{"id":"https://openalex.org/W2300634849","doi":"https://doi.org/10.1186/s13104-016-1895-8","title":"The best objective response of target lesions and the incidence of treatment-related hypertension are associated with the survival of patients with metastatic renal cell carcinoma treated with sunitinib: a Japanese retrospective study","display_name":"The best objective response of target lesions and the incidence of treatment-related hypertension are associated with the survival of patients with metastatic renal cell carcinoma treated with sunitinib: a Japanese retrospective study","publication_year":2016,"publication_date":"2016-02-09","ids":{"openalex":"https://openalex.org/W2300634849","doi":"https://doi.org/10.1186/s13104-016-1895-8","mag":"2300634849","pmid":"https://pubmed.ncbi.nlm.nih.gov/26861149","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4748467"},"language":"en","primary_location":{"id":"doi:10.1186/s13104-016-1895-8","doi":"https://doi.org/10.1186/s13104-016-1895-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13104-016-1895-8","pdf_url":"https://bmcresnotes.biomedcentral.com/track/pdf/10.1186/s13104-016-1895-8","source":{"id":"https://openalex.org/S100014455","display_name":"BMC Research Notes","issn_l":"1756-0500","issn":["1756-0500"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Research Notes","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcresnotes.biomedcentral.com/track/pdf/10.1186/s13104-016-1895-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050544002","display_name":"Makito Miyake","orcid":"https://orcid.org/0000-0001-9503-7356","observed_orcids":["https://orcid.org/0000-0001-9503-7356"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makito Miyake","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. makitomiyake@yahoo.co.jp","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. makitomiyake@yahoo.co.jp","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078824656","display_name":"Masaomi Kuwada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaomi Kuwada","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. masaomikuwada@gmail.com","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. masaomikuwada@gmail.com","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056075642","display_name":"Shunta Hori","orcid":"https://orcid.org/0000-0001-9514-9964","observed_orcids":["https://orcid.org/0000-0001-9514-9964"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunta Hori","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. horimaus@gmail.com","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. horimaus@gmail.com","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000306803","display_name":"Yosuke Morizawa","orcid":"https://orcid.org/0000-0001-7142-5901","observed_orcids":["https://orcid.org/0000-0001-7142-5901"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yosuke Morizawa","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. tigers.yosuke@gmail.com","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. tigers.yosuke@gmail.com","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035555896","display_name":"Yoshihiro Tatsumi","orcid":"https://orcid.org/0000-0002-0860-6889","observed_orcids":["https://orcid.org/0000-0002-0860-6889"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiro Tatsumi","raw_affiliation_strings":["Department of Pathology, Nara Medical University, Nara, Japan. takuro.birds.nest@gmail.com","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. takuro.birds.nest@gmail.com","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Nara Medical University, Nara, Japan. takuro.birds.nest@gmail.com","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. takuro.birds.nest@gmail.com","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039725947","display_name":"Satoshi Anai","orcid":"https://orcid.org/0000-0002-3552-1311","observed_orcids":["https://orcid.org/0000-0002-3552-1311"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Anai","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. sanai@naramed-u.ac.jp","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. sanai@naramed-u.ac.jp","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018716870","display_name":"Yukinari Hosokawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukinari Hosokawa","raw_affiliation_strings":["Department of Urology, Tane General Hospital, Osaka, Japan. yukinari46@nyc.odn.ne.jp","Department of Urology, Tane General Hospital, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Tane General Hospital, Osaka, Japan. yukinari46@nyc.odn.ne.jp","institution_ids":["https://openalex.org/I4210131591"]},{"raw_affiliation_string":"Department of Urology, Tane General Hospital, Osaka, Japan","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090942576","display_name":"Yoshiki