{"id":"https://openalex.org/W2316335754","doi":null,"title":"\"Personalized justice complements personalized medicine and the overlapping practice of translational medicine, which hold s that individual differences are caused primarily by genetic and environmental factors. \"","display_name":"\"Personalized justice complements personalized medicine and the overlapping practice of translational medicine, which hold s that individual differences are caused primarily by genetic and environmental factors. \"","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2316335754","mag":"2316335754"},"language":"en","primary_location":{"id":"mag:2316335754","doi":null,"is_oa":false,"landing_page_url":"http://www.drlucire.com/uploads/4/0/2/1/40210161/from_personalized_medicine_to_personalized_justice.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110599337","display_name":"Steven H. Wong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven Wong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085865063","display_name":"Christopher Happy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christopher Happy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048280625","display_name":"Daniel David Blinka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dan Blinka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007604134","display_name":"Susan B. Gock","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. B. Gock","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026093544","display_name":"Jeffrey M. Jentzen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey M. Jentzen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Joseph M. Donald","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph M. Donald","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013902760","display_name":"Yolande Lucire","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yolande Lucire","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032794196","display_name":"Paul J. Orsulak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul J. Orsulak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054000485","display_name":"Tara L. Sander","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tara L. Sander","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053521723","display_name":"Michael A. Wagner","orcid":"https://orcid.org/0000-0002-0214-2403","observed_orcids":["https://orcid.org/0000-0002-0214-2403"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Wagner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0214-2403","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031618629","display_name":"Jennifer R. Wynn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer Wynn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110260710","display_name":"Kiang-Teck Jerry Yeo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kiang-Teck J. Yeo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.31299407,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":0.6980000138282776},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.6349999904632568},{"id":"https://openalex.org/keywords/translational-medicine","display_name":"translational medicine","score":0.9929999709129333},{"id":"https://openalex.org/keywords/cyp2d6","display_name":"CYP2D6","score":0.8600000143051147},{"id":"https://openalex.org/keywords/ugt1a1","display_name":"UGT1A1","score":0.7639999985694885},{"id":"https://openalex.org/keywords/irinotecan","display_name":"irinotecan","score":0.953000009059906},{"id":"https://openalex.org/keywords/drug-toxicity","display_name":"drug toxicity","score":0.5989999771118164},{"id":"https://openalex.org/keywords/drug-metabolism","display_name":"drug metabolism","score":0.3269999921321869}],"concepts":[{"id":"https://openalex.org/C2776134451","wikidata":"https://www.wikidata.org/wiki/Q422244","display_name":"Fluoxetine","level":4,"score":0.7695737481117249},{"id":"https://openalex.org/C2780259306","wikidata":"https://www.wikidata.org/wiki/Q412197","display_name":"Irinotecan","level":4,"score":0.7461078763008118},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6743462085723877},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.5741100907325745},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.5694682598114014},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.487578809261322},{"id":"https://openalex.org/C33664856","wikidata":"https://www.wikidata.org/wiki/Q3271142","display_name":"CYP2D6","level":4,"score":0.44701117277145386},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4429894685745239},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39082956314086914},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3385487198829651},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2858496904373169},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25366127490997314},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.17000114917755127},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.1320335566997528},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.07271024584770203},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.07033795118331909},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2316335754","doi":null,"is_oa":false,"landing_page_url":"http://www.drlucire.com/uploads/4/0/2/1/40210161/from_personalized_medicine_to_personalized_justice.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W591829775","https://openalex.org/W1967329208","https://openalex.org/W1977280638","https://openalex.org/W1980066896","https://openalex.org/W2006575551","https://openalex.org/W2062866182","https://openalex.org/W2072102095","https://openalex.org/W2084749458","https://openalex.org/W2121888520","https://openalex.org/W2135057136","https://openalex.org/W2138879845","https://openalex.org/W2151936813","https://openalex.org/W2154943301","https://openalex.org/W2163039525"],"related_works":["https://openalex.org/W2077816489","https://openalex.org/W4386944376","https://openalex.org/W2105574359","https://openalex.org/W7154606892","https://openalex.org/W2911654063","https://openalex.org/W4286296417","https://openalex.org/W2194938474","https://openalex.org/W4404845595","https://openalex.org/W2781597501","https://openalex.org/W7204041034"],"abstract_inverted_index":{".":[0],"Over":[1],"a":[2,17,31],"10\u2011month":[3],"period,":[4],"he":[5],"developed":[6],"gastrointestinal":[7],"toxicity,":[8],"incoordination":[9],"and":[10,12,25,28,40],"disorientation,":[11],"sei\u2011zures.":[13],"He":[14],"died":[15],"from":[16,48],"cardiac":[18],"arrest.":[19],"Post\u2011mortem":[20],"toxicology":[21],"showed":[22],"high":[23],"fluoxetine":[24,38,51],"norfluoxetine":[26],"concentrations,":[27],"PGx":[29],"revealed":[30],"poor":[32],"CYP2D6":[33],"metabolizer":[34],"geno\u2011type,":[35],"resulting":[36],"in":[37,50],"accumulation":[39],"toxicity.":[41],"Subsequently,":[42],"the":[43],"boy\u2019s":[44],"parent":[45],"were":[46],"absolved":[47],"involvement":[49],"intoxication.":[52],"Another":[53],"example":[54],"is":[55],"genotyping":[56],"uridine":[57],"5\u00b4\u2011diphosphate\u2011glucuronyltransferase":[58],"1A1":[59],"for":[60],"patients":[61],"medicated":[62],"with":[63],"irinotecan":[64],"to":[65],"avoid":[66],"hematopoietic":[67],"toxicity":[68]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}