{"id":"https://openalex.org/W2301649294","doi":null,"title":"A morphological and functional characterization of Bombyx mori larval midgut cells in culture","display_name":"A morphological and functional characterization of Bombyx mori larval midgut cells in culture","publication_year":2007,"publication_date":"2007-11-01","ids":{"openalex":"https://openalex.org/W2301649294","mag":"2301649294"},"language":"en","primary_location":{"id":"pmh:oai:isj.unimo.it:article/151","doi":null,"is_oa":true,"landing_page_url":"https://isj.unimore.it/index.php/ISJ/article/view/151","pdf_url":"https://isj.unimore.it/index.php/ISJ/article/download/151/67","source":{"id":"https://openalex.org/S2481433337","display_name":"Invertebrate survival journal","issn_l":"1824-307X","issn":["1824-307X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317690","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/P4310317690"],"host_organization_lineage_names":["University of Modena and Reggio Emilia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1824-307X","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://isj.unimore.it/index.php/ISJ/article/download/151/67","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063447126","display_name":"Gaia Cermenati","orcid":"https://orcid.org/0000-0003-4729-9276","observed_orcids":["https://orcid.org/0000-0003-4729-9276"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Cermenati","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"P Corti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Corti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008287607","display_name":"Silvia Caccia","orcid":"https://orcid.org/0000-0003-1954-7180","observed_orcids":["https://orcid.org/0000-0003-1954-7180"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Caccia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071840525","display_name":"Barbara Giordana","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Giordana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5030240387","display_name":"Morena Casartelli","orcid":"https://orcid.org/0000-0002-1413-7660","observed_orcids":["https://orcid.org/0000-0002-1413-7660"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Casartelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5522,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.65522185,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.5903000235557556,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.5903000235557556,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14048","display_name":"Silkworms and Sericulture Research","score":0.08799999952316284,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.07999999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bombyx-mori","display_name":"Bombyx mori","score":0.9950000047683716},{"id":"https://openalex.org/keywords/midgut-epithelium","display_name":"midgut epithelium","score":0.8320000171661377},{"id":"https://openalex.org/keywords/transcytosis","display_name":"transcytosis","score":0.8399999737739563},{"id":"https://openalex.org/keywords/columnar-epithelial-cells","display_name":"columnar cells","score":0.7599999904632568},{"id":"https://openalex.org/keywords/goblet-cells","display_name":"goblet cells","score":1.0},{"id":"https://openalex.org/keywords/stem-cell-differentiation","display_name":"stem cell differentiation","score":0.5519999861717224},{"id":"https://openalex.org/keywords/20-hydroxyecdysone","display_name":"20-hydroxyecdysone","score":0.9549999833106995},{"id":"https://openalex.org/keywords/cell-polarity","display_name":"cell polarity","score":0.652999997138977},{"id":"https://openalex.org/keywords/brush-border","display_name":"brush border","score":0.6819999814033508},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.8109999895095825},{"id":"https://openalex.org/keywords/microtubules","display_name":"microtubules","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cd13","display_name":"CD13","score":0.9850000143051147},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":1.0},{"id":"https://openalex.org/keywords/protein-trafficking","display_name":"protein trafficking","score":0.7160000205039978},{"id":"https://openalex.org/keywords/in-vitro-cell-culture","display_name":"in vitro cell culture","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C150149183","wikidata":"https://www.wikidata.org/wiki/Q1940081","display_name":"Midgut","level":3,"score":0.9560596942901611},{"id":"https://openalex.org/C2778487026","wikidata":"https://www.wikidata.org/wiki/Q134747","display_name":"Bombyx mori","level":3,"score":0.8839353322982788},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.685687243938446},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46309876441955566},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.43716520071029663},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3837518095970154},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.23379826545715332},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08850207924842834},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.07662796974182129},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0718957781791687},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.05803486704826355}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:isj.unimo.it:article/151","doi":null,"is_oa":true,"landing_page_url":"https://isj.unimore.it/index.php/ISJ/article/view/151","pdf_url":"https://isj.unimore.it/index.php/ISJ/article/download/151/67","source":{"id":"https://openalex.org/S2481433337","display_name":"Invertebrate survival journal","issn_l":"1824-307X","issn":["1824-307X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317690","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/P4310317690"],"host_organization_lineage_names":["University