Hayashi","orcid":"https://orcid.org/0000-0002-8966-8730","observed_orcids":["https://orcid.org/0000-0002-8966-8730"]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiki Hayashi","raw_affiliation_strings":["Department of Urology, Tane General Hospital, Osaka, Japan. uro@tane.or.jp","Department of Urology, Tane General Hospital, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Tane General Hospital, Osaka, Japan. uro@tane.or.jp","institution_ids":["https://openalex.org/I4210131591"]},{"raw_affiliation_string":"Department of Urology, Tane General Hospital, Osaka, Japan","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064296815","display_name":"Atsushi Tomioka","orcid":"https://orcid.org/0000-0001-7008-1502","observed_orcids":["https://orcid.org/0000-0001-7008-1502"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Atsushi Tomioka","raw_affiliation_strings":["Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan. tomioka515@yahoo.co.jp","Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan. tomioka515@yahoo.co.jp","institution_ids":[]},{"raw_affiliation_string":"Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083230671","display_name":"Takeshi Otani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takeshi Otani","raw_affiliation_strings":["Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan. t-otani@mch.miekosei.or.jp","Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan. t-otani@mch.miekosei.or.jp","institution_ids":[]},{"raw_affiliation_string":"Department of Urology, Matsuzaka Chuo General Hospital, Mie, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kenji Otsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405254308","display_name":"Yamato Takada Municipal Hospital","ror":"https://ror.org/01nnzt520","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405254308"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Otsuka","raw_affiliation_strings":["Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan. maccoi41@yahoo.co.jp","Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan. maccoi41@yahoo.co.jp","institution_ids":["https://openalex.org/I4405254308"]},{"raw_affiliation_string":"Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan","institution_ids":["https://openalex.org/I4405254308"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113592184","display_name":"Yoshinori Nakagawa","orcid":"https://orcid.org/0009-0006-6126-6250","observed_orcids":["https://orcid.org/0009-0006-6126-6250"]},"institutions":[{"id":"https://openalex.org/I4405254308","display_name":"Yamato Takada Municipal Hospital","ror":"https://ror.org/01nnzt520","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405254308"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshinori Nakagawa","raw_affiliation_strings":["Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan. nakagawa@ym-hp.yamatotakada.nara.jp","Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan. nakagawa@ym-hp.yamatotakada.nara.jp","institution_ids":["https://openalex.org/I4405254308"]},{"raw_affiliation_string":"Department of Urology, Yamato Takada Municipal Hospital, Nara, Japan","institution_ids":["https://openalex.org/I4405254308"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056692031","display_name":"Yasushi Nakai","orcid":"https://orcid.org/0000-0002-7579-0372","observed_orcids":["https://orcid.org/0000-0002-7579-0372","https://orcid.org/0000-0002-3255-4839"]},"institutions":[{"id":"https://openalex.org/I4387153019","display_name":"Nara Prefecture General Medical Center","ror":"https://ror.org/00bhf8j88","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387153019","https://openalex.org/I4405284808"]},{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Nakai","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. unnkoderu@hotmail.com","Department of Urology, Nara Prefecture General Medical Center, Nara, Japan. unnkoderu@hotmail.com","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. unnkoderu@hotmail.com","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Prefecture General Medical Center, Nara, Japan. unnkoderu@hotmail.com","institution_ids":["https://openalex.org/I4387153019"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083149613","display_name":"Shoji Samma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153019","display_name":"Nara Prefecture General Medical Center","ror":"https://ror.org/00bhf8j88","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387153019","https://openalex.org/I4405284808"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoji Samma","raw_affiliation_strings":["Department of Urology, Nara Prefecture General Medical Center, Nara, Japan. urodept@m3.kcn.ne.jp","Department of Urology, Nara Prefecture General Medical Center, Nara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Prefecture General Medical Center, Nara, Japan. urodept@m3.kcn.ne.jp","institution_ids":["https://openalex.org/I4387153019"]},{"raw_affiliation_string":"Department