{"id":"https://openalex.org/W2299004124","doi":"https://doi.org/10.1371/journal.pgen.1005907","title":"A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis","display_name":"A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis","publication_year":2016,"publication_date":"2016-03-15","ids":{"openalex":"https://openalex.org/W2299004124","doi":"https://doi.org/10.1371/journal.pgen.1005907","mag":"2299004124","pmid":"https://pubmed.ncbi.nlm.nih.gov/26977770","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4792503"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pgen.1005907","doi":"https://doi.org/10.1371/journal.pgen.1005907","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1005907","pdf_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005907&type=printable","source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Genetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005907&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023752774","display_name":"Christina Spilker","orcid":"https://orcid.org/0000-0002-7996-7673","observed_orcids":["https://orcid.org/0000-0002-7996-7673"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christina Spilker","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072477218","display_name":"Sven Nullmeier","orcid":"https://orcid.org/0000-0002-2162-116X","observed_orcids":["https://orcid.org/0000-0002-2162-116X"]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sven Nullmeier","raw_affiliation_strings":["Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061980180","display_name":"Katarzyna M. Grochowska","orcid":"https://orcid.org/0000-0001-8298-176X","observed_orcids":["https://orcid.org/0000-0001-8298-176X"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katarzyna M. Grochowska","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076328328","display_name":"Anne Schumacher","orcid":"https://orcid.org/0000-0002-6427-3724","observed_orcids":["https://orcid.org/0000-0002-6427-3724"]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anne Schumacher","raw_affiliation_strings":["Department of Experimental Obstetrics and Gynaecology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Obstetrics and Gynaecology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024835483","display_name":"Ioana Butnaru","orcid":"https://orcid.org/0000-0002-8011-9188","observed_orcids":["https://orcid.org/0000-0002-8011-9188"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ioana Butnaru","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051895428","display_name":"Tamar Macharadze","orcid":"https://orcid.org/0009-0008-1635-3931","observed_orcids":["https://orcid.org/0009-0008-1635-3931"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tamar Macharadze","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041885757","display_name":"Guilherme M. Gomes","orcid":"https://orcid.org/0000-0001-8566-4284","observed_orcids":["https://orcid.org/0000-0001-8566-4284"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Guilherme M. Gomes","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085055673","display_name":"PingAn Yuanxiang","orcid":"https://orcid.org/0000-0002-3746-3282","observed_orcids":["https://orcid.org/0000-0002-3746-3282"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"PingAn Yuanxiang","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017314192","display_name":"Gonca Bayraktar","orcid":"https://orcid.org/0000-0001-5476-4346","observed_orcids":["https://orcid.org/0000-0001-5476-4346"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gonca Bayraktar","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044894928","display_name":"Carolin Rodenstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Carolin Rodenstein","raw_affiliation_strings":["Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036261156","display_name":"Carolin Geiseler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Carolin Geiseler","raw_affiliation_strings":["Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022865878","display_name":"Angela Kolodziej","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Angela Kolodziej","raw_affiliation_strings":["Department of Systems Physiology of Learning, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems Physiology of Learning, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025827079","display_name":"Jeffrey Lopez\u2010Rojas","orcid":"https://orcid.org/0000-0001-9648-4051","observed_orcids":["https://orcid.org/0000-0001-9648-4051"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jeffrey Lopez-Rojas","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056781669","display_name":"Dirk Montag","orcid":"https://orcid.org/0000-0002-4964-1330","observed_orcids":["https://orcid.org/0000-0002-4964-1330"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dirk Montag","raw_affiliation_strings":["Special Laboratory Neurogenetics, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Special Laboratory