{"id":"https://openalex.org/W23062500","doi":null,"title":"[Cortical and trabecular bone lesions in insulin-dependent diabetes mellitus].","display_name":"[Cortical and trabecular bone lesions in insulin-dependent diabetes mellitus].","publication_year":1991,"publication_date":"1991-12-01","ids":{"openalex":"https://openalex.org/W23062500","mag":"23062500","pmid":"https://pubmed.ncbi.nlm.nih.gov/1792368"},"language":"es","primary_location":{"id":"pmid:1792368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1792368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista clinica espanola","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007621561","display_name":"D\u00edaz Curiel M","orcid":"https://orcid.org/0000-0002-7762-9398","observed_orcids":["https://orcid.org/0000-0002-7762-9398"]},"institutions":[{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M D\u00edaz Curiel","raw_affiliation_strings":["Servicio de Medicina Interna y Endocrinolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Universidad Aut\u00f3noma, Madrid"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Medicina Interna y Endocrinolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Universidad Aut\u00f3noma, Madrid","institution_ids":["https://openalex.org/I63634437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058658843","display_name":"N Palacios","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Palacios","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041946874","display_name":"Aurelio Rapado","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Rapado","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113563183","display_name":"C. de la Piedra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C de la Piedra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"J L Herrera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J L Herrera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6382,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.68321328,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"189","issue":"9","first_page":"408","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/bone-mineral-content","display_name":"bone mineral content","score":0.8830000162124634},{"id":"https://openalex.org/keywords/cortical-bone","display_name":"cortical bone","score":0.9629999995231628},{"id":"https://openalex.org/keywords/trabecular-bone","display_name":"trabecular bone","score":1.0},{"id":"https://openalex.org/keywords/osteopenia","display_name":"osteopenia","score":0.9850000143051147},{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.8270000219345093},{"id":"https://openalex.org/keywords/mineral-and-bone-metabolism","display_name":"bone mineral metabolism","score":0.7160000205039978},{"id":"https://openalex.org/keywords/bone-loss","display_name":"bone loss","score":0.39800000190734863},{"id":"https://openalex.org/keywords/disease-duration","display_name":"disease duration","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9444023370742798},{"id":"https://openalex.org/C2777083390","wikidata":"https://www.wikidata.org/wiki/Q1367706","display_name":"Osteopenia","level":4,"score":0.7992265224456787},{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.6982235312461853},{"id":"https://openalex.org/C2781451080","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cortical bone","level":2,"score":0.6860108375549316},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6623439788818359},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6221997737884521},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5846102237701416},{"id":"https://openalex.org/C2776343214","wikidata":"https://www.wikidata.org/wiki/Q3512024","display_name":"Trabecular bone score","level":5,"score":0.47201651334762573},{"id":"https://openalex.org/C2776169692","wikidata":"https://www.wikidata.org/wiki/Q4941552","display_name":"Bone disease","level":3,"score":0.4203781485557556},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4105764925479889},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.3917117714881897},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2948891520500183},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.18884438276290894},{"id":"https://openalex.org/C2777425516","wikidata":"https://www.wikidata.org/wiki/Q17083560","display_name":"Quantitative computed tomography","level":4,"score":0.12144434452056885},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001851","descriptor_name":"Bone Diseases, Metabolic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015502","descriptor_name":"Absorptiometry, Photon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015675","descriptor_name":"Osteocalcin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1792368","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1792368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista clinica espanola","raw_type":"Comparative Study"},{"id":"mag:23062500","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1792368","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2410552673","https://openalex.org/W2153502260","https://openalex.org/W2422057714","https://openalex.org/W2147802933","https://openalex.org/W223573694","https://openalex.org/W2108001469","https://openalex.org/W1967940250","https://openalex.org/W2414510400","https://openalex.org/W2325956390","https://openalex.org/W1790825835"],"abstract_inverted_index":{"To":[0],"determinate":[1],"which":[2],"type":[3],"of":[4,26,49,74,79,95,116,124,132],"bone":[5,13,126],"is":[6,118],"damaged":[7],"in":[8,17,23,41,76,85,105],"IDDM,":[9],"we":[10],"assessed":[11],"the":[12,42,46,62,72,89,92,108,122,130],"mineral":[14,43],"content":[15],"(BMC)":[16],"both":[18,77],"cortical":[19],"and":[20,54],"trabecular":[21],"bones,":[22],"a":[24],"group":[25,91],"48":[27],"IDDM":[28],"patients":[29,63,90],"without":[30],"hepatic":[31],"or":[32,35],"kidney":[33],"diseases,":[34],"any":[36],"other":[37],"pathology":[38],"with":[39,67,107,121,129],"implications":[40],"metabolism.":[44],"For":[45],"evaluation":[47],"techniques":[48],"single":[50],"photon":[51,56],"absorptiometry":[52,57],"(SPA)":[53],"double":[55],"(DPA)":[58],"were":[59],"used.":[60],"All":[61],"controlled":[64],"their":[65],"disease":[66,133],"insulin.":[68],"The":[69,114],"results":[70],"showed":[71],"presence":[73],"osteopenia":[75],"types":[78],"bone.":[80],"It":[81],"was":[82,99],"more":[83],"evident":[84],"male":[86],"group.":[87],"In":[88],"mean":[93],"value":[94],"serum":[96],"osteocalcin":[97],"(BGP)":[98],"significantly":[100],"decreased":[101],"(2.34":[102],"+/-":[103],"1.05)":[104],"comparison":[106],"controls":[109],"(p":[110],"less":[111],"than":[112],"0.001).":[113],"deficient":[115],"BMC":[117],"neither":[119],"related":[120],"parameters":[123],"new":[125],"formation":[127],"nor":[128],"time":[131],"evolution.":[134]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}