{"id":"https://openalex.org/W2312373002","doi":"https://doi.org/10.9790/0853-131037678","title":"The Effect of Zingiber Officinale (Ginger) Extract on Blood Pressure and Heart Rate in Healthy Humans","display_name":"The Effect of Zingiber Officinale (Ginger) Extract on Blood Pressure and Heart Rate in Healthy Humans","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2312373002","doi":"https://doi.org/10.9790/0853-131037678","mag":"2312373002"},"language":"en","primary_location":{"id":"doi:10.9790/0853-131037678","doi":"https://doi.org/10.9790/0853-131037678","is_oa":true,"landing_page_url":"https://doi.org/10.9790/0853-131037678","pdf_url":"https://doi.org/10.9790/0853-131037678","source":{"id":"https://openalex.org/S2764844500","display_name":"IOSR Journal of Dental and Medical Sciences","issn_l":"2279-0853","issn":["2279-0853","2279-0861"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4323237861","host_organization_name":"International organization of Scientific Research (IOSR)","host_organization_lineage":["https://openalex.org/P4323237861"],"host_organization_lineage_names":["International organization of Scientific Research (IOSR)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IOSR Journal of Dental and Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.9790/0853-131037678","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067421634","display_name":"Lekan Sheriff Ojulari","orcid":"https://orcid.org/0000-0002-3405-0116","observed_orcids":["https://orcid.org/0000-0002-3405-0116"]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"L.S Ojulari","raw_affiliation_strings":["- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","institution_ids":["https://openalex.org/I134542131"]},{"raw_affiliation_string":"-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091080658","display_name":"O.T Olatubosun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O.T Olatubosun","raw_affiliation_strings":["- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","institution_ids":["https://openalex.org/I134542131"]},{"raw_affiliation_string":"-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007003952","display_name":"KB Okesina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"K.B Okesina","raw_affiliation_strings":["- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","institution_ids":["https://openalex.org/I134542131"]},{"raw_affiliation_string":"-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012269300","display_name":"Bamidele Victor Owoyele","orcid":"https://orcid.org/0000-0003-3503-9338","observed_orcids":["https://orcid.org/0000-0003-3503-9338"]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"B.V Owoyele","raw_affiliation_strings":["- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"- Department of Physiology , Faculty of Basic Medical Sciences , College of Health Sciences , University of Ilorin , Ilorin , Nigeria","institution_ids":["https://openalex.org/I134542131"]},{"raw_affiliation_string":"-Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I134542131"],"apc_list":null,"apc_paid":null,"fwci":0.7026,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.75480199,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"13","issue":"10","first_page":"76","last_page":"78"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11979","display_name":"Garlic and Onion Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ginger","display_name":"ginger","score":0.9940000176429749},{"id":"https://openalex.org/keywords/ginger-extract","display_name":"ginger extract","score":0.9610000252723694},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.9879999756813049},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.9959999918937683},{"id":"https://openalex.org/keywords/antihypertensive-effect","display_name":"antihypertensive effect","score":0.8109999895095825},{"id":"https://openalex.org/keywords/dose-dependent-effects","display_name":"dose-dependent effects","score":0.871999979019165},{"id":"https://openalex.org/keywords/systolic-blood-pressure","display_name":"systolic blood pressure","score":0.8080000281333923},{"id":"https://openalex.org/keywords/diastolic-blood-pressure","display_name":"diastolic blood pressure","score":0.9419999718666077},{"id":"https://openalex.org/keywords/healthy-humans","display_name":"healthy humans","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C2994357274","wikidata":"https://www.wikidata.org/wiki/Q35625","display_name":"Zingiber