Neurogenetics, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083420168","display_name":"Frank Angenstein","orcid":"https://orcid.org/0000-0003-1157-714X","observed_orcids":["https://orcid.org/0000-0003-1157-714X"]},"institutions":[{"id":"https://openalex.org/I2801533059","display_name":"German Center for Neurodegenerative Diseases","ror":"https://ror.org/043j0f473","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801533059","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Frank Angenstein","raw_affiliation_strings":["Functional Neuroimaging Group, Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen (DZNE), and Special Laboratory for Noninvasive Brain Imaging, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Functional Neuroimaging Group, Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen (DZNE), and Special Laboratory for Noninvasive Brain Imaging, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I2801533059","https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050064459","display_name":"Julia B\u00e4r","orcid":"https://orcid.org/0000-0002-0954-2776","observed_orcids":["https://orcid.org/0000-0002-0954-2776"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julia B\u00e4r","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Emmy-Noether Group 'Neuronal Protein Transport', Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]},{"raw_affiliation_string":"University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Emmy-Noether Group 'Neuronal Protein Transport', Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063976131","display_name":"Wolfgang D\u2019Hanis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wolfgang D\u2019Hanis","raw_affiliation_strings":["Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017751276","display_name":"Thomas Roskoden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Roskoden","raw_affiliation_strings":["Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075598160","display_name":"Marina Mikhaylova","orcid":"https://orcid.org/0000-0001-7646-1346","observed_orcids":["https://orcid.org/0000-0001-7646-1346"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marina Mikhaylova","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Emmy-Noether Group 'Neuronal Protein Transport', Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]},{"raw_affiliation_string":"University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Emmy-Noether Group 'Neuronal Protein Transport', Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089046528","display_name":"Eike Budinger","orcid":"https://orcid.org/0000-0003-2420-8159","observed_orcids":["https://orcid.org/0000-0003-2420-8159"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Eike Budinger","raw_affiliation_strings":["Department of Systems Physiology of Learning, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems Physiology of Learning, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087402600","display_name":"Frank W. Ohl","orcid":"https://orcid.org/0000-0001-8260-9423","observed_orcids":["https://orcid.org/0000-0001-8260-9423"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Frank W. Ohl","raw_affiliation_strings":["Department of Systems Physiology of Learning, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems Physiology of Learning, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067258427","display_name":"Oliver Stork","orcid":"https://orcid.org/0000-0003-4285-7507","observed_orcids":["https://orcid.org/0000-0003-4285-7507"]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oliver Stork","raw_affiliation_strings":["Institute of Biology, Otto von Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biology, Otto von Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057696929","display_name":"Ana Claudia Zenclussen","orcid":"https://orcid.org/0000-0003-3544-4552","observed_orcids":["https://orcid.org/0000-0003-3544-4552"]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ana C. Zenclussen","raw_affiliation_strings":["Department of Experimental Obstetrics and Gynaecology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Obstetrics and Gynaecology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047060848","display_name":"Anna Karpova","orcid":"https://orcid.org/0000-0001-7423-4764","observed_orcids":["https://orcid.org/0000-0001-7423-4764"]},"institutions":[{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anna Karpova","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005907406","display_name":"Herbert Schwegler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Herbert Schwegler","raw_affiliation_strings":["Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087488820","display_name":"Michael R. Kreutz","orcid":"https://orcid.org/0000-0003-0575-6950","observed_orcids":["https://orcid.org/0000-0003-0575-6950"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I96578850","display_name":"Leibniz Institute for Neurobiology","ror":"https://ror.org/01zwmgk08","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I96578850"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Michael