{"id":"https://openalex.org/W231256306","doi":"https://doi.org/10.1182/blood.v75.6.1356.1356","title":"Allogeneic bone marrow transplantation for leukemia with marrow grafts depleted of lymphocytes by counterflow centrifugation","display_name":"Allogeneic bone marrow transplantation for leukemia with marrow grafts depleted of lymphocytes by counterflow centrifugation","publication_year":1990,"publication_date":"1990-03-15","ids":{"openalex":"https://openalex.org/W231256306","doi":"https://doi.org/10.1182/blood.v75.6.1356.1356","mag":"231256306","pmid":"https://pubmed.ncbi.nlm.nih.gov/2310832"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v75.6.1356.1356","doi":"https://doi.org/10.1182/blood.v75.6.1356.1356","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v75.6.1356.1356","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008425039","display_name":"A Schattenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A Schattenberg","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108561023","display_name":"T. de Witte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"T De Witte","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091608460","display_name":"Frank W. M. B. Preijers","orcid":"https://orcid.org/0000-0002-7394-7364","observed_orcids":["https://orcid.org/0000-0002-7394-7364"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"F Preijers","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026185552","display_name":"John M. M. Raemaekers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J Raemaekers","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031364930","display_name":"Petra Muus","orcid":"https://orcid.org/0000-0002-2560-3882","observed_orcids":["https://orcid.org/0000-0002-2560-3882"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P Muus","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066982062","display_name":"Nico van der Lely","orcid":"https://orcid.org/0000-0002-6996-0099","observed_orcids":["https://orcid.org/0000-0002-6996-0099"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"N Van der Lely","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111676667","display_name":"J.B.M. Boezeman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J Boezeman","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110361496","display_name":"J. A. Wessels","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J Wessels","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075117886","display_name":"B Van Dijk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"B Van Dijk","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109955227","display_name":"J. Hoogenhout","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J Hoogenhout","raw_affiliation_strings":["Division of Hematology, University Hospital Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, University Hospital Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I145872427"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":4.8461,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.95404369,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"75","issue":"6","first_page":"1356","last_page":"1363"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allogeneic-bone-marrow-transplantation","display_name":"allogeneic bone marrow transplantation","score":0.996999979019165},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.6209999918937683},{"id":"https://openalex.org/keywords/counterflow-centrifugation","display_name":"counterflow centrifugation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hla-matched-sibling-donor","display_name":"matched sibling donor","score":0.8339999914169312},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.9319999814033508},{"id":"https://openalex.org/keywords/acute-lymphoblastic-leukemia","display_name":"acute lymphoblastic leukemia","score":0.9399999976158142},{"id":"https://openalex.org/keywords/chronic-myeloid-leukemia","display_name":"chronic myeloid leukemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/conditioning-regimen","display_name":"conditioning regimen","score":0.5960000157356262},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.878000020980835},{"id":"https://openalex.org/keywords/immunoprophylaxis","display_name":"immunoprophylaxis","score":0.7509999871253967},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.902999997138977},{"id":"https://openalex.org/keywords/graft-failure","display_name":"graft