{"id":"https://openalex.org/W2319589016","doi":"https://doi.org/10.1364/biomed.2012.btu4a.7","title":"Time Domain Diffuse Fluorescence Tomography Can Increase Small-Animal Imaging Throughput","display_name":"Time Domain Diffuse Fluorescence Tomography Can Increase Small-Animal Imaging Throughput","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2319589016","doi":"https://doi.org/10.1364/biomed.2012.btu4a.7","mag":"2319589016"},"language":"en","primary_location":{"id":"doi:10.1364/biomed.2012.btu4a.7","doi":"https://doi.org/10.1364/biomed.2012.btu4a.7","is_oa":false,"landing_page_url":"https://doi.org/10.1364/biomed.2012.btu4a.7","pdf_url":null,"source":{"id":"https://openalex.org/S7407096837","display_name":"Biomedical Optics and 3-D Imaging","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315679","host_organization_name":"Optica Publishing Group","host_organization_lineage":["https://openalex.org/P4310315679"],"host_organization_lineage_names":["Optica Publishing Group"],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical Optics and 3-D Imaging","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Robert W Holt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert W Holt","raw_affiliation_strings":["Department of Physics and Astronomy, Dartmouth College, NH 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, Dartmouth College, NH 03755, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057677821","display_name":"Kenneth M. Tichauer","orcid":"https://orcid.org/0000-0003-1667-3026","observed_orcids":["https://orcid.org/0000-0003-1667-3026"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kenneth M Tichauer","raw_affiliation_strings":["Thayer School of Engineering, Dartmouth College, NH 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thayer School of Engineering, Dartmouth College, NH 03755, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103157176","display_name":"Qun Song Zhu","orcid":"https://orcid.org/0000-0001-6185-9239","observed_orcids":["https://orcid.org/0000-0001-6185-9239"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Qun Zhu","raw_affiliation_strings":["School of Computer Science, University of Birmingham, Birmingham, B15 2TT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Birmingham, Birmingham, B15 2TT, UK","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022307495","display_name":"Hamid Dehghani","orcid":"https://orcid.org/0000-0003-4117-0412","observed_orcids":["https://orcid.org/0000-0003-4117-0412"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Hamid Dehghani","raw_affiliation_strings":["School of Computer Science, University of Birmingham, Birmingham, B15 2TT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Birmingham, Birmingham, B15 2TT, UK","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091509313","display_name":"Fr\u00e9d\u00e9ric Leblond","orcid":"https://orcid.org/0000-0002-8154-4952","observed_orcids":["https://orcid.org/0000-0002-8154-4952"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frederic Leblond","raw_affiliation_strings":["Thayer School of Engineering, Dartmouth College, NH 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thayer School of Engineering, Dartmouth College, NH 03755, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089497655","display_name":"Brian W. Pogue","orcid":"https://orcid.org/0000-0002-9887-670X","observed_orcids":["https://orcid.org/0000-0002-9887-670X"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Brian W Pogue","raw_affiliation_strings":["Thayer School of Engineering, Dartmouth College, NH 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thayer School of Engineering, Dartmouth College, NH 03755, USA","institution_ids":["https://openalex.org/I107672454"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5022307495","https://openalex.org/A5057677821","https://openalex.org/A5089497655","https://openalex.org/A5091509313","https://openalex.org/A5103157176"],"corresponding_institution_ids":["https://openalex.org/I107672454","https://openalex.org/I79619799"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28526012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":null,"first_page":"BTu4A.7","last_page":"BTu4A.7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/image-reconstruction","display_name":"image reconstruction","score":0.8299999833106995},{"id":"https://openalex.org/keywords/preclinical-imaging","display_name":"small animal imaging","score":0.9350000023841858},{"id":"https://openalex.org/keywords/imaging-throughput","display_name":"imaging throughput","score":0.8669999837875366},{"id":"https://openalex.org/keywords/spatial-resolution","display_name":"spatial resolution","score":0.9810000061988831},{"id":"https://openalex.org/keywords/contrast-enhancement","display_name":"contrast enhancement","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.73148512840271},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.5914324522018433},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.5679050087928772},{"id":"https://openalex.org/C57477423","wikidata":"https://www.wikidata.org/wiki/Q1434196","display_name":"Fluorescence-lifetime imaging microscopy","level":3,"score":0.5504445433616638},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.5347330570220947},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.5114425420761108},{"id":"https://openalex.org/C140779682","wikidata":"https://www.wikidata.org/wiki/Q210868","display_name":"Sampling (signal processing)","level":3,"score":0.5027995109558105},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.47508373856544495},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46869850158691406},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.4461353123188019},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3849688172340393},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3381164073944092},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11998432874679565},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1364/biomed.2012.btu4a.7","doi":"https://doi.org/10.1364/biomed.2012.btu4a.7","is_oa":false,"landing_page_url":"https://doi.org/10.1364/biomed.2012.btu4a.7","pdf_url":null,"source":{"id":"https://openalex.org/S7407096837","display_name":"Biomedical Optics and 3-D Imaging","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315679","host_organization_name":"Optica Publishing Group","host_organization_lineage":["https://openalex.org/P4310315679"],"host_organization_lineage_names":["Optica Publishing Group"],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedical Optics and 3-D Imaging","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.atira.dk:publications/6769aa3d-983a-43b7-abc3-9950dea7b4dc","doi":null,"is_oa":false,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/6769aa3d-983a-43b7-abc3-9950dea7b4dc","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Holt , R W , Tichauer , K M , Zhu , Q , Dehghani , H , Leblond , F & Pogue , B W 2012 , Time domain diffuse fluorescence tomography can increase small-animal imaging throughput . in Biomedical Optics, BIOMED 2012 . Biomedical Optics, BIOMED 2012 , Optical Society of America (OSA) , pp. BTu4A.7 , Biomedical Optics, BIOMED 2012 , Miami, FL , United States , 28/04/12 . https://doi.org/10.1364/biomed.2012.btu4a.7","raw_type":"contributionToPeriodical"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1976616137","https://openalex.org/W1982845691","https://openalex.org/W2047615998","https://openalex.org/W2066192724","https://openalex.org/W2070014357","https://openalex.org/W2070882610","https://openalex.org/W2087768352","https://openalex.org/W2114619432"],"related_works":["https://openalex.org/W2171317940","https://openalex.org/W2134642661","https://openalex.org/W2128953121","https://openalex.org/W2144738836","https://openalex.org/W2037700184","https://openalex.org/W2046344766","https://openalex.org/W2312198241","https://openalex.org/W7099686321","https://openalex.org/W2007995161","https://openalex.org/W2336956531"],"abstract_inverted_index":{"Employing":[0],"multiple":[1],"time-bins":[2],"in":[3],"the":[4],"image":[5],"reconstruction":[6],"of":[7],"a":[8],"time-domain":[9],"fluorescence":[10],"tomography":[11],"dataset":[12],"provides":[13],"improved":[14],"spatial":[15],"resolution":[16],"and":[17,29],"contrast.":[18],"Furthermore,":[19],"these":[20],"gains":[21],"can":[22],"be":[23],"used":[24],"to":[25],"minimize":[26],"tissue":[27],"sampling":[28],"reduce":[30],"imaging":[31],"duration.":[32]},"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2016-06-24T00:00:00"}