R. Kreutz","raw_affiliation_strings":["Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Leibniz Group 'Dendritic Organelles and Synaptic Function', Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany","institution_ids":["https://openalex.org/I96578850"]},{"raw_affiliation_string":"University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Leibniz Group 'Dendritic Organelles and Synaptic Function', Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5087488820"],"corresponding_institution_ids":["https://openalex.org/I4210108711","https://openalex.org/I96578850"],"apc_list":{"value":3043,"currency":"USD","value_usd":3043},"apc_paid":{"value":2462,"currency":"EUR","value_usd":2655},"fwci":2.1527,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.86246075,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"3","first_page":"e1005907","last_page":"e1005907"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.7651000022888184,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.7651000022888184,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.08169999718666077,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.06970000267028809,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jacob","display_name":"Jacob","score":0.6140000224113464},{"id":"https://openalex.org/keywords/dendritogenesis","display_name":"dendritogenesis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/bdnf-signaling","display_name":"BDNF signaling","score":0.9810000061988831},{"id":"https://openalex.org/keywords/creb-phosphorylation","display_name":"CREB phosphorylation","score":0.9229999780654907},{"id":"https://openalex.org/keywords/nmda-receptor-signaling","display_name":"NMDA receptor signaling","score":0.8489999771118164},{"id":"https://openalex.org/keywords/kallmann-syndrome","display_name":"Kallmann syndrome","score":0.777999997138977},{"id":"https://openalex.org/keywords/hippocampal-long-term-potentiation","display_name":"hippocampal long-term potentiation","score":0.8029999732971191},{"id":"https://openalex.org/keywords/hippocampus-dependent-learning","display_name":"hippocampus-dependent learning","score":0.9390000104904175},{"id":"https://openalex.org/keywords/pyramidal-neurons","display_name":"pyramidal neurons","score":0.6650000214576721},{"id":"https://openalex.org/keywords/nuclear-translocation","display_name":"nuclear translocation","score":0.5210000276565552},{"id":"https://openalex.org/keywords/synaptogenesis","display_name":"synaptogenesis","score":0.5849999785423279}],"concepts":[{"id":"https://openalex.org/C1629964","wikidata":"https://www.wikidata.org/wiki/Q106950729","display_name":"CREB","level":4,"score":0.8645471334457397},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6623781323432922},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6359297037124634},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6337832808494568},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6336336135864258},{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.5391784906387329},{"id":"https://openalex.org/C2778790584","wikidata":"https://www.wikidata.org/wiki/Q123045","display_name":"Brain-derived neurotrophic factor","level":4,"score":0.5192394256591797},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.4873519837856293},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.4760817587375641},{"id":"https://openalex.org/C2776603820","wikidata":"https://www.wikidata.org/wiki/Q906517","display_name":"CREB-binding protein","level":5,"score":0.42292121052742004},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.42268311977386475},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.403219610452652},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.3409777283668518},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.16661062836647034},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15063410997390747},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11841884255409241},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0795152485370636}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007987","descriptor_name":"Gonadotropin-Releasing Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017362","descriptor_name":"Cyclic AMP Response Element-Binding Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pgen.1005907","doi":"https://doi.org/10.1371/journal.pgen.1005907","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1005907","pdf_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005907&type=printable","source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Genetics","raw_type":"journal-article"},{"id":"pmid:26977770","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26977770","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS genetics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4792503","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4792503/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Genet","raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/3962877","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/A_i_Jacob_Nsmf_i_Gene_Knockout_Results_in_Hippocampal_Dysplasia_and_Impaired_BDNF_Signaling_in_Dendritogenesis/3962877","pdf_url":"https://figshare.com/articles/dataset/A_i_Jacob_Nsmf_i_Gene_Knockout_Results_in_Hippocampal_Dysplasia_and_Impaired_BDNF_Signaling_in_Dendritogenesis/3962877","source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:frl.publisso.de:frl:6404295","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4792503","pdf_url":null,"source":{"id":"https://openalex.org/S4306402606","display_name":"Informationszentrum Lebenswissenschaften (ZB MED)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210112663","host_organization_name":"ZB MED - Information Centre for Life Sciences","host_organization_lineage":["https://openalex.org/I4210112663"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, 12(3): e1005907","raw_type":"Zeitschriftenartikel"},{"id":"pmh:oai:doaj.org/article:be102f6df7474cccbf12c201592fe231","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/be102f6df7474cccbf12c201592fe231","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, Vol 12, Iss 3, p e1005907 (2016)","raw_type":"article"},{"id":"pmh:oai:pub.dzne.de:138474","doi":null,"is_oa":true,"landing_page_url":"https://pub.dzne.de/record/138474","pdf_url":null,"source":{"id":"https://openalex.org/S7407051172","display_name":"DZNE Pub","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801533059","host_organization_name":"German Center for Neurodegenerative Diseases","host_organization_lineage":["https://openalex.org/I2801533059"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics 12(3), e1005907 (2016). doi:10.1371/journal.pgen.1005907","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1371/journal.pgen.1005907","doi":"https://doi.org/10.1371/journal.pgen.1005907","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1005907","pdf_url":"https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005907&type=printable","source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Genetics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1185992013","display_name":null,"funder_award_id":"Kr1879","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G1666510090","display_name":null,"funder_award_id":"TP B01","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3207356259","display_name":null,"funder_award_id":"2007\u20132013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3551634521","display_name":"NPlast - A neuroscience school that aims to preserve and restore neuroplasticity in brain disorders","funder_award_id":"289581","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3786385894","display_name":null,"funder_award_id":"Ml1923/1-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3877791864","display_name":null,"funder_award_id":"GRK 1167","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G393177772","display_name":null,"funder_award_id":"FP7 2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4760961572","display_name":null,"funder_award_id":"FP7/2007\u20132013","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4958738190","display_name":null,"funder_award_id":"SFB 779","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G510894165","display_name":null,"funder_award_id":"TPB05","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5640286300","display_name":null,"funder_award_id":"1923/1-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5702163051","display_name":null,"funder_award_id":"FP7/2007","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G861875927","display_name":null,"funder_award_id":"TP B08","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320308269","display_name":"Alexander von Humboldt-Stiftung","ror":"https://ror.org/012kf4317"},{"id":"https://openalex.org/F4320314158","display_name":"EU Joint Programme \u2013 Neurodegenerative Disease Research","ror":null},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"},{"id":"https://openalex.org/F4320323015","display_name":"Bundesministerium f\u00fcr Forschung und Technologie","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320334763","display_name":"Leibniz-Gemeinschaft","ror":"https://ror.org/01n6r0e97"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2299004124.pdf","grobid_xml":"https://content.openalex.org/works/W2299004124.