{"id":"https://openalex.org/W2312371209","doi":"https://doi.org/10.1097/00000421-199806000-00022","title":"A Phase II Trial of Amonafide in Patients With Mixed Mesodermal Tumors of the Uterus","display_name":"A Phase II Trial of Amonafide in Patients With Mixed Mesodermal Tumors of the Uterus","publication_year":1998,"publication_date":"1998-06-01","ids":{"openalex":"https://openalex.org/W2312371209","doi":"https://doi.org/10.1097/00000421-199806000-00022","mag":"2312371209","pmid":"https://pubmed.ncbi.nlm.nih.gov/9626805"},"language":"en","primary_location":{"id":"doi:10.1097/00000421-199806000-00022","doi":"https://doi.org/10.1097/00000421-199806000-00022","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000421-199806000-00022","pdf_url":null,"source":{"id":"https://openalex.org/S130927242","display_name":"American Journal of Clinical Oncology","issn_l":"0277-3732","issn":["0277-3732","1537-453X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020136680","display_name":"Robert F. Asbury","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert Asbury","raw_affiliation_strings":["Department of Medicine in Oncology, University of Rochester School of Medicine, New York, USA","U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine in Oncology, University of Rochester School of Medicine, New York, USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111536542","display_name":"John A. Blessing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]},{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A. Blessing","raw_affiliation_strings":["Department of Medicine in Oncology, University of Rochester School of Medicine (R.A.), Rochester, New York, U.S.A","Division of Gynecologic Oncology, Department of Gynecology, Pennsylvania State University School of Medicine (E.P.), Hershey Medical Center, Hershey, Pennsylvania, U.S.A","Gynecologic Oncology Group, Roswell Park Cancer Institute (J.A.B.), Buffalo, New York, U.S.A","and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Medical Center and Tufts University School of Medicine (H.B.), Boston, Massachusetts, U.S.A","U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine in Oncology, University of Rochester School of Medicine (R.A.), Rochester, New York, U.S.A","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"Division of Gynecologic Oncology, Department of Gynecology, Pennsylvania State University School of Medicine (E.P.), Hershey Medical Center, Hershey, Pennsylvania, U.S.A","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Gynecologic Oncology Group, Roswell Park Cancer Institute (J.A.B.), Buffalo, New York, U.S.A","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Medical Center and Tufts University School of Medicine (H.B.), Boston, Massachusetts, U.S.A","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]},{"raw_affiliation_string":"U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110383005","display_name":"Edward S. Podczaski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]},{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward Podczaski","raw_affiliation_strings":["Department of Medicine in Oncology, University of Rochester School of Medicine (R.A.), Rochester, New York, U.S.A","Division of Gynecologic Oncology, Department of Gynecology, Pennsylvania State University School of Medicine (E.P.), Hershey Medical Center, Hershey, Pennsylvania, U.S.A","Gynecologic Oncology Group, Roswell Park Cancer Institute (J.A.B.), Buffalo, New York, U.S.A","and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Medical Center and Tufts University School of Medicine (H.B.), Boston, Massachusetts, U.S.A","U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine in Oncology, University of Rochester School of Medicine (R.A.), Rochester, New York, U.S.A","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"Division of Gynecologic Oncology, Department of Gynecology, Pennsylvania State University School of Medicine (E.P.), Hershey Medical Center, Hershey, Pennsylvania, U.S.A","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Gynecologic Oncology Group, Roswell Park Cancer Institute (J.A.B.), Buffalo, New York, U.S.A","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Medical Center and Tufts University School of Medicine (H.B.), Boston, Massachusetts, U.S.A","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]},{"raw_affiliation_string":"U.S.A","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072910509","display_name":"Harrison G. Ball","orcid":"https://orcid.org/0000-0002-0766-7401","observed_orcids":["https://orcid.org/0000-0002-0766-7401"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]},{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harrison Ball","raw_affiliation_strings":["Department of Medicine in Oncology, University of Rochester School of Medicine (R.A.), Rochester, New York, U.S.A","Division of Gynecologic Oncology, Department of Gynecology, Pennsylvania State University School of Medicine (E.P.), Hershey Medical Center, Hershey, Pennsylvania, U.S.A","Gynecologic Oncology Group, Roswell Park Cancer Institute (J.A.B.), Buffalo, New York, U.S.A","and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Medical Center and Tufts University School of Medicine (H.B.), Boston, Massachusetts, U.S.A","U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine in Oncology, University of Rochester School of Medicine (R.A.), Rochester, New York, U.S.A","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"Division of Gynecologic Oncology, Department of Gynecology, Pennsylvania State University School of Medicine (E.P.), Hershey Medical Center, Hershey, Pennsylvania, U.S.A","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Gynecologic Oncology Group, Roswell Park Cancer Institute (J.A.B.), Buffalo, New York, U.S.A","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Medical Center and Tufts University School of Medicine (H.B.), Boston, Massachusetts, U.S.A","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]},{"raw_affiliation_string":"U.S.A","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5020136680"],"corresponding_institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.28915451,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"21","issue":"3","first_page":"306","last_page":"307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.8871999979019165,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.8871999979019165,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.06920000165700912,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.02449999935925007,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amonafide","display_name":"amonafide","score":0.9950000047683716},{"id":"https://openalex.org/keywords/uterine-sarcoma","display_name":"uterine sarcoma","score":0.7620000243186951},{"id":"https://openalex.org/keywords/dna-intercalators","display_name":"DNA intercalators","score":0.7639999985694885},{"id":"https://openalex.org/keywords/hematological-toxicity","display_name":"hematologic toxicity","score":0.8519999980926514},{"id":"https://openalex.org/keywords/chemotherapy-toxicity","display_name":"chemotherapy toxicity","score":0.5329999923706055},{"id":"https://openalex.org/keywords/dosing-regimen","display_name":"dosing regimen","score":0.5329999923706055}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9252243638038635},{"id":"https://openalex.org/C2779066055","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Uterus","level":2,"score":0.6903389096260071},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6418378949165344},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.5787595510482788},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4406653046607971},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.42952263355255127},{"id":"https://openalex.org/C31760486","wikidata":"https://www.wikidata.org/wiki/Q7180990","display_name":"Phases of clinical research","level":3,"score":0.41629576683044434},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.40155649185180664},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.373490571975708}],"mesh":[{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007094","descriptor_name":"Imides","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007094","descriptor_name":"Imides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D007546","descriptor_name":"Isoquinolines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007546","descriptor_name":"Isoquinolines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D007970","descriptor_name":"Leukopenia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013921","descriptor_name":"Thrombocytopenia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018199","descriptor_name":"Mixed Tumor, Mesodermal","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D053644","descriptor_name":"Naphthalimides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063065","descriptor_name":"Organophosphonates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00000421-199806000-00022","doi":"https://doi.org/10.1097/00000421-199806000-00022","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000421-199806000-00022","pdf_url":null,"source":{"id":"https://openalex.org/S130927242","display_name":"American Journal of Clinical Oncology","issn_l":"0277-3732","issn":["0277-3732","1537-453X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:9626805","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9626805","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of clinical oncology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G1950154987","display_name":null,"funder_award_id":"CA27469","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4064044179","display_name":"GYNECOLOGIC ONCOLOGY GROUP STATISTICAL AND DATA CENTER","funder_award_id":"U10CA037517","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G537293791","display_name":"Gynecologic Oncology Group","funder_award_id":"U10CA027469","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G70736214","display_name":null,"funder_award_id":"(CA 37517","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2234476155"],"related_works":["https://openalex.org/W1989362082","https://openalex.org/W2321099415","https://openalex.org/W2314915177","https://openalex.org/W2037015855","https://openalex.org/W1974960645","https://openalex.org/W2322342159","https://openalex.org/W2234476155","https://openalex.org/W2066298421","https://openalex.org/W2316574398","https://openalex.org/W1991081057"],"abstract_inverted_index":{"Amonafide":[0],"demonstrated":[1],"a":[2,48,98],"poor":[3,116],"response":[4,100,117],"rate":[5,118],"and":[6,101,119],"substantial":[7,120],"toxicity":[8,77],"in":[9,79],"patients":[10,34,85],"who":[11,35],"had":[12,36,97,103],"measurable,":[13,37],"advanced":[14,38],"mixed":[15,39],"mesodermal":[16,40],"tumors":[17,41],"of":[18,27,42,47,81],"the":[19,43,82],"uterus.":[20],"Amonafide-a":[21],"drug":[22],"that":[23],"acts":[24],"through":[25],"intercalation":[26],"tumor":[28],"DNA-was":[29],"used":[30],"to":[31],"treat":[32],"16":[33],"uterus":[44],"as":[45],"part":[46],"Gynecologic":[49],"Oncology":[50],"Group":[51],"(GOG)":[52],"Phase":[53],"II":[54],"study.":[55],"The":[56],"starting":[57],"dose":[58,111],"was":[59,113],"300":[60],"mg/m2":[61],"intravenously":[62],"over":[63],"1":[64],"hour":[65],"for":[66],"5":[67],"consecutive":[68],"days":[69],"every":[70],"3":[71],"weeks.":[72],"Severe":[73],"or":[74],"life-threatening":[75],"hematologic":[76],"occurred":[78],"50%":[80],"patients.":[83],"Two":[84],"experienced":[86],"vomiting":[87],"requiring":[88],"hospitalization.":[89],"Other":[90],"toxicities":[91],"were":[92],"not":[93],"severe.":[94],"One":[95],"patient":[96],"partial":[99],"one":[102],"stable":[104],"disease,":[105],"each":[106],"lasting":[107],"4":[108],"months.":[109],"This":[110],"schedule":[112],"associated":[114],"with":[115],"toxicity.":[121]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
