{"id":"https://openalex.org/W2301893286","doi":"https://doi.org/10.1152/jn.2001.85.6.2545","title":"Progression in Neuronal Processing for Saccadic Eye Movements From Parietal Cortex Area LIP to Superior Colliculus","display_name":"Progression in Neuronal Processing for Saccadic Eye Movements From Parietal Cortex Area LIP to Superior Colliculus","publication_year":2001,"publication_date":"2001-06-01","ids":{"openalex":"https://openalex.org/W2301893286","doi":"https://doi.org/10.1152/jn.2001.85.6.2545","mag":"2301893286","pmid":"https://pubmed.ncbi.nlm.nih.gov/11387400"},"language":"en","primary_location":{"id":"doi:10.1152/jn.2001.85.6.2545","doi":"https://doi.org/10.1152/jn.2001.85.6.2545","is_oa":false,"landing_page_url":"https://doi.org/10.1152/jn.2001.85.6.2545","pdf_url":null,"source":{"id":"https://openalex.org/S142952003","display_name":"Journal of Neurophysiology","issn_l":"0022-3077","issn":["0022-3077","1522-1598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurophysiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041894266","display_name":"Martin Par\u00e9","orcid":"https://orcid.org/0000-0001-6422-3359","observed_orcids":["https://orcid.org/0000-0001-6422-3359"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210139686","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Par\u00e9","raw_affiliation_strings":["Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112174135","display_name":"Robert H. Wurtz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210139686","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert H. Wurtz","raw_affiliation_strings":["Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.3682,"has_fulltext":false,"cited_by_count":174,"citation_normalized_percentile":{"value":0.94569112,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"85","issue":"6","first_page":"2545","last_page":"2562"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.8852999806404114,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.8852999806404114,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.06560000032186508,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/saccades","display_name":"saccades","score":0.9950000047683716},{"id":"https://openalex.org/keywords/lateral-intraparietal-area","display_name":"lateral intraparietal area","score":0.9890000224113464},{"id":"https://openalex.org/keywords/superior-colliculus","display_name":"superior colliculus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/delay-activity","display_name":"delay activity","score":0.6650000214576721},{"id":"https://openalex.org/keywords/antidromic-activation","display_name":"antidromic activation","score":0.7720000147819519},{"id":"https://openalex.org/keywords/go-no-go-task","display_name":"go/no-go task","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C2779524336","wikidata":"https://www.wikidata.org/wiki/Q369503","display_name":"Saccade","level":3,"score":0.8592387437820435},{"id":"https://openalex.org/C2781416072","wikidata":"https://www.wikidata.org/wiki/Q1109417","display_name":"Superior colliculus","level":2,"score":0.7530962228775024},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6686474084854126},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.6599324941635132},{"id":"https://openalex.org/C11054436","wikidata":"https://www.wikidata.org/wiki/Q7396580","display_name":"Saccadic masking","level":3,"score":0.6320801377296448},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6063318252563477},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.5366001129150391},{"id":"https://openalex.org/C153050134","wikidata":"https://www.wikidata.org/wiki/Q760256","display_name":"Eye movement","level":2,"score":0.5365560054779053},{"id":"https://openalex.org/C6757342","wikidata":"https://www.wikidata.org/wiki/Q3486606","display_name":"Posterior parietal cortex","level":2,"score":0.44944480061531067},{"id":"https://openalex.org/C146249460","wikidata":"https://www.wikidata.org/wiki/Q2914991","display_name":"Fixation (population genetics)","level":3,"score":0.44646477699279785},{"id":"https://openalex.org/C2779345533","wikidata":"https://www.wikidata.org/wiki/Q75785","display_name":"Visual