{"id":"https://openalex.org/W2317200739","doi":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","title":"Microbial Endocrinology in the Pathogenesis of Infectious Disease","display_name":"Microbial Endocrinology in the Pathogenesis of Infectious Disease","publication_year":2016,"publication_date":"2016-03-25","ids":{"openalex":"https://openalex.org/W2317200739","doi":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","mag":"2317200739","pmid":"https://pubmed.ncbi.nlm.nih.gov/27227308"},"language":"en","primary_location":{"id":"doi:10.1128/microbiolspec.vmbf-0021-2015","doi":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","is_oa":true,"landing_page_url":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","pdf_url":null,"source":{"id":"https://openalex.org/S2764766708","display_name":"Microbiology Spectrum","issn_l":"2165-0497","issn":["2165-0497"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Spectrum","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055994217","display_name":"Mark Lyte","orcid":"https://orcid.org/0000-0001-8512-2581","observed_orcids":["https://orcid.org/0000-0001-8512-2581"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark Lyte","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011","institution_ids":["https://openalex.org/I173911158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055994217"],"corresponding_institution_ids":["https://openalex.org/I173911158"],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":{"value":2500,"currency":"USD","value_usd":2500},"fwci":0.5437,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.4692156,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"4","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbial-endocrinology","display_name":"microbial endocrinology","score":1.0},{"id":"https://openalex.org/keywords/infectious-disease-pathogenesis","display_name":"infectious disease pathogenesis","score":0.7960000038146973},{"id":"https://openalex.org/keywords/catecholamines","display_name":"catecholamines","score":0.9079999923706055},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.828000009059906},{"id":"https://openalex.org/keywords/device-related-infection","display_name":"device-related infection","score":0.6690000295639038},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"horizontal gene transfer","score":0.972000002861023},{"id":"https://openalex.org/keywords/microbiota-gut-brain-axis","display_name":"microbiota-gut-brain axis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/host-microbe-interactions","display_name":"host-microbe interactions","score":0.8629999756813049},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.5709999799728394}],"concepts":[{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.7605750560760498},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.5695973634719849},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4977252781391144},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4242158532142639},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41260433197021484},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3530186414718628}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004704","descriptor_name":"Endocrinology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056265","descriptor_name":"Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1128/microbiolspec.vmbf-0021-2015","doi":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","is_oa":true,"landing_page_url":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","pdf_url":null,"source":{"id":"https://openalex.org/S2764766708","display_name":"Microbiology Spectrum","issn_l":"2165-0497","issn":["2165-0497"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Spectrum","raw_type":"journal-article"},{"id":"pmid:27227308","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27227308","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology spectrum","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/microbiolspec.vmbf-0021-2015","doi":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","is_oa":true,"landing_page_url":"https://doi.org/10.1128/microbiolspec.vmbf-0021-2015","pdf_url":null,"source":{"id":"https://openalex.org/S2764766708","display_name":"Microbiology Spectrum","issn_l":"2165-0497","issn":["2165-0497"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Spectrum","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":232,"referenced_works":["https://openalex.org/W1617392","https://openalex.org/W16339808","https://openalex.org/W60293109","https://openalex.org/W60886073","https://openalex.org/W77485583","https://openalex.org/W112984908","https://openalex.org/W140682439","https://openalex.org/W150707268","https://openalex.org/W165837538","https://openalex.org/W193148329","https://openalex.org/W193380391","https://openalex.org/W244974531","https://openalex.org/W371629555","https://openalex.org/W597493125","https://openalex.org/W624480778","https://openalex.org/W639545577","https://openalex.org/W1488704456","https://openalex.org/W1495335773","https://openalex.org/W1495439714","