{"id":"https://openalex.org/W2305801176","doi":null,"title":"nutritional Factors in autism: an Overview of nutritional Factors in the etiology and Management of autism","display_name":"nutritional Factors in autism: an Overview of nutritional Factors in the etiology and Management of autism","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2305801176","mag":"2305801176"},"language":"en","primary_location":{"id":"mag:2305801176","doi":null,"is_oa":false,"landing_page_url":"https://todayspractitioner.com/wp-content/uploads/2013/11/Autism-nutrition-IMCJ_11_1Santhanam.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034058603","display_name":"Balasubramanian Santhanam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Balasubramanian Santhanam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5018612028","display_name":"Barry S. Kendler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barry S. Kendler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1381,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.47502212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.8320000171661377,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.8320000171661377,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13393","display_name":"Child Nutrition and Feeding Issues","score":0.16459999978542328,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":0.9390000104904175},{"id":"https://openalex.org/keywords/dietary-factors","display_name":"dietary factors","score":0.7080000042915344},{"id":"https://openalex.org/keywords/etiology-of-autism","display_name":"autism etiology","score":0.8629999756813049},{"id":"https://openalex.org/keywords/dietary-intervention","display_name":"dietary intervention","score":0.7570000290870667},{"id":"https://openalex.org/keywords/gluten-free-diet","display_name":"gluten-free diet","score":0.9639999866485596},{"id":"https://openalex.org/keywords/casein-free-diet","display_name":"casein-free diet","score":0.9990000128746033},{"id":"https://openalex.org/keywords/food-sensitivity","display_name":"food sensitivity","score":0.7820000052452087},{"id":"https://openalex.org/keywords/dysbiosis","display_name":"dysbiosis","score":0.7940000295639038},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.9319999814033508},{"id":"https://openalex.org/keywords/yeast-overgrowth","display_name":"yeast overgrowth","score":0.6819999814033508},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.847000002861023},{"id":"https://openalex.org/keywords/zinc","display_name":"zinc","score":0.9340000152587891},{"id":"https://openalex.org/keywords/carnosine","display_name":"carnosine","score":0.9929999709129333},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.7850000262260437},{"id":"https://openalex.org/keywords/heavy-metal-toxicity","display_name":"heavy metal toxicity","score":0.9169999957084656},{"id":"https://openalex.org/keywords/nutritional-deficiency","display_name":"nutritional deficiency","score":0.8389999866485596},{"id":"https://openalex.org/keywords/gastrointestinal-diseases","display_name":"gastrointestinal diseases","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.7960977554321289},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.6093103289604187},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5549337863922119},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.50678950548172},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4649594724178314},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4100591540336609},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3100130558013916},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25181013345718384}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2305801176","doi":null,"is_oa":false,"landing_page_url":"https://todayspractitioner.com/wp-content/uploads/2013/11/Autism-nutrition-IMCJ_11_1Santhanam.