failure","score":0.6669999957084656},{"id":"https://openalex.org/keywords/cytomegalovirus-pneumonia","display_name":"cytomegalovirus pneumonia","score":0.7459999918937683},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.878000020980835},{"id":"https://openalex.org/keywords/leukemia-free-survival","display_name":"leukemia-free survival","score":0.9929999709129333},{"id":"https://openalex.org/keywords/treatment-related-mortality","display_name":"non-relapse mortality","score":0.3799999952316284},{"id":"https://openalex.org/keywords/donor-lymphocyte-infusion","display_name":"donor lymphocyte infusion","score":0.36500000953674316}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7699096202850342},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.659663200378418},{"id":"https://openalex.org/C2776960273","wikidata":"https://www.wikidata.org/wiki/Q729735","display_name":"Chronic myelogenous leukemia","level":3,"score":0.6440742611885071},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.5938215851783752},{"id":"https://openalex.org/C2778880498","wikidata":"https://www.wikidata.org/wiki/Q1986672","display_name":"Total body irradiation","level":4,"score":0.5889092087745667},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.5386713743209839},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5174601674079895},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.506074845790863},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5037183165550232},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4925015866756439},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.49228397011756897},{"id":"https://openalex.org/C2781107101","wikidata":"https://www.wikidata.org/wiki/Q180664","display_name":"Acute lymphocytic leukemia","level":4,"score":0.4303654730319977},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.3355388045310974},{"id":"https://openalex.org/C2909962599","wikidata":"https://www.wikidata.org/wiki/Q180664","display_name":"Lymphoblastic Leukemia","level":3,"score":0.07190167903900146}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002498","descriptor_name":"Centrifugation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002678","descriptor_name":"Chimera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D008212","descriptor_name":"Lymphocyte Depletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1182/blood.v75.6.1356.1356","doi":"https://doi.org/10.1182/blood.v75.6.1356.1356","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v75.6.1356.1356","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"doi:10.1182/blood.v75.6.1356.bloodjournal7561356","doi":"https://doi.org/10.1182/blood.v75.6.1356.bloodjournal7561356","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v75.6.1356.bloodjournal7561356","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:2310832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2310832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W8882568","https://openalex.org/W61630472","https://openalex.org/W143215620","https://openalex.org/W192601643","https://openalex.org/W198186331","https://openalex.org/W311496579","https://openalex.org/W1530764705","https://openalex.org/W1539005347","https://openalex.org/W1596160021","https://openalex.org/W1979123982","https://openalex.org/W1996729197","https://openalex.org/W2032549221","https://openalex.org/W2038514094","https://openalex.org/W2050642909","https://openalex.org/W2052071946","https://openalex.org/W2053278212","https://openalex.org/W2067131989","https://openalex.org/W2067480394","https://openalex.org/W2067889013","https://openalex.org/W2071249703","https://openalex.org/W2091087368","https://openalex.org/W2093136598","https://openalex.org/W2117983550","https://openalex.org/W2128564651","https://openalex.org/W2144291772","https://openalex.org/W2151588959","https://openalex.org/W2163693633","https://openalex.org/W2167541030","https://openalex.org/W2395825358","https://openalex.org/W2398452341","https://openalex.org/W2399978351","https://openalex.org/W2402481516","https://openalex.org/W2403701385","https://openalex.org/W2404313498","https://openalex.org/W2404788769","https://openalex.org/W2411038114","https://openalex.org/W2415098040","https://openalex.org/W2443063763","https://openalex.org/W2462871550","https://openalex.org/W2466736601","https://openalex.org