040-6376","1468-3296"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://thorax.bmj.com/content/thoraxjnl/66/Suppl_4/A70.3.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"L. Watkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800695023","display_name":"Mersey and West Lancashire Teaching Hospitals NHS Trust","ror":"https://ror.org/02e6wxz44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"L. Watkins","raw_affiliation_strings":["St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK","institution_ids":["https://openalex.org/I2800695023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112075192","display_name":"S. Rafeeq","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800695023","display_name":"Mersey and West Lancashire Teaching Hospitals NHS Trust","ror":"https://ror.org/02e6wxz44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Rafeeq","raw_affiliation_strings":["St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK","institution_ids":["https://openalex.org/I2800695023"]}]},{"author_position":"middle","author":{"id":null,"display_name":"N. McMullan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800695023","display_name":"Mersey and West Lancashire Teaching Hospitals NHS Trust","ror":"https://ror.org/02e6wxz44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N. McMullan","raw_affiliation_strings":["St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK","institution_ids":["https://openalex.org/I2800695023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051827801","display_name":"Paul Stockton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800695023","display_name":"Mersey and West Lancashire Teaching Hospitals NHS Trust","ror":"https://ror.org/02e6wxz44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. Stockton","raw_affiliation_strings":["St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK","institution_ids":["https://openalex.org/I2800695023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038450572","display_name":"Simon Twite","orcid":"https://orcid.org/0000-0002-7688-5437","observed_orcids":["https://orcid.org/0000-0002-7688-5437"]},"institutions":[{"id":"https://openalex.org/I2800695023","display_name":"Mersey and West Lancashire Teaching Hospitals NHS Trust","ror":"https://ror.org/02e6wxz44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Twite","raw_affiliation_strings":["St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK","institution_ids":["https://openalex.org/I2800695023"]}]},{"author_position":"last","author":{"id":null,"display_name":"S. Agarwal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800695023","display_name":"Mersey and West Lancashire Teaching Hospitals NHS Trust","ror":"https://ror.org/02e6wxz44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Agarwal","raw_affiliation_strings":["St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, UK","institution_ids":["https://openalex.org/I2800695023"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2800695023"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"66","issue":"Suppl 4","first_page":"A70","last_page":"A71"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10508","display_name":"Patient Safety and Medication Errors","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/low-molecular-weight-heparin","display_name":"low molecular weight heparin","score":1.0},{"id":"https://openalex.org/keywords/pulmonary-embolism","display_name":"pulmonary embolism","score":0.9340000152587891},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.32499998807907104},{"id":"https://openalex.org/keywords/dosing-errors","display_name":"dosing errors","score":0.7020000219345093},{"id":"https://openalex.org/keywords/patient-weight","display_name":"patient weight","score":0.48500001430511475},{"id":"https://openalex.org/keywords/creatinine-clearance","display_name":"creatinine clearance","score":0.9860000014305115},{"id":"https://openalex.org/keywords/inappropriate-prescribing","display_name":"inappropriate prescribing","score":0.5720000267028809},{"id":"https://openalex.org/keywords/national-reporting-and-learning-system","display_name":"National Reporting and Learning System","score":0.7419999837875366},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.7519999742507935},{"id":"https://openalex.org/keywords/anticoagulation","display_name":"anticoagulation","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9610400199890137},{"id":"https://openalex.org/C2776265017","wikidata":"https://www.wikidata.org/wiki/Q220570","display_name":"Pulmonary embolism","level":2,"score":0.7281825542449951},{"id":"https://openalex.org/C2776884760","wikidata":"https://www.wikidata.org/wiki/Q2750727","display_name":"Low molecular weight