{"id":"https://openalex.org/W2301520264","doi":null,"title":"Comprehensive Analysis of Risk Factors in Offspring of Type 2 Diabetic Patients","display_name":"Comprehensive Analysis of Risk Factors in Offspring of Type 2 Diabetic Patients","publication_year":2010,"publication_date":"2010-12-21","ids":{"openalex":"https://openalex.org/W2301520264","mag":"2301520264"},"language":"en","primary_location":{"id":"mag:2301520264","doi":null,"is_oa":false,"landing_page_url":"https://ediss.sub.uni-hamburg.de/volltexte/2010/4939/pdf/Dissertation_Vossen.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023470192","display_name":"Michaela Vossen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"M. Vossen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5023470192"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.27941391,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.6093999743461609,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.6093999743461609,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.10130000114440918,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.07999999821186066,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.6439999938011169},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.8859999775886536},{"id":"https://openalex.org/keywords/plasma-phospholipids","display_name":"plasma phospholipids","score":0.7870000004768372},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8259999752044678},{"id":"https://openalex.org/keywords/postprandial-metabolism","display_name":"postprandial metabolism","score":0.8029999732971191},{"id":"https://openalex.org/keywords/oral-glucose-tolerance-test","display_name":"oral glucose tolerance test","score":0.7910000085830688},{"id":"https://openalex.org/keywords/oral-fat-tolerance-test","display_name":"oral fat tolerance test","score":0.9660000205039978},{"id":"https://openalex.org/keywords/plasminogen-activator-inhibitor-1","display_name":"plasminogen activator inhibitor-1","score":0.9739999771118164},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.765999972820282},{"id":"https://openalex.org/keywords/metabolic-profiling","display_name":"metabolite profiling","score":0.718999981880188}],"concepts":[{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.7531616687774658},{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.7355759739875793},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7229778170585632},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7025886178016663},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.6724923849105835},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6095983982086182},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.562257707118988},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5229119658470154},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4865383207798004},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4724966585636139},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.4646083414554596},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17394864559173584},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.13340961933135986},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2301520264","doi":null,"is_oa":false,"landing_page_url":"https://ediss.sub.uni-hamburg.de/volltexte/2010/4939/pdf/Dissertation_Vossen.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":138,"referenced_works":["https://openalex.org/W31446609","https://openalex.org/W127818422","https://openalex.org/W163709562","https://openalex.org/W1483242733","https://openalex.org/W1544412212","https://openalex.org/W1570155932","https://openalex.org/W1808898926","https://openalex.org/W1854107545","https://openalex.org/W1893413717","https://openalex.org/W1909772243","https://openalex.org/W1914089044","https://openalex.org/W1955662609","https://openalex.org/W1957381122","https://openalex.org/W1965495310","https://openalex.org/W1966842587","https://openalex.org/W1966991669","https://openalex.org/W1968261040","https://openalex.org/W1970653898","https://openalex.org/W1976243392","https://openalex.org/W1979488931","https://openalex.org/W1980380307","https://openalex.org/W1980648524","https://openalex.org/W1981232461","https://openalex.org/W1989797259","https://openalex.org/W1989854139","https://openalex.org/W1990280336","https://openalex.org/W1991147447","https://openalex.org/W1992967451","https://openalex.org/W1994470496","https://openalex.org/W1999879148","https://openalex.org/W2000054651","https://openalex.org/W2001283080","https://openalex.org/W2001382309","https://openalex.org/W2002754483","https://openalex.org/W2003416763","https://openalex.org/W2004071453","https://openalex.org/W2006406271","https://openalex.org/W2006611449","https://openalex.org/W2009718837","https://openalex.org/W2011076773","https://openalex.org/W2016785044","https://openalex.org/W2017975097","https://openalex.org/W2020659754","https://openalex.org/W2021503045","https://openalex.org/W2021805559","https://openalex.org/W2023063219","https://openalex.org/W2028128288","https://openalex.org/W2028676438","https://openalex.org/W2030718882","https://openalex.org/W2031844721","https://openalex.org/W2032430567","https://openalex.org/W2034663971","https://openalex.org/W2034692800","https://openalex.org/W2036890526","https://openalex.org/W2038961236","https://openalex.org/W2039250890","https://openalex.org/W2046320949","https://openalex.org/W2047585934","https://openalex.org/W2048018726","https://openalex.org/W2049608785","https://openalex.org/W2051419940","https://openalex.org/W2051868844","https://openalex.org/W2052620776","https://openalex.org/W2053187448","https://openalex.org/W2053731083","https://openalex.org/W2054571412","https://openalex.org/W2058724069","https://openalex.org/W2061240655","https://openalex.org/W2061349644","https://openalex.org/W2063739794","https://openalex.org/W2064370899","https