of Urology, Nara Prefecture General Medical Center, Nara, Japan","institution_ids":["https://openalex.org/I4387153019"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071529858","display_name":"Nobumichi Tanaka","orcid":"https://orcid.org/0000-0001-9242-7877","observed_orcids":["https://orcid.org/0000-0001-9242-7877"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobumichi Tanaka","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. sendo@naramed-u.ac.jp","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. sendo@naramed-u.ac.jp","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017624165","display_name":"Kiyohide Fujimoto","orcid":"https://orcid.org/0000-0003-1507-2464","observed_orcids":["https://orcid.org/0000-0003-1507-2464"]},"institutions":[{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kiyohide Fujimoto","raw_affiliation_strings":["Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. kiyokun@naramed-u.ac.jp","Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan. kiyokun@naramed-u.ac.jp","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Urology, Nara Medical University, 840 Shijo-cho, Nara, 634-8522, Japan","institution_ids":["https://openalex.org/I64926303"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5017624165"],"corresponding_institution_ids":["https://openalex.org/I64926303"],"apc_list":{"value":1690,"currency":"USD","value_usd":1690},"apc_paid":{"value":1690,"currency":"USD","value_usd":1690},"fwci":1.1741,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.79465489,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"9","issue":"1","first_page":"79","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metastatic-renal-cell-carcinoma","display_name":"metastatic renal cell carcinoma","score":0.9660000205039978},{"id":"https://openalex.org/keywords/sunitinib","display_name":"sunitinib","score":1.0},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.6869999766349792},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.8709999918937683},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":1.0},{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.8270000219345093},{"id":"https://openalex.org/keywords/response-evaluation-criteria-in-solid-tumors","display_name":"response evaluation criteria in solid tumors","score":0.800000011920929},{"id":"https://openalex.org/keywords/tyrosine-kinase-inhibitor-adverse-effects","display_name":"tyrosine kinase inhibitor adverse effects","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C2779490328","wikidata":"https://www.wikidata.org/wiki/Q417542","display_name":"Sunitinib","level":3,"score":0.9167026281356812},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9149167537689209},{"id":"https://openalex.org/C2777472916","wikidata":"https://www.wikidata.org/wiki/Q1164529","display_name":"Renal cell carcinoma","level":2,"score":0.7671289443969727},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.7388224005699158},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6633410453796387},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5371615886688232},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5349280834197998},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077210","descriptor_name":"Sunitinib","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002292","descriptor_name":"Carcinoma, Renal Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002292","descriptor_name":"Carcinoma, Renal Cell","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":true},{"descriptor_ui":"D003710","descriptor_name":"Demography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007211","descriptor_name":"Indoles","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D007211","descriptor_name":"Indoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011758","descriptor_name":"Pyrroles","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D011758","descriptor_name":"Pyrroles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1186/s13104-016-1895-8","doi":"https://doi.org/10.1186/s13104-016-1895-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13104-016-1895-8","pdf_url":"https://bmcresnotes.biomedcentral.com/track/pdf/10.1186/s13104-016-1895-8","source":{"id":"https://openalex.org/S100014455","display_name":"BMC Research Notes","issn_l":"1756-0500","issn":["1756-0500"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Research Notes","raw_type":"journal-article"},{"id":"pmid:26861149","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26861149","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC research notes","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4748467","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4748467/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Res Notes","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13104-016-1895-8","doi":"https://doi.org/10.1186/s13104-016-1895-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13104-016-1895-8","pdf_url":"https://bmcresnotes.biomedcentral.com/track/pdf/10.1186/s13104-016-1895-8","source":{"id":"https://openalex.org/S100014455","display_name":"BMC Research Notes","issn_l":"1756-0500","issn":["1756-0500"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Research Notes","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320323434","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2300634849.pdf","grobid_xml":"https://content.openalex.org/works/W2300634849.