{"id":"https://openalex.org/W23165408","doi":"https://doi.org/10.2165/00044011-200727060-00002","title":"Economic Burden of Haematological Adverse Effects in Cancer Patients","display_name":"Economic Burden of Haematological Adverse Effects in Cancer Patients","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W23165408","doi":"https://doi.org/10.2165/00044011-200727060-00002","mag":"23165408","pmid":"https://pubmed.ncbi.nlm.nih.gov/17506589"},"language":"en","primary_location":{"id":"doi:10.2165/00044011-200727060-00002","doi":"https://doi.org/10.2165/00044011-200727060-00002","is_oa":false,"landing_page_url":"https://doi.org/10.2165/00044011-200727060-00002","pdf_url":null,"source":{"id":"https://openalex.org/S138241747","display_name":"Clinical Drug Investigation","issn_l":"0114-2402","issn":["0114-2402","1173-2563","1179-1918","2196-4920"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Drug Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035272901","display_name":"Sarah Y. Liou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134090","display_name":"Pharmerit (United States)","ror":"https://ror.org/040d4nb67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210134090"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S Y Liou","raw_affiliation_strings":["Pharmerit North America LLC, Bethesda, Maryland 20814, USA","Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmerit North America LLC, Bethesda, Maryland 20814, USA","institution_ids":["https://openalex.org/I4210134090"]},{"raw_affiliation_string":"Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA","institution_ids":["https://openalex.org/I4210134090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024580938","display_name":"Jennifer Stephens","orcid":"https://orcid.org/0000-0002-5623-7934","observed_orcids":["https://orcid.org/0000-0002-5623-7934"]},"institutions":[{"id":"https://openalex.org/I4210134090","display_name":"Pharmerit (United States)","ror":"https://ror.org/040d4nb67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210134090"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J M Stephens","raw_affiliation_strings":["Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA","institution_ids":["https://openalex.org/I4210134090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112472116","display_name":"Kimbach Tran Carpiuc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134090","display_name":"Pharmerit (United States)","ror":"https://ror.org/040d4nb67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210134090"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K T Carpiuc","raw_affiliation_strings":["Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA","institution_ids":["https://openalex.org/I4210134090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101525416","display_name":"Weiwei Feng","orcid":"https://orcid.org/0000-0002-2923-1713","observed_orcids":["https://orcid.org/0000-0002-2923-1713"]},"institutions":[{"id":"https://openalex.org/I4210117619","display_name":"Novartis (United States)","ror":"https://ror.org/028fhxy95","country_code":"US","type":"company","lineage":["https://openalex.org/I1283582996","https://openalex.org/I4210117619"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W Feng","raw_affiliation_strings":["Novartis Pharmaceuticals, Florham Park, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharmaceuticals, Florham Park, New Jersey, USA","institution_ids":["https://openalex.org/I4210117619"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087184017","display_name":"Marc F Botteman","orcid":"https://orcid.org/0000-0003-2808-7163","observed_orcids":["https://orcid.org/0000-0003-2808-7163"]},"institutions":[{"id":"https://openalex.org/I4210134090","display_name":"Pharmerit (United States)","ror":"https://ror.org/040d4nb67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210134090"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M F Botteman","raw_affiliation_strings":["Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmerit North America LLC, 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland, 20814, USA","institution_ids":["https://openalex.org/I4210134090"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080378534","display_name":"Joel W. Hay","orcid":"https://orcid.org/0000-0002-4467-9997","observed_orcids":["https://orcid.org/0000-0002-4467-9997"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J W Hay","raw_affiliation_strings":["University of Southern California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Southern California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5024580938"],"corresponding_institution_ids":["https://openalex.org/I4210134090"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":9.2225,"has_fulltext":false,"cited_by_count":123,"citation_normalized_percentile":{"value":0.9706955,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"27","issue":"6","first_page":"381","last_page":"396"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12708","display_name":"Economic and Financial Impacts of Cancer","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12708","display_name":"Economic and Financial Impacts of