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W1512733937","https://openalex.org/W1558650798","https://openalex.org/W1639233758","https://openalex.org/W1731473784","https://openalex.org/W1969854375","https://openalex.org/W1970044109","https://openalex.org/W1973883693","https://openalex.org/W1976698265","https://openalex.org/W1979586675","https://openalex.org/W1985044857","https://openalex.org/W1989976072","https://openalex.org/W1993376520","https://openalex.org/W1997874638","https://openalex.org/W1997956229","https://openalex.org/W1999517199","https://openalex.org/W2000700513","https://openalex.org/W2001354748","https://openalex.org/W2002358514","https://openalex.org/W2006433593","https://openalex.org/W2007393704","https://openalex.org/W2009216216","https://openalex.org/W2019374944","https://openalex.org/W2024684743","https://openalex.org/W2027443706","https://openalex.org/W2038122755","https://openalex.org/W2041555783","https://openalex.org/W2051108558","https://openalex.org/W2052223075","https://openalex.org/W2052322593","https://openalex.org/W2054662586","https://openalex.org/W2055633353","https://openalex.org/W2058281252","https://openalex.org/W2064111585","https://openalex.org/W2066828362","https://openalex.org/W2068053473","https://openalex.org/W2069316602","https://openalex.org/W2070058327","https://openalex.org/W2074698464","https://openalex.org/W2076090607","https://openalex.org/W2077512223","https://openalex.org/W2078231726","https://openalex.org/W2084973310","https://openalex.org/W2086528223","https://openalex.org/W2090305824","https://openalex.org/W2091820757","https://openalex.org/W2092549034","https://openalex.org/W2094212507","https://openalex.org/W2094270694","https://openalex.org/W2096568025","https://openalex.org/W2103531658","https://openalex.org/W2109242779","https://openalex.org/W2109309568","https://openalex.org/W2127360976","https://openalex.org/W2131472234","https://openalex.org/W2145305414","https://openalex.org/W2148691225","https://openalex.org/W2154727263","https://openalex.org/W2156831112","https://openalex.org/W2160792573","https://openalex.org/W2169307859","https://openalex.org/W2169478622"],"related_works":["https://openalex.org/W2546933188","https://openalex.org/W2394480589","https://openalex.org/W7063828498","https://openalex.org/W2091820757","https://openalex.org/W3158789226","https://openalex.org/W3029566839","https://openalex.org/W2973640429","https://openalex.org/W1978601326","https://openalex.org/W1982105116","https://openalex.org/W2154390796"],"abstract_inverted_index":{"Jacob,":[0,248],"the":[1,5,25,78,82,98,163,213,225,229],"protein":[2,29,65,198],"encoded":[3],"by":[4,48],"Nsmf":[6,99,188],"gene,":[7],"is":[8],"involved":[9],"in":[10,36,68,135,151,168,172,177,216,233],"synapto-nuclear":[11],"signaling":[12],"and":[13,121,133,155,182,197,252],"docks":[14],"an":[15,169],"N-Methyl-D-Aspartate":[16],"receptor":[17],"(NMDAR)-derived":[18],"signalosome":[19],"to":[20,40,81,107,259],"nuclear":[21,164,245],"target":[22],"sites":[23],"like":[24],"transcription":[26],"factor":[27,140],"cAMP-response-element-binding":[28],"(CREB).":[30],"Several":[31],"reports":[32],"indicate":[33],"that":[34,63,91,93,160,228],"mutations":[35],"NSMF":[37],"are":[38,94],"related":[39,106],"Kallmann":[41],"syndrome":[42],"(KS),":[43],"a":[44,64,116,148,237],"neurodevelopmental":[45],"disorder":[46],"characterized":[47],"idiopathic":[49],"hypogonadotropic":[50],"hypogonadism":[51],"(IHH)":[52],"associated":[53],"with":[54,115],"anosmia":[55],"or":[56],"hyposmia.":[57],"It":[58],"has":[59],"also":[60],"been":[61],"reported":[62],"knockdown":[66],"results":[67,176],"migration":[69],"deficits":[70,134,215],"of":[71,119,123,143,166,180,221,231,247,250],"Gonadotropin-releasing":[72],"hormone":[73],"(GnRH)":[74],"positive":[75,238],"neurons":[76,219],"from":[77],"olfactory":[79],"bulb":[80],"hypothalamus":[83],"during":[84,206],"early":[85,173,234],"neuronal":[86],"development.":[87],"Here":[88],"we":[89],"show":[90,192],"mice":[92,111,191],"constitutively":[95],"deficient":[96],"for":[97],"gene":[100,145,186,255],"do":[101],"not":[102],"present":[103],"phenotypic":[104],"characteristics":[105],"KS.":[108],"Instead,":[109],"these":[110],"exhibit":[112],"hippocampal":[113,126,152,194,217,260],"dysplasia":[114],"reduced":[117,125,193,203],"number":[118],"synapses":[120,132],"simplification":[122],"dendrites,":[124],"long-term":[127],"potentiation":[128],"(LTP)":[129],"at":[130],"CA1":[131,153],"hippocampus-dependent":[136],"learning.":[137],"Brain-derived":[138],"neurotrophic":[139],"(BDNF)":[141],"activation":[142,249],"CREB-activated":[144],"expression":[146],"plays":[147],"documented":[149],"role":[150],"synapse":[154],"dendrite":[156],"formation.":[157],"We":[158],"found":[159],"BDNF":[161,209,242],"induces":[162],"translocation":[165],"Jacob":[167,232],"NMDAR-dependent":[170],"manner":[171],"development,":[174],"which":[175],"increased":[178],"phosphorylation":[179],"CREB":[181,251],"enhanced":[183,253],"CREB-dependent":[184],"Bdnf":[185,195,254],"transcription.":[187],"knockout":[189],"(ko)":[190],"mRNA":[196],"levels":[199,205],"as":[200,202],"well":[201],"pCREB":[204],"dendritogenesis.":[207],"Moreover,":[208],"application":[210],"can":[211],"rescue":[212],"morphological":[214],"pyramidal":[218],"devoid":[220],"Jacob.":[222],"Taken":[223],"together,":[224],"data":[226],"suggest":[227],"absence":[230],"development":[235],"interrupts":[236],"feedback":[239],"loop":[240],"between":[241],"signaling,":[243],"subsequent":[244],"import":[246],"transcription,":[256],"ultimately":[257],"leading":[258],"dysplasia.":[261]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}