{"id":"https://openalex.org/W2306548392","doi":null,"title":"A Study on the Effect of Ethidium_Bromide on Virulence Factors ( Protease and Biofilm Formation ) by Klebsiella Pneamoniae Isolated from Different Clinical Sources","display_name":"A Study on the Effect of Ethidium_Bromide on Virulence Factors ( Protease and Biofilm Formation ) by Klebsiella Pneamoniae Isolated from Different Clinical Sources","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2306548392","mag":"2306548392"},"language":"en","primary_location":{"id":"pmh:oai:ojs.localhost:article/29250","doi":null,"is_oa":true,"landing_page_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","pdf_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","source":{"id":"https://openalex.org/S4306401197","display_name":"Journals & Books Hosting (International Knowledge Sharing Platform)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Historical Research Letter; Vol 30 (2016); 1-6","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043614951","display_name":"Nehad A. Taher","orcid":"https://orcid.org/0000-0003-1725-1634","observed_orcids":["https://orcid.org/0000-0003-1725-1634"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nehad A. Taher","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1725-1634","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027115713","display_name":"Batool.A.A. Baqir","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Batool.A.A. Baqir","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5020296131","display_name":"Fatima Rammadan Abdul","orcid":"https://orcid.org/0000-0001-7590-4221","observed_orcids":["https://orcid.org/0000-0001-7590-4221"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatima Rammadan Abdul","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7590-4221","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13849","display_name":"Enterobacteriaceae and Cronobacter Research","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethidium-bromide","display_name":"ethidium bromide","score":0.9610000252723694},{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":1.0},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.9330000281333923},{"id":"https://openalex.org/keywords/proteolytic-activity","display_name":"proteolytic activity","score":0.9639999866485596},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/congo-red-agar","display_name":"Congo red agar","score":0.6669999957084656},{"id":"https://openalex.org/keywords/clinical-isolates","display_name":"clinical isolates","score":0.7639999985694885},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.527999997138977},{"id":"https://openalex.org/keywords/plasmid-dna","display_name":"plasmid DNA","score":0.6840000152587891},{"id":"https://openalex.org/keywords/chromosomal-dna","display_name":"chromosomal DNA","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C2776907736","wikidata":"https://www.wikidata.org/wiki/Q408634","display_name":"Ethidium bromide","level":3,"score":0.8754653334617615},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.8059535026550293},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7973581552505493},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.6361992359161377},{"id":"https://openalex.org/C2778660310","wikidata":"https://www.wikidata.org/wiki/Q177998","display_name":"Agar","level":3,"score":0.6341586112976074},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.6071739792823792},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.5982381701469421},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5882177948951721},{"id":"https://openalex.org/C2779116282","wikidata":"https://www.wikidata.org/wiki/Q131854","display_name":"Klebsiella","level":4,"score":0.47581416368484497},{"id":"https://openalex.org/C62643968","wikidata":"https://www.wikidata.org/wiki/Q574816","display_name":"Agar plate","level":3,"score":0.4742262065410614},{"id":"https://openalex.org/C2779155187","wikidata":"https://www.wikidata.org/wiki/Q114391","display_name":"Congo red","level":3,"score":0.45883482694625854},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.44391515851020813},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26994240283966064},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.22534170746803284},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.22005242109298706},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09498047828674316},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09379264712333679},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.053866297006607056},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C150394285","wikidata":"https://www.wikidata.org/wiki/Q180254","display_name":"Adsorption","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ojs.localhost:article/29250","doi":null,"is_oa":true,"landing_page_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","pdf_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","source":{"id":"https://openalex.org/S4306401197","display_name":"Journals & Books Hosting (International Knowledge Sharing Platform)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Historical Research Letter; Vol 30 (2016); 1-6","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2306548392","doi":null,"is_oa":false,"landing_page_url":"https://www.iiste.org/Journals/index.php/HRL/article/download/29250/30039","pdf_url":null,"source":{"id":"https://openalex.org/S2764863075","display_name":"Historical research letter","issn_l":"2224-3178","issn":["2224-3178"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Historical research letter","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ojs.localhost:article/29250","doi":null,"is_oa":true,"landing_page_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","pdf_url":"http://iiste.org/Journals/index.php/HRL/article/view/29250","source":{"id":"https://openalex.org/S4306401197","display_name":"Journals & Books Hosting (International Knowledge Sharing Platform)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Historical Research Letter; Vol 30 (2016); 1-6","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2306548392.pdf","grobid_xml":"https://content.openalex.org/works/W2306548392.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W1928804885","https://openalex.org/W2009889907","https://openalex.org/W2087464221","https://openalex.org/W2097176108","https://openalex.org/W2106351298","https://openalex.org/W2118615977"],"related_works":["https://openalex.org/W4411615485","https://openalex.org/W7217070907","https://openalex.org/W2358966089","https://openalex.org/W7167935146","https://openalex.org/W2989725635","https://openalex.org/W3081524778","https://openalex.org/W3137426487","https://openalex.org/W7126234103","https://openalex.org/W7061537694","https://openalex.org/W4322100257"],"abstract_inverted_index":{"About":[0],"145":[1],"isolate":[2,76],"of":[3,46,57,77,88,130,137,157,182,190,196,236],"Klebsiell":[4],"a":[5,84],"species":[6],"were":[7,20,33,40,97,172],"isolated":[8],"from":[9,16,54],"different":[10],"clinical":[11],"sources":[12],"for6":[13],"month":[14],"ago":[15],"(1-9-2014":[17],")to(1-2-2015).these":[18],"isolates":[19,96,109,156,189,207,229],"identified":[21,34],"morphologically":[22],"and":[23,25,162,169,205,212],"biochemically":[24],"Api":[26],"20":[27],"kit,thus":[28],"there":[29],"was":[30,125],"only":[31,221],"22isolates":[32],"asKlebsiella":[35],"pneumoniae":[36,192,203],"(15.1%)":[37],"Protease":[38,251],"activity":[39,87,112,161],"tested":[41,98],"by":[42,66,113],"measuring":[43],"the":[44,74,103,108,128,134,154,159,186,194,209,217,227],"diameter":[45],"cleared":[47],"around":[48],"wells":[49],"containing":[50],"bacterial":[51],"cells":[52],"harvested":[53],"18":[55],"h":[56],"incubation":[58],"at37c":[59],"on":[60,99,117,127,133,185],"skim":[61],"milk":[62],"agar":[63,101],"medium":[64,119],"or":[65],"(wells":[67],"method).The":[68],"results":[69,104,195],"showed":[70,83,105,208],"that":[71,106],"k4":[72,204],"is":[73],"higher":[75],"protease":[78,86,160],"production(18mm":[79],"in":[80,90,216],"diameter)while":[81],"k2":[82],"lowest":[85],"(12mm":[89],"diameter).Biofilm":[91],"Formation":[92],"for":[93],"22":[94,155,187],"Klebsiella":[95,228,249],"congo-red":[100,118],"mediumand":[102],"all":[107],"have":[110,149],"(100%)":[111],"forming":[114],"dark":[115],"colonies":[116],"In":[120],"our":[121],"study,":[122],"first":[123],"ttempt":[124],"made":[126],"effect":[129,151],"ethidium":[131,183],"bromide":[132,184],"virulence":[135],"factors":[136],"pathogenic":[138],"bacteria":[139],"(Klebsiella":[140],"pneumoniae)at":[141],"concentrations":[142,166,175,235],"(10":[143,176,237],"-1":[144],"to":[145,178,239],"10":[146,179,240],"-6":[147],")that":[148],"an":[150],"at":[152,174,234],"which":[153],"(K.p)loss":[158],"biofilm":[163],"formationat":[164],"these":[165],"while":[167,220],"little":[168],"normal":[170,218],"activities":[171],"observed":[173],"-7":[177],"-10":[180],")":[181],"studied":[188],"K.":[191],".Also,":[193],"Agarose":[197],"\u2013gel":[198],"electrophoresisof":[199],"both":[200],"(normal":[201],"case)Klebsiella":[202],"cured":[206],"presence":[210],"ofchromosomal":[211],"plasmid":[213],"DNA":[214,223],"bands":[215,224],"case":[219],"chromosomal":[222],"occure":[225],"with":[226,231],"treated":[230],"Ethidium":[232,246],"\u2013Bromide":[233,247],"-2":[238],"-4":[241],").":[242],"Key":[243],"w":[244],"ords:":[245],"\u2013":[248,250],"\u2013Biofilm":[252],".":[253]},"counts_by_year":[],"updated_date":"2026-08-31T07:19:18.363097","created_date":"2016-06-24T00:00:00"}