{"id":"https://openalex.org/W2301577241","doi":"https://doi.org/10.1039/c5ay03397g","title":"Rapid detection of Dam methyltransferase activity based on the exonuclease III-assisted isothermal amplification cycle","display_name":"Rapid detection of Dam methyltransferase activity based on the exonuclease III-assisted isothermal amplification cycle","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2301577241","doi":"https://doi.org/10.1039/c5ay03397g","mag":"2301577241"},"language":"en","primary_location":{"id":"doi:10.1039/c5ay03397g","doi":"https://doi.org/10.1039/c5ay03397g","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c5ay03397g","pdf_url":null,"source":{"id":"https://openalex.org/S170358085","display_name":"Analytical Methods","issn_l":"1759-9660","issn":["1759-9660","1759-9679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Methods","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100372223","display_name":"Xue Li","orcid":"https://orcid.org/0000-0002-6856-2494","observed_orcids":["https://orcid.org/0000-0002-6856-2494"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xue Li","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100532332","display_name":"Xie Zhipeng","orcid":"https://orcid.org/0000-0003-1340-391X","observed_orcids":["https://orcid.org/0000-0003-1340-391X","https://orcid.org/0000-0002-0347-5867"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhipeng Xie","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100392035","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0002-6346-2216","observed_orcids":["https://orcid.org/0000-0002-6346-2216"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102864137","display_name":"Yunlei Zhou","orcid":"https://orcid.org/0000-0003-2629-3836","observed_orcids":["https://orcid.org/0000-0003-2629-3836"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yunlei Zhou","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056223311","display_name":"Huanshun Yin","orcid":"https://orcid.org/0000-0002-5022-0314","observed_orcids":["https://orcid.org/0000-0002-5022-0314"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huanshun Yin","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050166961","display_name":"Zhiqing Yang","orcid":"https://orcid.org/0000-0003-2017-6583","observed_orcids":["https://orcid.org/0000-0003-2017-6583"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiqing Yang","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040771650","display_name":"Shiyun Ai","orcid":"https://orcid.org/0000-0003-0449-3677","observed_orcids":["https://orcid.org/0000-0003-0449-3677","https://orcid.org/0000-0001-8580-6852","https://orcid.org/0000-0003-2446-4590"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shiyun Ai","raw_affiliation_strings":["College of Chemistry and Material Science","PR China","Shandong Agricultural University","Taian","College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Material Science","institution_ids":[]},{"raw_affiliation_string":"PR China","institution_ids":[]},{"raw_affiliation_string":"Shandong Agricultural University","institution_ids":["https://openalex.org/I74485261"]},{"raw_affiliation_string":"Taian","institution_ids":[]},{"raw_affiliation_string":"College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China","institution_ids":["https://openalex.org/I74485261"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5040771650","https://openalex.org/A5102864137"],"corresponding_institution_ids":["https://openalex.org/I74485261"],"apc_list":null,"apc_paid":null,"fwci":1.0402,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.76499736,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"8","issue":"13","first_page":"2771","last_page":"2777"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dam-methyltransferase","display_name":"Dam methyltransferase","score":0.9660000205039978},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7889999747276306},{"id":"https://openalex.org/keywords/exonuclease-iii","display_name":"exonuclease III","score":0.9559999704360962},{"id":"https://openalex.org/keywords/isothermal-amplification","display_name":"isothermal amplification","score":0.9599999785423279},{"id":"https://openalex.org/keywords/electrochemical-detection","display_name":"electrochemical detection","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C2777501222","wikidata":"https://www.wikidata.org/wiki/Q411664","display_name":"Exonuclease","level":4,"score":0.8579740524291992},{"id":"https://openalex.org/C60635243","wikidata":"https://www.wikidata.org/wiki/Q6675780","display_name":"Loop-mediated isothermal amplification","level":3,"score":0.8126695156097412},{"id":"https://openalex.org/C133347239","wikidata":"https://www.wikidata.org/wiki/Q486921","display_name":"Isothermal process","level":2,"score":0.776007890701294},{"id":"https://openalex.org/C2781243718","wikidata":"https://www.wikidata.org/wiki/Q5420625","display_name":"Exonuclease III","level":4,"score":0.5972069501876831},{"id":"https://openalex.org/C91965660","wikidata":"https://www.wikidata.org/wiki/Q415875","display_name":"Methyltransferase","level":4,"score":0.5882852077484131},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5030173659324646},{"id":"https://openalex.org/C2779979206","wikidata":"https://www.wikidata.org/wiki/Q1154602","display_name":"DNA methyltransferase","level":5,"score":0.4698321521282196},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.323819100856781},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.2509807348251343},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24491971731185913},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.229562908411026},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12307041883468628},{"id":"https://openalex.org/C2756471","wikidata":"https://www.wikidata.org/wiki/Q206286","display_name":"DNA polymerase","level":3,"score":0.09125468134880066},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.08527815341949463},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08508613705635071},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.05976775288581848},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/c5ay03397g","doi":"https://doi.org/10.1039/c5ay03397g","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c5ay03397g","pdf_url":null,"source":{"id":"https://openalex.org/S170358085","display_name":"Analytical Methods","issn_l":"1759-9660","issn":["1759-9660","1759-9679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Methods","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.8399999737739563,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W646508359","https://openalex.org/W1821797507","https://openalex.org/W1896820664","https://openalex.org/W1967609937","https://openalex.org/W1971508343","https://openalex.org/W1976079395","https://openalex.org/W1983480343","https://openalex.org/W1985814033","https://openalex.org/W1986046326","https://openalex.org/W1987600326","https://openalex.org/W1990630287","https://openalex.org/W1995236787","https://openalex.org/W1998831527","https://openalex.org/W2008559140","https://openalex.org/W2008820162","https://openalex.org/W2010298880","https://openalex.org/W2011165111","https://openalex.org/W2012036278","https://openalex.org/W2012508649","https://openalex.org/W2013286874","https://openalex.org/W2014126625","https://openalex.org/W2017515560","https://openalex.org/W2020592946","https://openalex.org/W2030277422","https://openalex.org/W2033294834","https://openalex.org/W2036031444","https://openalex.org/W2049989960","https://openalex.org/W2052667621","https://openalex.org/W2063680450","https://openalex.org/W2076257614","https://openalex.org/W2078653411","https://openalex.org/W2080620002","https://openalex.org/W2093381450","https://openalex.org/W2093468673","https://openalex.org/W2096361826","https://openalex.org/W2121367410","https://openalex.org/W2165416642","https://openalex.org/W2321263475","https://openalex.org/W2323528109","https://openalex.org/W2566881132"],"related_works":["https://openalex.org/W2093468673","https://openalex.org/W2352839577","https://openalex.org/W4302275604","https://openalex.org/W2033294834","https://openalex.org/W2049989960","https://openalex.org/W2902717197","https://openalex.org/W2474450905","https://openalex.org/W2111850268","https://openalex.org/W2171076287","https://openalex.org/W2300212441"],"abstract_inverted_index":{"Novel":[0],"and":[1],"rapid":[2],"electrochemical":[3],"strategies":[4],"for":[5],"Dam":[6],"methyltransferase":[7],"activity":[8],"detection":[9],"based":[10],"on":[11],"the":[12],"exonuclease":[13],"III":[14],"assisted":[15],"isothermal":[16],"amplification":[17],"cycle":[18],"were":[19],"developed.":[20]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-11T09:32:39.932853","created_date":"2016-06-24T00:00:00"}