{"id":"https://openalex.org/W2302890945","doi":"https://doi.org/10.6004/jnccn.2014.0085","title":"False-Positive Elevations of Carcinoembryonic Antigen in Patients With a History of Resected Colorectal Cancer","display_name":"False-Positive Elevations of Carcinoembryonic Antigen in Patients With a History of Resected Colorectal Cancer","publication_year":2014,"publication_date":"2014-06-01","ids":{"openalex":"https://openalex.org/W2302890945","doi":"https://doi.org/10.6004/jnccn.2014.0085","mag":"2302890945","pmid":"https://pubmed.ncbi.nlm.nih.gov/24925201","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8409326"},"language":"en","primary_location":{"id":"doi:10.6004/jnccn.2014.0085","doi":"https://doi.org/10.6004/jnccn.2014.0085","is_oa":false,"landing_page_url":"https://doi.org/10.6004/jnccn.2014.0085","pdf_url":null,"source":{"id":"https://openalex.org/S935620192","display_name":"Journal of the National Comprehensive Cancer Network","issn_l":"1540-1405","issn":["1540-1405","1540-1413"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4324004213","host_organization_name":"National Comprehensive Cancer","host_organization_lineage":["https://openalex.org/P4324004213"],"host_organization_lineage_names":["National Comprehensive Cancer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Comprehensive Cancer Network","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8409326","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062853695","display_name":"Anya M. Litvak","orcid":"https://orcid.org/0000-0002-8413-0106","observed_orcids":["https://orcid.org/0000-0002-8413-0106"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anya Litvak","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031539570","display_name":"Andrea Cercek","orcid":"https://orcid.org/0000-0002-5054-8192","observed_orcids":["https://orcid.org/0000-0002-5054-8192"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Cercek","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062202820","display_name":"Neil Howard Segal","orcid":"https://orcid.org/0000-0002-3047-2303","observed_orcids":["https://orcid.org/0000-0002-3047-2303"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil Segal","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032598163","display_name":"Diane L. Reidy\u2010Lagunes","orcid":"https://orcid.org/0000-0003-2688-4556","observed_orcids":["https://orcid.org/0000-0003-2688-4556"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane Reidy-Lagunes","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074087271","display_name":"Zsofia Kinga Stadler","orcid":"https://orcid.org/0000-0002-6985-2864","observed_orcids":["https://orcid.org/0000-0002-6985-2864"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zsofia K. Stadler","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038339239","display_name":"Rona D. Yaeger","orcid":"https://orcid.org/0000-0002-7233-5454","observed_orcids":["https://orcid.org/0000-0002-7233-5454"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rona D. Yaeger","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069644669","display_name":"Nancy E. Kemeny","orcid":"https://orcid.org/0000-0002-0929-9542","observed_orcids":["https://orcid.org/0000-0002-0929-9542"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy E. Kemeny","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013157364","display_name":"Martin R. Weiser","orcid":"https://orcid.org/0000-0002-9577-7984","observed_orcids":["https://orcid.org/0000-0002-9577-7984"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin R. Weiser","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026215879","display_name":"Melissa S. Pessin","orcid":"https://orcid.org/0000-0003-3990-6494","observed_orcids":["https://orcid.org/0000-0003-3990-6494"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa S. Pessin","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037120205","display_name":"Leonard B. Saltz","orcid":"https://orcid.org/0000-0001-8353-4670","observed_orcids":["https://orcid.org/0000-0001-8353-4670"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonard Saltz","raw_affiliation_strings":["From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Gastrointestinal Oncology Service, Department of Medicine, Department of Surgery, and Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":null,"apc_paid":null,"fwci":2.7126,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.91827859,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"6","first_page":"907","last_page":"913"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.7759000062942505,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.7759000062942505,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.10360000282526016,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.07620000094175339,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carcinoembryonic-antigen","display_name":"carcinoembryonic antigen","score":1.0},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.890999972820282},{"id":"https://openalex.org/keywords/postoperative-follow-up","display_name":"postoperative follow-up","score":0.6579999923706055},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.6729999780654907},{"id":"https://openalex.org/keywords/r0-resection","display_name":"R0 resection","score":0.8880000114440918},{"id":"https://openalex.org/keywords/upper-limit-of-normal","display_name":"upper limit of