{"id":"https://openalex.org/W2305683228","doi":"https://doi.org/10.3174/ajnr.a4740","title":"A Diffusion Tensor Imaging Study on White Matter Abnormalities in Patients with Type 2 Diabetes Using Tract-Based Spatial Statistics","display_name":"A Diffusion Tensor Imaging Study on White Matter Abnormalities in Patients with Type 2 Diabetes Using Tract-Based Spatial Statistics","publication_year":2016,"publication_date":"2016-03-17","ids":{"openalex":"https://openalex.org/W2305683228","doi":"https://doi.org/10.3174/ajnr.a4740","mag":"2305683228","pmid":"https://pubmed.ncbi.nlm.nih.gov/26988810"},"language":"en","primary_location":{"id":"doi:10.3174/ajnr.a4740","doi":"https://doi.org/10.3174/ajnr.a4740","is_oa":true,"landing_page_url":"https://doi.org/10.3174/ajnr.a4740","pdf_url":"http://www.ajnr.org/content/ajnr/37/8/1462.full.pdf","source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Neuroradiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.ajnr.org/content/ajnr/37/8/1462.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013848104","display_name":"Ying Xiong","orcid":"https://orcid.org/0000-0002-6270-5220","observed_orcids":["https://orcid.org/0000-0002-6270-5220"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Xiong","raw_affiliation_strings":["From the Departments of Radiology (Y.X., W.Z.) Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","aFrom the Departments of Radiology (Y.X., W.Z.)","dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Radiology (Y.X., W.Z.) Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"aFrom the Departments of Radiology (Y.X., W.Z.)","institution_ids":[]},{"raw_affiliation_string":"dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027686173","display_name":"Yi Sui","orcid":"https://orcid.org/0000-0002-8177-1661","observed_orcids":["https://orcid.org/0000-0002-8177-1661"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Sui","raw_affiliation_strings":["Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.) Bioengineering (Y.S., X.J.Z.)","dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","fBioengineering (Y.S., X.J.Z.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.) Bioengineering (Y.S., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"fBioengineering (Y.S., X.J.Z.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100623382","display_name":"Zhipeng Xu","orcid":"https://orcid.org/0000-0001-7957-547X","observed_orcids":["https://orcid.org/0000-0001-7957-547X"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Z. Xu","raw_affiliation_strings":["Department of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","cDepartment of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"cDepartment of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012283744","display_name":"Qi Zhang","orcid":"https://orcid.org/0000-0002-4743-029X","observed_orcids":["https://orcid.org/0000-0002-4743-029X","https://orcid.org/0000-0002-4746-3542"]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Q. Zhang","raw_affiliation_strings":["Neurology (Q.Z.), Tongji Hospital","bNeurology (Q.Z.), Tongji Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology (Q.Z.), Tongji Hospital","institution_ids":["https://openalex.org/I4210160344"]},{"raw_affiliation_string":"bNeurology (Q.Z.), Tongji Hospital","institution_ids":["https://openalex.org/I4210160344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056117361","display_name":"Muge Karaman","orcid":"https://orcid.org/0000-0002-7080-7307","observed_orcids":["https://orcid.org/0000-0002-7080-7307"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. M. Karaman","raw_affiliation_strings":["Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016231205","display_name":"Kejia Cai","orcid":"https://orcid.org/0000-0003-1511-4273","observed_orcids":["https://orcid.org/0000-0003-1511-4273"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Cai","raw_affiliation_strings":["Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.) Departments of Radiology (K.C., T.M.A., X.J.Z.)","dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","eDepartments of Radiology (K.C., T.M.A., X.J.Z.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.) Departments of Radiology (K.C., T.M.A., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"eDepartments of Radiology (K.C., T.M.A., X.J.Z.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. M. Anderson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. M. Anderson","raw_affiliation_strings":["Departments of Radiology (K.C., T.M.A., X.J.Z.)","eDepartments of Radiology (K.C., T.M.A., X.J.Z.