{"id":"https://openalex.org/W23074193","doi":null,"title":"To Go or Not to Go? Differential Activation during Response Inhibition in Major Depressive Disorder","display_name":"To Go or Not to Go? Differential Activation during Response Inhibition in Major Depressive Disorder","publication_year":2011,"publication_date":"2011-04-01","ids":{"openalex":"https://openalex.org/W23074193","mag":"23074193"},"language":"en","primary_location":{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/85270","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/85270","pdf_url":"https://hdl.handle.net/2027.42/85270","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/2027.42/85270","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Laura Gabriel","orcid":"https://orcid.org/0000-0003-1967-1712","observed_orcids":["https://orcid.org/0000-0003-1967-1712"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Laura Gabriel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1967-1712","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":1.0},{"id":"https://openalex.org/keywords/response-inhibition","display_name":"response inhibition","score":0.9850000143051147},{"id":"https://openalex.org/keywords/inhibitory-control","display_name":"inhibitory control","score":0.9940000176429749},{"id":"https://openalex.org/keywords/reaction-time-psychology","display_name":"reaction time (psychology)","score":0.7369999885559082},{"id":"https://openalex.org/keywords/set-shifting","display_name":"set-shifting","score":0.7639999985694885},{"id":"https://openalex.org/keywords/psychomotor-retardation","display_name":"psychomotor retardation","score":0.9660000205039978}],"concepts":[{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.7040748596191406},{"id":"https://openalex.org/C67225533","wikidata":"https://www.wikidata.org/wiki/Q7045230","display_name":"Go/no go","level":2,"score":0.6166082620620728},{"id":"https://openalex.org/C2992805700","wikidata":"https://www.wikidata.org/wiki/Q6033829","display_name":"Response inhibition","level":3,"score":0.5741060972213745},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4213276505470276},{"id":"https://openalex.org/C93226319","wikidata":"https://www.wikidata.org/wiki/Q193137","display_name":"Differential (mechanical device)","level":2,"score":0.4169422388076782},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33894073963165283},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.30950796604156494},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.17787933349609375},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09671536087989807},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.06635397672653198},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.060335129499435425},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/85270","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/85270","pdf_url":"https://hdl.handle.net/2027.42/85270","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:23074193","doi":null,"is_oa":false,"landing_page_url":"https://deepblue.lib.umich.edu/handle/2027.42/85270","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/85270","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/85270","pdf_url":"https://hdl.handle.net/2027.42/85270","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W23074193.pdf","grobid_xml":"https://content.openalex.org/works/W23074193.grobid-xml"},"referenced_works_count":114,"referenced_works":["https://openalex.org/W102868126","https://openalex.org/W183149910","https://openalex.org/W856362427","https://openalex.org/W1506088517","https://openalex.org/W1861195098","https://openalex.org/W1967104219","https://openalex.org/W1968918225","https://openalex.org/W1973993335","https://openalex.org/W1982016265","https://openalex.org/W1982378812","https://openalex.org/W1984187963","https://openalex.org/W1984243311","https://openalex.org/W1987382969","https://openalex.org/W1987494247","https://openalex.org/W1991600003","https://openalex.org/W1991756841","https://openalex.org/W1991880588","https://openalex.org/W1997723870","https://openalex.org/W2005108140","https://openalex.org/W2009735175","https://openalex.org/W2010161383","https://openalex.org/W2011334992","https://openalex.org/W2011668290","https://openalex.org/W2013336473","https://openalex.org/W2015905617","https://openalex.org/W2018859682","https://openalex.org/W2021609092","https://openalex.org/W2022192636","https://openalex.org/W2031132359","https://openalex.org/W2031938228","https://openalex.org/W2032851410","https://openalex.org/W2033674186","https://openalex.org/W2035060095","https://openalex.org/W2036970657","https://openalex.org/W2037676457","https://openalex.org/W2038414595","https://openalex.org/W2038472974","https://openalex.org/W2039659140","https://openalex.org/W2042170262","https://openalex.org/W2049197653","https://openalex.org/W2052083332","https://openalex.org/W2053184662","https://openalex.org/W2055030620","https://openalex.org/W2056683160","https://openalex.org/W2056884824","https://openalex.org/W2059275599","https://openalex.org/W2060035881","https://openalex.org/W2060710107","https://openalex.org/W2061195971","https://openalex.org/W2061378977","https://openalex.org/W2062057637","https://openalex.org/W2065297016","https://openalex.org/W2068327720","https://openalex.org/W2068448466","https://openalex.org/W2069860286","https://openalex.org/W2071743179","https://openalex.org/W2072674802","https://openalex.org/W2076246669","https://openalex.org/W2076564052","https://openalex.org/W2079823489","https://openalex.org/W2081122328","https://openalex.org/W2083358167","https://openalex.org/W2089030269","https://openalex.org/W2089732115","https://openalex.org/W2091858219","https://openalex.org/W2092573319","https://openalex.org/W2101262805","https://openalex.org/W2106075391","https://openalex.org/W2106844034","https://openalex.org/W2108337682","https://openalex.org/W2108599940","https://openalex.org/W2110004174","https://openalex.org/W2114613490","https://openalex.org/W2115717171","https://openalex.org/W2116763473","https://openalex.org/W2119261704","https://openalex.org/W2120141787","https://openalex.org/W2120357670","https://openalex.org/W2120781542","https://openalex.org/W2122215233","https://openalex.org/W2123350238","https://openalex.org/W2123722790","https://openalex.org/W2125177185","https://openalex.org/W2125516874","https://openalex.org/W2125917054","https://openalex.org/W2129120672","https://openalex.org/W2132324173","https://openalex.org/W2133747138","https://openalex.org/W2135700734","https://openalex.org/W2139119363","https://openalex.org/W2139843843","https://openalex.org/W2139889254","https://openalex.org/W2140126422","https://openalex.org/W2140887652","https://openalex.org/W2145498806","https://openalex.org/W2147243197","https://openalex.org/W2147831701","https://openalex.org/W2149402043","https://openalex.org/W2152343703","https://openalex.org/W2158658220","https://openalex.org/W2159011576","https://openalex.org/W2160534505","https://openalex.org/W2161064381","https://openalex.org/W2161232689","https://openalex.org/W2162528327","https://openalex.org/W2163144416","https://openalex.org/W2164299175","https://openalex.org/W2165097107","https://openalex.org/W2170435193","https://openalex.org/W2170891230","https://openalex.org/W2171030548","https://openalex.org/W2329691186","https://openalex.org/W2472001703","https://openalex.org/W3119361990"],"related_works":["https://openalex.org/W3176768375","https://openalex.org/W2038472974","https://openalex.org/W7162511462","https://openalex.org/W6907760123","https://openalex.org/W2885280728","https://openalex.org/W1585522554","https://openalex.org/W3034958807","https://openalex.org/W7072330484","https://openalex.org/W2920449313","https://openalex.org/W4313639493"],"abstract_inverted_index":{"Major":[0],"depressive":[1],"disorder":[2],"(MDD)":[3],"is":[4,17,26,211],"often":[5],"the":[6,29,43,70,77,99,151,160,170,198,216],"result":[7],"of":[8,12,72,79,181,192,220],"a":[9,18,93,179,189],"long":[10],"list":[11],"factors,":[13],"one":[14],"such":[15],"factor":[16],"disruption":[19],"in":[20,109,144,169,174,184,205],"frontal":[21,55,167],"brain":[22],"circuitry.More":[23],"specifically,":[24],"MDD":[25,51,82,116,136,161,171,199],"characterized":[27],"by":[28],"inability":[30],"to":[31,68,83,106,124,213],"set":[32],"shift":[33],"and":[34,40,57,103,132,146,154,218],"inhibit":[35],"past":[36],"negative":[37],"memories,":[38],"thoughts,":[39],"feelings.Based":[41],"on":[42,76],"literature,":[44],"it":[45],"was":[46,122],"hypothesized":[47],"that":[48,197],"individuals":[49,80],"with":[50,81,135],"will":[52],"have":[53],"bilateral":[54,166],"hyperactivation":[56],"slower":[58,156],"response":[59,113,157,175],"time":[60,158,176],"during":[61,112],"behavioral":[62],"inhibition,":[63],"as":[64,87,163,165],"both":[65],"are":[66],"thought":[67],"be":[69,178],"manifestation":[71],"greater":[73],"effort":[74],"extended":[75],"part":[78],"maintain":[84],"similar":[85],"accuracy":[86,149],"healthy":[88,118,126],"individuals.The":[89],"current":[90],"study":[91],"used":[92],"computer-based":[94],"inhibitory":[95],"control":[96,119],"(IC)":[97],"paradigm,":[98],"Parametric":[100],"Go/No-go":[101],"(PGNG),":[102],"functional":[104],"MRI":[105],"illuminate":[107],"differences":[108],"neural":[110,222],"activation":[111],"inhibition":[114],"for":[115,159],"versus":[117],"participants.The":[120],"task":[121],"administered":[123],"26":[125,133],"controls":[127],"(Females,":[128,137],"n":[129,138],"=":[130,139],"17)":[131],"subjects":[134],"18).Results":[140],"indicated":[141],"no":[142],"difference":[143],"-Go\u2016":[145],"-No-go\u2016":[147],"target":[148],"between":[150],"two":[152],"groups,":[153],"significantly":[155],"group,":[162],"well":[164],"hypoactivation":[168,195],"group.A":[172],"reduction":[173],"might":[177],"sign":[180],"increased":[182],"interference":[183],"set-shifting,":[185],"and/or":[186],"psychomotor":[187],"slowing,":[188],"common":[190],"symptom":[191],"MDD.Likewise,":[193],"unexpected":[194],"suggests":[196],"group":[200],"has":[201],"an":[202],"overall":[203],"decrement":[204],"functioning":[206],"within":[207],"IC":[208],"circuitry.Further":[209],"research":[210],"needed":[212],"better":[214],"inform":[215],"source":[217],"consequences":[219],"this":[221],"dysfunction.":[223]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}