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W141317774","https://openalex.org/W1965277322","https://openalex.org/W1968628990","https://openalex.org/W1975331319","https://openalex.org/W1978222253","https://openalex.org/W1998069784","https://openalex.org/W2000619876","https://openalex.org/W2002410414","https://openalex.org/W2006101031","https://openalex.org/W2020523926","https://openalex.org/W2036439332","https://openalex.org/W2046462311","https://openalex.org/W2051678629","https://openalex.org/W2053695875","https://openalex.org/W2056354384","https://openalex.org/W2056600842","https://openalex.org/W2068440119","https://openalex.org/W2074469042","https://openalex.org/W2083633216","https://openalex.org/W2087791351","https://openalex.org/W2099876163","https://openalex.org/W2100569624","https://openalex.org/W2104908022","https://openalex.org/W2111110903","https://openalex.org/W2112109116","https://openalex.org/W2114876457","https://openalex.org/W2120400073","https://openalex.org/W2120471983","https://openalex.org/W2125380260","https://openalex.org/W2125524684","https://openalex.org/W2134269151","https://openalex.org/W2134895990","https://openalex.org/W2150032379","https://openalex.org/W2151154977","https://openalex.org/W2151214454","https://openalex.org/W2159604534","https://openalex.org/W2163722994","https://openalex.org/W2164926709","https://openalex.org/W2169220559","https://openalex.org/W2171189029","https://openalex.org/W2416445521"],"related_works":["https://openalex.org/W1518649492","https://openalex.org/W2130515103","https://openalex.org/W2124081273","https://openalex.org/W2019181016","https://openalex.org/W4297461086","https://openalex.org/W7217781348","https://openalex.org/W7120588807","https://openalex.org/W3035626409","https://openalex.org/W7057195975","https://openalex.org/W2109087506"],"abstract_inverted_index":{"Autism":[0,179],"is":[1,42,146,189],"thought":[2],"to":[3,38,123,132,204],"have":[4,62,109,113],"a":[5,43,135,169,195,205],"multifactorial":[6,127],"etiology":[7],"that":[8,115,144,214,232],"includes":[9],"hereditary":[10],"and":[11,32,40,54,74,77,84,183,220,223,231],"environmental":[12,215],"triggers":[13],"accompanied":[14],"by":[15],"gastrointestinal":[16],"disorders,":[17,50],"such":[18],"as":[19,46,149,151],"chronic":[20],"duodenitis,":[21],"gastritis,":[22],"reflux":[23],"esophagitis,":[24],"intestinal":[25,30],"lymphoid":[26],"dysplasia,":[27],"dysbiosis,":[28],"excessive":[29],"permeability,":[31],"yeast":[33],"overgrowth.":[34],"Food":[35],"sensitivity,":[36],"especially":[37],"gluten":[39,73],"casein,":[41],"prominent":[44],"finding,":[45],"are":[47,186],"autoimmunity,":[48],"metabolic":[49],"heavy":[51],"metal":[52],"toxicity,":[53],"nutritional":[55,234],"deficiencies":[56],"or":[57,237],"excesses.":[58],"Accordingly,":[59],"medical":[60],"practitioners":[61],"used":[63],"dietary":[64],"interventions":[65,122,235],"with":[66,154],"varying":[67],"efficacy":[68],"in":[69,134,193,200,209],"autism":[70,116,145],"treatment,":[71],"including":[72],"casein\u2013free":[75],"diets":[76],"use":[78],"of":[79,88,93,100,106,157],"omega-3":[80],"fatty":[81],"acids,":[82],"zinc,":[83],"carnosine.":[85],"With":[86],"most":[87],"these":[89,107],"interventions,":[90],"anecdotal":[91],"reports":[92],"favorable":[94],"responses":[95],"usually":[96],"exceed":[97],"the":[98,125,173,218,228],"number":[99,167],"scientifically":[101],"controlled":[102],"studies,":[103],"but":[104],"several":[105],"studies":[108],"suggested":[110],"efficacy.":[111],"Researchers":[112,212],"concluded":[114],"therapy":[117],"may":[118],"require":[119],"concurrent,":[120],"multiple-agent":[121],"counter":[124],"disease\u2019s":[126,229],"etiology,":[128],"which":[129],"they":[130],"believe":[131,213],"result":[133],"neurologically":[136],"toxic":[137],"body":[138],"burden.":[139],"Bertrand":[140],"et":[141],"al":[142],"estimate":[143],"now":[147],"twice":[148],"prevalent":[150],"Down":[152],"syndrome,":[153],"an":[155],"occurrence":[156,230],"at":[158],"least":[159],"40":[160],"cases":[161],"per":[162],"10":[163],"000":[164],"children.1":[165],"That":[166],"represents":[168],"10-fold":[170],"increase":[171],"over":[172],"last":[174],"2":[175],"decades,":[176],"even":[177],"when":[178],"Spectrum":[180],"Disorder":[181],"(ASD)":[182],"Asperger\u2019s":[184],"syndrome":[185],"excluded.":[187],"Heredity":[188],"one":[190],"causative":[191],"factor":[192],"autism;":[194],"90%":[196],"concordance":[197,207],"rate":[198,208],"occurs":[199],"identical":[201],"twins":[202],"compared":[203],"30%":[206],"fraternal":[210],"twins.2":[211],"factors":[216],"during":[217,224],"fetal":[219],"neonatal":[221],"periods":[222],"early":[225],"childhood":[226],"trigger":[227],"appropriate":[233],"prevent":[236],"possibly":[238],"treat":[239],"it":[240],"effectively.":[241],"abstract":[242]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}