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Radiology (K.C., T.M.A., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"eDepartments of Radiology (K.C., T.M.A., X.J.Z.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019580757","display_name":"Weifeng Zhu","orcid":"https://orcid.org/0000-0003-0679-0691","observed_orcids":["https://orcid.org/0000-0003-0679-0691"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Zhu","raw_affiliation_strings":["From the Departments of Radiology (Y.X., W.Z.)","aFrom the Departments of Radiology (Y.X., W.Z.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Radiology (Y.X., W.Z.)","institution_ids":[]},{"raw_affiliation_string":"aFrom the Departments of Radiology (Y.X., W.Z.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077820917","display_name":"J. Wang","orcid":"https://orcid.org/0000-0001-7635-4209","observed_orcids":["https://orcid.org/0000-0001-7635-4209"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"J. Wang","raw_affiliation_strings":["Department of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China xjzhou@uic.edu wangjz@mail.hust.edu.cn","cDepartment of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China xjzhou@uic.edu wangjz@mail.hust.edu.cn","institution_ids":["https://openalex.org/I47720641"]},{"raw_affiliation_string":"cDepartment of Pathophysiology (Z.X., J.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030482841","display_name":"Xiaohong Joe Zhou","orcid":"https://orcid.org/0000-0003-0793-4925","observed_orcids":["https://orcid.org/0000-0003-0793-4925"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I4210125096","display_name":"University of Illinois Hospital & Health Sciences System","ror":"https://ror.org/03jhe7195","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210125096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"X. J. Zhou","raw_affiliation_strings":["Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.) Departments of Radiology (K.C., T.M.A., X.J.Z.) Bioengineering (Y.S., X.J.Z.) Neurosurgery (X.J.Z.), University of Illinois Hospital and Health Sciences System, Chicago, Illinois. xjzhou@uic.edu wangjz@mail.hust.edu.cn","dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","eDepartments of Radiology (K.C., T.M.A., X.J.Z.)","fBioengineering (Y.S., X.J.Z.)","gNeurosurgery (X.J.Z.), University of Illinois Hospital and Health Sciences System, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.) Departments of Radiology (K.C., T.M.A., X.J.Z.) Bioengineering (Y.S., X.J.Z.) Neurosurgery (X.J.Z.), University of Illinois Hospital and Health Sciences System, Chicago, Illinois. xjzhou@uic.edu wangjz@mail.hust.edu.cn","institution_ids":["https://openalex.org/I39422238","https://openalex.org/I4210125096"]},{"raw_affiliation_string":"dCenter for Magnetic Resonance Research (Y.X., Y.S., M.M.K., K.C., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"eDepartments of Radiology (K.C., T.M.A., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"fBioengineering (Y.S., X.J.Z.)","institution_ids":[]},{"raw_affiliation_string":"gNeurosurgery (X.J.Z.), University of Illinois Hospital and Health Sciences System, Chicago, Illinois","institution_ids":["https://openalex.org/I4210125096"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.9905,"has_fulltext":true,"cited_by_count":68,"citation_normalized_percentile":{"value":0.95041539,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"37","issue":"8","first_page":"1462","last_page":"1469"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9929999709129333},{"id":"https://openalex.org/keywords/white-matter-abnormalities","display_name":"white matter abnormalities","score":0.8930000066757202},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.9890000224113464},{"id":"https://openalex.org/keywords/diffusion-tensor-imaging","display_name":"diffusion tensor imaging","score":0.8230000138282776},{"id":"https://openalex.org/keywords/fractional-anisotropy","display_name":"fractional anisotropy","score":0.984000027179718},{"id":"https://openalex.org/keywords/mean-diffusivity","display_name":"mean diffusivity","score":0.9890000224113464},{"id":"https://openalex.org/keywords/radial-diffusivity","display_name":"radial diffusivity","score":0.9900000095367432},{"id":"https://openalex.org/keywords/axial-diffusivity","display_name":"axial diffusivity","score":0.8970000147819519},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.5379999876022339},{"id":"https://openalex.org/keywords/cingulum","display_name":"cingulum","score":0.9089999794960022},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.6349999904632568},{"id":"https://openalex.org/keywords/dementia-risk","display_name":"dementia