Cancer","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.03269999846816063,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hematological-adverse-events","display_name":"hematologic adverse events","score":0.9449999928474426},{"id":"https://openalex.org/keywords/economic-burden","display_name":"economic burden","score":0.8119999766349792},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.9210000038146973},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.9629999995231628},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.7919999957084656},{"id":"https://openalex.org/keywords/chemotherapy-toxicity","display_name":"chemotherapy toxicity","score":0.8100000023841858},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.7039999961853027},{"id":"https://openalex.org/keywords/health-care-costs","display_name":"health care costs","score":0.7689999938011169},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.9900000095367432},{"id":"https://openalex.org/keywords/solid-tumors","display_name":"solid tumors","score":0.7730000019073486},{"id":"https://openalex.org/keywords/cost-drivers","display_name":"cost drivers","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8811072111129761},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.7791428565979004},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5773294568061829},{"id":"https://openalex.org/C2778850193","wikidata":"https://www.wikidata.org/wiki/Q3775974","display_name":"Febrile neutropenia","level":4,"score":0.5129544138908386},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.46334606409072876},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44574347138404846},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.44398200511932373},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42010697722435},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.30782845616340637},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D009503","descriptor_name":"Neutropenia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D009503","descriptor_name":"Neutropenia","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D013921","descriptor_name":"Thrombocytopenia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D013921","descriptor_name":"Thrombocytopenia","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D017048","descriptor_name":"Health Care Costs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017281","descriptor_name":"Cost of Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2165/00044011-200727060-00002","doi":"https://doi.org/10.2165/00044011-200727060-00002","is_oa":false,"landing_page_url":"https://doi.org/10.2165/00044011-200727060-00002","pdf_url":null,"source":{"id":"https://openalex.org/S138241747","display_name":"Clinical Drug Investigation","issn_l":"0114-2402","issn":["0114-2402","1173-2563","1179-1918","2196-4920"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Drug Investigation","raw_type":"journal-article"},{"id":"pmid:17506589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17506589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical drug investigation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1943333141","https://openalex.org/W1966117338","https://openalex.org/W1966140433","https://openalex.org/W1966799113","https://openalex.org/W1972638620","https://openalex.org/W1976303784","https://openalex.org/W1977760357","https://openalex.org/W1998018269","https://openalex.org/W2002501169","https://openalex.org/W2009114414","https://openalex.org/W2015025035","https://openalex.org/W2017605473","https://openalex.org/W2021955443","https://openalex.org/W2028633964","https://openalex.org/W2036949022","https://openalex.org/W2044335440","https://openalex.org/W2044649990","https://openalex.org/W2062382320","https://openalex.org/W2065495412","https://openalex.org/W2066883049","https://openalex.org/W2074062313","https://openalex.org/W2077781144","https://openalex.org/W2079633011","https://openalex.org/W2080512407","https://openalex.org/W2082382250","https://openalex.org/W2083130570","https://openalex.org/W2083336892","https://openalex.org/W2085608271","https://openalex.org/W2088555126","https://openalex.org/W2089340094","https://openalex.org/W2093205745","https://openalex.org/W2105389614","https://openalex.org/W2106921399","https://openalex.org/W2135714170","https://openalex.org/W2136002054","https://openalex.org/W2140910246","https://openalex.org/W2145521414","https://openalex.org/W2154011558","https://openalex.org/W2157752127","https://openalex.org/W2160338980","https://openalex.org/W2169432501","https://openalex.org/W2169453338","https://openalex.org/W2171588044","https://openalex.org/W2171908639","https://openalex.org/W2177459756","https://openalex.org/W2404277350","https://openalex.org/W2409941955","https://openalex.org/W2412684578","https://openalex.org/W2439296104","https://openalex.org/W3143485855","https://openalex.org/W4238628831"],"related_works":["https://openalex.org/W2555519280","https://openalex.org/W2010507811","https://openalex.org/W2106326841","https://openalex.org/W4309549551","https://openalex.org/W2085608271","https://openalex.org/W2062382320","https://openalex.org/W2560318331","https://openalex.org/W2046115847","https://openalex.org/W3027259910","https://openalex.org/W1994017529"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}