{"id":"https://openalex.org/W2319944451","doi":"https://doi.org/10.1021/mp300041k","title":"Dendrimer-Driven Neurotrophin Expression Differs in Temporal Patterns between Rodent and Human Stem Cells","display_name":"Dendrimer-Driven Neurotrophin Expression Differs in Temporal Patterns between Rodent and Human Stem Cells","publication_year":2012,"publication_date":"2012-04-05","ids":{"openalex":"https://openalex.org/W2319944451","doi":"https://doi.org/10.1021/mp300041k","mag":"2319944451","pmid":"https://pubmed.ncbi.nlm.nih.gov/22480259"},"language":"en","primary_location":{"id":"doi:10.1021/mp300041k","doi":"https://doi.org/10.1021/mp300041k","is_oa":false,"landing_page_url":"https://doi.org/10.1021/mp300041k","pdf_url":null,"source":{"id":"https://openalex.org/S204562082","display_name":"Molecular Pharmaceutics","issn_l":"1543-8384","issn":["1543-8384","1543-8392"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmaceutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064113702","display_name":"Antos Shakhbazau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Antos Shakhbazau","raw_affiliation_strings":["Department\rof Clinical Neurosciences,\rFaculty of Medicine, University of Calgary, Calgary, Canada","Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Clinical Neurosciences,\rFaculty of Medicine, University of Calgary, Calgary, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004241837","display_name":"Dzmitry Shcharbin","orcid":"https://orcid.org/0000-0002-1414-4465","observed_orcids":["https://orcid.org/0000-0002-1414-4465"]},"institutions":[{"id":"https://openalex.org/I151823869","display_name":"National Academy of Sciences of Belarus","ror":"https://ror.org/02j8pe645","country_code":"BY","type":"government","lineage":["https://openalex.org/I151823869"]},{"id":"https://openalex.org/I4210094316","display_name":"Institute of Biophysics and Cell Engineering","ror":"https://ror.org/00q3psk33","country_code":"BY","type":"facility","lineage":["https://openalex.org/I151823869","https://openalex.org/I4210094316","https://openalex.org/I4210158638"]}],"countries":["BY"],"is_corresponding":false,"raw_author_name":"Dzmitry Shcharbin","raw_affiliation_strings":["Institute\rof Biophysics and Cell\rEngineering, National Academy of Sciences of Belarus, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute\rof Biophysics and Cell\rEngineering, National Academy of Sciences of Belarus, Minsk, Belarus","institution_ids":["https://openalex.org/I151823869","https://openalex.org/I4210094316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079636049","display_name":"Ihar Seviaryn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ihar Seviaryn","raw_affiliation_strings":["Republic Centre for Hematology and Transfusiology, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republic Centre for Hematology and Transfusiology, Minsk, Belarus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109105016","display_name":"Natalya V. Goncharova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Natalya Goncharova","raw_affiliation_strings":["Republic Centre for Hematology and Transfusiology, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republic Centre for Hematology and Transfusiology, Minsk, Belarus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003737860","display_name":"Svetlana M. Kosmacheva","orcid":"https://orcid.org/0000-0002-1617-8845","observed_orcids":["https://orcid.org/0000-0002-1617-8845"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Svetlana Kosmacheva","raw_affiliation_strings":["Republic Centre for Hematology and Transfusiology, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republic Centre for Hematology and Transfusiology, Minsk, Belarus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111708305","display_name":"Mihail Potapnev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mihail Potapnev","raw_affiliation_strings":["Republic Centre for Hematology and Transfusiology, Minsk, Belarus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republic Centre for Hematology and Transfusiology, Minsk, Belarus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058193488","display_name":"Maria J Bryszewska","orcid":"https://orcid.org/0000-0003-4676-3743","observed_orcids":["https://orcid.org/0000-0003-4676-3743"]},"institutions":[{"id":"https://openalex.org/I34250744","display_name":"University of \u0141\u00f3d\u017a","ror":"https://ror.org/05cq64r17","country_code":"PL","type":"education","lineage":["https://openalex.org/I34250744"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Maria Bryszewska","raw_affiliation_strings":["Department of General Biophysics, University of Lodz, Lodz, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Biophysics, University of Lodz, Lodz, Poland","institution_ids":["https://openalex.org/I34250744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061317490","display_name":"Ranjan Kumar","orcid":"https://orcid.org/0000-0002-7002-1267","observed_orcids":["https://orcid.org/0000-0002-7002-1267"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ranjan