risk","score":0.6570000052452087},{"id":"https://openalex.org/keywords/white-matter-microstructure","display_name":"white matter microstructure","score":0.6549999713897705},{"id":"https://openalex.org/keywords/tract-based-spatial-statistics","display_name":"tract-based spatial statistics","score":0.6330000162124634},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"receiver operating characteristic","score":0.6399999856948853},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C89916169","wikidata":"https://www.wikidata.org/wiki/Q17014600","display_name":"Fractional anisotropy","level":4,"score":0.8151592016220093},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7846600413322449},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6712231040000916},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.6269986629486084},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.5975186824798584},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5560975670814514},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5254320502281189},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.4284919202327728},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4238317608833313},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.35855987668037415},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.20282626152038574},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.15753942728042603},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.11197489500045776},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.10886475443840027},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.07370713353157043}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3174/ajnr.a4740","doi":"https://doi.org/10.3174/ajnr.a4740","is_oa":true,"landing_page_url":"https://doi.org/10.3174/ajnr.a4740","pdf_url":"http://www.ajnr.org/content/ajnr/37/8/1462.full.pdf","source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Neuroradiology","raw_type":"journal-article"},{"id":"pmid:26988810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26988810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR. American journal of neuroradiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4983498","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4983498","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"AJNR Am J Neuroradiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3174/ajnr.a4740","doi":"https://doi.org/10.3174/ajnr.a4740","is_oa":true,"landing_page_url":"https://doi.org/10.3174/ajnr.a4740","pdf_url":"http://www.ajnr.org/content/ajnr/37/8/1462.full.pdf","source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Neuroradiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/4","score":0.5799999833106995,"display_name":"Quality education"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G161652857","display_name":null,"funder_award_id":"81471230","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3020629045","display_name":"\u57fa\u4e8e\u201c\u94c1\u86cb\u767d-\u9ad3\u9798-\u8f74\u7a81\u201d\u673a\u5236\u7684\u591a\u6a21\u6001MRI\u5bf9\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u65e9\u671f\u9884\u6d4b\u7814\u7a76","funder_award_id":"81171308","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6330590049","display_name":"A High-End 3 Tesla Human MRI Scanner Dedicated to Research","funder_award_id":"1s10rr028898-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G756972680","display_name":null,"funder_award_id":"S10 RR028898","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2305683228.pdf","grobid_xml":"https://content.openalex.org/works/W2305683228.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1974366107","https://openalex.org/W1974428095","https://openalex.org/W1986760411","https://openalex.org/W1992837786","https://openalex.org/W1994844104","https://openalex.org/W2000450302","https://openalex.org/W2009036027","https://openalex.org/W2019724009","https://openalex.org/W2034278153","https://openalex.org/W2035351162","https://openalex.org/W2047152236","https://openalex.org/W2087918092","https://openalex.org/W2092014599","https://openalex.org/W2092829693","https://openalex.org/W2102528806","https://openalex.org/W2112256576","https://openalex.org/W2116962025","https://openalex.org/W2118463227","https://openalex.org/W2121483283","https://openalex.org/W2125988557","https://openalex.org/W2141866284","https://openalex.org/W2142185053","https://openalex.org/W2147945386","https://openalex.org/W2148828979","https://openalex.org/W2150106022","https://openalex.org/W2150667092","https://openalex.org/W2153