https://openalex.org/W1502574671","https://openalex.org/W1525818874","https://openalex.org/W1533304019","https://openalex.org/W1583928526","https://openalex.org/W1584604065","https://openalex.org/W1592867337","https://openalex.org/W1833708609","https://openalex.org/W1838452461","https://openalex.org/W1864360976","https://openalex.org/W1896196962","https://openalex.org/W1929451968","https://openalex.org/W1936499670","https://openalex.org/W1945856785","https://openalex.org/W1957347513","https://openalex.org/W1964088213","https://openalex.org/W1964431636","https://openalex.org/W1964463157","https://openalex.org/W1966435616","https://openalex.org/W1966452112","https://openalex.org/W1967006425","https://openalex.org/W1967374034","https://openalex.org/W1967610770","https://openalex.org/W1968294128","https://openalex.org/W1969140399","https://openalex.org/W1969569744","https://openalex.org/W1969574194","https://openalex.org/W1969615942","https://openalex.org/W1971328162","https://openalex.org/W1971429882","https://openalex.org/W1972471279","https://openalex.org/W1973466998","https://openalex.org/W1975409716","https://openalex.org/W1975700357","https://openalex.org/W1977649927","https://openalex.org/W1977800285","https://openalex.org/W1978739526","https://openalex.org/W1979362403","https://openalex.org/W1980552031","https://openalex.org/W1980933786","https://openalex.org/W1981367331","https://openalex.org/W1981500982","https://openalex.org/W1983983049","https://openalex.org/W1984213393","https://openalex.org/W1989614913","https://openalex.org/W1989957107","https://openalex.org/W1990301237","https://openalex.org/W1990449037","https://openalex.org/W1990956233","https://openalex.org/W1991095697","https://openalex.org/W1991323950","https://openalex.org/W1993910870","https://openalex.org/W1995137874","https://openalex.org/W1995618975","https://openalex.org/W1997961331","https://openalex.org/W2001772471","https://openalex.org/W2002375686","https://openalex.org/W2004087403","https://openalex.org/W2004736065","https://openalex.org/W2006618624","https://openalex.org/W2010501810","https://openalex.org/W2011223551","https://openalex.org/W2011611283","https://openalex.org/W2012136328","https://openalex.org/W2015606968","https://openalex.org/W2015625145","https://openalex.org/W2015975525","https://openalex.org/W2019046633","https://openalex.org/W2019462193","https://openalex.org/W2022667093","https://openalex.org/W2023166004","https://openalex.org/W2023184347","https://openalex.org/W2023205645","https://openalex.org/W2024965284","https://openalex.org/W2026049675","https://openalex.org/W2026211138","https://openalex.org/W2026503311","https://openalex.org/W2026531121","https://openalex.org/W2028325453","https://openalex.org/W2028812334","https://openalex.org/W2029016740","https://openalex.org/W2029036988","https://openalex.org/W2030196938","https://openalex.org/W2030289131","https://openalex.org/W2030299753","https://openalex.org/W2036031516","https://openalex.org/W2036116757","https://openalex.org/W2036183832","https://openalex.org/W2036567162","https://openalex.org/W2037918377","https://openalex.org/W2039609767","https://openalex.org/W2040312670","https://openalex.org/W2040380018","https://openalex.org/W2041032345","https://openalex.org/W2041215328","https://openalex.org/W2041919227","https://openalex.org/W2042220721","https://openalex.org/W2042499954","https://openalex.org/W2043415987","https://openalex.org/W2045357264","https://openalex.org/W2047301149","https://openalex.org/W2048624573","https://openalex.org/W2052873420","https://openalex.org/W2054867424","https://openalex.org/W2055719947","https://openalex.org/W2057193362","https://openalex.org/W2057607409","https://openalex.org/W2061514792","https://openalex.org/W2064070606","https://openalex.org/W2066176460","https://openalex.org/W2067042083","https://openalex.org/W2068213416","https://openalex.org/W2069792343","https://openalex.org/W2071000043","https://openalex.org/W2073366531","https://openalex.org/W2073859309","https://openalex.org/W2078446000","https://openalex.org/W2079206714","https://openalex.org/W2079221824","https://openalex.org/W2079555223","https://openalex.org/W2080797414","https://openalex.org/W2082061263","https://openalex.org/W2082670663","https://openalex.org/W2084097975","https://openalex.org/W2084829207","https://openalex.org/W2085147597","https://openalex.org/W2086085168","https://openalex.org/W2086605687","https://openalex.org/W2086963814","https://openalex.org/W2088650755","https://openalex.org/W2089212821","https://openalex.org/W2090930564","https://openalex.org/W2091326259","https://openalex.org/W2091568425","https://openalex.org/W2092038168","https://openalex.org/W2094101797","https://openalex.org/W2095049938","https://openalex.org/W2095891205","https://openalex.org/W2096274970","https://openalex.org/W2096858216","https://openalex.org/W2097380604","https://openalex.org/W2097730580","https://openalex.org/W2098565046","https://openalex.org/W2099282138","https://openalex.org/W2099594801","https://openalex.org/W2102228478","https://openalex.org/W2102504192","https