{"id":"https://openalex.org/W2314229155","doi":"https://doi.org/10.3181/00379727-30-6893","title":"A Rapid Combined Slide Precipitation and Complement Fixation Test for Syphilis","display_name":"A Rapid Combined Slide Precipitation and Complement Fixation Test for Syphilis","publication_year":1933,"publication_date":"1933-06-01","ids":{"openalex":"https://openalex.org/W2314229155","doi":"https://doi.org/10.3181/00379727-30-6893","mag":"2314229155"},"language":"en","primary_location":{"id":"doi:10.3181/00379727-30-6893","doi":"https://doi.org/10.3181/00379727-30-6893","is_oa":false,"landing_page_url":"https://doi.org/10.3181/00379727-30-6893","pdf_url":null,"source":{"id":"https://openalex.org/S67514239","display_name":"Experimental Biology and Medicine","issn_l":"0071-3384","issn":["0071-3384","1535-3699","1535-3702"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"L. Rosenthal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"L. Rosenthal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.30155979,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"9","first_page":"1278","last_page":"1280"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14275","display_name":"Historical Medical Research and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/syphilis","display_name":"syphilis","score":0.7739999890327454},{"id":"https://openalex.org/keywords/complement-fixation-test","display_name":"complement fixation test","score":0.8679999709129333},{"id":"https://openalex.org/keywords/combined-test","display_name":"combined test","score":0.4309999942779541},{"id":"https://openalex.org/keywords/flocculation","display_name":"flocculation","score":0.8119999766349792},{"id":"https://openalex.org/keywords/wassermann-test","display_name":"Wassermann reaction","score":0.7680000066757202},{"id":"https://openalex.org/keywords/syphilitic-serum","display_name":"syphilitic serum","score":0.8529999852180481},{"id":"https://openalex.org/keywords/antigens","display_name":"antigens","score":0.4560000002384186},{"id":"https://openalex.org/keywords/rapid-diagnostic-tests","display_name":"rapid diagnostic tests","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C152669594","wikidata":"https://www.wikidata.org/wiki/Q904197","display_name":"Complement fixation test","level":4,"score":0.911736011505127},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.6734691858291626},{"id":"https://openalex.org/C112313634","wikidata":"https://www.wikidata.org/wiki/Q7886648","display_name":"Complement (music)","level":5,"score":0.5746610164642334},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5580210089683533},{"id":"https://openalex.org/C146249460","wikidata":"https://www.wikidata.org/wiki/Q2914991","display_name":"Fixation (population genetics)","level":3,"score":0.5309008359909058},{"id":"https://openalex.org/C107054158","wikidata":"https://www.wikidata.org/wiki/Q25257","display_name":"Precipitation","level":2,"score":0.4795607924461365},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39811643958091736},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31394249200820923},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2659156620502472},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.16398319602012634},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16105470061302185},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.1370885968208313},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.05270731449127197},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.0},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C153294291","wikidata":"https://www.wikidata.org/wiki/Q25261","display_name":"Meteorology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3181/00379727-30-6893","doi":"https://doi.org/10.3181/00379727-30-6893","is_oa":false,"landing_page_url":"https://doi.org/10.3181/00379727-30-6893","pdf_url":null,"source":{"id":"https://openalex.org/S67514239","display_name":"Experimental Biology and Medicine","issn_l":"0071-3384","issn":["0071-3384","1535-3699","1535-3702"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Biology and Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.44999998807907104,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"},{"score":0.4300000071525574,"id":"https://metadata.un.org/sdg/13","display_name":"Climate action"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2049570500","https://openalex.org/W2921172695","https://openalex.org/W2012753023","https://openalex.org/W2033023411","https://openalex.org/W2090005533","https://openalex.org/W2993647494","https://openalex.org/W2462236299","https://openalex.org/W2411368235","https://openalex.org/W1977159553","https://openalex.org/W4230819286"],"abstract_inverted_index":{"The":[0,23],"reaction":[1],"between":[2],"syphilitic":[3,44,91,230,256,286],"serum":[4,112,185,231,257,287],"and":[5,60,94,113,158,168,177,186,232,265,288],"antigen":[6,93,187,233],"manifests":[7],"itself":[8],"either":[9],"in":[10,17,42,68,98,136,141,161,170,215,282,291,296,299],"the":[11,36,43,46,56,62,69,77,80,83,87,90,102,134,137,142,146,154,189,209,212,216,227,239,242,247,255,263,269,277,304],"formation":[12,190],"of":[13,19,58,71,79,86,130,156,184,191,203,211,229,249,279,285],"a":[14,27,66,127,150,182,192,283],"precipitate":[15,193],"or":[16,33],"fixation":[18,24,57,129,160,176,210],"an":[20,171,201],"added":[21,179,245],"complement.":[22],"process":[25],"is":[26,49],"prolonged":[28],"one,":[29],"requiring":[30],"one":[31,162],"hour":[32,207],"more,":[34],"while":[35,101],"precipitation":[37,104,143],"occurs":[38],"almost":[39],"immediately.":[40],"Since":[41],"sera":[45],"same":[47,138,147],"principle":[48],"accepted":[50],"to":[51,118,125,173,181,205,237],"be":[52,123,260],"responsible":[53],"for":[54,64,208],"both":[55,72],"complement":[59,95,131,159,175,180,213,240,264,281],"flocculation,":[61],"reason":[63],"such":[65,149],"difference":[67],"course":[70],"reactions":[73],"may":[74],"depend":[75],"on":[76],"concentration":[78,139],"ingredients.":[81],"In":[82,220,271],"various":[84],"modifications":[85],"Wassermann":[88,218],"test":[89],"serum,":[92],"are":[96],"used":[97,295],"diluted":[99],"form,":[100],"newest":[103],"tests":[105],"(Kahn,":[106],"Citochol,":[107],"Kline,":[108],"Rosenthal)":[109],"employ":[110],"undiluted":[111],"concentrated":[114],"antigen.":[115,270],"It":[116],"occurred":[117],"us":[119],"that":[120,226,254,276],"it":[121],"might":[122],"possible":[124],"obtain":[126],"rapid":[128],"by":[132],"using":[133],"ingredients":[135],"as":[140,214],"tests.":[144],"At":[145],"time":[148],"procedure":[151],"would":[152],"permit":[153],"combination":[155],"flocculation":[157],"test.":[163,219],"Keining,":[164],"Kafka,":[165],"Kahn,":[166],"Landau":[167],"McDermott,":[169],"attempt":[172],"combine":[174],"floceulation":[178],"mixture":[183,228,284],"after":[188],"had":[194],"already":[195],"taken":[196],"place.":[197],"They":[198],"then":[199,267],"allowed":[200],"incubation":[202],"1/2":[204],"1":[206],"classical":[217],"our":[221,297],"preliminary":[222],"experiments":[223],"we":[224,274],"learned":[225],"was":[234,244],"frequently":[235],"unable":[236],"fix":[238],"if":[241],"latter":[243],"at":[246],"end":[248],"precipitation.":[250,305],"We,":[251],"therefore,":[252],"concluded":[253],"must":[258],"first":[259],"mixed":[261],"with":[262,303],"only":[266],"receive":[268],"many":[272],"controls":[273],"found":[275],"presence":[278],"this":[280],"antigen,":[289],"even":[290],"amounts":[292],"exceeding":[293],"those":[294],"test,":[298],"no":[300],"way":[301],"interfered":[302]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}