{"id":"https://openalex.org/W231740115","doi":null,"title":"Specificities of acylglycerols and phospholipids for interaction with phorbol ester receptor on Friend leukemia cells.","display_name":"Specificities of acylglycerols and phospholipids for interaction with phorbol ester receptor on Friend leukemia cells.","publication_year":1985,"publication_date":"1985-06-01","ids":{"openalex":"https://openalex.org/W231740115","mag":"231740115","pmid":"https://pubmed.ncbi.nlm.nih.gov/3160629"},"language":"en","primary_location":{"id":"pmid:3160629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3160629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese journal of cancer research : Gann","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109914108","display_name":"Kiyoko Tanaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098918","display_name":"Tokyo Metropolitan Institute of Medical Science","ror":"https://ror.org/00vya8493","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210098918"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Tanaka","raw_affiliation_strings":["The Tokyo Metropolitan Institute of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Tokyo Metropolitan Institute of Medical Science","institution_ids":["https://openalex.org/I4210098918"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005261297","display_name":"Tetsuo Ono","orcid":"https://orcid.org/0000-0002-9838-828X","observed_orcids":["https://orcid.org/0000-0002-9838-828X"]},"institutions":[{"id":"https://openalex.org/I4210098918","display_name":"Tokyo Metropolitan Institute of Medical Science","ror":"https://ror.org/00vya8493","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210098918"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Ono","raw_affiliation_strings":["The Tokyo Metropolitan Institute of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Tokyo Metropolitan Institute of Medical Science","institution_ids":["https://openalex.org/I4210098918"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210098918"],"apc_list":null,"apc_paid":null,"fwci":0.3852,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.50317962,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"76","issue":"6","first_page":"502","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.019600000232458115,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.007699999958276749,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phorbol-ester-receptor","display_name":"phorbol ester receptor","score":0.972000002861023},{"id":"https://openalex.org/keywords/protein-kinase-c","display_name":"protein kinase C","score":0.8700000047683716},{"id":"https://openalex.org/keywords/glycerides","display_name":"glycerides","score":0.9210000038146973},{"id":"https://openalex.org/keywords/phospholipids","display_name":"phospholipids","score":0.9909999966621399},{"id":"https://openalex.org/keywords/phorbol-dibutyrate-binding","display_name":"phorbol dibutyrate binding","score":0.878000020980835},{"id":"https://openalex.org/keywords/diolein","display_name":"diolein","score":0.9350000023841858},{"id":"https://openalex.org/keywords/phosphatidylserine","display_name":"phosphatidylserine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/endogenous-lipids","display_name":"endogenous lipids","score":0.828000009059906},{"id":"https://openalex.org/keywords/receptor-activation","display_name":"receptor activation","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C195794163","wikidata":"https://www.wikidata.org/wiki/Q420877","display_name":"Protein kinase C","level":3,"score":0.8821486234664917},{"id":"https://openalex.org/C3017695315","wikidata":"https://www.wikidata.org/wiki/Q37713691","display_name":"Phorbol ester","level":4,"score":0.7754645347595215},{"id":"https://openalex.org/C36020004","wikidata":"https://www.wikidata.org/wiki/Q106951674","display_name":"Diacylglycerol kinase","level":4,"score":0.632294774055481},{"id":"https://openalex.org/C200514077","wikidata":"https://www.wikidata.org/wiki/Q407758","display_name":"Glyceride","level":3,"score":0.6215332746505737},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5821050405502319},{"id":"https://openalex.org/C186518008","wikidata":"https://www.wikidata.org/wiki/Q18030780","display_name":"PRKCQ","level":5,"score":0.569239616394043},{"id":"https://openalex.org/C2780043322","wikidata":"https://www.wikidata.org/wiki/Q2705359","display_name":"Phorbol","level":4,"score":0.5630204081535339},{"id":"https://openalex.org/C2779637612","wikidata":"https://www.wikidata.org/wiki/Q2354337","display_name":"Phosphatidylserine","level":4,"score":0.5