{"id":"https://openalex.org/W2319623974","doi":"https://doi.org/10.1021/ac501664t","title":"Asymmetric Flow Field-Flow Fractionation in the Field of Nanomedicine","display_name":"Asymmetric Flow Field-Flow Fractionation in the Field of Nanomedicine","publication_year":2014,"publication_date":"2014-05-06","ids":{"openalex":"https://openalex.org/W2319623974","doi":"https://doi.org/10.1021/ac501664t","mag":"2319623974","pmid":"https://pubmed.ncbi.nlm.nih.gov/24802650"},"language":"en","primary_location":{"id":"doi:10.1021/ac501664t","doi":"https://doi.org/10.1021/ac501664t","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac501664t","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Michael Wagner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Wagner","raw_affiliation_strings":["Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","Laboratory\rof Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]},{"raw_affiliation_string":"Laboratory\rof Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082017409","display_name":"Stephan Holzschuh","orcid":"https://orcid.org/0000-0001-8659-4070","observed_orcids":["https://orcid.org/0000-0001-8659-4070"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephan Holzschuh","raw_affiliation_strings":["Department\rof Pharmaceutical Technology, Friedrich Schiller University Jena, Lessingstrasse 8, 07743 Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Pharmaceutical Technology, Friedrich Schiller University Jena, Lessingstrasse 8, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034120978","display_name":"Anja Traeger","orcid":"https://orcid.org/0000-0001-7734-2293","observed_orcids":["https://orcid.org/0000-0001-7734-2293"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anja Traeger","raw_affiliation_strings":["Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","Laboratory\rof Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]},{"raw_affiliation_string":"Laboratory\rof Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021628349","display_name":"Alfred Fahr","orcid":"https://orcid.org/0000-0002-4876-1357","observed_orcids":["https://orcid.org/0000-0002-4876-1357"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alfred Fahr","raw_affiliation_strings":["Department\rof Pharmaceutical Technology, Friedrich Schiller University Jena, Lessingstrasse 8, 07743 Jena, Germany","Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Pharmaceutical Technology, Friedrich Schiller University Jena, Lessingstrasse 8, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]},{"raw_affiliation_string":"Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075012306","display_name":"Ulrich S. Schubert","orcid":"https://orcid.org/0000-0003-4978-4670","observed_orcids":["https://orcid.org/0000-0003-4978-4670"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Ulrich. S. Schubert","raw_affiliation_strings":["Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","Laboratory\rof Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jena\rCenter for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]},{"raw_affiliation_string":"Laboratory\rof Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075012306"],"corresponding_institution_ids":["https://openalex.org/I76198965"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.9059,"has_fulltext":false,"cited_by_count":141,"citation_normalized_percentile":{"value":0.64777328,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"86","issue":"11","first_page":"5201","last_page":"5210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12850","display_name":"Field-Flow Fractionation Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12850","display_name":"Field-Flow Fractionation Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10180","display_name":"Analytical chemistry methods development","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asymmetric-flow-field-flow-fractionation","display_name":"asymmetrical flow field-flow fractionation","score":1.0},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.8479999899864197},{"id":"https://openalex.org/keywords/macromolecule-characterization","display_name":"macromolecule characterization","score":0.6600000262260437},{"id":"https://openalex.org/keywords/colloids","display_name":"colloids","score":0.7609999775886536},{"id":"https://openalex.org/keywords/multi-angle-light-scattering","display_name":"multi-angle light scattering","score":0.7710000276565552},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.8059999942779541},{"id":"https://openalex.org/keywords/nanoparticles","display_name":"nanoparticles","score":0.8009999990463257},{"id":"https://openalex.org/keywords/micelles","display_name":"micelles","score":0.9679999947547913},{"id":"https://openalex.org/keywords/dendrimers","display_name":"dendrimers","score":0.9539999961853027},{"id":"https://openalex.org/keywords/liposomes","display_name":"liposomes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/polyplexes","display_name":"polyplexes","score":0.9940000176429749},{"id":"https://openalex.org/keywords/virus-like-particles","display_name":"virus-like particles","score":0.9990000128746033},{"id":"https://openalex.org/keywords/therapeutic-proteins","display_name":"therapeutic