://openalex.org/W2067684598","https://openalex.org/W2067799426","https://openalex.org/W2068218521","https://openalex.org/W2072506456","https://openalex.org/W2074672488","https://openalex.org/W2076468162","https://openalex.org/W2077149049","https://openalex.org/W2078390930","https://openalex.org/W2079246886","https://openalex.org/W2079285443","https://openalex.org/W2081019976","https://openalex.org/W2083269055","https://openalex.org/W2095612977","https://openalex.org/W2096949413","https://openalex.org/W2101682092","https://openalex.org/W2103242651","https://openalex.org/W2104468045","https://openalex.org/W2109741059","https://openalex.org/W2110035765","https://openalex.org/W2111498906","https://openalex.org/W2114041992","https://openalex.org/W2114249119","https://openalex.org/W2115776356","https://openalex.org/W2115960319","https://openalex.org/W2120385990","https://openalex.org/W2121565483","https://openalex.org/W2121788167","https://openalex.org/W2125872855","https://openalex.org/W2125895299","https://openalex.org/W2130677536","https://openalex.org/W2135403536","https://openalex.org/W2139203772","https://openalex.org/W2140012993","https://openalex.org/W2140424137","https://openalex.org/W2142666508","https://openalex.org/W2143104968","https://openalex.org/W2143586387","https://openalex.org/W2144832958","https://openalex.org/W2146109620","https://openalex.org/W2148613010","https://openalex.org/W2149026447","https://openalex.org/W2150129204","https://openalex.org/W2151211184","https://openalex.org/W2151607624","https://openalex.org/W2151651725","https://openalex.org/W2151716502","https://openalex.org/W2151718403","https://openalex.org/W2153738368","https://openalex.org/W2159080529","https://openalex.org/W2159729794","https://openalex.org/W2159788200","https://openalex.org/W2160234571","https://openalex.org/W2167775693","https://openalex.org/W2169030912","https://openalex.org/W2171027756","https://openalex.org/W2172488527","https://openalex.org/W2185461071","https://openalex.org/W2211467290","https://openalex.org/W2289293388","https://openalex.org/W2334791394","https://openalex.org/W2416067122","https://openalex.org/W2417361765","https://openalex.org/W2477872031","https://openalex.org/W2483631733","https://openalex.org/W2739894177","https://openalex.org/W3021659692","https://openalex.org/W3137410270"],"related_works":["https://openalex.org/W2060410362","https://openalex.org/W2033654554","https://openalex.org/W2058724069","https://openalex.org/W2420992859","https://openalex.org/W4313478850","https://openalex.org/W2418849068","https://openalex.org/W2051862233","https://openalex.org/W1760127704","https://openalex.org/W4313821076","https://openalex.org/W2083479212"],"abstract_inverted_index":{"Individuals":[0],"with":[1,134,231],"at":[2],"least":[3],"one":[4],"type":[5,18,55,186,200,214],"2":[6,19,56,187,201,215],"diabetic":[7,202],"parent":[8],"have":[9],"a":[10,46,49,62,102,117,297],"substantially":[11],"higher":[12],"risk":[13,35,170,302],"of":[14,48,51,72,101,124,137,147,196,207,213,227],"developing":[15],"insulin":[16,232],"resistance,":[17],"diabetes":[20,57,188,216],"or":[21,189],"cardiovascular":[22,218,305],"diseases.":[23,306],"Thus,":[24],"these":[25],"individuals":[26],"can":[27],"be":[28],"used":[29,60,115],"not":[30],"only":[31],"to":[32,39,164,259],"identify":[33],"novel":[34],"markers":[36],"but":[37],"also":[38],"recognize":[40],"early":[41],"alterations":[42],"in":[43,131,176,193,222],"metabolism.":[44],"\r\nTherefore,":[45],"study":[47,245],"cohort":[50,195],"91":[52],"apparently":[53],"healthy":[54,184,197],"offspring":[58,198],"was":[59,129,163,235,285],"as":[61,105,255,270,272,296],"basis":[63,146],"for":[64,116,183,299,304],"this":[65,132],"work":[66],"which":[67,281],"comprised":[68],"the":[69,73,99,135,145,194,205,211,225,236,244,248,256,286],"biostatistical":[70,138],"analysis":[71],"given":[74],"dataset.":[75],"The":[76,111,121,140,160,241,278],"participants":[77],"were":[78,87,114,142],"invited":[79],"on":[80,144,157,247],"two":[81],"independent":[82],"test":[83,96,269],"days.":[84],"Plasma":[85],"samples":[86,113],"collected":[88],"before":[89],"and":[90,97,126,150,172,179,217,251,291,301],"after":[91,98],"an":[92,106,265,273],"oral":[93,107,266,274],"glucose":[94,267],"tolerance":[95,109,268,276],"consumption":[100],"fat-rich":[103],"breakfast":[104],"fat":[108,275],"test.":[110,277],"plasma":[112,178,228,261],"comprehensive":[118],"metabolic":[119],"profiling.":[120],"large":[122],"dataset":[123],"fasting":[125],"postprandial":[127,249],"data":[128],"analyzed":[130,284],"thesis":[133,155],"help":[136],"methods.":[139],"results":[141],"interpreted":[143],"current":[148],"knowledge":[149],"previously":[151,166],"published":[152],"data.":[153],"\r\nThis":[154],"focused":[156,246],"four":[158],"aspects.":[159],"first":[161],"aim":[162],"confirm":[165],"re-ported":[167],"association":[168,287],"between":[169,288],"factors":[171],"fatty":[173],"acids,":[174],"measured":[175],"total":[177],"major":[180],"phospholipid":[181],"species,":[182],"subjects,":[185],"cardiovas-cular":[190],"diseases":[191,219],"patients,":[192],"from":[199],"pa-tients.":[203],"Since":[204],"role":[206],"omega3-fatty":[208,229,289],"acids":[209,230,290],"during":[210,264],"development":[212],"remained":[220],"inconclusive":[221],"previous":[223],"studies,":[224],"associa-tion":[226],"resistance":[233],"parameters":[234],"second":[237],"as-pect":[238],"studied":[239],"here.":[240],"fact":[242],"that":[243],"state":[250],"in-sulin":[252],"action,":[253],"allowed,":[254],"third":[257],"aspect,":[258],"analyze":[260],"triacylglycerol":[262],"levels":[263],"well":[271],"fourth":[279],"aspect":[280],"has":[282],"been":[283],"ac-tive":[292],"plasminogen":[293],"activator":[294],"inhibitor-1":[295],"marker":[298],"fibrinolysis":[300],"factor":[303]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}