heparin","level":3,"score":0.72336745262146},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.47454580664634705},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.4300844669342041},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.42032167315483093},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.4023361802101135},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3252597451210022},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1136/thoraxjnl-2011-201054c.10","doi":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","is_oa":true,"landing_page_url":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","pdf_url":"https://thorax.bmj.com/content/thoraxjnl/66/Suppl_4/A70.3.full.pdf","source":{"id":"https://openalex.org/S106546978","display_name":"Thorax","issn_l":"0040-6376","issn":["0040-6376","1468-3296"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"journal-article"},{"id":"pmh:oai:open-archive.highwire.org:thoraxjnl:66/Suppl_4/A70-c","doi":null,"is_oa":false,"landing_page_url":"http://thorax.bmj.com/cgi/content/short/66/Suppl_4/A70-c","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1136/thoraxjnl-2011-201054c.10","doi":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","is_oa":true,"landing_page_url":"https://doi.org/10.1136/thoraxjnl-2011-201054c.10","pdf_url":"https://thorax.bmj.com/content/thoraxjnl/66/Suppl_4/A70.3.full.pdf","source":{"id":"https://openalex.org/S106546978","display_name":"Thorax","issn_l":"0040-6376","issn":["0040-6376","1468-3296"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2321037082.pdf","grobid_xml":"https://content.openalex.org/works/W2321037082.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2753140432","https://openalex.org/W2168376961","https://openalex.org/W2005528715","https://openalex.org/W2046669255","https://openalex.org/W2129128350","https://openalex.org/W2408512856","https://openalex.org/W2092748590","https://openalex.org/W78916690","https://openalex.org/W1985388971","https://openalex.org/W2344707894"],"abstract_inverted_index":{"Background":[0],"National":[1],"Patients":[2],"Safety":[3],"Agency":[4],"(NPSA)":[5],"issued":[6],"a":[7,67,83],"statement":[8],"in":[9,79,96,134,203,230],"July":[10],"2010":[11,103],"highlighting":[12],"the":[13,17,58,72,174,247],"risks":[14],"associated":[15,50,76,251],"with":[16,51,77,82,119,252],"prescription":[18,52,254],"of":[19,26,53,74,85,116,131,136,140,173,196,216,222,249,255],"low":[20],"molecular":[21],"weight":[22,188],"Heparins":[23],"(LMWHs).":[24],"Evidence":[25],"harm":[27,49,75,250],"has":[28,239],"been":[29],"reported":[30],"due":[31],"to":[32,38,70,180,245],"dosing":[33],"errors":[34],"caused":[35],"by":[36],"failure":[37],"weigh":[39],"patients":[40,80,91,117,149,161,175,185,217],"and":[41,61,122,190],"calculate":[42],"creatinine":[43],"clearance.":[44],"Aim":[45],"We":[46,65],"hypothesised":[47],"that":[48],"LMWHs":[54,78],"is":[55],"underreported":[56],"on":[57],"national":[59],"reporting":[60],"learning":[62],"system":[63],"(NRLS).":[64],"performed":[66],"retrospective":[68],"study":[69,238],"evaluate":[71,246],"frequency":[73,248],"admitted":[81],"suspicion":[84],"pulmonary":[86,164],"embolism":[87],"(PE).":[88],"Results":[89],"70":[90],"investigated":[92],"for":[93,157],"suspected":[94],"PE":[95],"an":[97,167],"acute":[98],"teaching":[99],"hospital":[100],"during":[101],"September":[102],"were":[104,177],"reviewed.":[105],"Mean":[106],"age":[107],"58":[108],"years":[109],"(median":[110],"61),":[111],"60%":[112],"female.":[113],"The":[114,171],"majority":[115,172],"presented":[118],"breathlessness":[120],"(64%)":[121],"pleuritic":[123],"chest":[124],"pain":[125],"(54%).":[126],"There":[127],"was":[128,200,228],"no":[129,194],"documentation":[130,195],"clinical":[132,144],"probability":[133,145],"69%":[135],"notes,":[137],"however":[138],"73%":[139],"imaging":[141],"requests":[142],"had":[143,162,186,193,208],"scores":[146],"recorded.":[147],"Eight":[148],"(26%)":[150],"did":[151],"not":[152],"have":[153],"any":[154,231],"risk":[155],"factors":[156],"venous":[158],"thrombo-embolism.":[159],"Four":[160],"CT":[163],"angiogram":[165],"following":[166],"inconclusive":[168],"perfusion":[169],"scan.":[170],"(70%)":[176],"weighed":[178],"prior":[179],"prescribing":[181],"LMWH.":[182,223,256],"Five":[183],"(7%)":[184],"their":[187,209],"estimated":[189],"14":[191],"(20%)":[192],"weight.":[197],"Creatinine":[198],"clearance":[199],"<30":[201],"ml/min":[202],"three":[204],"patients,":[205],"one":[206],"patient":[207],"LMWH":[210,225],"adjusted":[211],"accordingly.":[212],"More":[213],"than":[214],"half":[215],"(53%)":[218],"received":[219],"incorrect":[220,253],"dose":[221],"No":[224],"related":[226],"complication":[227],"recorded":[229],"patient.":[232],"Conclusion":[233],"This":[234],"small":[235],"cross":[236],"sectional":[237],"limitations.":[240],"Larger":[241],"studies":[242],"are":[243],"needed":[244]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
