{"id":"https://openalex.org/W2320091069","doi":"https://doi.org/10.1253/circj.cj-15-1309","title":"Native T1 Relaxation Time and Extracellular Volume Fraction as Accurate Markers of Diffuse Myocardial Fibrosis in Heart Valve Disease \u2013 Comparison With Targeted Left Ventricular Myocardial Biopsy \u2013","display_name":"Native T1 Relaxation Time and Extracellular Volume Fraction as Accurate Markers of Diffuse Myocardial Fibrosis in Heart Valve Disease \u2013 Comparison With Targeted Left Ventricular Myocardial Biopsy \u2013","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2320091069","doi":"https://doi.org/10.1253/circj.cj-15-1309","mag":"2320091069","pmid":"https://pubmed.ncbi.nlm.nih.gov/26984717"},"language":"en","primary_location":{"id":"doi:10.1253/circj.cj-15-1309","doi":"https://doi.org/10.1253/circj.cj-15-1309","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.cj-15-1309","pdf_url":"https://www.jstage.jst.go.jp/article/circj/80/5/80_CJ-15-1309/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/circj/80/5/80_CJ-15-1309/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078008872","display_name":"Radka Ko\u010dkov\u00e1","orcid":"https://orcid.org/0000-0002-6645-0245","observed_orcids":["https://orcid.org/0000-0002-6645-0245"]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]},{"id":"https://openalex.org/I4210166371","display_name":"Czech Academy of Sciences, Institute of Physiology","ror":"https://ror.org/05xw0ep96","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210166371"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Radka Kockova","raw_affiliation_strings":["Department of Cardiology, Institute for Clinical and Experimental Medicine","Institute of Physiology, Academy of Sciences of the Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]},{"raw_affiliation_string":"Institute of Physiology, Academy of Sciences of the Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210166371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102836727","display_name":"Petr Ka\u010der","orcid":"https://orcid.org/0000-0002-1662-5828","observed_orcids":["https://orcid.org/0000-0002-1662-5828"]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Petr Kacer","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109262901","display_name":"Jan Pirk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Jan Pirk","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101694789","display_name":"Ji\u0159\u00ed Mal\u00fd","orcid":"https://orcid.org/0000-0002-7863-245X","observed_orcids":["https://orcid.org/0000-0002-7863-245X"]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Jiri Maly","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031631363","display_name":"Lucie S\u00fakupov\u00e1","orcid":"https://orcid.org/0000-0002-6641-8288","observed_orcids":["https://orcid.org/0000-0002-6641-8288"]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Lucie Sukupova","raw_affiliation_strings":["Department of Cardiology, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064336988","display_name":"Viktor \u0160ikula","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Viktor Sikula","raw_affiliation_strings":["Department of Cardiology, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087240557","display_name":"Martin Kotr\u010d","orcid":"https://orcid.org/0000-0002-2068-0379","observed_orcids":["https://orcid.org/0000-0002-2068-0379"]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Martin Kotrc","raw_affiliation_strings":["Department of Cardiology, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072313319","display_name":"Lucia Barciakova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Lucia Barciakova","raw_affiliation_strings":["Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056807156","display_name":"Eva Honsov\u00e1","orcid":"https://orcid.org/0000-0002-1625-1993","observed_orcids":["https://orcid.org/0000-0002-1625-1993"]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Eva Honsova","raw_affiliation_strings":["Clinical and Transplant Pathology Department, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Transplant Pathology Department, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048335799","display_name":"Marek Mal\u00fd","orcid":"https://orcid.org/0000-0002-5930-563X","observed_orcids":["https://orcid.org/0000-0002-5930-563X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marek Maly","raw_affiliation_strings":["National Institute of Public Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Public Health","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073033425","display_name":"Josef Kautzner","orcid":"https://orcid.org/0000-0002-1632-6182","observed_orcids":["https://orcid.org/0000-0002-1632-6182"]},"institutions":[{"id":"https://openalex.org/I4210127955","display_name":"Institute of Clinical and Experimental Medicine","ror":"https://ror.org/036zr1b90","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210127955"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Josef Kautzner","raw_affiliation_strings":["Department of Cardiology, Institute for Clinical and Experimental Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Institute for Clinical and Experimental Medicine","institution_ids":["https://openalex.org/I4210127955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089127172","display_name":"David