{"id":"https://openalex.org/W2315078095","doi":"https://doi.org/10.1055/s-0032-1318333","title":"Total Synthesis of Chaetoquadrins H and I","display_name":"Total Synthesis of Chaetoquadrins H and I","publication_year":2013,"publication_date":"2013-03-06","ids":{"openalex":"https://openalex.org/W2315078095","doi":"https://doi.org/10.1055/s-0032-1318333","mag":"2315078095"},"language":"en","primary_location":{"id":"doi:10.1055/s-0032-1318333","doi":"https://doi.org/10.1055/s-0032-1318333","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0032-1318333","pdf_url":null,"source":{"id":"https://openalex.org/S80698544","display_name":"Synlett","issn_l":"0936-5214","issn":["0936-5214","1437-2096"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synlett","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043992105","display_name":"Margaret Anne Brimble","orcid":"https://orcid.org/0000-0002-7086-4096","observed_orcids":["https://orcid.org/0000-0002-7086-4096"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Margaret Brimble","raw_affiliation_strings":["School of Chemical Sciences, The University of Auckland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Sciences, The University of Auckland","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067617463","display_name":"U Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"U Kim","raw_affiliation_strings":["School of Chemical Sciences, The University of Auckland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Sciences, The University of Auckland","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000959966","display_name":"Andrew F. Dalebrook","orcid":"https://orcid.org/0000-0002-3526-9734","observed_orcids":["https://orcid.org/0000-0002-3526-9734"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Andrew Dalebrook","raw_affiliation_strings":["School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland, New Zealand Fax: +64(9)3737422 Email: m.brimble@auckland.ac.nz","School of Chemical Sciences, The University of Auckland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland, New Zealand Fax: +64(9)3737422 Email: m.brimble@auckland.ac.nz","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"School of Chemical Sciences, The University of Auckland","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090938606","display_name":"Daniel P. Furkert","orcid":"https://orcid.org/0000-0001-6286-9105","observed_orcids":["https://orcid.org/0000-0001-6286-9105"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Daniel Furkert","raw_affiliation_strings":["School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland, New Zealand Fax: +64(9)3737422 Email: m.brimble@auckland.ac.nz","School of Chemical Sciences, The University of Auckland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland, New Zealand Fax: +64(9)3737422 Email: m.brimble@auckland.ac.nz","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"School of Chemical Sciences, The University of Auckland","institution_ids":["https://openalex.org/I154130895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000959966","https://openalex.org/A5043992105","https://openalex.org/A5067617463","https://openalex.org/A5090938606"],"corresponding_institution_ids":["https://openalex.org/I154130895"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.15910116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"24","issue":"06","first_page":"723","last_page":"726"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13023","display_name":"Synthesis of Organic Compounds","score":0.86080002784729,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13023","display_name":"Synthesis of Organic Compounds","score":0.86080002784729,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.0632999986410141,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13221","display_name":"Biological Activity of Diterpenoids and Biflavonoids","score":0.01640000008046627,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-synthesis","display_name":"total synthesis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/aldol-reaction","display_name":"aldol reaction","score":0.8259999752044678},{"id":"https://openalex.org/keywords/acid-catalyzed-cyclization","display_name":"acid-catalyzed cyclization","score":0.890999972820282},{"id":"https://openalex.org/keywords/monoamine-oxidase-inhibition","display_name":"monoamine oxidase inhibition","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9435340166091919},{"id":"https://openalex.org/C61156836","wikidata":"https://www.wikidata.org/wiki/Q494392","display_name":"Aldol reaction","level":3,"score":0.8458350896835327},{"id":"https://openalex.org/C35753019","wikidata":"https://www.wikidata.org/wiki/Q644785","display_name":"Total synthesis","level":2,"score":0.7491146326065063},{"id":"https://openalex.org/C2779326954","wikidata":"https://www.wikidata.org/wiki/Q420156","display_name":"Chromone","level":2,"score":0.7476690411567688},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6057463884353638},{"id":"https://openalex.org/C2779396153","wikidata":"https://www.wikidata.org/wiki/Q901227","display_name":"Natural product","level":2,"score":0.4749241769313812},{"id":"https://openalex.org/C2778577587","wikidata":"https://www.wikidata.org/wiki/Q3665729","display_name":"Chaetomium","level":3,"score":0.4494641423225403},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4199378490447998},{"id":"https://openalex.org/C84083412","wikidata":"https://www.wikidata.org/wiki/Q267374","display_name":"Prins reaction","level":3,"score":0.41158244013786316},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.37522703409194946},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3223378658294678},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22869136929512024},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.19855737686157227},{"id":"https://openalex.org/C2777484150","wikidata":"https://www.wikidata.org/wiki/Q843136","display_name":"Penicillium","level":2,"score":0.05653160810470581},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-0032-1318333","doi":"https://doi.org/10.1055/s-0032-1318333","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0032-1318333","pdf_url":null,"source":{"id":"https://openalex.org/S80698544","display_name":"Synlett","issn_l":"0936-5214","issn":["0936-5214","1437-2096"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synlett","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320801","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2742840086","https://openalex.org/W2314951110","https://openalex.org/W2950648127","https://openalex.org/W2950840839","https://openalex.org/W2137324830","https://openalex.org/W2523714273","https://openalex.org/W2286181275","https://openalex.org/W2165791722","https://openalex.org/W2140411159","https://openalex.org/W3201112309"],"abstract_inverted_index":{"The":[0,55],"first":[1],"total":[2],"syntheses":[3],"of":[4,57],"the":[5,29,58],"chromone-containing":[6],"natural":[7,74],"products":[8],"chaetoquadrins":[9],"H":[10,25],"and":[11,19,33],"I":[12,44],"are":[13],"reported,":[14],"using":[15],"an":[16,20],"aldol":[17],"reaction":[18],"acid-catalyzed":[21],"deprotection/cyclization/elimination":[22],"sequence.":[23],"Chaetoquadrin":[24,43],"was":[26,45],"isolated":[27,47],"from":[28],"ascomycete":[30],"Chaetomium":[31],"quadrangulatum":[32],"exhibits":[34],"potent":[35],"mouse":[36],"liver":[37],"monoamine":[38],"oxidase":[39],"(MAO)":[40],"inhibitory":[41],"activity.":[42],"not":[46],"in":[48],"sufficient":[49],"quantity":[50],"to":[51],"enable":[52],"biological":[53],"evaluation.":[54],"synthesis":[56],"title":[59],"compounds":[60],"provides":[61],"a":[62,67],"useful":[63],"starting":[64],"point":[65],"for":[66],"medicinal":[68],"chemistry":[69],"program":[70],"focused":[71],"on":[72],"chaetoquadrin":[73],"products.":[75]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}