of Modena and Reggio Emilia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1824-307X","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:de11f7f6e7004ba684383295560f2e77","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/de11f7f6e7004ba684383295560f2e77","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Invertebrate Survival Journal, Vol 4, Iss 2, Pp 119-126 (2007)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:df0ac0fedfdf46bbbea6d1582ed95541","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/df0ac0fedfdf46bbbea6d1582ed95541","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Invertebrate Survival Journal, Vol 4, Iss 2 (2007)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:isj.unimo.it:article/151","doi":null,"is_oa":true,"landing_page_url":"https://isj.unimore.it/index.php/ISJ/article/view/151","pdf_url":"https://isj.unimore.it/index.php/ISJ/article/download/151/67","source":{"id":"https://openalex.org/S2481433337","display_name":"Invertebrate survival journal","issn_l":"1824-307X","issn":["1824-307X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","ddh","doaj","dongbi-c","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317690","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/P4310317690"],"host_organization_lineage_names":["University of Modena and Reggio Emilia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1824-307X","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2301649294.pdf","grobid_xml":"https://content.openalex.org/works/W2301649294.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W613851713","https://openalex.org/W1570939393","https://openalex.org/W1578236466","https://openalex.org/W1945719004","https://openalex.org/W1974852894","https://openalex.org/W1999716819","https://openalex.org/W1999855229","https://openalex.org/W2000434903","https://openalex.org/W2000623142","https://openalex.org/W2001499222","https://openalex.org/W2001838240","https://openalex.org/W2002216668","https://openalex.org/W2002612414","https://openalex.org/W2005993913","https://openalex.org/W2006626412","https://openalex.org/W2010550147","https://openalex.org/W2022068090","https://openalex.org/W2022767874","https://openalex.org/W2025863678","https://openalex.org/W2042558793","https://openalex.org/W2047871421","https://openalex.org/W2057600332","https://openalex.org/W2062095186","https://openalex.org/W2064226544","https://openalex.org/W2065807538","https://openalex.org/W2067725621","https://openalex.org/W2080097642","https://openalex.org/W2081653221","https://openalex.org/W2089606089","https://openalex.org/W2126582065","https://openalex.org/W2128635872","https://openalex.org/W2133624569","https://openalex.org/W2140080961","https://openalex.org/W2223518195","https://openalex.org/W2247545072","https://openalex.org/W2490327069"],"related_works":["https://openalex.org/W6959774497","https://openalex.org/W2032237681","https://openalex.org/W2042558793","https://openalex.org/W2002563791","https://openalex.org/W7210945806","https://openalex.org/W2778707785","https://openalex.org/W2282228283","https://openalex.org/W2520349015","https://openalex.org/W2089606089","https://openalex.org/W2057600332"],"abstract_inverted_index":{"Recent":[0],"studies":[1],"have":[2],"shown":[3],"that":[4,189],"Bombyx":[5],"mori":[6,68],"larval":[7],"midgut":[8,47,56,105],"can":[9],"transport":[10,53,223],"proteins":[11,219],"unaltered":[12],"following":[13],"the":[14,31,43,88,98,104,112,142,152,162,169,172,176,197],"transcellular":[15],"pathway":[16],"by":[17],"transcytosis.":[18],"The":[19,207],"numerous":[20],"steps":[21],"involved":[22,193],"in":[23,30,49,58,71,103,110,119,148,151,194,196,205,211],"this":[24,40],"complex":[25],"process":[26],"are":[27,202],"still":[28],"unknown":[29],"insect":[32],"midgut,":[33],"and":[34,78,95,116,146,165,184,199],"a":[35,131,157],"promising":[36],"tool":[37],"to":[38,84,171,215],"elucidate":[39],"aspect":[41],"is":[42],"availability":[44],"of":[45,87,175],"single":[46],"cells":[48,57,64,90,108,129,179,209],"culture":[50,59,212],"suitable":[51],"for":[52],"experiments.":[54],"Mature":[55],"were":[60,91,125,213],"obtained":[61],"from":[62,66,168],"stem":[63],"isolated":[65],"B.":[67],"larvae":[69],"cultured":[70,89],"Grace\u2019s":[72],"medium":[73],"supplemented":[74],"with":[75,136,220],"20-hydroxyecdysone":[76],"(20-HE)":[77],"\u03b1-arylphorin.":[79],"After":[80],"three":[81],"weeks,":[82],"up":[83],"60":[85],"%":[86],"differentiated":[92,210],"into":[93],"columnar":[94,208],"goblet":[96],"cells,":[97],"two":[99,191,217],"predominant":[100],"cell":[101,153],"types":[102],"epithelium.":[106],"These":[107],"presented":[109],"vitro":[111],"same":[113],"shape,":[114],"morphology":[115],"polarity":[117],"recorded":[118],"vivo,":[120],"even":[121],"if":[122],"their":[123],"dimensions":[124],"slightly":[126],"reduced.":[127],"Columnar":[128],"displayed":[130,181],"well":[132],"developed":[133],"cytoskeletal":[134],"arrangement,":[135],"actin":[137],"filaments":[138,150],"highly":[139],"organized":[140],"within":[141],"thick":[143],"brush":[144,163],"border":[145,164],"distributed":[147],"faint":[149],"cytoplasm.":[154],"Microtubules":[155],"formed":[156],"substantial":[158],"net":[159],"just":[160],"beneath":[161],"ran":[166],"longitudinally":[167],"apical":[170],"basal":[173],"pole":[174],"cell.":[177],"Cultured":[178],"homogenates":[180],"aminopeptidase":[182],"N":[183],"alkaline":[185],"phosphatase":[186],"activity,":[187],"proving":[188],"these":[190],"enzymes,":[192],"vivo":[195],"intermediate":[198],"final":[200],"digestion,":[201],"expressed":[203],"also":[204],"vitro.":[206],"able":[214],"internalize":[216],"model":[218],"quite":[221],"different":[222],"rates.":[224]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-03T13:16:28.481748","created_date":"2016-06-24T00:00:00"}