Kumar","raw_affiliation_strings":["Department\rof Clinical Neurosciences,\rFaculty of Medicine, University of Calgary, Calgary, Canada","Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada","Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Clinical Neurosciences,\rFaculty of Medicine, University of Calgary, Calgary, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053114491","display_name":"Jeffrey Biernaskie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jeffrey Biernaskie","raw_affiliation_strings":["Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada","Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110269610","display_name":"Rajiv Midha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I4405260330","display_name":"Hotchkiss Brain Institute","ror":"https://ror.org/03k51z204","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Rajiv Midha","raw_affiliation_strings":["Department\rof Clinical Neurosciences,\rFaculty of Medicine, University of Calgary, Calgary, Canada","Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Clinical Neurosciences,\rFaculty of Medicine, University of Calgary, Calgary, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Hotchkiss\rBrain Institute, University of Calgary,\rCalgary, Canada","institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5064113702"],"corresponding_institution_ids":["https://openalex.org/I168635309","https://openalex.org/I4405260330"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.4499,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.87948944,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"9","issue":"5","first_page":"1521","last_page":"1528"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pamam-dendrimers","display_name":"PAMAM dendrimers","score":0.9919999837875366},{"id":"https://openalex.org/keywords/nonviral-gene-delivery","display_name":"non-viral gene delivery","score":0.8809999823570251},{"id":"https://openalex.org/keywords/neurotrophin-expression","display_name":"neurotrophin expression","score":0.7860000133514404},{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":0.949999988079071},{"id":"https://openalex.org/keywords/neurotrophin-3","display_name":"neurotrophin-3","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.984000027179718},{"id":"https://openalex.org/keywords/schwann-cells","display_name":"Schwann cells","score":0.9700000286102295},{"id":"https://openalex.org/keywords/transient-expression","display_name":"transient expression","score":0.5950000286102295},{"id":"https://openalex.org/keywords/plasmid-dna-delivery","display_name":"plasmid DNA delivery","score":0.7099999785423279},{"id":"https://openalex.org/keywords/autologous-stem-cell-therapy","display_name":"autologous stem cell therapy","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C92020748","wikidata":"https://www.wikidata.org/wiki/Q420457","display_name":"Neurotrophin","level":3,"score":0.7656493186950684},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6989364624023438},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6628141403198242},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6533889174461365},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.6139779686927795},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.555814802646637},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.4517081677913666},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3549414575099945},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10834822058677673},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08987930417060852},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06999194622039795}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009414","descriptor_name":"Nerve Growth Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009414","descriptor_name":"Nerve Growth Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020219","descriptor_name":"Chondrogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020219","descriptor_name":"Chondrogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020933","descriptor_name":"Neurotrophin 3","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020933","descriptor_name":"Neurotrophin 3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050091","descriptor_name":"Dendrimers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/mp300041k","doi":"https://doi.org/10.1021/mp300041k","is_oa":false,"landing_page_url":"https://doi.org/10.1021/mp300041k","pdf_url":null,"source":{"id":"https://openalex.org/S204562082","display_name":"Molecular Pharmaceutics","issn_l":"1543-8384","issn":["1543-8384","1543-8392"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmaceutics","raw_type":"journal-article"},{"id":"pmid:22480259","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22480259","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular pharmaceutics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2401877109","display_name":null,"funder_award_id":"#163322","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"}],"funders":[{"id":"https://openalex.org/F4320310537","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39"},{"id":"https://openalex.org/F4320310917","display_name":"Hotchkiss Brain Institute, University of Calgary","ror":"https://ror.org/03yjb2x39"},{"id":"https://openalex.org/F4320310939","display_name":"Integra LifeSciences","ror":"https://ror.org/04qce9v53"},{"id":"https://openalex.org/F4320319927","display_name":"Alberta Innovates - Health Solutions","ror":"https://ror.org/00ynafe15"},{"id":"https://openalex.org/F4320334392","display_name":"Health Canada","ror":"https://ror.org/05p8nb362"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W1604428153","https://openalex.org/W1781764416","https://openalex.org/W1965296715","https://openalex.org/W1966235893","https://openalex.org/W1966369360","https://openalex.org/W1969278350","https://openalex.org/W1975409144","https://openalex.org/W1977608305","https://openalex.org/W1977728725","https://openalex.org/W1982302921","https://openalex.org/W1985265330","https://openalex.org/W1994645489","https://openalex.org/W1996725588","https://openalex.org/W2004168444","https://openalex.org/W2004794741","https://openalex.org/W2006276932","https://openalex.org/W2007117119","https://openalex.org/W2020901017","https://openalex.org/W2023230379","https://openalex.org/W2026435283","https://openalex.org/W2026938196","https://openalex.org/W2027022352","https://openalex.org/W2033705147","https://openalex.org/W2034700594","https://openalex.org/W2037327932","https://openalex.org/W2040426333","https://openalex.org/W2044693977","https://openalex.org/W2057536565","https://openalex.org/W2060528855","https://openalex.org/W2065624367","https://openalex.org/W2074706210","https://openalex.org/W2076401171","https://openalex.org/W2078963996","https://openalex.org/W2081321708","https://openalex.org/W2081805576","https://openalex.org/W2082312462","https://openalex.org/W2083271723","https://openalex.org/W2083776533","https://openalex.org/W2084365180","https://openalex.org/W2084653857","https://openalex.org/W2088134619","https://openalex.org/W2089720406","https://openalex.org/W2095257528","https://openalex.org/W2098942729","https://openalex.org/W2101578637","https://openalex.org/W2101717161","https://openalex.org/W2112582221","https://openalex.org/W2112917272","https://openalex.org/W2125674387","https://openalex.org/W2127142378","https://openalex.org/W2129713716","https://openalex.org/W2136159111","https://openalex.org/W2141310245","https://openalex.org/W2143048986","https://openalex.org/W2145018993","https://openalex.org/W2147372469","https://openalex.org/W2149915061","https://openalex.org/W2152489651","https://openalex.org/W2158998850","https://openalex.org/W2161014670","https://openalex.org/W2186821906","https://openalex.org/W2313378998","https://openalex.org/W2333602387","https://openalex.org/W4230909310","https://openalex.org/W4234076530"],"related_works":["https://openalex.org/W1994645489","https://openalex.org/W2033705147","https://openalex.org/W1990055281","https://openalex.org/W2955544437","https://openalex.org/W2094472882","https://openalex.org/W3179640364","https://openalex.org/W2011626437","https://openalex.org/W3145001639","https://openalex.org/W3206190542","https://openalex.org/W2572893270"],"abstract_inverted_index":{"This":[0],"study":[1],"reports":[2],"the":[3,51,62,126],"use":[4],"of":[5,53,129],"a":[6,83,118],"nonviral":[7],"expression":[8,42,54,69,74,92,112,116],"system":[9],"based":[10],"on":[11],"polyamidoamine":[12],"dendrimers":[13,28],"for":[14,34,97],"time-restricted":[15],"neurotrophin":[16,115],"overproduction":[17],"in":[18,43,75,109],"mesenchymal":[19,77],"stem":[20,48,78,132,135],"cells":[21,79,133],"and":[22,46,50,67,121,134],"skin":[23],"precursor-derived":[24],"Schwann":[25],"cells.":[26,90,139],"The":[27],"were":[29,55,71,101],"used":[30],"to":[31,88,104,124],"deliver":[32],"plasmids":[33],"brain-derived":[35],"neurotrophic":[36],"factor":[37],"(BDNF)":[38],"or":[39],"neurotrophin-3":[40],"(NT-3)":[41],"both":[44],"rodent":[45,89],"human":[47,76],"cells,":[49],"timelines":[52],"studied.":[56],"We":[57],"have":[58],"found":[59],"that,":[60],"despite":[61],"fact":[63],"that":[64],"transfection":[65],"efficiencies":[66],"protein":[68],"levels":[70],"comparable,":[72],"dendrimer-driven":[73],"was":[80],"characterized":[81],"by":[82],"more":[84],"rapid":[85],"decline":[86],"compared":[87],"Transient":[91],"systems":[93],"can":[94],"be":[95],"beneficial":[96],"some":[98],"neurotrophins,":[99],"which":[100],"earlier":[102],"reported":[103],"cause":[105],"unwanted":[106],"side":[107],"effects":[108],"virus-based":[110],"long-term":[111],"models.":[113],"Nonviral":[114],"is":[117],"biologically":[119],"safe":[120],"accessible":[122],"alternative":[123],"increase":[125],"therapeutic":[127],"potential":[128],"autologous":[130],"adult":[131],"cell-derived":[136],"functional":[137],"differentiated":[138]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