proteins","score":0.7570000290870667},{"id":"https://openalex.org/keywords/immunoglobulins","display_name":"immunoglobulins","score":0.8550000190734863},{"id":"https://openalex.org/keywords/membrane-type","display_name":"membrane type","score":0.7139999866485596},{"id":"https://openalex.org/keywords/buffering-effect","display_name":"buffering effect","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C16031182","wikidata":"https://www.wikidata.org/wiki/Q782281","display_name":"Field flow fractionation","level":3,"score":0.7790428400039673},{"id":"https://openalex.org/C98239406","wikidata":"https://www.wikidata.org/wiki/Q6934570","display_name":"Multiangle light scattering","level":4,"score":0.7366700172424316},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7261976003646851},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.7030366063117981},{"id":"https://openalex.org/C97428945","wikidata":"https://www.wikidata.org/wiki/Q15305109","display_name":"Fractionation","level":2,"score":0.6142037510871887},{"id":"https://openalex.org/C11432220","wikidata":"https://www.wikidata.org/wiki/Q1975334","display_name":"Dispersity","level":2,"score":0.5938913226127625},{"id":"https://openalex.org/C196503311","wikidata":"https://www.wikidata.org/wiki/Q145623","display_name":"Molar mass","level":3,"score":0.5651482939720154},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5599711537361145},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.5316467881202698},{"id":"https://openalex.org/C15083742","wikidata":"https://www.wikidata.org/wiki/Q261659","display_name":"Nanomedicine","level":3,"score":0.48987051844596863},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.4498358368873596},{"id":"https://openalex.org/C55637122","wikidata":"https://www.wikidata.org/wiki/Q903923","display_name":"Dendrimer","level":2,"score":0.4448893070220947},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.4337741732597351},{"id":"https://openalex.org/C120456961","wikidata":"https://www.wikidata.org/wiki/Q210028","display_name":"Light scattering","level":3,"score":0.3878418207168579},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3208240270614624},{"id":"https://openalex.org/C191486275","wikidata":"https://www.wikidata.org/wiki/Q210028","display_name":"Scattering","level":2,"score":0.2317790687084198},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.15408951044082642},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10145330429077148},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012542","descriptor_name":"Scattering, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016503","descriptor_name":"Drug Delivery Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031521","descriptor_name":"Fractionation, Field Flow","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D031521","descriptor_name":"Fractionation, Field Flow","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D050997","descriptor_name":"Nanomedicine","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/ac501664t","doi":"https://doi.org/10.1021/ac501664t","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac501664t","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},{"id":"pmid:24802650","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24802650","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":115,"referenced_works":["https://openalex.org/W57956218","https://openalex.org/W63890971","https://openalex.org/W207717361","https://openalex.org/W1524305523","https://openalex.org/W1525478498","https://openalex.org/W1647075334","https://openalex.org/W1964812709","https://openalex.org/W1964962540","https://openalex.org/W1967800067","https://openalex.org/W1972608002","https://openalex.org/W1974900416","https://openalex.org/W1976920802","https://openalex.org/W1978738025","https://openalex.org/W1979158597","https://openalex.org/W1979249140","https://openalex.org/W1979532891","https://openalex.org/W1981075857","https://openalex.org/W1981158098","https://openalex.org/W1982232702","https://openalex.org/W1982556374","https://openalex.org/W1986415571","https://openalex.org/W1986720534","https://openalex.org/W1989230986","https://openalex.org/W1989239770","https://openalex.org/W1989331907","https://openalex.org/W1992630762","https://openalex.org/W1994158992","https://openalex.org/W1995956587","https://openalex.org/W1998716562","https://openalex.org/W1998774002","https://openalex.org/W1999049822","https://openalex.org/W2002661845","https://openalex.org/W2002806429","https://openalex.org/W2004057696","https://openalex.org/W2005280798","https://openalex.org/W2005795648","https://openalex.org/W2008460460","https://openalex.org/W2008942284","https://openalex.org/W2010655741","https://openalex.org/W2010977236","https://openalex.org/W2011926692","https://openalex.org/W2014961469","https://openalex.org/W2015827415","https://openalex.org/W2017216236","https://openalex.org/W2018524951","https://openalex.org/W2020111779","https://openalex.org/W2021166178","https://openalex.org/W2021277867","https://openalex.org/W2022396491","https://openalex.org/W2023557477","https://openalex.org/W2025925916","https://openalex.org/W2029178926","https://openalex.org/W2029199217","https://openalex.org/W2029959