{"id":"https://openalex.org/W231489541","doi":null,"title":"Soluble transferrin receptors and soluble transferrin receptor - ferritin index in a healthy African population of South Africa","display_name":"Soluble transferrin receptors and soluble transferrin receptor - ferritin index in a healthy African population of South Africa","publication_year":2006,"publication_date":"2006-12-01","ids":{"openalex":"https://openalex.org/W231489541","mag":"231489541"},"language":"en","primary_location":{"id":"mag:231489541","doi":null,"is_oa":false,"landing_page_url":"http://digitalknowledge.cput.ac.za/bitstream/11189/7949/1/Soluble%20Transferrin%20receptors%20and%20Soluble%20Transferrin%20Receptor.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764412088","display_name":"Medical technology SA","issn_l":"1011-5528","issn":["1011-5528"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Medical technology SA","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001334352","display_name":"Tandi Edith Matsha","orcid":"https://orcid.org/0000-0001-7291-714X","observed_orcids":["https://orcid.org/0000-0001-7291-714X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tandi E. Matsha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059867984","display_name":"Lucy T. Brink","orcid":"https://orcid.org/0000-0001-6737-8225","observed_orcids":["https://orcid.org/0000-0001-6737-8225"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucy Brink","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6737-8225","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033148039","display_name":"Susan J. van Rensburg","orcid":"https://orcid.org/0000-0002-2437-8978","observed_orcids":["https://orcid.org/0000-0002-2437-8978"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan J. van Rensburg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2437-8978","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5041928208","display_name":"Rajiv Timothy Erasmus","orcid":"https://orcid.org/0000-0001-6831-4215","observed_orcids":["https://orcid.org/0000-0001-6831-4215"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rajiv T. Erasmus","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6831-4215","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.203,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.56202736,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":"2","first_page":"5","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/soluble-transferrin-receptor","display_name":"soluble transferrin receptor","score":1.0},{"id":"https://openalex.org/keywords/iron-deficiency","display_name":"iron deficiency","score":0.7599999904632568},{"id":"https://openalex.org/keywords/iron-status-assessment","display_name":"iron status assessment","score":0.7519999742507935},{"id":"https://openalex.org/keywords/serum-ferritin","display_name":"serum ferritin","score":0.9649999737739563},{"id":"https://openalex.org/keywords/transferrin-saturation","display_name":"transferrin saturation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/iron-stores","display_name":"iron stores","score":0.7440000176429749},{"id":"https://openalex.org/keywords/iron-overload","display_name":"iron overload","score":0.7599999904632568},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.4339999854564667}],"concepts":[{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.8567135334014893},{"id":"https://openalex.org/C2776485076","wikidata":"https://www.wikidata.org/wiki/Q7558947","display_name":"Soluble transferrin receptor","level":5,"score":0.8232102990150452},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.7007366418838501},{"id":"https://openalex.org/C153852466","wikidata":"https://www.wikidata.org/wiki/Q907072","display_name":"Transferrin saturation","level":4,"score":0.6819286942481995},{"id":"https://openalex.org/C32264632","wikidata":"https://www.wikidata.org/wiki/Q1134983","display_name":"Transferrin receptor","level":3,"score":0.6325448751449585},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5695419311523438},{"id":"https://openalex.org/C2777417653","wikidata":"https://www.wikidata.org/wiki/Q1313081","display_name":"Iron deficiency","level":3,"score":0.5676716566085815},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47339928150177},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.457139790058136},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.45704227685928345},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4347774386405945},{"id":"https://openalex.org/C3019184707","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Serum ferritin","level":3,"score":0.40929827094078064},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3239400088787079},{"id":"https://openalex.org/C3019673199","wikidata":"https://www.wikidata.org/wiki/Q6073056","display_name":"Iron status","level":4,"score":0.30221670866012573},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.24883514642715454},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:231489541","doi":null,"is_oa":false,"landing_page_url":"http://digitalknowledge.cput.ac.za/bitstream/11189/7949/1/Soluble%20Transferrin%20receptors%20and%20Soluble%20Transferrin%20Receptor.