officinale","level":2,"score":0.9880698323249817},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9392623901367188},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.7572157382965088},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5631482601165771},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5344231724739075},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.3805316686630249},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11966288089752197},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.03545418381690979}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.9790/0853-131037678","doi":"https://doi.org/10.9790/0853-131037678","is_oa":true,"landing_page_url":"https://doi.org/10.9790/0853-131037678","pdf_url":"https://doi.org/10.9790/0853-131037678","source":{"id":"https://openalex.org/S2764844500","display_name":"IOSR Journal of Dental and Medical Sciences","issn_l":"2279-0853","issn":["2279-0853","2279-0861"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4323237861","host_organization_name":"International organization of Scientific Research (IOSR)","host_organization_lineage":["https://openalex.org/P4323237861"],"host_organization_lineage_names":["International organization of Scientific Research (IOSR)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IOSR Journal of Dental and Medical Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.9790/0853-131037678","doi":"https://doi.org/10.9790/0853-131037678","is_oa":true,"landing_page_url":"https://doi.org/10.9790/0853-131037678","pdf_url":"https://doi.org/10.9790/0853-131037678","source":{"id":"https://openalex.org/S2764844500","display_name":"IOSR Journal of Dental and Medical Sciences","issn_l":"2279-0853","issn":["2279-0853","2279-0861"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4323237861","host_organization_name":"International organization of Scientific Research (IOSR)","host_organization_lineage":["https://openalex.org/P4323237861"],"host_organization_lineage_names":["International organization of Scientific Research (IOSR)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IOSR Journal of Dental and Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7200000286102295,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2312373002.pdf","grobid_xml":"https://content.openalex.org/works/W2312373002.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W1588900700","https://openalex.org/W1982187552","https://openalex.org/W1988150904","https://openalex.org/W2007588642","https://openalex.org/W2010469245","https://openalex.org/W2049624461","https://openalex.org/W2062554727","https://openalex.org/W2169767676","https://openalex.org/W2587419731"],"related_works":["https://openalex.org/W4313430873","https://openalex.org/W3140258430","https://openalex.org/W1498001175","https://openalex.org/W4300594780","https://openalex.org/W1606101409","https://openalex.org/W2083841809","https://openalex.org/W4206616364","https://openalex.org/W2186232704","https://openalex.org/W4301665420","https://openalex.org/W2336196271"],"abstract_inverted_index":{"Zingiber":[0],"officinale":[1],"(ZO)":[2],"has":[3,165],"a":[4,55,68,128,140,166],"long":[5],"history":[6],"of":[7,32,34,48,57,65,82,85,105,111,118,157],"traditional":[8],"use.It":[9],"contains":[10],"several":[11],"constituents":[12],"such":[13],"as":[14],"gingerol,":[15],"gingerdiol,":[16],"gingerdione,":[17],"beta-carotene,":[18],"capsaicin,":[19],"caffeic":[20],"acid":[21],"and":[22,40,51,73,79,98,107,123,139,171],"curumin.The":[23],"present":[24],"study":[25,46],"was":[26],"undertaken":[27],"to":[28],"investigate":[29],"the":[30,37,45,99,124,145],"effect":[31,170,173],"consumption":[33,84,110,156],"ZO":[35,86,137,150,158],"on":[36],"heart":[38,125],"rate":[39],"blood":[41,167],"pressure":[42,168],"(BP).Subjects":[43],"for":[44],"comprised":[47],"22":[49],"males":[50],"38":[52],"females":[53],"making":[54],"total":[56],"60":[58],"subjects.The":[59],"subjects":[60],"were":[61,92],"in":[62,131,143,162],"3":[63],"groups":[64,76],"20":[66],"each;":[67],"Control":[69],"group":[70],"(distilled":[71],"water)":[72],"2":[74],"experimental":[75],"(100mg/kg":[77],"bodyweight":[78,81],"50mg/kg":[80],"oral":[83],"extract).For":[87],"each":[88],"group,":[89],"three":[90],"readings":[91,102,115],"obtained":[93],"per":[94],"subject-one":[95],"before":[96],"administration,":[97],"other":[100],"two":[101],"at":[103,159],"intervals":[104],"2hrs":[106,135],"4hrs":[108,148],"after":[109,136,149],"water":[112],"or":[113],"ZO.The":[114],"taken":[116],"comprise":[117],"systolic":[119,146],"BP,":[120,122,147],"diastolic":[121],"rate.Results":[126],"showed":[127],"significant":[129,141],"(p<0.05)decrease":[130],"all":[132],"measured":[133],"parameters":[134],"administration":[138],"(p<0.05)increase":[142],"only":[144],"administration.It":[151],"can":[152],"be":[153],"concluded":[154],"that":[155],"doses":[160],"employed":[161],"this":[163,172],"study,":[164],"lowering":[169],"is":[174],"dose-dependent.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}