758","https://openalex.org/W2030072508","https://openalex.org/W2030829717","https://openalex.org/W2033908130","https://openalex.org/W2035910879","https://openalex.org/W2037736601","https://openalex.org/W2039604618","https://openalex.org/W2040101471","https://openalex.org/W2040562022","https://openalex.org/W2041364995","https://openalex.org/W2041368597","https://openalex.org/W2042456025","https://openalex.org/W2045557689","https://openalex.org/W2046639404","https://openalex.org/W2046978144","https://openalex.org/W2057355258","https://openalex.org/W2064965107","https://openalex.org/W2068219746","https://openalex.org/W2068863050","https://openalex.org/W2069788601","https://openalex.org/W2071243414","https://openalex.org/W2074161440","https://openalex.org/W2076025228","https://openalex.org/W2077220975","https://openalex.org/W2079044372","https://openalex.org/W2079169365","https://openalex.org/W2079551829","https://openalex.org/W2082457290","https://openalex.org/W2083710155","https://openalex.org/W2084948269","https://openalex.org/W2091160459","https://openalex.org/W2091815063","https://openalex.org/W2092393537","https://openalex.org/W2096835803","https://openalex.org/W2102786755","https://openalex.org/W2103058426","https://openalex.org/W2103633180","https://openalex.org/W2108471741","https://openalex.org/W2113018585","https://openalex.org/W2114775560","https://openalex.org/W2122169732","https://openalex.org/W2122701363","https://openalex.org/W2127075341","https://openalex.org/W2139236978","https://openalex.org/W2140008218","https://openalex.org/W2140312798","https://openalex.org/W2149828751","https://openalex.org/W2156665431","https://openalex.org/W2157568983","https://openalex.org/W2169623960","https://openalex.org/W2312972666","https://openalex.org/W2318328193","https://openalex.org/W2322282312","https://openalex.org/W2327862059","https://openalex.org/W2329784726","https://openalex.org/W2330828932","https://openalex.org/W2334889346","https://openalex.org/W2335647820","https://openalex.org/W2465193095","https://openalex.org/W3183916201","https://openalex.org/W4285719527","https://openalex.org/W6605282992"],"related_works":["https://openalex.org/W4377022168","https://openalex.org/W3127009327","https://openalex.org/W2011901387","https://openalex.org/W3107052846","https://openalex.org/W2561128397","https://openalex.org/W2991326193","https://openalex.org/W2516958976","https://openalex.org/W127357150","https://openalex.org/W134131678","https://openalex.org/W4392984900"],"abstract_inverted_index":{"Asymmetric":[0],"flow":[1],"field-flow":[2,16],"fractionation":[3,174,194],"(AF4)":[4],"is":[5,180,188],"a":[6,20,28,40,43,55,185],"widely":[7],"used":[8,92,201],"and":[9,31,53,60,99,105,111,134,144,160,199,208],"versatile":[10],"technique":[11,165],"in":[12,176,182],"the":[13,91,97,153,158,170,177,191,205,209,220],"family":[14],"of":[15,24,58,90,101,119,155,162,172],"fractionations,":[17],"indicated":[18],"by":[19],"rapidly":[21],"increasing":[22],"number":[23],"publications.":[25],"It":[26],"represents":[27],"gentle":[29],"separation":[30,45,178],"characterization":[32,57,118],"method,":[33],"where":[34],"nonspecific":[35],"interactions":[36],"are":[37],"reduced":[38],"to":[39,51,66,73,219],"minimum,":[41],"allows":[42],"broad":[44],"range":[46],"from":[47],"several":[48],"nano-":[49],"up":[50,215],"micrometers":[52],"enables":[54],"superior":[56],"homo-":[59],"heterogenic":[61],"systems.":[62],"In":[63,94],"particular,":[64],"coupling":[65],"multiangle":[67],"light":[68],"scattering":[69],"provides":[70],"detailed":[71],"access":[72],"sample":[74],"properties.":[75],"Information":[76],"about":[77],"molar":[78],"mass,":[79],"polydispersity,":[80],"size,":[81],"shape/conformation,":[82],"or":[83,123],"density":[84],"can":[85],"be":[86,115,150,167],"obtained":[87,156],"nearly":[88],"independent":[89],"material.":[93],"this":[95,163],"Perspective,":[96],"application":[98],"progress":[100],"AF4":[102],"for":[103,108,146],"(bio)macromolecules":[104],"colloids,":[106],"relevant":[107,141],"\"nano\"":[109],"medical":[110],"pharmaceutical":[112],"issues,":[113],"will":[114,149,166],"presented.":[116],"The":[117,212],"different":[120,173],"nanosized":[121],"drug":[122],"gene":[124],"delivery":[125],"systems,":[126],"e.g.,":[127],"polymers,":[128],"nanoparticles,":[129],"micelles,":[130],"dendrimers,":[131],"liposomes,":[132],"polyplexes,":[133],"virus-like-particles":[135],"(VLP),":[136],"as":[137,139,196,202,204],"well":[138,203],"therapeutic":[140],"proteins,":[142],"antibodies,":[143],"nanoparticles":[145],"diagnostic":[147],"usage":[148],"discussed.":[151],"Thereby,":[152],"variety":[154],"information,":[157],"advantages":[159],"pitfalls":[161],"emerging":[164],"highlighted.":[168],"Additionally,":[169],"influence":[171],"parameters":[175,195],"process":[179],"discussed":[181],"detail.":[183],"Moreover,":[184],"comprehensive":[186],"overview":[187],"given,":[189],"concerning":[190],"investigated":[192],"samples,":[193],"membrane":[197],"types":[198],"buffers":[200],"chosen":[206],"detectors":[207],"corresponding":[210],"references.":[211],"perspective":[213],"ends":[214],"with":[216],"an":[217],"outlook":[218],"future.":[221]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}