/W2471417254","https://openalex.org/W2472832889","https://openalex.org/W2606631616","https://openalex.org/W2739067006","https://openalex.org/W4240946448"],"related_works":["https://openalex.org/W2409003487","https://openalex.org/W2037845639","https://openalex.org/W1976286442","https://openalex.org/W230217249","https://openalex.org/W2359759431","https://openalex.org/W2411396646","https://openalex.org/W2411038114","https://openalex.org/W2148449018","https://openalex.org/W1872362089","https://openalex.org/W2432209742"],"abstract_inverted_index":{"Eighty":[0],"consecutive":[1],"patients":[2,110,124,159,243,301],"were":[3,86,290,335],"transplanted":[4,244,302],"with":[5,63,104,292,339],"human":[6],"leukocyte":[7],"antigen":[8],"(HLA)-identical":[9],"sibling":[10],"marrow":[11,36,361],"for":[12,182,197,210,234,245,256,260,269,303,324,363,371],"acute":[13,20,129,343],"myelogenous":[14,29],"leukemia":[15,22,30,325],"(AML,":[16],"N":[17,24,32],"=":[18,25,33],"29),":[19],"lymphoid":[21],"(ALL,":[23],"23),":[26],"or":[27,70,84,106,135,263,347,357],"chronic":[28,153,214,353],"(CML,":[31],"28).":[34],"Donor":[35],"was":[37,49,145,155,170,225,272,308,314],"depleted":[38],"of":[39,46,55,95,121,128,151,161,168,221,280,297,306,312,319,342,374],"lymphocytes":[40],"using":[41],"counterflow":[42,365],"centrifugation.":[43],"Median":[44],"age":[45],"the":[47,89,265,340,372],"recipients":[48,296,318],"31":[50],"years.":[51],"Pretransplant":[52],"conditioning":[53,90],"consisted":[54,94],"cyclophosphamide":[56],"and":[57,201,247,275,283,287,310,328,332],"fractionated":[58],"total":[59],"body":[60],"irradiation":[61],"(TBI)":[62],"a":[64,368],"low":[65],"(4.1":[66],"+/-":[67,73],"0.3":[68],"cGy/min)":[69,75],"high":[71],"(13.1":[72],"1.6":[74],"midline":[76],"average":[77],"dose":[78],"rate.":[79],"In":[80,300,322,359],"43":[81],"patients,":[82],"cytosine-arabinoside":[83],"anthracyclines":[85],"added":[87],"to":[88,137,178,193,206,230,240,252,349],"regimen.":[91],"Immunoprophylaxis":[92],"posttransplant":[93,334],"methotrexate":[96],"(MTX)":[97],"alone,":[98],"cyclosporine":[99],"A":[100],"(CsA)":[101],"in":[102,119,180,184,199,212,242,285,295,317,326],"combination":[103],"MTX,":[105],"CsA":[107],"alone;":[108],"two":[109],"received":[111],"no":[112],"immunoprophylaxis":[113,333],"at":[114,140],"all.":[115],"Graft":[116],"failure":[117],"occurred":[118],"4":[120],"77":[122],"evaluable":[123],"(5%).":[125],"The":[126,147,164,217],"probability":[127,167,220,305,311,341],"graft-versus-host":[130],"disease":[131],"(GVHD)":[132],"greater":[133,345],"than":[134,316,346],"equal":[136,348],"grade":[138,350],"2":[139],"day":[141],"100":[142],"after":[143,195,208,232,254],"transplantation":[144,196,209,233,255,259,362],"15%.":[146],"projected":[148,165,218],"3-year":[149,166,219],"estimate":[150],"extensive":[152,352],"GVHD":[154,344],"12%.":[156],"Only":[157],"three":[158],"died":[160],"cytomegalovirus-interstitial":[162],"pneumonitis.":[163],"relapse":[169,307],"30%":[171],"(95%":[172,190,203,227,237,249],"confidence":[173],"interval":[174],"[CI],":[175],"range":[176],"8%":[177],"53%)":[179],"transplants":[181,289,323],"AML":[183],"first":[185,213],"complete":[186],"remission":[187],"(CR1),":[188],"35%":[189,229],"CI,":[191,204,228,238,250],"1%":[192],"69%)":[194,241],"ALL":[198],"CR1,":[200],"38%":[202],"2%":[205],"74%)":[207],"CML":[211],"phase":[215],"(CP1).":[216],"leukemia-free":[222,270],"survival":[223],"(LFS)":[224],"56%":[226],"77%)":[231],"AML-CR1,":[235,261],"42%":[236],"16%":[239],"ALL-CR1,":[246,262],"49%":[248],"18%":[251],"80%)":[253],"CML-CP1.":[257],"After":[258],"CML-CP1,":[264,304],"median":[266],"follow-up":[267],"time":[268],"survivors":[271],"31+,":[273],"30+,":[274],"21+":[276],"months,":[277],"respectively.":[278],"Probabilities":[279],"relapse,":[281,355],"survival,":[282,356],"LFS":[284,313],"AML-CR1":[286],"ALL-CR1":[288],"comparable":[291],"those":[293],"reported":[294],"untreated":[298,320],"grafts.":[299,321],"higher":[309],"lower":[315],"CR1":[327],"CP1,":[329],"preparative":[330],"regimen":[331],"not":[336],"associated":[337],"significantly":[338],"2,":[351],"GVHD,":[354],"LFS.":[358],"bone":[360],"leukemia,":[364],"centrifugation":[366],"is":[367],"useful":[369],"technique":[370],"prevention":[373],"GVHD.(ABSTRACT":[375],"TRUNCATED":[376],"AT":[377],"400":[378],"WORDS)":[379]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}