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W656006518","https://openalex.org/W1711115929","https://openalex.org/W1973663909","https://openalex.org/W1989821242","https://openalex.org/W1998005755","https://openalex.org/W2003621633","https://openalex.org/W2019607817","https://openalex.org/W2036515537","https://openalex.org/W2049098629","https://openalex.org/W2053874226","https://openalex.org/W2059927424","https://openalex.org/W2072006879","https://openalex.org/W2099088585","https://openalex.org/W2099752220","https://openalex.org/W2102942754","https://openalex.org/W2106591331","https://openalex.org/W2106622364","https://openalex.org/W2107567753","https://openalex.org/W2113322173","https://openalex.org/W2123534406","https://openalex.org/W2141849536","https://openalex.org/W2143782771","https://openalex.org/W2145473922","https://openalex.org/W2146147508","https://openalex.org/W2155295247","https://openalex.org/W2156408558","https://openalex.org/W2589250791","https://openalex.org/W2602945533","https://openalex.org/W2991874119"],"related_works":["https://openalex.org/W2119404465","https://openalex.org/W2036515537","https://openalex.org/W2588943458","https://openalex.org/W2123684576","https://openalex.org/W1490675613","https://openalex.org/W7098802371","https://openalex.org/W2940979887","https://openalex.org/W2044425343","https://openalex.org/W2587371894","https://openalex.org/W2590403908"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,107,134],"aim":[2],"of":[3,12,17,34,94,136,195,197,234,254],"this":[4],"study":[5],"is":[6],"to":[7,40,102,221],"investigate":[8],"the":[9,13,35,41,56,157,171,198,222,230,252],"prognostic":[10,104,239],"relevance":[11],"best":[14,36,108,231],"objective":[15,37,109,145,232],"response":[16,38,71,74,110,233],"metastatic":[18,27],"target":[19,235],"lesions":[20,236],"during":[21],"sunitinib":[22,249],"treatment":[23,85],"in":[24,45,50,113,119,124,130,156,248],"patients":[25],"with":[26,142,259],"renal":[28],"cell":[29],"carcinoma.":[30],"METHODS:":[31],"Radiographic":[32],"analysis":[33,188],"according":[39],"Response":[42],"Evaluation":[43],"Criteria":[44],"Solid":[46],"Tumors":[47],"was":[48,111,140,149,176,237,257],"assessed":[49],"50":[51],"patients.":[52],"Clinicopathological":[53],"characteristics":[54],"including":[55],"Heng":[57],"risk":[58,194],"classification":[59],"and":[60,82,89,97,128,138,153,161,180,201,213,245],"sunitinib-related":[61],"adverse":[62],"reactions":[63],"were":[64,100,204],"compared":[65,220],"among":[66],"four":[67],"patient":[68],"subgroups":[69],"[complete":[70],"or":[72],"partial":[73],"(CR/PR),":[75],"stable":[76],"disease":[77,80],"(SD),":[78],"progressive":[79],"(PD),":[81],"those":[83],"without":[84],"evaluation":[86],"(NE)].":[87],"Kaplan-Meier":[88],"Cox":[90],"proportional":[91],"regression":[92],"analyses":[93],"progression-free":[95,243,262],"survival":[96,99,148,175,244,247],"overall":[98,174,246],"performed":[101],"identify":[103],"variables.":[105],"RESULTS:":[106],"CR/PR":[112,223],"12":[114],"(24":[115],"%)":[116],"patients,":[117],"SD":[118],"22":[120],"(44":[121],"%),":[122,127],"PD":[123],"6":[125],"(12":[126],"NE":[129,162,202],"10":[131],"(20":[132],"%).":[133],"incidence":[135,253],"hypertension":[137,256],"hypothyroidism":[139],"associated":[141,258],"a":[143,238,260],"better":[144],"response.":[146],"Progression-free":[147],"15.0,":[150],"9.2,":[151],"6.8,":[152],"2.2":[154],"months":[155],"CR/PR,":[158],"SD,":[159,199],"PD,":[160,200],"groups,":[163],"respectively":[164,183],"(P":[165,184,206,210,215],"=":[166,185,207,211,216],"0.0004,":[167],"log-rank":[168],"test),":[169],"while":[170],"corresponding":[172],"median":[173],"59.7,":[177],"24.2,":[178],"17.1,":[179],"18.1":[181],"months,":[182],"0.007).":[186],"Multivariate":[187],"revealed":[189],"that":[190,229],"hazard":[191],"ratios":[192],"for":[193,241],"death":[196],"groups":[203],"4.51":[205],"0.06),":[208],"7.93":[209],"0.02),":[212],"4.88":[214],"0.04),":[217],"respectively,":[218],"as":[219],"group.":[224],"CONCLUSIONS:":[225],"Our":[226],"findings":[227],"suggested":[228],"marker":[240],"both":[242],"treatment.":[250],"Furthermore,":[251],"sunitinib-induced":[255],"longer":[261],"survival.":[263]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}