{"id":"https://openalex.org/W2318472201","doi":"https://doi.org/10.1016/j.exphem.2014.07.206","title":"DPP4 truncation alters the signaling and functional activity of GM-CSF and LL-3 in normal and leukemic hematopoietic cells","display_name":"DPP4 truncation alters the signaling and functional activity of GM-CSF and LL-3 in normal and leukemic hematopoietic cells","publication_year":2014,"publication_date":"2014-08-01","ids":{"openalex":"https://openalex.org/W2318472201","doi":"https://doi.org/10.1016/j.exphem.2014.07.206","mag":"2318472201"},"language":"en","primary_location":{"id":"doi:10.1016/j.exphem.2014.07.206","doi":"https://doi.org/10.1016/j.exphem.2014.07.206","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.exphem.2014.07.206","pdf_url":null,"source":{"id":"https://openalex.org/S72188638","display_name":"Experimental Hematology","issn_l":"0301-472X","issn":["0301-472X","1873-2399"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Hematology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.exphem.2014.07.206","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083744223","display_name":"Heather A. O\u2019Leary","orcid":"https://orcid.org/0000-0003-1321-1520","observed_orcids":["https://orcid.org/0000-0003-1321-1520","https://orcid.org/0000-0002-6664-8075"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather O'Leary","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031468426","display_name":"Charlie Mantel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charlie Mantel","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002600603","display_name":"Man Ryul Lee","orcid":"https://orcid.org/0000-0002-2351-9679","observed_orcids":["https://orcid.org/0000-0002-2351-9679"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Man Ryul Lee","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001715587","display_name":"Xianyin Lai","orcid":"https://orcid.org/0000-0001-7281-6891","observed_orcids":["https://orcid.org/0000-0001-7281-6891"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xianyin Lai","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034118912","display_name":"Scott H. Cooper","orcid":"https://orcid.org/0000-0001-9091-8269","observed_orcids":["https://orcid.org/0000-0001-9091-8269"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott Cooper","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072748567","display_name":"Giao Hangoc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giao Hangoc","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075765460","display_name":"H. Scott Boswell","orcid":"https://orcid.org/0009-0004-8444-6727","observed_orcids":["https://orcid.org/0009-0004-8444-6727"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Scott Boswell","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038161052","display_name":"Hal E. Broxmeyer","orcid":"https://orcid.org/0000-0001-6575-0476","observed_orcids":["https://orcid.org/0000-0001-6575-0476"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hal Broxmeyer","raw_affiliation_strings":["Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA","institution_ids":["https://openalex.org/I4394709130"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4394709130"],"apc_list":{"value":3250,"currency":"USD","value_usd":3250},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.22219238,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"8","first_page":"S55","last_page":"S55"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.6509000062942505,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.6509000062942505,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.1800999939441681,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.02979999966919422,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dipeptidyl-peptidase-4","display_name":"dipeptidyl peptidase IV","score":0.875},{"id":"https://openalex.org/keywords/truncation","display_name":"truncation","score":0.5040000081062317},{"id":"https://openalex.org/keywords/gm-csf","display_name":"GM-CSF","score":0.9350000023841858},{"id":"https://openalex.org/keywords/hematopoietic-cells","display_name":"hematopoietic cells","score":0.7990000247955322},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.8669999837875366},{"id":"https://openalex.org/keywords/cytokine-signaling","display_name":"cytokine signaling","score":0.777999997138977},{"id":"https://openalex.org/keywords/receptor-activity","display_name":"receptor activity","score":0.30399999022483826}],"concepts":[{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.7488580346107483},{"id":"https://openalex.org/C106195933","wikidata":"https://www.wikidata.org/wiki/Q7847935","display_name":"Truncation (statistics)","level":2,"score":0.7438381910324097},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.47538554668426514},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4165298640727997},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4104350209236145},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37912020087242126},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3309888243675232},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.17011180520057678},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.096443772315979},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.exphem.2014.07.206","doi":"https://doi.org/10.1016/j.exphem.2014.07.206","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.exphem.2014.07.206","pdf_url":null,"source":{"id":"https://openalex.org/S72188638","display_name":"Experimental Hematology","issn_l":"0301-472X","issn":["0301-472X","1873-2399"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Hematology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.exphem.2014.07.206","doi":"https://doi.org/10.1016/j.exphem.2014.07.206","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.exphem.2014.07.206","pdf_url":null,"source":{"id":"https://openalex.org/S72188638","display_name":"Experimental Hematology","issn_l":"0301-472X","issn":["0301-472X","1873-2399"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Hematology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2477644498","https://openalex.org/W2597885346","https://openalex.org/W2048589029","https://openalex.org/W2924663086","https://openalex.org/W769317228","https://openalex.org/W156323551","https://openalex.org/W2027299746","https://openalex.org/W2318865536","https://openalex.org/W2018634697","https://openalex.org/W191729212"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}