587462782859802},{"id":"https://openalex.org/C2776387844","wikidata":"https://www.wikidata.org/wiki/Q161466","display_name":"Diglyceride","level":3,"score":0.49788761138916016},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.47747349739074707},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4217264950275421},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4201143980026245},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.41173139214515686},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3583969175815582},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.22745761275291443},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.17558321356773376},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.08040660619735718},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004915","descriptor_name":"Leukemia, Erythroblastic, Acute","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005622","descriptor_name":"Friend murine leukemia virus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005989","descriptor_name":"Glycerides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007942","descriptor_name":"Leukemia, Experimental","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010718","descriptor_name":"Phosphatidylserines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011493","descriptor_name":"Protein Kinase C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011494","descriptor_name":"Protein Kinases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D011955","descriptor_name":"Receptors, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011971","descriptor_name":"Receptors, Immunologic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029742","descriptor_name":"Caenorhabditis elegans Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:3160629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3160629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese journal of cancer research : Gann","raw_type":"Journal Article"},{"id":"mag:231740115","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3160629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W191339276","https://openalex.org/W1483045044","https://openalex.org/W1524875319","https://openalex.org/W1594758412","https://openalex.org/W1970441944","https://openalex.org/W1974638880","https://openalex.org/W1979900159","https://openalex.org/W1982152509","https://openalex.org/W2001692359","https://openalex.org/W2055871144","https://openalex.org/W2059421144","https://openalex.org/W2110720934","https://openalex.org/W2114399588","https://openalex.org/W2160733363","https://openalex.org/W2161798777","https://openalex.org/W2164776383","https://openalex.org/W2283028157","https://openalex.org/W2315971268","https://openalex.org/W2460643174","https://openalex.org/W2996686235"],"related_works":["https://openalex.org/W2460643174","https://openalex.org/W1974638880","https://openalex.org/W2021433243","https://openalex.org/W2069501076","https://openalex.org/W2011946653","https://openalex.org/W2068160121","https://openalex.org/W2428535246","https://openalex.org/W2471801780","https://openalex.org/W1749394363","https://openalex.org/W2076932997"],"abstract_inverted_index":{"For":[0],"the":[1,5,8,15,31,52,58,76,81,86,92,96,110,113,126],"purpose":[2],"of":[3,7,17,26,33,54,60,65,88,128],"characterizing":[4],"nature":[6],"phorbol":[9,55,114,133],"ester":[10,115,134],"receptor":[11,116],"on":[12,30],"intact":[13,46,118,129],"cells,":[14],"effects":[16],"acylglycerols":[18,66],"and":[19,57,124],"phospholipids,":[20],"which":[21],"are":[22],"known":[23],"as":[24,98],"activators":[25],"protein":[27,72,102,121],"kinase":[28,73,103,122],"C,":[29,123],"binding":[32,53,93],"3H-phorbol":[34],"dibutyrate":[35],"to":[36,70,131],"Friend":[37],"erythroid":[38],"leukemia":[39],"cells":[40,47,119,130],"(FLC)":[41],"were":[42,48],"examined.":[43],"Even":[44],"when":[45],"used,":[49],"diolein":[50],"inhibited":[51],"ester,":[56],"degrees":[59],"inhibition":[61],"by":[62,137],"several":[63],"kinds":[64],"paralleled":[67],"their":[68],"abilities":[69],"activate":[71],"C.":[74,104],"On":[75],"other":[77],"hand,":[78],"phosphatidylserine":[79],"enhanced":[80],"binding.":[82],"Among":[83],"phospholipids":[84],"tested,":[85],"order":[87],"activities":[89],"for":[90,100,109],"increasing":[91],"was":[94],"almost":[95],"same":[97],"that":[99,112,125],"activating":[101],"These":[105],"results":[106],"provide":[107],"support":[108],"hypothesis":[111],"in":[117],"is":[120,135],"ability":[127],"bind":[132],"affected":[136],"endogenous":[138],"lipids.":[139]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}