{"id":"https://openalex.org/W2299861382","doi":"https://doi.org/10.1016/j.canlet.2016.03.019","title":"N-acetylgalactosamine glycans function in cancer cell adhesion to endothelial cells: A role for truncated O-glycans in metastatic mechanisms","display_name":"N-acetylgalactosamine glycans function in cancer cell adhesion to endothelial cells: A role for truncated O-glycans in metastatic mechanisms","publication_year":2016,"publication_date":"2016-03-16","ids":{"openalex":"https://openalex.org/W2299861382","doi":"https://doi.org/10.1016/j.canlet.2016.03.019","mag":"2299861382","pmid":"https://pubmed.ncbi.nlm.nih.gov/26994652"},"language":"en","primary_location":{"id":"doi:10.1016/j.canlet.2016.03.019","doi":"https://doi.org/10.1016/j.canlet.2016.03.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.canlet.2016.03.019","pdf_url":null,"source":{"id":"https://openalex.org/S106234763","display_name":"Cancer Letters","issn_l":"0304-3835","issn":["0304-3835","1872-7980"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://radar.brookes.ac.uk/radar/items/2a586e9f-f5d7-477e-a155-ff7579d93f9e/1/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001325912","display_name":"Deepashree Bapu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124261462","display_name":"Oxford Brookes University","ror":"https://ror.org/04v2twj65","country_code":"GB","type":"education","lineage":["https://openalex.org/I124261462"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Deepashree Bapu","raw_affiliation_strings":["Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK","institution_ids":["https://openalex.org/I124261462"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049055944","display_name":"John Runions","orcid":"https://orcid.org/0000-0001-6614-1226","observed_orcids":["https://orcid.org/0000-0001-6614-1226"]},"institutions":[{"id":"https://openalex.org/I124261462","display_name":"Oxford Brookes University","ror":"https://ror.org/04v2twj65","country_code":"GB","type":"education","lineage":["https://openalex.org/I124261462"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Runions","raw_affiliation_strings":["Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK","institution_ids":["https://openalex.org/I124261462"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110161247","display_name":"Munira A Kadhim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124261462","display_name":"Oxford Brookes University","ror":"https://ror.org/04v2twj65","country_code":"GB","type":"education","lineage":["https://openalex.org/I124261462"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Munira Kadhim","raw_affiliation_strings":["Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK","institution_ids":["https://openalex.org/I124261462"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029076639","display_name":"Susan Ann Brooks","orcid":"https://orcid.org/0000-0002-7908-7078","observed_orcids":["https://orcid.org/0000-0002-7908-7078"]},"institutions":[{"id":"https://openalex.org/I124261462","display_name":"Oxford Brookes University","ror":"https://ror.org/04v2twj65","country_code":"GB","type":"education","lineage":["https://openalex.org/I124261462"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Susan Ann Brooks","raw_affiliation_strings":["Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK. Electronic address: sbrooks@brookes.ac.uk","Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK. Electronic address: sbrooks@brookes.ac.uk","institution_ids":["https://openalex.org/I124261462"]},{"raw_affiliation_string":"Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3\u20090BP, UK","institution_ids":["https://openalex.org/I124261462"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5029076639"],"corresponding_institution_ids":["https://openalex.org/I124261462"],"apc_list":{"value":4960,"currency":"USD","value_usd":4960},"apc_paid":null,"fwci":2.1767,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.874706,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"375","issue":"2","first_page":"367","last_page":"374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tn-antigen","display_name":"Tn antigen","score":0.8100000023841858},{"id":"https://openalex.org/keywords/tumor-cell-adhesion","display_name":"tumor cell adhesion","score":0.9010000228881836},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.9169999957084656},{"id":"https://openalex.org/keywords/breast-cancer-metastasis","display_name":"breast cancer metastasis","score":0.8040000200271606},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.7829999923706055},{"id":"https://openalex.org/keywords/zr-75-1-cells","display_name":"ZR-75-1 cells","score":0.8259999752044678},{"id":"https://openalex.org/keywords/bt474-cells","display_name":"BT474 cells","score":0.9729999899864197},{"id":"https://openalex.org/keywords/cell-motility","display_name":"cell motility","score":0.4970000088214874},{"id":"https://openalex.org/keywords/cell-morphology","display_name":"cell morphology","score":0.6069999933242798},{"id":"https://openalex.org/keywords/colony-formation","display_name":"colony formation","score":0.5630000233650208}],"concepts":[{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.5719960927963257},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.5539386868476868},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5526790618896484},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.5210021138191223},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4342527687549591},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4024515151977539},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40068110823631287},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37452617287635803},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3693930506706238},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3488333821296692},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.31938523054122925},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.11134162545204163},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000116","descriptor_name":"Acetylgalactosamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015295","descriptor_name":"Antigens, Tumor-Associated, Carbohydrate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061986","descriptor_name":"MCF-7 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.canlet.2016.03.019","doi":"https://doi.org/10.1016/j.canlet.2016.03.