Sedmera","orcid":"https://orcid.org/0000-0002-6828-3671","observed_orcids":["https://orcid.org/0000-0002-6828-3671"]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I21250087","display_name":"Charles University","ror":"https://ror.org/024d6js02","country_code":"CZ","type":"education","lineage":["https://openalex.org/I21250087"]},{"id":"https://openalex.org/I4210166371","display_name":"Czech Academy of Sciences, Institute of Physiology","ror":"https://ror.org/05xw0ep96","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210166371"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"David Sedmera","raw_affiliation_strings":["First Faculty of Medicine, Institute of Anatomy, Charles University in Prague","Institute of Physiology, Academy of Sciences of the Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Faculty of Medicine, Institute of Anatomy, Charles University in Prague","institution_ids":["https://openalex.org/I21250087"]},{"raw_affiliation_string":"Institute of Physiology, Academy of Sciences of the Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210166371"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077892878","display_name":"Martin P\u011bni\u010dka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101486","display_name":"Onze Lieve Vrouwziekenhuis Hospital","ror":"https://ror.org/00zrfhe30","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210101486"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Martin Penicka","raw_affiliation_strings":["OLV Clinic, Cardiovascular Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OLV Clinic, Cardiovascular Center","institution_ids":["https://openalex.org/I4210101486"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.5315,"has_fulltext":true,"cited_by_count":57,"citation_normalized_percentile":{"value":0.95834344,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"80","issue":"5","first_page":"1202","last_page":"1209"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.7782999873161316,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.7782999873161316,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.08240000158548355,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.050700001418590546,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffuse-myocardial-fibrosis","display_name":"diffuse myocardial fibrosis","score":0.9200000166893005},{"id":"https://openalex.org/keywords/extracellular-volume-fraction","display_name":"extracellular volume fraction","score":0.9430000185966492},{"id":"https://openalex.org/keywords/valvular-heart-disease","display_name":"valvular heart disease","score":0.828000009059906},{"id":"https://openalex.org/keywords/aortic-stenosis","display_name":"aortic stenosis","score":0.9580000042915344},{"id":"https://openalex.org/keywords/cardiac-magnetic-resonance-t1-mapping","display_name":"cardiac magnetic resonance T1 mapping","score":0.8370000123977661},{"id":"https://openalex.org/keywords/myocardial-collagen","display_name":"myocardial collagen","score":0.8700000047683716},{"id":"https://openalex.org/keywords/left-ventricular-mass","display_name":"left ventricular mass","score":0.8299999833106995},{"id":"https://openalex.org/keywords/valvular-regurgitation","display_name":"valvular regurgitation","score":0.9259999990463257}],"concepts":[{"id":"https://openalex.org/C3018763269","wikidata":"https://www.wikidata.org/wiki/Q5038318","display_name":"Myocardial fibrosis","level":3,"score":0.8084891438484192},{"id":"https://openalex.org/C2779740085","wikidata":"https://www.wikidata.org/wiki/Q2397680","display_name":"Interventricular septum","level":3,"score":0.8024503588676453},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7671226263046265},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6512738466262817},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5673123598098755},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.4879576563835144},{"id":"https://openalex.org/C2780168065","wikidata":"https://www.wikidata.org/wiki/Q1930043","display_name":"Regurgitation (circulation)","level":2,"score":0.45361000299453735},{"id":"https://openalex.org/C2779745306","wikidata":"https://www.wikidata.org/wiki/Q616087","display_name":"Aortic valve regurgitation","level":3,"score":0.45102590322494507},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.43227308988571167},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.41871851682662964},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1253/circj.cj-15-1309","doi":"https://doi.org/10.1253/circj.cj-15-1309","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.cj-15-1309","pdf_url":"https://www.jstage.jst.go.jp/article/circj/80/5/80_CJ-15-1309/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},{"id":"pmid:26984717","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26984717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation journal : official journal of the Japanese Circulation Society","raw_type":"Comparative Study"},{"id":"pmh:oai:asep.lib.cas.cz:CavUnEpca/0464970","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11104/0263769","pdf_url":null,"source":{"id":"https://openalex.org/S7407055266","display_name":"ASEP","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1253/circj.cj-15-1309","doi":"https://doi.org/10.1253/circj.cj-15-1309","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.cj-15-1309","pdf_url":"https://www.jstage.jst.go.jp/article/circj/80/5/80_CJ-15-1309/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7699999809265137,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G5932090947","display_name":"Epigenetic factors in myocardial morphogenesis","funder_award_id":"GAP302/11/1308","funder_id":"https://openalex.org/F4320321006","funder_display_name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky"}],"funders":[{"id":"https://openalex.org/F4320321006","display_name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","ror":"https://ror.org/01pv73b02"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2320091069.pdf","grobid_xml":"https://content.openalex.org/works/W2320091069.