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764412088","display_name":"Medical technology SA","issn_l":"1011-5528","issn":["1011-5528"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Medical technology SA","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W26591162","https://openalex.org/W55541686","https://openalex.org/W1551586253","https://openalex.org/W1578728271","https://openalex.org/W1579613226","https://openalex.org/W1924847619","https://openalex.org/W1930624773","https://openalex.org/W1931717752","https://openalex.org/W1965214728","https://openalex.org/W1972453020","https://openalex.org/W1996648045","https://openalex.org/W2019757220","https://openalex.org/W2022173105","https://openalex.org/W2031696756","https://openalex.org/W2049645388","https://openalex.org/W2099320317","https://openalex.org/W2102434796","https://openalex.org/W2114015514","https://openalex.org/W2131310817","https://openalex.org/W2146532311","https://openalex.org/W2152054410","https://openalex.org/W2152058159","https://openalex.org/W2168894365","https://openalex.org/W2326945383","https://openalex.org/W4211235902"],"related_works":["https://openalex.org/W2084133634","https://openalex.org/W2413244829","https://openalex.org/W7015573811","https://openalex.org/W2094423327","https://openalex.org/W1874733875","https://openalex.org/W2186422603","https://openalex.org/W2787990307","https://openalex.org/W2044828244","https://openalex.org/W1996390451","https://openalex.org/W2081845103"],"abstract_inverted_index":{"Background:":[0],"South":[1],"Africa":[2],"has":[3],"a":[4],"high":[5],"incidence":[6],"of":[7,35,41,50,71,162,267,273],"iron":[8,36,61,72,119,179,239,268,274],"deficiency":[9,37,120],"and":[10,52,68,86,105,125,143,152,216,225,245],"HIV":[11],"/":[12],"Aids.":[13],"The":[14,160],"soluble":[15,65],"transferrin":[16,66,106,126,144,194],"receptor":[17],"(sTfR)":[18],"is":[19,26,30],"not":[20],"an":[21,81],"acute":[22],"phase":[23],"reactant":[24],"as":[25,97,99,117,178,219],"ferritin,":[27],"hence":[28],"it":[29],"useful":[31],"for":[32],"the":[33,39,48,200,238,271],"diagnosis":[34,272],"in":[38,58,74,172,211,270],"presence":[40],"inflammation":[42],"or":[43],"infection.":[44],"\nMethods:":[45],"To":[46],"explore":[47],"use":[49],"sTfR":[51,53,85,100,133,163,201,209,256,278],"-":[54,92,101,110,147,197,202,257],"log":[55,87,102,203,258],"ferritin":[56,89,103,122,142,184,187,204,243,259],"index":[57,104,205,260],"evaluating":[59],"body":[60],"status,":[62],"we":[63,253],"measured":[64],"receptors":[67],"indirect":[69],"measures":[70],"stores":[73,269],"371":[75],"healthy":[76],"Africans.":[77],"\nResults:":[78],"We":[79],"observed":[80,236],"inverse":[82],"correlation":[83],"between":[84,213,237],"serum":[88,141,183],"(r":[90,108],"=":[91,109],"0.17,":[93],"P":[94,112,156,229],"<":[95,113,123,128,157,230],"0.0001),":[96],"well":[98],"saturation":[107,127,145,195],"0.26,":[111],"0.0001).":[114],"Subjects":[115],"classified":[116,177,218],"having":[118],"(serum":[121,186,242],"30\u00b5g/L":[124],"15%)":[129],"had":[130],"significantly":[131],"higher":[132],"concentrations":[134,161],"when":[135,277],"compared":[136],"to":[137,166],"subjects":[138,173,217],"with":[139,264],"normal":[140,165,246],"15":[146,196],"50%,":[148],"(9.2":[149],"\u00b1":[150,154,169,223,227],"6.9\u00b5g/ml":[151],"5.0":[153],"2.4\u00b5g/ml,":[155],"0.0001)":[158],"respectively.":[159],"were":[164,235],"increased":[167],"(5.5":[168],"3.2":[170],"\u00b5g/ml)":[171],"who":[174],"may":[175],"be":[176,261],"deficient":[180],"based":[181],"on":[182,250],"levels":[185,188],"less":[189],"than":[190],"30":[191],"\u00b5g/L,":[192],"but":[193],"50%).":[198],"However,":[199],"was":[206],"superior":[207],"over":[208],"values":[210],"differentiating":[212],"this":[214],"group":[215,241],"normal,":[220],"respectively,":[221],"4.6":[222],"4.1":[224],"2.6":[226],"1.2,":[228],"0.0001.":[231],"No":[232],"significant":[233],"differences":[234],"overload":[240],"raised)":[244],"subjects.":[247],"\nConclusion:":[248],"Based":[249],"these":[251],"results":[252,280],"suggest":[254],"that":[255],"used":[262],"together":[263],"other":[265],"parameters":[266],"deficiency,":[275],"particularly":[276],"concentration":[279],"are":[281],"equivocal.":[282]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}