normal","score":0.5709999799728394},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.935488224029541},{"id":"https://openalex.org/C2777387746","wikidata":"https://www.wikidata.org/wiki/Q769706","display_name":"Carcinoembryonic antigen","level":3,"score":0.9316911697387695},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6567227840423584},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5923550724983215},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5774348378181458},{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.5411502718925476},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.5086575150489807},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5071907043457031},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4673961102962494},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22122350335121155},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002272","descriptor_name":"Carcinoembryonic Antigen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005189","descriptor_name":"False Positive Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.6004/jnccn.2014.0085","doi":"https://doi.org/10.6004/jnccn.2014.0085","is_oa":false,"landing_page_url":"https://doi.org/10.6004/jnccn.2014.0085","pdf_url":null,"source":{"id":"https://openalex.org/S935620192","display_name":"Journal of the National Comprehensive Cancer Network","issn_l":"1540-1405","issn":["1540-1405","1540-1413"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4324004213","host_organization_name":"National Comprehensive Cancer","host_organization_lineage":["https://openalex.org/P4324004213"],"host_organization_lineage_names":["National Comprehensive Cancer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Comprehensive Cancer Network","raw_type":"journal-article"},{"id":"pmid:24925201","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24925201","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Comprehensive Cancer Network : JNCCN","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8409326","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8409326","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Natl Compr Canc Netw","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8409326","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8409326","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Natl Compr Canc Netw","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1985701084","https://openalex.org/W2004102690","https://openalex.org/W2038722446","https://openalex.org/W2039282651","https://openalex.org/W2075565351","https://openalex.org/W2122078852","https://openalex.org/W2142571160","https://openalex.org/W2160246822"],"related_works":["https://openalex.org/W4388667524","https://openalex.org/W2052722087","https://openalex.org/W2443623894","https://openalex.org/W2997418968","https://openalex.org/W2081615235","https://openalex.org/W2080686578","https://openalex.org/W2921639060","https://openalex.org/W2608585935","https://openalex.org/W2077875595","https://openalex.org/W2626031145"],"abstract_inverted_index":{"Routine":[0],"monitoring":[1],"of":[2,18,24,35,51,85,94,104,107,129,151,191,199],"carcinoembryonic":[3],"antigen":[4],"(CEA)":[5],"levels":[6,224],"is":[7],"standard":[8],"in":[9,65,188,202],"patients":[10,45,157],"with":[11,114,132,146,158,231],"resected":[12],"colorectal":[13],"cancer":[14,232],"(CRC).":[15],"The":[16],"incidence":[17],"false-positives":[19],"and":[20,57,60,97,173,220],"the":[21,69,105,189],"upper":[22],"limits":[23],"false-positive":[25,83,160],"elevations":[26,140],"have":[27],"not":[28],"been":[29],"previously":[30],"well":[31],"characterized.":[32],"A":[33],"search":[34],"medical":[36],"records":[37],"at":[38],"Memorial":[39],"Sloan-Kettering":[40],"Cancer":[41],"Center":[42],"identified":[43],"728":[44],"who":[46,61],"underwent":[47],"an":[48,63],"R0":[49],"resection":[50],"locoregional":[52],"CRC":[53],"between":[54],"January":[55],"2003":[56],"December":[58],"2012":[59],"had":[62,81,89,99,118,139,167],"increase":[64],"CEA":[66,76,86,122,127,161,185,200,223],"level":[67,123,128,150,162],"above":[68],"normal":[70,74],"range":[71,190,204],"after":[72],"a":[73,82,90,100,108,119,147,182],"perioperative":[75],"level.":[77],"Of":[78,112,154],"these,":[79],"358":[80],"elevation":[84,92,102,124,176,201],"level,":[87],"335":[88],"true-positive":[91,101],"indicative":[93,103],"recurrent":[95],"CRC,":[96],"35":[98,179,227],"development":[106],"new,":[109],"non-CRC":[110],"malignancy.":[111],"those":[113],"false":[115],"elevations,":[116,163],"111":[117],"single":[120],"isolated":[121],"(median":[125],"highest":[126,149],"5.5":[130],"ng/mL)":[131],"no":[133,174],"further":[134],"abnormal":[135],"measurements,":[136],"whereas":[137],"247":[138,156],"on":[141],"2":[142],"or":[143],"more":[144],"readings,":[145],"median":[148],"6.7":[152],"ng/mL.":[153],"these":[155],"confirmed":[159,175,222],"only":[164],"5":[165,192],"(2%)":[166],"measurements":[168],"greater":[169,177,214,225],"than":[170,178,215,226],"15":[171,194,216],"ng/mL,":[172],"ng/mL":[180,195,217,228],"was":[181],"false-positive.":[183],"False-positive":[184,212],"test":[186],"results":[187,213],"to":[193],"are":[196,218],"common.":[197],"Confirmation":[198],"this":[203],"before":[205],"initiating":[206],"imaging":[207],"studies":[208],"may":[209],"be":[210],"appropriate.":[211],"rare,":[219],"all":[221],"were":[229],"associated":[230],"recurrence.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}