{"id":"https://openalex.org/W2300769699","doi":null,"title":"Fructose Intake from Sugar-Sweetened Beverages and Acute Plasma Uric Acid Production","display_name":"Fructose Intake from Sugar-Sweetened Beverages and Acute Plasma Uric Acid Production","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2300769699","mag":"2300769699"},"language":"en","primary_location":{"id":"pmh:oai:alma.64OTAGO_INST:11396468660001891","doi":null,"is_oa":true,"landing_page_url":"https://ourarchive.otago.ac.nz/esploro/outputs/graduate/Fructose-Intake-from-Sugar-Sweetened-Beverages-and/9926478451401891","pdf_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396468650001891/13397058740001891","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Masters Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396468650001891/13397058740001891","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002791800","display_name":"Emma Louise Carran","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Emma Louise Carran","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5002791800"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sugar-sweetened-beverages","display_name":"sugar-sweetened beverages","score":0.9900000095367432},{"id":"https://openalex.org/keywords/plasma-uric-acid","display_name":"plasma uric acid","score":0.984000027179718},{"id":"https://openalex.org/keywords/high-fructose-corn-syrup","display_name":"high fructose corn syrup","score":0.9190000295639038},{"id":"https://openalex.org/keywords/glucose","display_name":"glucose","score":0.4569999873638153},{"id":"https://openalex.org/keywords/sucrose","display_name":"sucrose","score":0.7519999742507935},{"id":"https://openalex.org/keywords/gout-risk","display_name":"gout risk","score":0.5680000185966492},{"id":"https://openalex.org/keywords/hyperuricemia","display_name":"hyperuricemia","score":0.6079999804496765},{"id":"https://openalex.org/keywords/healthy-adults","display_name":"healthy adults","score":0.5260000228881836},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.5899999737739563},{"id":"https://openalex.org/keywords/dietary-fructose-intake","display_name":"dietary fructose intake","score":0.527999997138977},{"id":"https://openalex.org/keywords/sprites","display_name":"sprites","score":0.31700000166893005},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.5569999814033508},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.9010000228881836},{"id":"https://openalex.org/keywords/visceral-fat","display_name":"visceral fat","score":0.9070000052452087},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7390000224113464},{"id":"https://openalex.org/keywords/gout","display_name":"gout","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C2776970464","wikidata":"https://www.wikidata.org/wiki/Q122043","display_name":"Fructose","level":2,"score":0.7472436428070068},{"id":"https://openalex.org/C2777108408","wikidata":"https://www.wikidata.org/wiki/Q11002","display_name":"Sugar","level":2,"score":0.7001978158950806},{"id":"https://openalex.org/C2779881121","wikidata":"https://www.wikidata.org/wiki/Q105522","display_name":"Uric acid","level":2,"score":0.6967612504959106},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.6424729824066162},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5012094974517822},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3348746597766876},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24913671612739563}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:alma.64OTAGO_INST:11396468660001891","doi":null,"is_oa":true,"landing_page_url":"https://ourarchive.otago.ac.nz/esploro/outputs/graduate/Fructose-Intake-from-Sugar-Sweetened-Beverages-and/9926478451401891","pdf_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396468650001891/13397058740001891","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Masters Thesis"},{"id":"pmh:oai:ourarchive.otago.ac.nz:10523/6283","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10523/6283","pdf_url":"http://hdl.handle.net/10523/6283","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis or Dissertation"},{"id":"mag:2300769699","doi":null,"is_oa":false,"landing_page_url":"https://ourarchive.otago.ac.nz/bitstream/10523/6283/3/CarranEmma2016MDiet.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:alma.64OTAGO_INST:11396468660001891","doi":null,"is_oa":true,"landing_page_url":"https://ourarchive.otago.ac.nz/esploro/outputs/graduate/Fructose-Intake-from-Sugar-Sweetened-Beverages-and/9926478451401891","pdf_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396468650001891/13397058740001891","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Masters Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2300769699.pdf","grobid_xml":"https://content.openalex.org/works/W2300769699.