://openalex.org/W2104851340","https://openalex.org/W2105080434","https://openalex.org/W2105173502","https://openalex.org/W2105988766","https://openalex.org/W2107223821","https://openalex.org/W2109296179","https://openalex.org/W2111154143","https://openalex.org/W2112026004","https://openalex.org/W2112133067","https://openalex.org/W2112673542","https://openalex.org/W2112741355","https://openalex.org/W2114362943","https://openalex.org/W2119961387","https://openalex.org/W2122984467","https://openalex.org/W2123072936","https://openalex.org/W2125243641","https://openalex.org/W2127924016","https://openalex.org/W2128136710","https://openalex.org/W2128578655","https://openalex.org/W2129636343","https://openalex.org/W2132191600","https://openalex.org/W2132929849","https://openalex.org/W2133285072","https://openalex.org/W2134412511","https://openalex.org/W2135736506","https://openalex.org/W2136200360","https://openalex.org/W2137037811","https://openalex.org/W2137150469","https://openalex.org/W2139838818","https://openalex.org/W2140233939","https://openalex.org/W2142156364","https://openalex.org/W2144440398","https://openalex.org/W2146038827","https://openalex.org/W2146186198","https://openalex.org/W2148777395","https://openalex.org/W2149181253","https://openalex.org/W2151132177","https://openalex.org/W2152213031","https://openalex.org/W2154688936","https://openalex.org/W2155897723","https://openalex.org/W2156288767","https://openalex.org/W2160369387","https://openalex.org/W2163214284","https://openalex.org/W2163811759","https://openalex.org/W2164234830","https://openalex.org/W2164342861","https://openalex.org/W2167756183","https://openalex.org/W2170935520","https://openalex.org/W2171081455","https://openalex.org/W2315332680","https://openalex.org/W2319491519","https://openalex.org/W2401128042","https://openalex.org/W2401990632","https://openalex.org/W2402089172","https://openalex.org/W2404129529","https://openalex.org/W2409142236","https://openalex.org/W2412362566","https://openalex.org/W2414257324","https://openalex.org/W2419079719","https://openalex.org/W2479096683","https://openalex.org/W2503322403","https://openalex.org/W4210961847","https://openalex.org/W4211125082","https://openalex.org/W4231691453","https://openalex.org/W4239024323","https://openalex.org/W4239923967","https://openalex.org/W4299707764"],"related_works":["https://openalex.org/W2552348181","https://openalex.org/W193380391","https://openalex.org/W1779146022","https://openalex.org/W1989957107","https://openalex.org/W4388539702","https://openalex.org/W2197229373","https://openalex.org/W3190101275","https://openalex.org/W7075609285","https://openalex.org/W2304657073","https://openalex.org/W2804200306"],"abstract_inverted_index":{"Microbial":[0],"endocrinology":[1,190],"represents":[2],"the":[3,17,25,33,49,56,67,78,94,102,107,123,131,142,164,175,186,192],"intersection":[4],"of":[5,20,37,48,62,69,80,85,97,109,116,136,178,188,208],"two":[6],"seemingly":[7],"disparate":[8],"fields,":[9],"microbiology":[10],"and":[11,13,158,161,195],"neurobiology,":[12],"is":[14,171],"based":[15],"on":[16],"shared":[18,202],"presence":[19],"neurochemicals":[21,51,117,167],"that":[22,52,93,134,169],"are":[23,53],"exactly":[24],"same":[26,50,124,166],"in":[27,32,77,101,111,141,185,191,211],"host":[28,137,143,157],"as":[29,31,59,127],"well":[30],"microorganism.":[34],"The":[35,83],"ability":[36],"microorganisms":[38,119],"to":[39,66,106,149,163,198],"not":[40],"only":[41],"respond":[42,162],"to,":[43],"but":[44],"also":[45],"produce,":[46],"many":[47],"produced":[54],"by":[55,118,130],"host,":[57,132],"such":[58],"during":[60],"periods":[61],"stress,":[63],"has":[64,74,89],"led":[65],"introduction":[68],"this":[70],"evolutionary-based":[71],"mechanism":[72],"which":[73],"a":[75,206],"role":[76,187,207],"pathogenesis":[79],"infectious":[81,199,212],"disease.":[82,200,213],"consideration":[84],"microbial":[86,179,189],"endocrinology-based":[87],"mechanisms":[88],"demonstrated,":[90],"for":[91,205],"example,":[92],"prevalent":[95],"use":[96],"catecholamine-based":[98],"synthetic":[99],"drugs":[100],"clinical":[103],"setting":[104],"contributes":[105],"formation":[108],"biofilms":[110],"indwelling":[112],"medical":[113],"devices.":[114],"Production":[115],"most":[120],"often":[121],"employs":[122],"biosynthetic":[125],"pathways":[126,203],"those":[128],"utilized":[129],"indicating":[133],"acquisition":[135],"neurochemical-based":[138],"signaling":[139],"system":[140],"may":[144],"have":[145],"been":[146],"acquired":[147],"due":[148],"lateral":[150],"gene":[151],"transfer":[152],"from":[153],"microorganisms.":[154],"That":[155],"both":[156],"microorganism":[159],"produce":[160],"very":[165],"means":[168],"there":[170],"bidirectionality":[172],"contained":[173],"with":[174],"theoretical":[176],"underpinnings":[177],"endocrinology.":[180],"This":[181],"can":[182],"be":[183],"seen":[184],"microbiota-gut-brain":[193],"axis":[194],"its":[196],"relevance":[197],"Such":[201],"argue":[204],"microorganism-neurochemical":[209],"interactions":[210]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