022901","https://openalex.org/W2153444597","https://openalex.org/W2153594538","https://openalex.org/W2168261002","https://openalex.org/W2520432709","https://openalex.org/W2977883299","https://openalex.org/W4210953420","https://openalex.org/W4241151929"],"related_works":["https://openalex.org/W3031573373","https://openalex.org/W2017539237","https://openalex.org/W2607776059","https://openalex.org/W2063361377","https://openalex.org/W2802561361","https://openalex.org/W4205593364","https://openalex.org/W2415162139","https://openalex.org/W2487470953","https://openalex.org/W3118966479","https://openalex.org/W2080220338"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,80],"PURPOSE:":[2],"Patients":[3],"with":[4,45,68,73,84,93,103,111,166,202,210,232,255,258,275,339,349,372,377,397,417,425],"type":[5,46,69,85,167,340,373,398,426],"2":[6,47,70,86,164,168,341,374,399,427],"diabetes":[7,48,71,87,169,200,208,230,256,273,342,375,400,428],"mellitus":[8,49,72,201,209,231,257,274,376,429],"have":[9,24],"considerably":[10,215],"higher":[11],"risk":[12],"of":[13,158,183,420],"developing":[14],"cognitive":[15,41,77,95,204,234,260,301,332,381,393,421],"impairment":[16,96,205,235,333],"and":[17,34,38,74,100,114,143,181,190,206,223,236,278,293,378,409],"dementia.":[18],"WM":[19,36,185,217,411],"changes":[20,227,242,270,412],"in":[21,43,65,135,252,297,395,423],"these":[22],"patients":[23,44,67,83,254,338,371,396,424],"been":[25],"reported.":[26],"Our":[27],"aim":[28],"was":[29,129,347,357],"to":[30,60,131,300,360],"demonstrate":[31],"that":[32,179,314,413],"gradual":[33,408],"continuous":[35,410],"change":[37],"the":[39,133,148,156,163,184,199,207,229,237,253,272,279,309,322,352,355],"associated":[40,416],"decline":[42,394,422],"can":[50,57,365,414,432],"be":[51,58,415,433],"captured":[52],"by":[53,124,246,436],"DTI":[54,122,159,363,404],"parameters,":[55],"which":[56],"used":[59,130],"complement":[61],"neuropsychological":[62,439],"test":[63],"scores":[64],"identifying":[66],"without":[75,379],"mild":[76,94,203,233,259,331,380],"impairment.":[78,261],"MATERIALS":[79],"METHODS:":[81],"Forty-two":[82],"mellitus,":[88],"divided":[89],"into":[90],"a":[91,101,318,367],"group":[92,102],"(n":[97,106,118],"=":[98,107,119],"20)":[99],"normal":[104,211,276,335],"cognition":[105,212,277,336],"22),":[108],"were":[109,243],"enrolled":[110],"age-,":[112],"sex-,":[113],"education-matched":[115],"healthy":[116,238,280],"controls":[117],"26).":[120],"3T":[121],"followed":[123],"Tract-Based":[125,174],"Spatial":[126,175],"Statistics":[127,176],"analysis":[128,154,177,307],"investigate":[132],"differences":[134],"fractional":[136,188,220,290,315,345],"anisotropy,":[137],"mean":[138,192,224,294,326,350],"diffusivity,":[139,351],"axial":[140],"diffusivity":[141,145,193,225,250,263,295,327],"(\u03bb1),":[142],"radial":[144,249],"(\u03bb23)":[146],"among":[147,337],"groups.":[149,240,282],"A":[150],"receiver":[151,304],"operating":[152,305],"characteristic":[153,306],"assessed":[155],"performance":[157],"parameters":[160,364,405],"for":[161,329,391],"separating":[162,330],"groups":[165],"mellitus.":[170,343,401],"RESULTS:":[171],"The":[172,303],"whole-brain":[173],"revealed":[178],"7.3%":[180],"24.9%":[182],"exhibited":[186,265],"decreased":[187],"anisotropy":[189,221,291,316,346],"increased":[191],"(P":[194],"<":[195],".05),":[196],"respectively,":[197],"between":[198,228,271,370],"groups,":[213],"while":[214],"larger":[216,319],"regions":[218,298],"showed":[219,288,313],"(36.6%)":[222],"(58.8%)":[226],"control":[239,281],"These":[241],"caused":[244],"primarily":[245],"an":[247,388],"elevated":[248],"observed":[251],"Radial":[262],"also":[264],"subtle":[266],"but":[267],"statistically":[268],"significant":[269],"Analyses":[283],"on":[284,308],"individual":[285],"fiber":[286],"tracts":[287],"pronounced":[289],"reduction":[292],"elevation":[296],"related":[299],"functions.":[302],"right":[310],"cingulum":[311],"(hippocampus)":[312],"produced":[317],"area":[320,353],"under":[321,354],"curve":[323,356],"(0.832)":[324],"than":[325],"(0.753)":[328],"from":[334],"When":[344],"combined":[348],"further":[358],"improved":[359],"0.857.":[361],"CONCLUSIONS:":[362],"show":[366],"substantial":[368],"difference":[369],"impairment,":[382],"suggesting":[383],"their":[384],"potential":[385],"use":[386],"as":[387],"imaging":[389],"marker":[390],"detecting":[392],"More":[402],"important,":[403],"may":[406],"capture":[407],"early":[418],"stages":[419],"before":[430],"they":[431],"diagnosed":[434],"clinically":[435],"using":[437],"conventional":[438],"tests.":[440]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}