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W158793992","https://openalex.org/W183300633","https://openalex.org/W1532812722","https://openalex.org/W1536645213","https://openalex.org/W1636607773","https://openalex.org/W1921920170","https://openalex.org/W1935669509","https://openalex.org/W1969346234","https://openalex.org/W1984960406","https://openalex.org/W1986434977","https://openalex.org/W1987339529","https://openalex.org/W1988249510","https://openalex.org/W1993083361","https://openalex.org/W2009684426","https://openalex.org/W2025372788","https://openalex.org/W2029745556","https://openalex.org/W2036956142","https://openalex.org/W2043105362","https://openalex.org/W2043947812","https://openalex.org/W2052212087","https://openalex.org/W2054723712","https://openalex.org/W2057077123","https://openalex.org/W2058232458","https://openalex.org/W2063161169","https://openalex.org/W2076784879","https://openalex.org/W2099789099","https://openalex.org/W2105476490","https://openalex.org/W2113894032","https://openalex.org/W2114856205","https://openalex.org/W2118783525","https://openalex.org/W2120545897","https://openalex.org/W2121431903","https://openalex.org/W2130234883","https://openalex.org/W2132895884","https://openalex.org/W2133462556","https://openalex.org/W2139136899","https://openalex.org/W2140699761","https://openalex.org/W2142415957","https://openalex.org/W2144653830","https://openalex.org/W2146966453","https://openalex.org/W2148658043","https://openalex.org/W2156789043","https://openalex.org/W2160182726","https://openalex.org/W2160399930","https://openalex.org/W2162309758","https://openalex.org/W2167400447","https://openalex.org/W2168068636","https://openalex.org/W2172103280","https://openalex.org/W2783591218"],"related_works":["https://openalex.org/W2472823754","https://openalex.org/W2791130309","https://openalex.org/W2909025119","https://openalex.org/W3164945637","https://openalex.org/W3172430604","https://openalex.org/W110601050","https://openalex.org/W2003488734","https://openalex.org/W4221017536","https://openalex.org/W2778796170","https://openalex.org/W162952067"],"abstract_inverted_index":{"Background:":[0],"Sucrose":[1],"intake,":[2],"half":[3],"of":[4,17,34,54,68,101,121,127,209,217,222,247,250,253,258,265,308,326],"which":[5,63,110],"is":[6,111],"fructose,":[7,259],"has":[8,28,40],"been":[9],"increasing":[10],"over":[11],"recent":[12],"decades.":[13],"Additionally,":[14],"the":[15,26,37,45,66,90,94,99,102,107,113,119,138,155,159,167,182,205,245,248,256,293,327,339,343,348,363,370,380,415,422,427],"introduction":[16],"high":[18],"fructose":[19,35,55,73,103,174,202,254,290,351,366,424],"corn":[20],"syrup":[21],"in":[22,25,36,44,106,137,194,296,338,360,391,400,414],"North":[23],"America":[24],"1970s":[27],"also":[29],"led":[30],"to":[31,57,65,75,154],"an":[32],"increase":[33],"diet.":[38],"Fructose":[39],"caused":[41],"much":[42],"debate":[43],"scientific":[46],"and":[47,60,83,175,189,231,234,255,285,347,350,365,369,372,383,426],"wider":[48],"community.":[49],"The":[50,213,289,312],"unregulated":[51],"metabolic":[52],"pathway":[53],"leads":[56],"uric":[58,134,239,269,280,298,318,329,393,402,418],"acid":[59,135,270,281,299,319,330,394,403,419],"fat":[61],"production,":[62],"contributes":[64],"burden":[67],"disease.":[69],"Studies":[70],"have":[71],"linked":[72],"consumption":[74],"obesity,":[76],"diabetes,":[77],"gout,":[78],"hypertension,":[79],"fatty":[80],"liver":[81],"disease":[82],"increased":[84],"visceral":[85],"fat.":[86],"Some":[87],"researchers":[88],"question":[89],"previous":[91],"research,":[92],"with":[93,204,334],"largest":[95,294],"concern":[96],"being":[97],"around":[98],"feasibility":[100],"dose":[104],"used":[105],"current":[108],"literature,":[109],"producing":[112],"pathological":[114],"change.":[115],"\\nObjective:":[116],"To":[117],"determine":[118],"effects":[120],"two":[122,164],"commonly":[123],"consumed":[124,170,185,306],"single-serve":[125],"amounts":[126],"a":[128,141,171,176,186,263,357],"sugar-sweetened":[129,160,274],"beverage":[130,161,193,275,352,376],"on":[131,267],"acute":[132],"plasma":[133,238,268,279,297,317,328,392,401,417],"concentration":[136,300,320],"body":[139],"within":[140],"healthy":[142],"New":[143],"Zealand":[144],"population.\\nDesign:":[145],"Randomised":[146],"crossover":[147],"control":[148,156,168,291,314,367,425],"trial\\nMethods:":[149],"Forty-two":[150],"participants":[151],"were":[152,199,226,235],"randomised":[153],"group":[157,169,184],"or":[158,261],"intervention.":[162],"Across":[163],"testing":[165],"days,":[166],"600":[172,177,190,206,373,384,430],"ml":[173,178,188,191,207,215,374,382,385,431],"glucose":[179,313,364,371],"beverage,":[180],"while":[181],"intervention":[183],"355":[187,214,381],"Sprite":[192,210,218,344,349,375,386,432],"random":[195],"order.":[196],"Control":[197],"beverages":[198,307,345],"matched":[200],"for":[201,237],"content":[203],"bottle":[208],"(26.7":[211],"g).":[212],"can":[216],"delivered":[219],"15.8":[220],"g":[221],"fructose.":[223],"Blood":[224],"samples":[225],"collected":[227],"at":[228,301],"baseline,":[229],"30":[230,284],"60":[232,286,302,322],"minutes":[233,287,303,323],"analysed":[236],"acid.":[240],"This":[241],"study":[242],"design":[243],"enabled":[244],"assessment":[246],"effect":[249],"different":[251],"doses":[252],"form":[257],"pure":[260,423],"as":[262,407],"component":[264],"sucrose":[266,428],"response.":[271],"\\nResults:":[272],"Both":[273,379],"volumes":[276],"significantly":[277,315],"raised":[278],"levels":[282],"after":[283,321],"(P<0.05).":[288],"produced":[292],"rise":[295,399],"across":[304],"all":[305],"26.34":[309],"\u03bcmol/L":[310],"(P=0.004).":[311],"decreased":[316],"(P=0.018).":[324],"IAUC":[325],"response":[331,341,404,420],"was":[332,356,405],"measured,":[333],"no":[335,412],"significant":[336,358,389],"difference":[337,359,413],"body\u2019s":[340,416],"between":[342,362,421],"(P=0.499)":[346],"(P=0.114).":[353],"However,":[354],"there":[355],"iAUC":[361],"(P=<0.001)":[368],"(P=0.015).":[377],"\\nConclusion:":[378],"exhibited":[387],"statistically":[388],"rises":[390],"concentration,":[395],"however,":[396],"this":[397],"transient":[398],"perceived":[406],"clinically":[408],"insignificant.":[409],"We":[410],"found":[411],"sweetened":[429],"beverage.":[433]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}