cortex","level":2,"score":0.4114161431789398},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17039233446121216},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.12431326508522034},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.0771297812461853},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008253","descriptor_name":"Macaca mulatta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010296","descriptor_name":"Parietal Lobe","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D010296","descriptor_name":"Parietal Lobe","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010775","descriptor_name":"Photic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011597","descriptor_name":"Psychomotor Performance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012438","descriptor_name":"Saccades","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013477","descriptor_name":"Superior Colliculi","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013477","descriptor_name":"Superior Colliculi","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1152/jn.2001.85.6.2545","doi":"https://doi.org/10.1152/jn.2001.85.6.2545","is_oa":false,"landing_page_url":"https://doi.org/10.1152/jn.2001.85.6.2545","pdf_url":null,"source":{"id":"https://openalex.org/S142952003","display_name":"Journal of Neurophysiology","issn_l":"0022-3077","issn":["0022-3077","1522-1598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurophysiology","raw_type":"journal-article"},{"id":"pmid:11387400","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11387400","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurophysiology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.530.8482","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.530.8482","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.lsr-web.net/Assets/NEIPages/BobWurtz/pdfs/PareWur01.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W1511712482","https://openalex.org/W1545365849","https://openalex.org/W1569395231","https://openalex.org/W1596940277","https://openalex.org/W1602563799","https://openalex.org/W1608766894","https://openalex.org/W1642141456","https://openalex.org/W1754695201","https://openalex.org/W1784695092","https://openalex.org/W1828552290","https://openalex.org/W1834488362","https://openalex.org/W1836954933","https://openalex.org/W1848299952","https://openalex.org/W1858478925","https://openalex.org/W1875187353","https://openalex.org/W1886830920","https://openalex.org/W1897609037","https://openalex.org/W1938730539","https://openalex.org/W1945299547","https://openalex.org/W1970727555","https://openalex.org/W1974864585","https://openalex.org/W1975399791","https://openalex.org/W1980871601","https://openalex.org/W1990534247","https://openalex.org/W2011494714","https://openalex.org/W2016527110","https://openalex.org/W2020715512","https://openalex.org/W2025670690","https://openalex.org/W2033435873","https://openalex.org/W2033532788","https://openalex.org/W2040955687","https://openalex.org/W2047889874","https://openalex.org/W2058395663","https://openalex.org/W2071422046","https://openalex.org/W2075997894","https://openalex.org/W2085174376","https://openalex.org/W2086105634","https://openalex.org/W2088367999","https://openalex.org/W2093642963","https://openalex.org/W2104663113","https://openalex.org/W2106870673","https://openalex.org/W2107886772","https://openalex.org/W2113705163","https://openalex.org/W2114410849","https://openalex.org/W2123086804","https://openalex.org/W2129460351","https://openalex.org/W2129575185","https://openalex.org/W2130508503","https://openalex.org/W2135672633","https://openalex.org/W2137228404","https://openalex.org/W2143325267","https://openalex.org/W2144200546","https://openalex.org/W2150367061","https://openalex.org/W2151783777","https://openalex.org/W2177428647","https://openalex.org/W2181613865","https://openalex.org/W2184452647","https://openalex.org/W2271263590","https://openalex.org/W2279931900","https://openalex.org/W2283824430","https://openalex.org/W2290046961","https://openalex.org/W2307321672","https://openalex.org/W2337518633","https://openalex.org/W2400038826","https://openalex.org/W2411927066","https://openalex.org/W2414443889","