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.canlet.2016.03.019","pdf_url":null,"source":{"id":"https://openalex.org/S106234763","display_name":"Cancer Letters","issn_l":"0304-3835","issn":["0304-3835","1872-7980"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Letters","raw_type":"journal-article"},{"id":"pmid:26994652","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26994652","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer letters","raw_type":"Journal Article"},{"id":"pmh:tle:2a586e9f-f5d7-477e-a155-ff7579d93f9e:afee126f-04b2-41a9-a6dd-b29b7c6c20ab:1","doi":null,"is_oa":true,"landing_page_url":"https://radar.brookes.ac.uk/radar/items/2a586e9f-f5d7-477e-a155-ff7579d93f9e/1/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400541","display_name":"Radar (Oxford Brookes University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124261462","host_organization_name":"Oxford Brookes University","host_organization_lineage":["https://openalex.org/I124261462"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"N-acetylgalactosamine glycans function in cancer cell adhesion to endothelial cells: a role for truncated O-glycans in metastatic mechanisms","raw_type":"journal article"},{"id":"pmh:tle:2a586e9f-f5d7-477e-a155-ff7579d93f9e:b4ef9587-4603-18f8-a471-bb20511f0ad9:1","doi":null,"is_oa":true,"landing_page_url":"https://radar.brookes.ac.uk/radar/items/2a586e9f-f5d7-477e-a155-ff7579d93f9e/1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400541","display_name":"Radar (Oxford Brookes University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124261462","host_organization_name":"Oxford Brookes University","host_organization_lineage":["https://openalex.org/I124261462"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Letters","raw_type":"Journal Article/Review"}],"best_oa_location":{"id":"pmh:tle:2a586e9f-f5d7-477e-a155-ff7579d93f9e:afee126f-04b2-41a9-a6dd-b29b7c6c20ab:1","doi":null,"is_oa":true,"landing_page_url":"https://radar.brookes.ac.uk/radar/items/2a586e9f-f5d7-477e-a155-ff7579d93f9e/1/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400541","display_name":"Radar (Oxford Brookes University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124261462","host_organization_name":"Oxford Brookes University","host_organization_lineage":["https://openalex.org/I124261462"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"N-acetylgalactosamine glycans function in cancer cell adhesion to endothelial cells: a role for truncated O-glycans in metastatic mechanisms","raw_type":"journal article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W11607516","https://openalex.org/W54149052","https://openalex.org/W115828403","https://openalex.org/W140582050","https://openalex.org/W241130063","https://openalex.org/W245195134","https://openalex.org/W1536370890","https://openalex.org/W1545127830","https://openalex.org/W1586710584","https://openalex.org/W1886493391","https://openalex.org/W1901601415","https://openalex.org/W1947796218","https://openalex.org/W1967993480","https://openalex.org/W1968985594","https://openalex.org/W1969414215","https://openalex.org/W1974164558","https://openalex.org/W1975805177","https://openalex.org/W1978628694","https://openalex.org/W1987640672","https://openalex.org/W1988138737","https://openalex.org/W1989244889","https://openalex.org/W1993657026","https://openalex.org/W1993869485","https://openalex.org/W1999137197","https://openalex.org/W2000697153","https://openalex.org/W2006611326","https://openalex.org/W2010381820","https://openalex.org/W2014846224","https://openalex.org/W2017107299","https://openalex.org/W2027226026","https://openalex.org/W2027401382","https://openalex.org/W2032371793","https://openalex.org/W2036254154","https://openalex.org/W2036693324","https://openalex.org/W2039093241","https://openalex.org/W2046043897","https://openalex.org/W2051622472","https://openalex.org/W2056634642","https://openalex.org/W2057113428","https://openalex.org/W2058194911","https://openalex.org/W2065716393","https://openalex.org/W2069261679","https://openalex.org/W2075915597","https://openalex.org/W2079484266","https://openalex.org/W2081507143","https://openalex.org/W2082290238","https://openalex.org/W2084529788","https://openalex.org/W2089142394","https://openalex.org/W2099195012","https://openalex.org/W2100124039","https://openalex.org/W2102276910","https://openalex.org/W2102865930","https://openalex.org/W2103885797","https://openalex.org/W2113357723","https://openalex.org/W2117692326","https://openalex.org/W2119311154","https://openalex.org/W2120590911","https://openalex.org/W2129645836","https://openalex.org/W2129940081","https://openalex.org/W2132278969","https://openalex.org/W2134294354","https://openalex.org/W2143008979","https://openalex.org/W2159642798","https://openalex.org/W2163942900","https://openalex.org/W2292359171","https://openalex.org/W2412068318","https://openalex.org/W2412883611","https://openalex.org/W2416651232","https://openalex.org/W4235962238"],"related_works":["https://openalex.org/W2074122092","https://openalex.org/W7038448158","https://openalex.org/W4381664397","https://openalex.org/W2954438070","https://openalex.org/W6907742049","https://openalex.org/W2039093241","https://openalex.org/W2068691191","https://openalex.org/W7165766911","https://openalex.org/W2120191608","https://openalex.org/W245195134"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
