{"id":"https://openalex.org/W2320992159","doi":"https://doi.org/10.1038/icb.1995.89","title":"Role of the PS integrins in Drosophila development","display_name":"Role of the PS integrins in Drosophila development","publication_year":1995,"publication_date":"1995-12-01","ids":{"openalex":"https://openalex.org/W2320992159","doi":"https://doi.org/10.1038/icb.1995.89","mag":"2320992159","pmid":"https://pubmed.ncbi.nlm.nih.gov/8713479"},"language":"en","primary_location":{"id":"doi:10.1038/icb.1995.89","doi":"https://doi.org/10.1038/icb.1995.89","is_oa":false,"landing_page_url":"https://doi.org/10.1038/icb.1995.89","pdf_url":null,"source":{"id":"https://openalex.org/S41617351","display_name":"Immunology and Cell Biology","issn_l":"0004-945X","issn":["0004-945X","0818-9641","1440-1711"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunology & Cell Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019083735","display_name":"Danny L. Brower","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"DANNY L BROWER","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721, USA","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112778138","display_name":"M. Brabant","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MARC C BRABANT","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000590974","display_name":"Thomas A. Bunch","orcid":"https://orcid.org/0000-0002-6237-1427","observed_orcids":["https://orcid.org/0000-0002-6237-1427"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"THOMAS A BUNCH","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":0.0952,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.25,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"73","issue":"6","first_page":"558","last_page":"564"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila","score":0.7239999771118164},{"id":"https://openalex.org/keywords/extracellular-matrix-receptors","display_name":"extracellular matrix receptors","score":0.9330000281333923},{"id":"https://openalex.org/keywords/embryonic-morphogenesis","display_name":"embryonic morphogenesis","score":0.7599999904632568},{"id":"https://openalex.org/keywords/wing-morphogenesis","display_name":"wing morphogenesis","score":0.5529999732971191},{"id":"https://openalex.org/keywords/genetic-mosaicism","display_name":"genetic mosaicism","score":0.7450000047683716},{"id":"https://openalex.org/keywords/cell-spreading","display_name":"cell spreading","score":0.47200000286102295},{"id":"https://openalex.org/keywords/integrin-ligands","display_name":"integrin ligands","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.9296450614929199},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7338564395904541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6440749168395996},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.6072795391082764},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.5840165615081787},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.47446686029434204},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4276800751686096},{"id":"https://openalex.org/C119524353","wikidata":"https://www.wikidata.org/wiki/Q5145908","display_name":"Collagen receptor","level":4,"score":0.4162241816520691},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.33171546459198},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2890905737876892},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20497927069664001}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009024","descriptor_name":"Morphogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011679","descriptor_name":"Pupa","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D011679","descriptor_name":"Pupa","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011679","descriptor_name":"Pupa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014170","descriptor_name":"Transformation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014921","descriptor_name":"Wings, Animal","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D014921","descriptor_name":"Wings, Animal","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D014921","descriptor_name":"Wings, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D039001","descriptor_name":"Integrin alpha Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/icb.1995.89","doi":"https://doi.org/10.1038/icb.1995.89","is_oa":false,"landing_page_url":"https://doi.org/10.1038/icb.1995.89","pdf_url":null,"source":{"id":"https://openalex.org/S41617351","display_name":"Immunology and Cell Biology","issn_l":"0004-945X","issn":["0004-945X","0818-9641","1440-1711"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunology & Cell Biology","raw_type":"journal-article"},{"id":"pmid:8713479","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8713479","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunology and cell biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G223908282","display_name":"Structure/Function Studies of the Integrin","funder_award_id":"R01GM042474","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W121728055","https://openalex.org/W1581907742","https://openalex.org/W1882780242","https://openalex.org/W1883735868","https://openalex.org/W1970656914","https://openalex.org/W1971525809","https://openalex.org/W2001552205","https://openalex.org/W2018947638","https://openalex.org/W2019352751","https://openalex.org/W2029231027","https://openalex.org/W2036408841","https://openalex.org/W2042371710","https://openalex.org/W2049162644","https://openalex.org/W2052436795","https://openalex.org/W2057833663","https://openalex.org/W2067994205","https://openalex.org/W2080321447","https://openalex.org/W2080592483","https://openalex.org/W2089043901","https://openalex.org/W2092683568","https://openalex.org/W2099300824","https://openalex.org/W2111778285","https://openalex.org/W2123168425","https://openalex.org/W2146779790","https://openalex.org/W2147517839","https://openalex.org/W2170852571","https://openalex.org/W2237461794","https://openalex.org/W2238147653","https://openalex.org/W2241971323","https://openalex.org/W2272180841"],"related_works":["https://openalex.org/W34561060","https://openalex.org/W7020552404","https://openalex.org/W2588716588","https://openalex.org/W2080592483","https://openalex.org/W2170852571","https://openalex.org/W1588176153","https://openalex.org/W2188990683","https://openalex.org/W2048553981","https://openalex.org/W2049162644","https://openalex.org/W2272180841"],"abstract_inverted_index":{"The":[0],"PS1":[1,53],"and":[2,11,37,54,60,73,100,131,134],"PS2":[3,55],"integrins":[4,30,81,121,144],"of":[5,9,76,88,91,102],"Drosophila":[6,47],"are":[7,31,38,82,122,145],"heterodimers":[8],"alphaPS1betaPS":[10],"alphaPS2betaPS":[12],"subunits,":[13],"respectively,":[14],"with":[15],"very":[16],"strong":[17],"structural":[18],"similarity":[19],"to":[20,41,96,125,152],"vertebrate":[21,42],"integrins.":[22,43],"Cell":[23],"transfection":[24],"experiments":[25],"indicate":[26,78],"that":[27,79,138],"the":[28,74,85,118,127,143],"PS":[29,80],"receptors":[32],"for":[33,52,84],"extracellular":[34],"matrix":[35],"components":[36],"functionally":[39],"analogous":[40],"Matrix":[44],"ligands":[45],"from":[46],"tissues":[48],"have":[49,70,114],"been":[50,71,115],"identified":[51],"integrins,":[56],"using":[57],"transformed":[58],"cells":[59],"a":[61,89,153],"cell-spreading":[62],"assay.":[63],"Mutations":[64],"in":[65,110,139],"all":[66],"three":[67],"subunit":[68],"genes":[69],"identified,":[72],"phenotypes":[75],"mutants":[77],"required":[83,124],"proper":[86],"morphogenesis":[87,112],"number":[90],"embryonic":[92],"tissues.":[93],"Using":[94],"methods":[95],"produce":[97],"genetic":[98],"mosaics":[99],"transformation":[101],"integrin":[103,108],"transgenes":[104],"into":[105],"whole":[106],"animals,":[107],"functions":[109],"adult":[111],"also":[113],"examined.":[116],"In":[117],"pupal":[119,141],"wing,":[120],"critically":[123],"maintain":[126],"connection":[128],"between":[129],"dorsal":[130],"ventral":[132],"epithelia,":[133],"recent":[135],"results":[136],"suggest":[137],"early":[140],"development,":[142],"acting":[146],"as":[147,150],"specific":[148],"receptors,":[149],"opposed":[151],"non-specific":[154],"cell-matrix":[155],"glue.":[156]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}