https://openalex.org/W2426300448","https://openalex.org/W2438667580","https://openalex.org/W3036021473","https://openalex.org/W4238614223","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2129460351","https://openalex.org/W1858478925","https://openalex.org/W7098032735","https://openalex.org/W1897609037","https://openalex.org/W1995767122","https://openalex.org/W7099951475","https://openalex.org/W2181613865","https://openalex.org/W4388974873","https://openalex.org/W2751219300","https://openalex.org/W2283824430"],"abstract_inverted_index":{"Neurons":[0],"in":[1,25,41,97,104,156,160,233,237,313,319,361,371,375,386],"both":[2,269],"the":[3,9,14,18,28,42,55,73,109,138,146,162,165,178,181,186,193,197,203,213,221,240,244,278,293,317,320,337,344,350,355,373,387],"lateral":[4],"intraparietal":[5],"area":[6,48,364],"(LIP)":[7],"of":[8,17,27,30,58,68,115,124,140,148,164,185,196,202,224,239,268,303,339,357],"monkey":[10,245],"parietal":[11,362],"cortex":[12,363],"and":[13,86,90,103,127,142,180,215,261,271,299,332],"intermediate":[15,322],"layers":[16,323],"superior":[19],"colliculus":[20],"(SC)":[21],"are":[22],"activated":[23],"well":[24],"advance":[26,279],"initiation":[29],"saccadic":[31],"eye":[32],"movements.":[33],"To":[34],"determine":[35],"whether":[36],"there":[37],"is":[38],"a":[39,82,149,225,228,235,249,252,283,301,325,333,367,383],"progression":[40],"covert":[43],"processing":[44,359,369,389],"for":[45,390],"saccades":[46],"from":[47,72,328],"LIP":[49,59,89,116,141,187,214,270,286,304,345,365],"to":[50,100,220,247,251,257,281,336,349,366],"SC,":[51,372],"we":[52,77,136,210,379],"systematically":[53],"compared":[54,78],"discharge":[56,315],"properties":[57],"output":[60],"neurons":[61,70,92,117,126,287,305,318,346],"identified":[62],"by":[63,152,277],"antidromic":[64],"activation":[65],"with":[66],"those":[67,201],"SC":[69,91,125,143,204,216,272,297,321],"collected":[71],"same":[74],"monkeys.":[75],"First,":[76],"activity":[79,107,114,144,155,183,218,267,377],"patterns":[80],"during":[81,108],"delayed":[83,157,229],"saccade":[84,113,158,226,231,250,342],"task":[85],"found":[87],"that":[88,123,378],"showed":[93,324],"an":[94,340],"extensive":[95],"overlap":[96,312],"their":[98,105,154,314],"responses":[99],"visual":[101,150,166,198,254,330],"stimuli":[102],"sustained":[106,170,194,329],"delay":[110,133,179,217,266],"period.":[111],"The":[112,264],"was,":[118],"however,":[119],"remarkably":[120],"weaker":[121],"than":[122,296,343,353],"never":[128],"occurred":[129],"without":[130],"any":[131],"preceding":[132],"activity.":[134],"Second,":[135],"assessed":[137],"dependence":[139],"on":[145,192,292],"presence":[147,195],"stimulus":[151,167,242,255],"contrasting":[153],"trials":[159],"which":[161,234],"presentation":[163],"was":[168,306],"either":[169,246],"(visual":[171],"trials)":[172],"or":[173,256],"brief":[174],"(memory":[175],"trials).":[176],"Both":[177],"presaccadic":[182],"levels":[184],"neuronal":[188,205,273,376,388],"sample":[189,206],"significantly":[190,275,289,307],"depended":[191],"stimulus,":[199],"whereas":[200],"did":[207],"not.":[208],"Third,":[209],"examined":[211],"how":[212],"relates":[219],"future":[222],"production":[223,338],"using":[227],"GO/NOGO":[230],"task,":[232],"change":[236],"color":[238],"fixation":[241],"instructed":[243],"make":[248,282],"peripheral":[253],"withhold":[258],"its":[259],"response":[260,294],"maintain":[262],"fixation.":[263],"average":[265],"samples":[274],"increased":[276],"instruction":[280,295],"saccade,":[284],"but":[285],"were":[288],"less":[290],"dependent":[291],"neurons,":[298],"only":[300],"minority":[302],"modulated.":[308],"Thus":[309],"despite":[310],"some":[311],"properties,":[316],"greater":[326],"independence":[327],"stimulation":[331],"tighter":[334],"relationship":[335],"impending":[341],"supplying":[347],"inputs":[348],"SC.":[351],"Rather":[352],"representing":[354],"transmission":[356],"one":[358],"stage":[360,370],"subsequent":[368],"differences":[374],"observed":[380],"suggest":[381],"instead":[382],"progressive":[384],"evolution":[385],"saccades.":[391]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":9},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}