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W195414628","https://openalex.org/W1579742180","https://openalex.org/W1781922193","https://openalex.org/W1948348644","https://openalex.org/W1967965542","https://openalex.org/W1974432041","https://openalex.org/W1979384626","https://openalex.org/W1984075087","https://openalex.org/W1986622667","https://openalex.org/W1988866039","https://openalex.org/W2001926365","https://openalex.org/W2002993325","https://openalex.org/W2005673278","https://openalex.org/W2022544791","https://openalex.org/W2027082110","https://openalex.org/W2039057919","https://openalex.org/W2046749165","https://openalex.org/W2049455628","https://openalex.org/W2070435023","https://openalex.org/W2080478397","https://openalex.org/W2081159589","https://openalex.org/W2085786241","https://openalex.org/W2090668448","https://openalex.org/W2099194107","https://openalex.org/W2099540110","https://openalex.org/W2100071934","https://openalex.org/W2102294852","https://openalex.org/W2102830752","https://openalex.org/W2111161258","https://openalex.org/W2111896397","https://openalex.org/W2117892932","https://openalex.org/W2121179755","https://openalex.org/W2133554780","https://openalex.org/W2134708419","https://openalex.org/W2146051421","https://openalex.org/W2146213208","https://openalex.org/W2150691023","https://openalex.org/W2155014420","https://openalex.org/W2159285706","https://openalex.org/W2164132423","https://openalex.org/W2165159075","https://openalex.org/W2168915540","https://openalex.org/W2171820373","https://openalex.org/W2171941165","https://openalex.org/W2614788422","https://openalex.org/W4210285953"],"related_works":["https://openalex.org/W2422726611","https://openalex.org/W2394983069","https://openalex.org/W1981286570","https://openalex.org/W1606373491","https://openalex.org/W2049710580","https://openalex.org/W3033827510","https://openalex.org/W2761036856","https://openalex.org/W2317553116","https://openalex.org/W2105638059","https://openalex.org/W1998021066"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,45,75,121,132,176],"aim":[2],"of":[3,30,49,123,135,204],"our":[4],"study":[5,46],"was":[6,79,105,126,138],"to":[7,99,171],"investigate":[8],"the":[9,12,28,82,92,110,117,154,166],"relationship":[10],"between":[11],"cardiac":[13],"magnetic":[14],"resonance":[15],"(CMR)-derived":[16],"native":[17,141,177],"T1":[18,76,118,142,178,190],"relaxation":[19,77,143,179,191],"time":[20,78,144,180,192],"and":[21,27,87,156,193],"myocardial":[22,32,37,102,124,136],"extracellular":[23],"volume":[24],"(ECV)":[25],"fraction":[26],"extent":[29],"diffuse":[31],"fibrosis":[33],"(DMF)":[34],"on":[35],"targeted":[36],"left":[38],"ventricular":[39],"(LV)":[40],"biopsy.":[41],"METHODS":[42],"AND":[43],"RESULTS:":[44],"population":[47],"consisted":[48],"40":[50],"patients":[51],"(age":[52],"63\u00b18":[53],"years,":[54],"65%":[55],"male)":[56],"undergoing":[57],"valve":[58,72],"and/or":[59],"ascending":[60],"aorta":[61],"surgery":[62,108],"for":[63],"severe":[64,173],"aortic":[65],"stenosis":[66],"(77.5%),":[67],"root":[68],"dilatation":[69],"(7.5%)":[70],"or":[71],"regurgitation":[73],"(15%).":[74],"assessed":[80],"in":[81],"basal":[83,111],"interventricular":[84,112],"septum":[85],"pre-":[86],"10-min":[88],"post-contrast":[89],"administration":[90,200],"using":[91,128],"modified":[93],"Look-Locker":[94],"Inversion":[95],"recovery":[96],"sequence":[97],"prior":[98],"surgery.":[100],"LV":[101,185],"biopsy":[103],"specimen":[104],"obtained":[106],"during":[107],"from":[109],"septal":[113],"segment":[114],"matched":[115],"with":[116,145,158,184],"mapping":[119],"assessment.":[120],"percentage":[122,134],"collagen":[125,137],"quantified":[127],"picrosirius":[129],"red":[130],"staining.":[131],"average":[133],"22.0\u00b114.8%.":[139],"Both":[140],"cutoff":[146,159],"value":[147,160],"\u22651,010":[148],"ms":[149],"(sensitivity=90%,":[150],"specificity=73%,":[151],"area":[152,164],"under":[153,165],"curve=0.82)":[155],"ECV":[157,194],"\u22650.32":[161],"(sensitivity=80%,":[162],"specificity=90%,":[163],"curve=0.85)":[167],"showed":[168,181],"high":[169],"accuracy":[170],"identify":[172],"(>30%)":[174],"DMF.":[175,205],"significant":[182],"correlation":[183],"mass":[186],"(P<0.01).":[187],"CONCLUSIONS:":[188],"Native":[189],"at":[195],"10":[196],"min":[197],"after":[198],"contrast":[199],"are":[201],"accurate":[202],"markers":[203],"(Circ":[206],"J":[207],"2016;":[208],"80:":[209],"1202-1209).":[210]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":7}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2025-10-10T00:00:00"}